Evaluation of Cerebrospinal Fluid Concentration and Plasma Free Concentration As a Surrogate Measurement for Brain Free Concentration

Address correspondence to:
Dr. Xingrong Liu, Drug Metabolism and Pharmacokinetics, Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, CA 94304. E-mail: xingrong.liu{at}roche.com

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