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PHARMACOKINETICS OF ATORVASTATIN AND ITS HYDROXY METABOLITES IN RATS AND THE EFFECTS OF CONCOMITANT RIFAMPICIN SINGLE DOSES: RELEVANCE OF FIRST-PASS EFFECT FROM HEPATIC UPTAKE TRANSPORTERS, AND INTESTINAL AND HEPATIC METABOLISM

Yvonne Y. Lau, Hideaki Okochi, Yong Huang and Leslie Z. Benet
Drug Metabolism and Disposition July 2006, 34 (7) 1175-1181; DOI: https://doi.org/10.1124/dmd.105.009076
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Research ArticleArticle

PHARMACOKINETICS OF ATORVASTATIN AND ITS HYDROXY METABOLITES IN RATS AND THE EFFECTS OF CONCOMITANT RIFAMPICIN SINGLE DOSES: RELEVANCE OF FIRST-PASS EFFECT FROM HEPATIC UPTAKE TRANSPORTERS, AND INTESTINAL AND HEPATIC METABOLISM

Yvonne Y. Lau, Hideaki Okochi, Yong Huang and Leslie Z. Benet
Drug Metabolism and Disposition July 1, 2006, 34 (7) 1175-1181; DOI: https://doi.org/10.1124/dmd.105.009076
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