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Index by author

September 01, 2006; Volume 34,Issue 9

A

  1. Akita, Hidetaka

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  2. Ando, Yosuke

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  3. Arakawa, Shingo

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  4. Atkins, William M.

    1. A Theoretical Validation of the Substrate Depletion Approach to Determining Kinetic Parameters
      Abhinav Nath and William M. Atkins
      Drug Metabolism and Disposition September 2006, 34 (9) 1433-1435; DOI: https://doi.org/10.1124/dmd.106.010777

B

  1. Balani, Suresh K.

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  2. Beattie, Iain G.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  3. Becker, Stacey L.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  4. Bernard, Olivier

    1. Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid
      Olivier Bernard, Jelena Tojcic, Kim Journault, Louis Perusse and Chantal Guillemette
      Drug Metabolism and Disposition September 2006, 34 (9) 1539-1545; DOI: https://doi.org/10.1124/dmd.106.010553

  5. Bernstein, Michael A.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  6. Bi, Yi-an

    1. Use of Cryopreserved Human Hepatocytes in Sandwich Culture to Measure Hepatobiliary Transport
      Yi-an Bi, Diana Kazolias and David B. Duignan
      Drug Metabolism and Disposition September 2006, 34 (9) 1658-1665; DOI: https://doi.org/10.1124/dmd.105.009118

  7. Boström, Emma

    1. In Vivo Blood-Brain Barrier Transport of Oxycodone in the Rat: Indications for Active Influx and Implications for Pharmacokinetics/Pharmacodynamics
      Emma Boström, Ulrika S. H. Simonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2006, 34 (9) 1624-1631; DOI: https://doi.org/10.1124/dmd.106.009746

C

  1. Callegari, Ernesto

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  2. Carr, Brian

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  3. Castell, José V.

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  4. Chan, Eli

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  5. Chen, Chi

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  6. Chen, Cuiping

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  7. Chen, Jie

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  8. Chen, Shuqing

    1. Genetic Variants of Human UGT1A3: Functional Characterization and Frequency Distribution in a Chinese Han Population
      Yakun Chen, Shuqing Chen, Xin Li, Xiewei Wang and Su Zeng
      Drug Metabolism and Disposition September 2006, 34 (9) 1462-1467; DOI: https://doi.org/10.1124/dmd.106.009761

  9. Chen, Xi

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  10. Chen, Xianghai

    1. P-Glycoprotein and an Unstirred Water Layer Barring Digoxin Absorption in the Vascularly Perfused Rat Small Intestine Preparation: Induction Studies with Pregnenolone-16α-carbonitrile
      Shanjun Liu, Debbie Tam, Xianghai Chen and K. Sandy Pang
      Drug Metabolism and Disposition September 2006, 34 (9) 1468-1479; DOI: https://doi.org/10.1124/dmd.105.008227

  11. Chen, Xiao

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  12. Chen, Yakun

    1. Genetic Variants of Human UGT1A3: Functional Characterization and Frequency Distribution in a Chinese Han Population
      Yakun Chen, Shuqing Chen, Xin Li, Xiewei Wang and Su Zeng
      Drug Metabolism and Disposition September 2006, 34 (9) 1462-1467; DOI: https://doi.org/10.1124/dmd.106.009761

  13. Cho, Taehyeon M.

    1. Inhibition of the Human Liver Microsomal and Human Cytochrome P450 1A2 and 3A4 Metabolism of Estradiol by Deployment-Related and Other Chemicals
      Khawja A. Usmani, Taehyeon M. Cho, Randy L. Rose and Ernest Hodgson
      Drug Metabolism and Disposition September 2006, 34 (9) 1606-1614; DOI: https://doi.org/10.1124/dmd.106.010439

  14. Cianfrogna, Julie

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

D

  1. Dean, Dennis

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  2. Donato, M. Teresa

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  3. Doran, Angela C.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  4. Doran, Shawn D.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  5. Drescher, Anja

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  6. Duan, Wei

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  7. Duignan, David B.

    1. Use of Cryopreserved Human Hepatocytes in Sandwich Culture to Measure Hepatobiliary Transport
      Yi-an Bi, Diana Kazolias and David B. Duignan
      Drug Metabolism and Disposition September 2006, 34 (9) 1658-1665; DOI: https://doi.org/10.1124/dmd.105.009118

  8. Dunbar, Anwar Y.

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

F

  1. Fate, Gwendolyn D.

    1. Using a Tritiated Compound to Elucidate Its Preclinical Metabolic and Excretory Pathways in Vivo: Exploring Tritium Exchange Risk
      Christopher L. Shaffer, Mithat Gunduz, Bruce A. Thornburgh and Gwendolyn D. Fate
      Drug Metabolism and Disposition September 2006, 34 (9) 1615-1623; DOI: https://doi.org/10.1124/dmd.106.010934

  2. Finel, Moshe

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

  3. Franklin, Ronald B.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  4. Fujimoto, Kazunori

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

G

  1. Gallegos, Richard

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  2. Gan, Liang-Shang

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  3. Gibbs, John P.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201
    2. Minimizing Polymorphic Metabolism in Drug Discovery: Evaluation of the Utility of in Vitro Methods for Predicting Pharmacokinetic Consequences Associated with CYP2D6 Metabolism
      John P. Gibbs, Ruth Hyland and Kuresh Youdim
      Drug Metabolism and Disposition September 2006, 34 (9) 1516-1522; DOI: https://doi.org/10.1124/dmd.105.008714

  4. Gómez-Lechón, M. José

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  5. Gonzalez, Frank J.

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  6. Guillemette, Chantal

    1. Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid
      Olivier Bernard, Jelena Tojcic, Kim Journault, Louis Perusse and Chantal Guillemette
      Drug Metabolism and Disposition September 2006, 34 (9) 1539-1545; DOI: https://doi.org/10.1124/dmd.106.010553

  7. Gunduz, Mithat

    1. Using a Tritiated Compound to Elucidate Its Preclinical Metabolic and Excretory Pathways in Vivo: Exploring Tritium Exchange Risk
      Christopher L. Shaffer, Mithat Gunduz, Bruce A. Thornburgh and Gwendolyn D. Fate
      Drug Metabolism and Disposition September 2006, 34 (9) 1615-1623; DOI: https://doi.org/10.1124/dmd.106.010934

H

  1. Haberl, Michael

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  2. Hammarlund-Udenaes, Margareta

    1. In Vivo Blood-Brain Barrier Transport of Oxycodone in the Rat: Indications for Active Influx and Implications for Pharmacokinetics/Pharmacodynamics
      Emma Boström, Ulrika S. H. Simonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2006, 34 (9) 1624-1631; DOI: https://doi.org/10.1124/dmd.106.009746

  3. Hara, Ayako

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  4. Hayashi, Hisamitsu

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  5. He, Ming

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  6. Heining, Peter

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

  7. Hodgson, Ernest

    1. Inhibition of the Human Liver Microsomal and Human Cytochrome P450 1A2 and 3A4 Metabolism of Estradiol by Deployment-Related and Other Chemicals
      Khawja A. Usmani, Taehyeon M. Cho, Randy L. Rose and Ernest Hodgson
      Drug Metabolism and Disposition September 2006, 34 (9) 1606-1614; DOI: https://doi.org/10.1124/dmd.106.010439

  8. Hofmann, Alan F.

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  9. Hollenberg, Paul F.

    1. Mechanism of Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Jan L. Wahlstrom, Paul F. Hollenberg and Larry C. Wienkers
      Drug Metabolism and Disposition September 2006, 34 (9) 1523-1529; DOI: https://doi.org/10.1124/dmd.106.010579

  10. Hosea, Natilie

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  11. Hu, Ze-Ping

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  12. Huang, Min

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  13. Hutson, Janine R.

    1. Regulation of Constitutive Mouse Hepatic Cytochromes P450 and Growth Hormone Signaling Components by 3-Methylcholanthrene
      Chunja Lee, Janine R. Hutson, Vivien Kok-Fung Tzau and David S. Riddick
      Drug Metabolism and Disposition September 2006, 34 (9) 1530-1538; DOI: https://doi.org/10.1124/dmd.106.009936

  14. Hyland, Ruth

    1. Minimizing Polymorphic Metabolism in Drug Discovery: Evaluation of the Utility of in Vitro Methods for Predicting Pharmacokinetic Consequences Associated with CYP2D6 Metabolism
      John P. Gibbs, Ruth Hyland and Kuresh Youdim
      Drug Metabolism and Disposition September 2006, 34 (9) 1516-1522; DOI: https://doi.org/10.1124/dmd.105.008714

I

  1. Idle, Jeffrey R.

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  2. Irth, H.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

  3. Iwabuchi, Haruo

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

J

  1. Jenkins, Gary J.

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

  2. Jianmongkol, Suree

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

  3. Jiménez, Nuria

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  4. Jones, Allen N.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  5. Journault, Kim

    1. Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid
      Olivier Bernard, Jelena Tojcic, Kim Journault, Louis Perusse and Chantal Guillemette
      Drug Metabolism and Disposition September 2006, 34 (9) 1539-1545; DOI: https://doi.org/10.1124/dmd.106.010553

  6. Jung, Diana

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  7. Jushchyshyn, Monica I.

    1. Mechanism of Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Jan L. Wahlstrom, Paul F. Hollenberg and Larry C. Wienkers
      Drug Metabolism and Disposition September 2006, 34 (9) 1523-1529; DOI: https://doi.org/10.1124/dmd.106.010579

  8. Jusko, William J.

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

K

  1. Kazolias, Diana

    1. Use of Cryopreserved Human Hepatocytes in Sandwich Culture to Measure Hepatobiliary Transport
      Yi-an Bi, Diana Kazolias and David B. Duignan
      Drug Metabolism and Disposition September 2006, 34 (9) 1658-1665; DOI: https://doi.org/10.1124/dmd.105.009118

  2. Keil, Andrea

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  3. Kerb, Reinhold

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  4. Kessler, Fay K.

    1. Characterization of Rat Intestinal Microsomal UDP-Glucuronosyltransferase Activity toward Mycophenolic Acid
      Kristini K. Miles, Fay K. Kessler, Philip C. Smith and Joseph K. Ritter
      Drug Metabolism and Disposition September 2006, 34 (9) 1632-1639; DOI: https://doi.org/10.1124/dmd.106.010140

  5. Kochansky, Christopher J.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  6. Kool, J.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

  7. Kostiainen, Risto

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

  8. Krausz, Kristopher W.

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  9. Kullak-Ublick, Gerd A.

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  10. Kuo, Yuhsin

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

L

  1. Lahoz, Agustín

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  2. Lang, Thomas

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  3. Lasseter, Kenneth

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  4. Lau, Miranda

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

  5. Lee, Anna M.

    1. In Vivo and in Vitro Characterization of Chlorzoxazone Metabolism and Hepatic CYP2E1 Levels in African Green Monkeys: Induction by Chronic Nicotine Treatment
      Anna M. Lee, Jiang Yue and Rachel F. Tyndale
      Drug Metabolism and Disposition September 2006, 34 (9) 1508-1515; DOI: https://doi.org/10.1124/dmd.106.010363

  6. Lee, Chunja

    1. Regulation of Constitutive Mouse Hepatic Cytochromes P450 and Growth Hormone Signaling Components by 3-Methylcholanthrene
      Chunja Lee, Janine R. Hutson, Vivien Kok-Fung Tzau and David S. Riddick
      Drug Metabolism and Disposition September 2006, 34 (9) 1530-1538; DOI: https://doi.org/10.1124/dmd.106.009936

  7. Lee, Kuo-Hsiung

    1. Structural Characterization of Anti-HIV Drug Candidate PA-457 [3-O-(3′,3′-Dimethylsuccinyl)-betulinic acid] and Its Acyl Glucuronides in Rat Bile and Evaluation of in Vitro Stability in Human and Animal Liver Microsomes and Plasma
      Zhiming Wen, Stephan T. Stern, David E. Martin, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition September 2006, 34 (9) 1436-1442; DOI: https://doi.org/10.1124/dmd.106.009233

  8. Lewis, Richard J.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  9. Li, Chunze

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  10. Li, Hongshan

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

  11. Li, Ping

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  12. Li, Xin

    1. Genetic Variants of Human UGT1A3: Functional Characterization and Frequency Distribution in a Chinese Han Population
      Yakun Chen, Shuqing Chen, Xin Li, Xiewei Wang and Su Zeng
      Drug Metabolism and Disposition September 2006, 34 (9) 1462-1467; DOI: https://doi.org/10.1124/dmd.106.009761

  13. Lin, Jiunn H.

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  14. Liu, Jianhua

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  15. Liu, Shanjun

    1. P-Glycoprotein and an Unstirred Water Layer Barring Digoxin Absorption in the Vascularly Perfused Rat Small Intestine Preparation: Induction Studies with Pregnenolone-16α-carbonitrile
      Shanjun Liu, Debbie Tam, Xianghai Chen and K. Sandy Pang
      Drug Metabolism and Disposition September 2006, 34 (9) 1468-1479; DOI: https://doi.org/10.1124/dmd.105.008227

  16. Liu, Xingrong

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  17. Lowe, Ezra R.

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

  18. Lowe, Philip

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

  19. Lu, Bing

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  20. Lu, Chuang

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  21. Luukkanen, Leena

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

M

  1. Manabe, Sunao

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  2. Martin, Craig A.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  3. Martin, David E.

    1. Structural Characterization of Anti-HIV Drug Candidate PA-457 [3-O-(3′,3′-Dimethylsuccinyl)-betulinic acid] and Its Acyl Glucuronides in Rat Bile and Evaluation of in Vitro Stability in Human and Animal Liver Microsomes and Plasma
      Zhiming Wen, Stephan T. Stern, David E. Martin, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition September 2006, 34 (9) 1436-1442; DOI: https://doi.org/10.1124/dmd.106.009233

  4. Martin, Iain J.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  5. McPhail, Kerry L.

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  6. Meno-Tetang, Guy M. L.

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

  7. Miida, Hiroaki

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  8. Miles, Kristini K.

    1. Characterization of Rat Intestinal Microsomal UDP-Glucuronosyltransferase Activity toward Mycophenolic Acid
      Kristini K. Miles, Fay K. Kessler, Philip C. Smith and Joseph K. Ritter
      Drug Metabolism and Disposition September 2006, 34 (9) 1632-1639; DOI: https://doi.org/10.1124/dmd.106.010140

  9. Mir, José

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  10. Mis, Suzette

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

  11. Mita, Sachiko

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  12. Miwa, Gerald T.

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  13. Mornhinweg, Esther

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

N

  1. Nakatsuka, Mikiya

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

  2. Nath, Abhinav

    1. A Theoretical Validation of the Substrate Depletion Approach to Determining Kinetic Parameters
      Abhinav Nath and William M. Atkins
      Drug Metabolism and Disposition September 2006, 34 (9) 1433-1435; DOI: https://doi.org/10.1124/dmd.106.010777

  3. Nelson, Frederick R.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  4. Niessen, W. M. A.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

O

  1. Onuki, Reiko

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  2. Osawa, Yoichi

    1. Tetrahydrobiopterin Protects against Guanabenz-Mediated Inhibition of Neuronal Nitric-Oxide Synthase in Vitro and in Vivo
      Anwar Y. Dunbar, Gary J. Jenkins, Suree Jianmongkol, Mikiya Nakatsuka, Ezra R. Lowe, Miranda Lau and Yoichi Osawa
      Drug Metabolism and Disposition September 2006, 34 (9) 1448-1456; DOI: https://doi.org/10.1124/dmd.106.009951

P

  1. Pang, K. Sandy

    1. P-Glycoprotein and an Unstirred Water Layer Barring Digoxin Absorption in the Vascularly Perfused Rat Small Intestine Preparation: Induction Studies with Pregnenolone-16α-carbonitrile
      Shanjun Liu, Debbie Tam, Xianghai Chen and K. Sandy Pang
      Drug Metabolism and Disposition September 2006, 34 (9) 1468-1479; DOI: https://doi.org/10.1124/dmd.105.008227

  2. Pérez, Gabriela

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  3. Perlík, František

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  4. Perusse, Louis

    1. Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid
      Olivier Bernard, Jelena Tojcic, Kim Journault, Louis Perusse and Chantal Guillemette
      Drug Metabolism and Disposition September 2006, 34 (9) 1539-1545; DOI: https://doi.org/10.1124/dmd.106.010553

  5. Prueksaritanont, Thomayant

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  6. Pyszczynski, Nancy

    1. Physiologically Based Pharmacokinetic Modeling of FTY720 (2-Amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in Rats After Oral and Intravenous Doses
      Guy M. L. Meno-Tetang, Hongshan Li, Suzette Mis, Nancy Pyszczynski, Peter Heining, Philip Lowe and William J. Jusko
      Drug Metabolism and Disposition September 2006, 34 (9) 1480-1487; DOI: https://doi.org/10.1124/dmd.105.009001

Q

  1. Qiu, Yue

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  2. Qvisen, Saana

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

R

  1. Richards, Karen

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  2. Riddick, David S.

    1. Regulation of Constitutive Mouse Hepatic Cytochromes P450 and Growth Hormone Signaling Components by 3-Methylcholanthrene
      Chunja Lee, Janine R. Hutson, Vivien Kok-Fung Tzau and David S. Riddick
      Drug Metabolism and Disposition September 2006, 34 (9) 1530-1538; DOI: https://doi.org/10.1124/dmd.106.009936

  3. Riley, Robert J.

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  4. Rippley, Ronda K.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  5. Ritter, Joseph K.

    1. Characterization of Rat Intestinal Microsomal UDP-Glucuronosyltransferase Activity toward Mycophenolic Acid
      Kristini K. Miles, Fay K. Kessler, Philip C. Smith and Joseph K. Ritter
      Drug Metabolism and Disposition September 2006, 34 (9) 1632-1639; DOI: https://doi.org/10.1124/dmd.106.010140

  6. Rose, Randy L.

    1. Inhibition of the Human Liver Microsomal and Human Cytochrome P450 1A2 and 3A4 Metabolism of Estradiol by Deployment-Related and Other Chemicals
      Khawja A. Usmani, Taehyeon M. Cho, Randy L. Rose and Ernest Hodgson
      Drug Metabolism and Disposition September 2006, 34 (9) 1606-1614; DOI: https://doi.org/10.1124/dmd.106.010439

S

  1. Schlagenhaufer, Robert

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  2. Schwartz, Jules

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  3. Serralta, Alfonso

    1. Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts
      M. Teresa Donato, Agustín Lahoz, Nuria Jiménez, Gabriela Pérez, Alfonso Serralta, José Mir, José V. Castell and M. José Gómez-Lechón
      Drug Metabolism and Disposition September 2006, 34 (9) 1556-1562; DOI: https://doi.org/10.1124/dmd.106.009670

  4. Shaffer, Christopher L.

    1. Using a Tritiated Compound to Elucidate Its Preclinical Metabolic and Excretory Pathways in Vivo: Exploring Tritium Exchange Risk
      Christopher L. Shaffer, Mithat Gunduz, Bruce A. Thornburgh and Gwendolyn D. Fate
      Drug Metabolism and Disposition September 2006, 34 (9) 1615-1623; DOI: https://doi.org/10.1124/dmd.106.010934

  5. Sheu, Fwu-Shan

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  6. Shibaya, Yukari

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  7. Simonsson, Ulrika S. H.

    1. In Vivo Blood-Brain Barrier Transport of Oxycodone in the Rat: Indications for Active Influx and Implications for Pharmacokinetics/Pharmacodynamics
      Emma Boström, Ulrika S. H. Simonsson and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2006, 34 (9) 1624-1631; DOI: https://doi.org/10.1124/dmd.106.009746

  8. Slanař, Ondřej

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  9. Slavík, Josef

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  10. Smith, Bill J.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  11. Smith, Philip C.

    1. Structural Characterization of Anti-HIV Drug Candidate PA-457 [3-O-(3′,3′-Dimethylsuccinyl)-betulinic acid] and Its Acyl Glucuronides in Rat Bile and Evaluation of in Vitro Stability in Human and Animal Liver Microsomes and Plasma
      Zhiming Wen, Stephan T. Stern, David E. Martin, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition September 2006, 34 (9) 1436-1442; DOI: https://doi.org/10.1124/dmd.106.009233
    2. Characterization of Rat Intestinal Microsomal UDP-Glucuronosyltransferase Activity toward Mycophenolic Acid
      Kristini K. Miles, Fay K. Kessler, Philip C. Smith and Joseph K. Ritter
      Drug Metabolism and Disposition September 2006, 34 (9) 1632-1639; DOI: https://doi.org/10.1124/dmd.106.010140

  12. Song, Hengchang

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  13. Springthorpe, Brian

    1. Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo
      Iain J. Martin, Richard J. Lewis, Michael A. Bernstein, Iain G. Beattie, Craig A. Martin, Robert J. Riley and Brian Springthorpe
      Drug Metabolism and Disposition September 2006, 34 (9) 1502-1507; DOI: https://doi.org/10.1124/dmd.106.009282

  14. Sten, Taina

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

  15. Stern, Stephan T.

    1. Structural Characterization of Anti-HIV Drug Candidate PA-457 [3-O-(3′,3′-Dimethylsuccinyl)-betulinic acid] and Its Acyl Glucuronides in Rat Bile and Evaluation of in Vitro Stability in Human and Animal Liver Microsomes and Plasma
      Zhiming Wen, Stephan T. Stern, David E. Martin, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition September 2006, 34 (9) 1436-1442; DOI: https://doi.org/10.1124/dmd.106.009233

  16. Stieger, Bruno

    1. Genetic Variability, Haplotype Structures, and Ethnic Diversity of Hepatic Transporters MDR3 (ABCB4) and Bile Salt Export Pump (ABCB11)
      Thomas Lang, Michael Haberl, Diana Jung, Anja Drescher, Robert Schlagenhaufer, Andrea Keil, Esther Mornhinweg, Bruno Stieger, Gerd A. Kullak-Ublick and Reinhold Kerb
      Drug Metabolism and Disposition September 2006, 34 (9) 1582-1599; DOI: https://doi.org/10.1124/dmd.105.008854

  17. Strong-Basalyga, Kristie

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  18. Sugiyama, Yuichi

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  19. Suzuki, Hiroshi

    1. Inhibition of Bile Acid Transport across Na+/Taurocholate Cotransporting Polypeptide (SLC10A1) and Bile Salt Export Pump (ABCB 11)-Coexpressing LLC-PK1 Cells by Cholestasis-Inducing Drugs
      Sachiko Mita, Hiroshi Suzuki, Hidetaka Akita, Hisamitsu Hayashi, Reiko Onuki, Alan F. Hofmann and Yuichi Sugiyama
      Drug Metabolism and Disposition September 2006, 34 (9) 1575-1581; DOI: https://doi.org/10.1124/dmd.105.008748

  20. Szewc, Mark A.

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

T

  1. Takasaki, Wataru

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  2. Tam, Debbie

    1. P-Glycoprotein and an Unstirred Water Layer Barring Digoxin Absorption in the Vascularly Perfused Rat Small Intestine Preparation: Induction Studies with Pregnenolone-16α-carbonitrile
      Shanjun Liu, Debbie Tam, Xianghai Chen and K. Sandy Pang
      Drug Metabolism and Disposition September 2006, 34 (9) 1468-1479; DOI: https://doi.org/10.1124/dmd.105.008227

  3. Tang, Cuyue

    1. In Vitro and in Vivo CYP3A64 Induction and Inhibition Studies in Rhesus Monkeys: A Preclinical Approach for CYP3A-Mediated Drug Interaction Studies
      Thomayant Prueksaritanont, Yuhsin Kuo, Cuyue Tang, Chunze Li, Yue Qiu, Bing Lu, Kristie Strong-Basalyga, Karen Richards, Brian Carr and Jiunn H. Lin
      Drug Metabolism and Disposition September 2006, 34 (9) 1546-1555; DOI: https://doi.org/10.1124/dmd.106.009878

  4. Thornburgh, Bruce A.

    1. Using a Tritiated Compound to Elucidate Its Preclinical Metabolic and Excretory Pathways in Vivo: Exploring Tritium Exchange Risk
      Christopher L. Shaffer, Mithat Gunduz, Bruce A. Thornburgh and Gwendolyn D. Fate
      Drug Metabolism and Disposition September 2006, 34 (9) 1615-1623; DOI: https://doi.org/10.1124/dmd.106.010934

  5. Tojcic, Jelena

    1. Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid
      Olivier Bernard, Jelena Tojcic, Kim Journault, Louis Perusse and Chantal Guillemette
      Drug Metabolism and Disposition September 2006, 34 (9) 1539-1545; DOI: https://doi.org/10.1124/dmd.106.010553

  6. Tyndale, Rachel F.

    1. In Vivo and in Vitro Characterization of Chlorzoxazone Metabolism and Hepatic CYP2E1 Levels in African Green Monkeys: Induction by Chronic Nicotine Treatment
      Anna M. Lee, Jiang Yue and Rachel F. Tyndale
      Drug Metabolism and Disposition September 2006, 34 (9) 1508-1515; DOI: https://doi.org/10.1124/dmd.106.010363

  7. Tzau, Vivien Kok-Fung

    1. Regulation of Constitutive Mouse Hepatic Cytochromes P450 and Growth Hormone Signaling Components by 3-Methylcholanthrene
      Chunja Lee, Janine R. Hutson, Vivien Kok-Fung Tzau and David S. Riddick
      Drug Metabolism and Disposition September 2006, 34 (9) 1530-1538; DOI: https://doi.org/10.1124/dmd.106.009936

U

  1. Uchiyama, Minoru

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  2. Usmani, Khawja A.

    1. Inhibition of the Human Liver Microsomal and Human Cytochrome P450 1A2 and 3A4 Metabolism of Estradiol by Deployment-Related and Other Chemicals
      Khawja A. Usmani, Taehyeon M. Cho, Randy L. Rose and Ernest Hodgson
      Drug Metabolism and Disposition September 2006, 34 (9) 1606-1614; DOI: https://doi.org/10.1124/dmd.106.010439

  3. Uttamsingh, Vinita

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

  4. Uutela, Päivi

    1. Prominent but Reverse Stereoselectivity in Propranolol Glucuronidation by Human UDP-Glucuronosyltransferases 1A9 and 1A10
      Taina Sten, Saana Qvisen, Päivi Uutela, Leena Luukkanen, Risto Kostiainen and Moshe Finel
      Drug Metabolism and Disposition September 2006, 34 (9) 1488-1494; DOI: https://doi.org/10.1124/dmd.106.010371

V

  1. Van Deusen, Jeffrey

    1. Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration
      Xingrong Liu, Bill J. Smith, Cuiping Chen, Ernesto Callegari, Stacey L. Becker, Xi Chen, Julie Cianfrogna, Angela C. Doran, Shawn D. Doran, John P. Gibbs, Natilie Hosea, Jianhua Liu, Frederick R. Nelson, Mark A. Szewc and Jeffrey Van Deusen
      Drug Metabolism and Disposition September 2006, 34 (9) 1443-1447; DOI: https://doi.org/10.1124/dmd.105.008201

  2. van Elswijk, D. E.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

  3. van Liempd, S. M.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

  4. Vermeulen, N. P. E.

    1. On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators
      S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
      Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

  5. Vincent, Stella H.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

W

  1. Wagner, John

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  2. Wahlstrom, Jan L.

    1. Mechanism of Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Jan L. Wahlstrom, Paul F. Hollenberg and Larry C. Wienkers
      Drug Metabolism and Disposition September 2006, 34 (9) 1523-1529; DOI: https://doi.org/10.1124/dmd.106.010579

  3. Wallace, Michael A.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  4. Wang, Xiewei

    1. Genetic Variants of Human UGT1A3: Functional Characterization and Frequency Distribution in a Chinese Han Population
      Yakun Chen, Shuqing Chen, Xin Li, Xiewei Wang and Su Zeng
      Drug Metabolism and Disposition September 2006, 34 (9) 1462-1467; DOI: https://doi.org/10.1124/dmd.106.009761

  5. Wen, Zhiming

    1. Structural Characterization of Anti-HIV Drug Candidate PA-457 [3-O-(3′,3′-Dimethylsuccinyl)-betulinic acid] and Its Acyl Glucuronides in Rat Bile and Evaluation of in Vitro Stability in Human and Animal Liver Microsomes and Plasma
      Zhiming Wen, Stephan T. Stern, David E. Martin, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition September 2006, 34 (9) 1436-1442; DOI: https://doi.org/10.1124/dmd.106.009233

  6. Wienkers, Larry C.

    1. Mechanism of Inactivation of Human Cytochrome P450 2B6 by Phencyclidine
      Monica I. Jushchyshyn, Jan L. Wahlstrom, Paul F. Hollenberg and Larry C. Wienkers
      Drug Metabolism and Disposition September 2006, 34 (9) 1523-1529; DOI: https://doi.org/10.1124/dmd.106.010579

X

  1. Xia, Cindy Q.

    1. Comparison of Intrinsic Clearance in Liver Microsomes and Hepatocytes from Rats and Humans: Evaluation of Free Fraction and Uptake in Hepatocytes
      Chuang Lu, Ping Li, Richard Gallegos, Vinita Uttamsingh, Cindy Q. Xia, Gerald T. Miwa, Suresh K. Balani and Liang-Shang Gan
      Drug Metabolism and Disposition September 2006, 34 (9) 1600-1605; DOI: https://doi.org/10.1124/dmd.106.010793

Y

  1. Yamoto, Takashi

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  2. Yan, Kerri X.

    1. Absorption, Metabolism, and Excretion of [14C]MK-0767 (2-Methoxy-5-(2,4-dioxo-5-thiazolidinyl)-N-[[4-(trifluoromethyl)phenyl] methyl]benzamide) in Humans
      Christopher J. Kochansky, Ronda K. Rippley, Kerri X. Yan, Hengchang Song, Michael A. Wallace, Dennis Dean, Allen N. Jones, Kenneth Lasseter, Jules Schwartz, Stella H. Vincent, Ronald B. Franklin and John Wagner
      Drug Metabolism and Disposition September 2006, 34 (9) 1457-1461; DOI: https://doi.org/10.1124/dmd.106.010231

  3. Yang, Xiao-Xia

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837

  4. Yasumo, Hiroaki

    1. Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene
      Kazunori Fujimoto, Shingo Arakawa, Yukari Shibaya, Hiroaki Miida, Yosuke Ando, Hiroaki Yasumo, Ayako Hara, Minoru Uchiyama, Haruo Iwabuchi, Wataru Takasaki, Sunao Manabe and Takashi Yamoto
      Drug Metabolism and Disposition September 2006, 34 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.106.010009

  5. Youdim, Kuresh

    1. Minimizing Polymorphic Metabolism in Drug Discovery: Evaluation of the Utility of in Vitro Methods for Predicting Pharmacokinetic Consequences Associated with CYP2D6 Metabolism
      John P. Gibbs, Ruth Hyland and Kuresh Youdim
      Drug Metabolism and Disposition September 2006, 34 (9) 1516-1522; DOI: https://doi.org/10.1124/dmd.105.008714

  6. Yue, Jiang

    1. In Vivo and in Vitro Characterization of Chlorzoxazone Metabolism and Hepatic CYP2E1 Levels in African Green Monkeys: Induction by Chronic Nicotine Treatment
      Anna M. Lee, Jiang Yue and Rachel F. Tyndale
      Drug Metabolism and Disposition September 2006, 34 (9) 1508-1515; DOI: https://doi.org/10.1124/dmd.106.010363

Z

  1. Zabriskie, T. Mark

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  2. Zeng, Su

    1. Genetic Variants of Human UGT1A3: Functional Characterization and Frequency Distribution in a Chinese Han Population
      Yakun Chen, Shuqing Chen, Xin Li, Xiewei Wang and Su Zeng
      Drug Metabolism and Disposition September 2006, 34 (9) 1462-1467; DOI: https://doi.org/10.1124/dmd.106.009761

  3. Zhen, Yueying

    1. 3,4-Dehydrodebrisoquine, a Novel Debrisoquine Metabolite Formed from 4-Hydroxydebrisoquine That Affects the CYP2D6 Metabolic Ratio
      Yueying Zhen, Ondřej Slanař, Kristopher W. Krausz, Chi Chen, Josef Slavík, Kerry L. McPhail, T. Mark Zabriskie, František Perlík, Frank J. Gonzalez and Jeffrey R. Idle
      Drug Metabolism and Disposition September 2006, 34 (9) 1563-1574; DOI: https://doi.org/10.1124/dmd.105.008920

  4. Zhou, Shu-Feng

    1. Small Interfering RNA-Mediated Silencing of Cytochrome P450 3A4 Gene
      Jie Chen, Xiao-Xia Yang, Min Huang, Ze-Ping Hu, Ming He, Wei Duan, Eli Chan, Fwu-Shan Sheu, Xiao Chen and Shu-Feng Zhou
      Drug Metabolism and Disposition September 2006, 34 (9) 1650-1657; DOI: https://doi.org/10.1124/dmd.106.009837
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