Which Hydroxy? Evidence for Species Differences in the Regioselectivity of Glucuronidation in Rat, Dog, and Human in Vitro Systems and Dog in Vivo

Department of Physical and Metabolic Science (I.J.M., R.J.L., M.A.B., I.G.B., C.A.M., R.J.R.) and Department of Medicinal Chemistry (B.S.), AstraZeneca R&D Charnwood, Loughborough, United Kingdom

Address correspondence to:
Dr. Richard J. Lewis, Department of Physical and Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, LE11 5RH, UK. E-mail: Richard.J.Lewis{at}astrazeneca.com

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Jun 2021	11	1	0
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May 2022	18	1	1
Jun 2022	47	4	1