Table of Contents

Articles

• You have access

  Biotransformation of Geldanamycin and 17-Allylamino-17-Demethoxygeldanamycin by Human Liver Microsomes: Reductive versus Oxidative Metabolism and Implications

  Wensheng Lang, Gary W. Caldwell, Jian Li, Gregory C. Leo, William J. Jones and John A. Masucci

  Drug Metabolism and Disposition January 2007, 35 (1) 21-29; DOI: https://doi.org/10.1124/dmd.106.009639
• You have access

  Organic Anion Transporting Polypeptide 2B1 and Breast Cancer Resistance Protein Interact in the Transepithelial Transport of Steroid Sulfates in Human Placenta

  Markus Grube, Sebastian Reuther, Henriette Meyer zu Schwabedissen, Kathleen Köck, Katrin Draber, Christoph A. Ritter, Christoph Fusch, Gabriele Jedlitschky and Heyo K. Kroemer

  Drug Metabolism and Disposition January 2007, 35 (1) 30-35; DOI: https://doi.org/10.1124/dmd.106.011411
• You have access

  Gender Dictates the Nuclear Receptor-Mediated Regulation of CYP3A44

  Sayeepriyadarshini Anakk, Wendong Huang, Jeffrey L. Staudinger, Kheng Tan, Timothy J. Cole, David D. Moore and Henry W. Strobel

  Drug Metabolism and Disposition January 2007, 35 (1) 36-42; DOI: https://doi.org/10.1124/dmd.106.011270
• You have access

  Specificity of Aminoacylase III-Mediated Deacetylation of Mercapturic Acids

  Debra Newman, Natalia Abuladze, Karoline Scholz, Wolfgang Dekant, Vladimir Tsuprun, Sergey Ryazantsev, Galyna Bondar, Pakan Sassani, Ira Kurtz and Alexander Pushkin

  Drug Metabolism and Disposition January 2007, 35 (1) 43-50; DOI: https://doi.org/10.1124/dmd.106.012062
• You have access

  The Disposition and Metabolism of Naveglitazar, a Peroxisome Proliferator-Activated Receptor α-γ Dual, γ-Dominant Agonist in Mice, Rats, and Monkeys

  Ping Yi, Chad E. Hadden, William F. Annes, David A. Jackson, Barry C. Peterson, Todd A. Gillespie and Jason T. Johnson

  Drug Metabolism and Disposition January 2007, 35 (1) 51-61; DOI: https://doi.org/10.1124/dmd.106.012328
• You have access

  Elevated Warfarin Metabolism in Warfarin-Resistant Roof Rats (Rattus rattus) in Tokyo

  Mayumi Ishizuka, Fumie Okajima, Tsutomu Tanikawa, Heewon Min, Kazuyuki D. Tanaka, Kentaro Q. Sakamoto and Shoichi Fujita

  Drug Metabolism and Disposition January 2007, 35 (1) 62-66; DOI: https://doi.org/10.1124/dmd.106.011775
• You have access

  A New CYP3A5 Variant, CYP3A5*11, Is Shown to Be Defective in Nifedipine Metabolism in a Recombinant cDNA Expression System

  Su-Jun Lee, Ilse P. van der Heiden, Joyce A. Goldstein and Ron H. N. van Schaik

  Drug Metabolism and Disposition January 2007, 35 (1) 67-71; DOI: https://doi.org/10.1124/dmd.106.012310
• You have access

  Identification of Human Cytochrome P450 Isozymes Involved in Diphenhydramine N-Demethylation

  Tomoko Akutsu, Kaoru Kobayashi, Koichi Sakurada, Hiroshi Ikegaya, Tomomi Furihata and Kan Chiba

  Drug Metabolism and Disposition January 2007, 35 (1) 72-78; DOI: https://doi.org/10.1124/dmd.106.012088
• You have access

  A Novel Model for the Prediction of Drug-Drug Interactions in Humans Based on in Vitro Cytochrome P450 Phenotypic Data

  Chuang Lu, Gerald T. Miwa, Shimoga R. Prakash, Liang-Shang Gan and Suresh K. Balani

  Drug Metabolism and Disposition January 2007, 35 (1) 79-85; DOI: https://doi.org/10.1124/dmd.106.011346
• You have access

  Humanized IgG₁ Variants with Differential Binding Properties to the Neonatal Fc Receptor: Relationship to Pharmacokinetics in Mice and Primates

  Amita Datta-Mannan, Derrick R. Witcher, Ying Tang, Jeffry Watkins, Weidong Jiang and Victor J. Wroblewski

  Drug Metabolism and Disposition January 2007, 35 (1) 86-94; DOI: https://doi.org/10.1124/dmd.106.011734
• You have access

  Pregnane X Receptor-Dependent Induction of the CYP3A4 Gene by o,p′-1,1,1,-Trichloro-2,2-Bis (p-Chlorophenyl)ethane

  Irma M. Medina-Díaz, Georgina Arteaga-Illán, Mario Bermudez de León, Bulmaro Cisneros, Adolfo Sierra-Santoyo, Libia Vega, Frank J. Gonzalez and Guillermo Elizondo

  Drug Metabolism and Disposition January 2007, 35 (1) 95-102; DOI: https://doi.org/10.1124/dmd.106.011759
• You have access

  A Real-Time Fluorescence Assay for Measuring N-Dealkylation

  Richard T. Mayer, E. Kurt Dolence and Gabriele E. Mayer

  Drug Metabolism and Disposition January 2007, 35 (1) 103-109; DOI: https://doi.org/10.1124/dmd.106.011601
• You have access

  Impact of Curcumin-Induced Changes in P-Glycoprotein and CYP3A Expression on the Pharmacokinetics of Peroral Celiprolol and Midazolam in Rats

  Wenxia Zhang, Theresa May Chin Tan and Lee-Yong Lim

  Drug Metabolism and Disposition January 2007, 35 (1) 110-115; DOI: https://doi.org/10.1124/dmd.106.011072
• You have access

  Isolation of the UDP-Glucuronosyltransferase 1A3 and 1A4 Proximal Promoters and Characterization of Their Dependence on the Transcription Factor Hepatocyte Nuclear Factor 1α

  Dione A. Gardner-Stephen and Peter I. Mackenzie

  Drug Metabolism and Disposition January 2007, 35 (1) 116-120; DOI: https://doi.org/10.1124/dmd.106.012203
• You have access

  Tissue- and Gender-Specific mRNA Expression of UDP-Glucuronosyltransferases (UGTs) in Mice

  David B. Buckley and Curtis D. Klaassen

  Drug Metabolism and Disposition January 2007, 35 (1) 121-127; DOI: https://doi.org/10.1124/dmd.106.012070
• You have access

  CYP2B6, CYP2D6, and CYP3A4 Catalyze the Primary Oxidative Metabolism of Perhexiline Enantiomers by Human Liver Microsomes

  Benjamin J. Davies, Janet K. Coller, Andrew A. Somogyi, Robert W. Milne and Benedetta C. Sallustio

  Drug Metabolism and Disposition January 2007, 35 (1) 128-138; DOI: https://doi.org/10.1124/dmd.106.012252
• You have access

  Involvement of Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes in the in Vitro Metabolism of Muraglitazar

  Donglu Zhang, Lifei Wang, Gamini Chandrasena, Li Ma, Mingshe Zhu, Hongjian Zhang, Carl D. Davis and W. Griffith Humphreys

  Drug Metabolism and Disposition January 2007, 35 (1) 139-149; DOI: https://doi.org/10.1124/dmd.106.011932
• You have access

  Comparative Metabolism of Radiolabeled Muraglitazar in Animals and Humans by Quantitative and Qualitative Metabolite Profiling

  Donglu Zhang, Lifei Wang, Nirmala Raghavan, Haiying Zhang, Wenying Li, Peter T. Cheng, Ming Yao, Litao Zhang, Mingshe Zhu, Samuel Bonacorsi, Suresh Yeola, James Mitroka, Narayanan Hariharan, Vinayak Hosagrahara, Gamini Chandrasena, Wen Chyi Shyu and W. Griffith Humphreys

  Drug Metabolism and Disposition January 2007, 35 (1) 150-167; DOI: https://doi.org/10.1124/dmd.106.012450
• You have access

  Cytochrome P450 and Glutathione S-Transferase mRNA Expression in Human Fetal Liver Hematopoietic Stem Cells

  Jing Shao, Patricia L. Stapleton, Yvonne S. Lin and Evan P. Gallagher

  Drug Metabolism and Disposition January 2007, 35 (1) 168-175; DOI: https://doi.org/10.1124/dmd.106.012757
• You have access

  Genetic Variation of Human Cytochrome P450 Reductase as a Potential Biomarker for Mitomycin C-Induced Cytotoxicity

  Shou-Lin Wang, Jing-Fen Han, Xiao-Yang He, Xin-Ru Wang and Jun-Yan Hong

  Drug Metabolism and Disposition January 2007, 35 (1) 176-179; DOI: https://doi.org/10.1124/dmd.106.011056
• You have access

  An Evaluation of the Cytochrome P450 Inhibition Potential of Lisdexamfetamine in Human Liver Microsomes

  Suma Krishnan and Scott Moncrief

  Drug Metabolism and Disposition January 2007, 35 (1) 180-184; DOI: https://doi.org/10.1124/dmd.106.011973