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Research ArticleArticle

On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators

S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
Drug Metabolism and Disposition September 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355

Article Information

vol. 34 no. 9 1640-1649
DOI 
https://doi.org/10.1124/dmd.106.010355
PubMed 
16790557
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 29, 2006
  • Accepted June 16, 2006
  • Published online August 22, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. S. M. van Liempd,
  2. J. Kool,
  3. W. M. A. Niessen,
  4. D. E. van Elswijk,
  5. H. Irth and
  6. N. P. E. Vermeulen
  1. Leiden/Amsterdam Center for Drug Research, Divisions of Molecular Toxicology (S.M.v.L., J.K., N.P.E.V.) and Biomolecular Analysis (W.M.A.N., H.I.), Vrije Universiteit Amsterdam, The Netherlands; and Kiadis B.V., Groningen, The Netherlands (D.E.v.E., H.I.)
  1. Address correspondence to:
    Prof. Dr. N. P. E. Vermeulen, LACDR-Section of Molecular Toxicology, Department of Chemistry and Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands. E-mail: npe.vermeulen{at}few.vu.nl
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Research ArticleArticle

On-line Formation, Separation, and Estrogen Receptor Affinity Screening of Cytochrome P450-Derived Metabolites of Selective Estrogen Receptor Modulators

S. M. van Liempd, J. Kool, W. M. A. Niessen, D. E. van Elswijk, H. Irth and N. P. E. Vermeulen
Drug Metabolism and Disposition September 1, 2006, 34 (9) 1640-1649; DOI: https://doi.org/10.1124/dmd.106.010355
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