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Research ArticleArticle

IN SILICO PREDICTION OF DRUG BINDING TO CYP2D6: IDENTIFICATION OF A NEW METABOLITE OF METOCLOPRAMIDE

Jinglei Yu, Mark J. I. Paine, Jean-Didier Maréchal, Carol A. Kemp, Clive J. Ward, Simon Brown, Michael J. Sutcliffe, Gordon C. K. Roberts, Elaine M. Rankin and C. Roland Wolf
Drug Metabolism and Disposition August 2006, 34 (8) 1386-1392; DOI: https://doi.org/10.1124/dmd.106.009852
Jinglei Yu
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Mark J. I. Paine
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Jean-Didier Maréchal
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Carol A. Kemp
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Clive J. Ward
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Simon Brown
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Michael J. Sutcliffe
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Gordon C. K. Roberts
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Elaine M. Rankin
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C. Roland Wolf
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Article Information

vol. 34 no. 8 1386-1392
DOI 
https://doi.org/10.1124/dmd.106.009852
PubMed 
16698891

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 24, 2006
  • Accepted May 9, 2006
  • Published online July 17, 2006.

Article Versions

  • Earlier version (May 12, 2006 - 08:20).
  • You are viewing the most recent version of this article.
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The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jinglei Yu1,
  2. Mark J. I. Paine1,
  3. Jean-Didier Maréchal,
  4. Carol A. Kemp,
  5. Clive J. Ward,
  6. Simon Brown,
  7. Michael J. Sutcliffe,
  8. Gordon C. K. Roberts,
  9. Elaine M. Rankin and
  10. C. Roland Wolf
  1. Division of Cancer Medicine (J.Y., C.J.W., S.B., E.M.R.) and Molecular Pharmacology Unit (M.J.I.P., C.R.W.), Biomedical Research Centre, University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom; Manchester Interdisciplinary Biocentre, School of Chemical Engineering and Analytical Science, University of Manchester, the Mill, Manchester, United Kingdom (J.-D.M., M.J.S.); and Department of Biochemistry, University of Leicester, Leicester, United Kingdom (C.A.K., G.C.K.R.)
  1. Address correspondence to:
    C. R. Wolf, Biomedical Research Centre, University of Dundee, Ninewells Hospital & Medical School, Dundee, DD1 9SY, UK. E-mail: roland.wolf{at}cancer.org.uk
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Drug Metabolism and Disposition: 34 (8)
Drug Metabolism and Disposition
Vol. 34, Issue 8
1 Aug 2006
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Research ArticleArticle

IN SILICO PREDICTION OF DRUG BINDING TO CYP2D6: IDENTIFICATION OF A NEW METABOLITE OF METOCLOPRAMIDE

Jinglei Yu, Mark J. I. Paine, Jean-Didier Maréchal, Carol A. Kemp, Clive J. Ward, Simon Brown, Michael J. Sutcliffe, Gordon C. K. Roberts, Elaine M. Rankin and C. Roland Wolf
Drug Metabolism and Disposition August 1, 2006, 34 (8) 1386-1392; DOI: https://doi.org/10.1124/dmd.106.009852

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Research ArticleArticle

IN SILICO PREDICTION OF DRUG BINDING TO CYP2D6: IDENTIFICATION OF A NEW METABOLITE OF METOCLOPRAMIDE

Jinglei Yu, Mark J. I. Paine, Jean-Didier Maréchal, Carol A. Kemp, Clive J. Ward, Simon Brown, Michael J. Sutcliffe, Gordon C. K. Roberts, Elaine M. Rankin and C. Roland Wolf
Drug Metabolism and Disposition August 1, 2006, 34 (8) 1386-1392; DOI: https://doi.org/10.1124/dmd.106.009852
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