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Drug Metabolism & Disposition

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Index by author

October 01, 2007; Volume 35,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abraham, Trent

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Intestinal Peptide Transporter 1 (SLC15A1)-Targeted Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2-Amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in Rats and Dogs: Assessment of First-Pass Bioactivation and Dose Linearity
      Everett J. Perkins and Trent Abraham
      Drug Metabolism and Disposition October 2007, 35 (10) 1903-1909; DOI: https://doi.org/10.1124/dmd.107.016154
  2. Adachi, Mayuko

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  3. Aimová, Dagmar

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  4. Akao, Teruaki

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  5. Akasawa, Akira

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  6. Aleksunes, Lauren M.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
    2. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  7. Alvarez, Ana I.

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  8. Amin, Shantu

    1. You have access
      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  9. Ando, Tomohiro

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  10. Augustine, Lisa

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  11. Augustine, Lisa M.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  12. Axelsson, Bengt-Olof

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297

B

  1. Bai, Stephen A.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  2. Bakhiya, Nadiya

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  3. Banks, Matthew L.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261
  4. Barnes, Sarah N.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  5. Barter, Z. E.

    1. You have access
      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743
  6. Batke, Monika

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  7. Bayliss, M. K.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  8. Besselsen, David G.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  9. Bhadhprasit, Wattanaporn

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832
  10. Black, Christopher B.

    1. You have access
      In Vitro Prediction and in Vivo Verification of Enantioselective Human Tofisopam Metabolite Profiles
      Michael D. Cameron, Jason Wright, Christopher B. Black and Naidong Ye
      Drug Metabolism and Disposition October 2007, 35 (10) 1894-1902; DOI: https://doi.org/10.1124/dmd.107.015875
  11. Brogdon, Bernice

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  12. Brüggemann, Svenja Kristin

    1. You have access
      Influence of Short-Term Use of Dexamethasone on the Pharmacokinetics of Ifosfamide in Patients
      Svenja Kristin Brüggemann, Sonja Pfäffle, Stefan Oliver Peters and Thomas Wagner
      Drug Metabolism and Disposition October 2007, 35 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.106.014043
  13. Buerger, C.

    1. You have access
      Does Linezolid Inhibit Its Own Metabolism?—Population Pharmacokinetics As a Tool to Explain the Observed Nonlinearity in Both Healthy Volunteers and Septic Patients
      N. Plock, C. Buerger, C. Joukhadar, S. Kljucar and C. Kloft
      Drug Metabolism and Disposition October 2007, 35 (10) 1816-1823; DOI: https://doi.org/10.1124/dmd.106.013755

C

  1. Cameron, Michael D.

    1. You have access
      In Vitro Prediction and in Vivo Verification of Enantioselective Human Tofisopam Metabolite Profiles
      Michael D. Cameron, Jason Wright, Christopher B. Black and Naidong Ye
      Drug Metabolism and Disposition October 2007, 35 (10) 1894-1902; DOI: https://doi.org/10.1124/dmd.107.015875
  2. Cellucci, Antonella

    1. You have access
      High-Throughput Radiometric CYP2C19 Inhibition Assay Using Tritiated (S)-Mephenytoin
      Annalise Di Marco, Antonella Cellucci, Ashok Chaudhary, Massimiliano Fonsi and Ralph Laufer
      Drug Metabolism and Disposition October 2007, 35 (10) 1737-1743; DOI: https://doi.org/10.1124/dmd.107.016345
  3. Chaudhary, Ashok

    1. You have access
      High-Throughput Radiometric CYP2C19 Inhibition Assay Using Tritiated (S)-Mephenytoin
      Annalise Di Marco, Antonella Cellucci, Ashok Chaudhary, Massimiliano Fonsi and Ralph Laufer
      Drug Metabolism and Disposition October 2007, 35 (10) 1737-1743; DOI: https://doi.org/10.1124/dmd.107.016345
  4. Chen, Cuiping

    1. You have access
      P-glycoprotein Has Differential Effects on the Disposition of Statin Acid and Lactone Forms in mdr1a/b Knockout and Wild-Type Mice
      Cuiping Chen, Jian Lin, Teresa Smolarek and Larry Tremaine
      Drug Metabolism and Disposition October 2007, 35 (10) 1725-1729; DOI: https://doi.org/10.1124/dmd.107.015677
  5. Chen, Gang

    1. You have access
      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  6. Cherrington, Nathan J.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
    2. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  7. Chovan, James P.

    1. You have access
      Metabolic Profile of [14C]Bendamustine in Rat Urine and Bile: Preliminary Structural Identification of Metabolites
      James P. Chovan, Feng Li, Erya Yu and Steven C. Ring
      Drug Metabolism and Disposition October 2007, 35 (10) 1744-1753; DOI: https://doi.org/10.1124/dmd.107.015958
  8. Christ, David D.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  9. Covington, Maryanne B.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  10. Czoty, Paul W.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261

D

  1. De Buck, Stefan S.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644
  2. Decicco, Carl P.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  3. Degawa, Masakuni

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  4. Deng, Yuzhong

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  5. Desai, Pankaj

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089
  6. Di Marco, Annalise

    1. You have access
      High-Throughput Radiometric CYP2C19 Inhibition Assay Using Tritiated (S)-Mephenytoin
      Annalise Di Marco, Antonella Cellucci, Ashok Chaudhary, Massimiliano Fonsi and Ralph Laufer
      Drug Metabolism and Disposition October 2007, 35 (10) 1737-1743; DOI: https://doi.org/10.1124/dmd.107.016345
  7. Dixit, Vaishali

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089
  8. Duan, James J.-W.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933

E

  1. Engst, Wolfram

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964

F

  1. Fenu, Luca A.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644
  2. Fisher, Craig D.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  3. Fluhler, Eric

    1. You have access
      Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species
      Huadong Tang, Azher Hussain, Mauricio Leal, Michael Mayersohn and Eric Fluhler
      Drug Metabolism and Disposition October 2007, 35 (10) 1886-1893; DOI: https://doi.org/10.1124/dmd.107.016188
  4. Fonsi, Massimiliano

    1. You have access
      High-Throughput Radiometric CYP2C19 Inhibition Assay Using Tritiated (S)-Mephenytoin
      Annalise Di Marco, Antonella Cellucci, Ashok Chaudhary, Massimiliano Fonsi and Ralph Laufer
      Drug Metabolism and Disposition October 2007, 35 (10) 1737-1743; DOI: https://doi.org/10.1124/dmd.107.016345
  5. Fossler, Michael J.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  6. Frank, Heinz

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  7. Freathy, C.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  8. Frei, Eva

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  9. Fujiwara, Ryoichi

    1. You have access
      Interactions between Human UGT1A1, UGT1A4, and UGT1A6 Affect Their Enzymatic Activities
      Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2007, 35 (10) 1781-1787; DOI: https://doi.org/10.1124/dmd.107.016402
  10. Fukami, Tatsuki

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568
  11. Fuwa, Masahiro

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832

G

  1. Garner, C. Edwin

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  2. Gilissen, Ron A. H. J.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644
  3. Glatt, Hansruedi

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  4. Goedken, Michael J.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  5. Gullstrand, Helena

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297

H

  1. Haraguchi, Koichi

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  2. Hariparsad, Niresh

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089
  3. Hatakeyama, Nobuyuki

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832
  4. Hattori, Masao

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  5. Higashi, Eriko

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568
  6. Hinai, Yudai

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  7. Hiratsuka, Masahiro

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  8. Hirota, Takashi

    1. You have access
      Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta
      Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
      Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
  9. Ho, S.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  10. Hodek, Petr

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  11. Hoshino, Kouichi

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  12. Hudeček, Jiří

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  13. Hussain, Azher

    1. You have access
      Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species
      Huadong Tang, Azher Hussain, Mauricio Leal, Michael Mayersohn and Eric Fluhler
      Drug Metabolism and Disposition October 2007, 35 (10) 1886-1893; DOI: https://doi.org/10.1124/dmd.107.016188

I

  1. Ikeda, Toshihiko

    1. You have access
      Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta
      Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
      Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
  2. Ikushiro, Shin-ichi

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  3. Imagawa, Kenichi

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  4. Inoue, Masaki

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568
  5. Ishikawa, Masaaki

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  6. Itoh, Kunio

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  7. Itoh, Masahiro

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568

J

  1. Jakowski, Amy B.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  2. Jinno, Hideto

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  3. Jones, A. E.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  4. Jones, B. C.

    1. You have access
      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743
  5. Joukhadar, C.

    1. You have access
      Does Linezolid Inhibit Its Own Metabolism?—Population Pharmacokinetics As a Tool to Explain the Observed Nonlinearity in Both Healthy Volunteers and Septic Patients
      N. Plock, C. Buerger, C. Joukhadar, S. Kljucar and C. Kloft
      Drug Metabolism and Disposition October 2007, 35 (10) 1816-1823; DOI: https://doi.org/10.1124/dmd.106.013755
  6. Jung, Da W.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545
  7. Jung, Young S.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545

K

  1. Kamatani, Naoyuki

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  2. Kaniwa, Nahoko

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  3. Kanno, Jun

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  4. Kato, Yoshihisa

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  5. Katoh, Miki

    1. You have access
      Interactions between Human UGT1A1, UGT1A4, and UGT1A6 Affect Their Enzymatic Activities
      Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2007, 35 (10) 1781-1787; DOI: https://doi.org/10.1124/dmd.107.016402
  6. Kim, Dong-Hyun

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 2A6 by Decursinol Angelate Isolated from Angelica Gigas
      Hye Hyun Yoo, Min Woo Lee, Young Choong Kim, Chul-Ho Yun and Dong-Hyun Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1759-1765; DOI: https://doi.org/10.1124/dmd.107.016584
  7. Kim, Su-Ryang

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  8. Kim, Su N.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545
  9. Kim, Young C.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545
  10. Kim, Young Choong

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 2A6 by Decursinol Angelate Isolated from Angelica Gigas
      Hye Hyun Yoo, Min Woo Lee, Young Choong Kim, Chul-Ho Yun and Dong-Hyun Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1759-1765; DOI: https://doi.org/10.1124/dmd.107.016584
  11. Kisor, David F.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261
  12. Kitajima, Kaori

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832
  13. Klaassen, Curtis D.

    1. You have access
      Importance of Hepatic Induction of Constitutive Androstane Receptor and Other Transcription Factors That Regulate Xenobiotic Metabolism and Transport
      Jay S. Petrick and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2007, 35 (10) 1806-1815; DOI: https://doi.org/10.1124/dmd.107.015974
  14. Kljucar, S.

    1. You have access
      Does Linezolid Inhibit Its Own Metabolism?—Population Pharmacokinetics As a Tool to Explain the Observed Nonlinearity in Both Healthy Volunteers and Septic Patients
      N. Plock, C. Buerger, C. Joukhadar, S. Kljucar and C. Kloft
      Drug Metabolism and Disposition October 2007, 35 (10) 1816-1823; DOI: https://doi.org/10.1124/dmd.106.013755
  15. Kloft, C.

    1. You have access
      Does Linezolid Inhibit Its Own Metabolism?—Population Pharmacokinetics As a Tool to Explain the Observed Nonlinearity in Both Healthy Volunteers and Septic Patients
      N. Plock, C. Buerger, C. Joukhadar, S. Kljucar and C. Kloft
      Drug Metabolism and Disposition October 2007, 35 (10) 1816-1823; DOI: https://doi.org/10.1124/dmd.106.013755
  16. Koga, Nobuyuki

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  17. Konno, Yumiko

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  18. Korn, Solange H.

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297
  19. Kotrbová, Věra

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  20. Kuester, R. K.

    1. You have access
      Prediction of Metabolic Clearance of Bisphenol A (4,4 ′-Dihydroxy-2,2-diphenylpropane) using Cryopreserved Human Hepatocytes
      R. K. Kuester and I. G. Sipes
      Drug Metabolism and Disposition October 2007, 35 (10) 1910-1915; DOI: https://doi.org/10.1124/dmd.107.014787
  21. Kusuhara, Hiroyuki

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  22. Kyo, Satoru

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568

L

  1. Laake, Janet

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  2. Laufer, Ralph

    1. You have access
      High-Throughput Radiometric CYP2C19 Inhibition Assay Using Tritiated (S)-Mephenytoin
      Annalise Di Marco, Antonella Cellucci, Ashok Chaudhary, Massimiliano Fonsi and Ralph Laufer
      Drug Metabolism and Disposition October 2007, 35 (10) 1737-1743; DOI: https://doi.org/10.1124/dmd.107.016345
  3. Lazarus, Philip

    1. You have access
      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  4. Leal, Mauricio

    1. You have access
      Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species
      Huadong Tang, Azher Hussain, Mauricio Leal, Michael Mayersohn and Eric Fluhler
      Drug Metabolism and Disposition October 2007, 35 (10) 1886-1893; DOI: https://doi.org/10.1124/dmd.107.016188
  5. Lee, Min Woo

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 2A6 by Decursinol Angelate Isolated from Angelica Gigas
      Hye Hyun Yoo, Min Woo Lee, Young Choong Kim, Chul-Ho Yun and Dong-Hyun Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1759-1765; DOI: https://doi.org/10.1124/dmd.107.016584
  6. Lee, Min Y.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545
  7. Lexmüller, Kristina

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297
  8. Li, Fang

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089
  9. Li, Feng

    1. You have access
      Metabolic Profile of [14C]Bendamustine in Rat Urine and Bile: Preliminary Structural Identification of Metabolites
      James P. Chovan, Feng Li, Erya Yu and Steven C. Ring
      Drug Metabolism and Disposition October 2007, 35 (10) 1744-1753; DOI: https://doi.org/10.1124/dmd.107.015958
  10. Lickteig, Andrew J.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  11. Lin, Jian

    1. You have access
      P-glycoprotein Has Differential Effects on the Disposition of Statin Acid and Lactone Forms in mdr1a/b Knockout and Wild-Type Mice
      Cuiping Chen, Jian Lin, Teresa Smolarek and Larry Tremaine
      Drug Metabolism and Disposition October 2007, 35 (10) 1725-1729; DOI: https://doi.org/10.1124/dmd.107.015677
  12. Lindsay, N.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  13. Liu, Rui-Qin

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  14. Lowdon, B. M.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966

M

  1. Mackie, Claire E.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644
  2. Maduskuie, Thomas

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  3. Manautou, Jose E.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  4. Manautou, José E.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  5. Manchee, G. R.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  6. Maruyama, Hiroaki

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  7. Matsumoto, Kenji

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  8. Mayersohn, Michael

    1. You have access
      Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species
      Huadong Tang, Azher Hussain, Mauricio Leal, Michael Mayersohn and Eric Fluhler
      Drug Metabolism and Disposition October 2007, 35 (10) 1886-1893; DOI: https://doi.org/10.1124/dmd.107.016188
  9. Merino, Gracia

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  10. Miller-Larsson, Anna

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297
  11. Minami, Hironobu

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  12. Miura, Shin-ichi

    1. You have access
      Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta
      Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
      Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
  13. Mizugaki, Michinao

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  14. Monien, Bernhard H.

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  15. Mrázová, Barbora

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  16. Murai, Takahiro

    1. You have access
      Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta
      Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
      Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121

N

  1. Nader, Michael A.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261
  2. Nakajima, Miki

    1. You have access
      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568
    2. You have access
      Interactions between Human UGT1A1, UGT1A4, and UGT1A6 Affect Their Enzymatic Activities
      Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2007, 35 (10) 1781-1787; DOI: https://doi.org/10.1124/dmd.107.016402
  3. Nakamura, Norio

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  4. Nemoto, Nobuo

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832
  5. Newton, Robert C.

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  6. Nichols, David E.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261
  7. Nijsen, Marjoleen J.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644

O

  1. Ohtsu, Atsushi

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  2. Oitate, Masataka

    1. You have access
      Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta
      Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
      Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
  3. Ozawa, Shogo

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339

P

  1. Perkins, Everett J.

    1. You have access
      Pharmacokinetics, Metabolism, and Excretion of the Intestinal Peptide Transporter 1 (SLC15A1)-Targeted Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2-Amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in Rats and Dogs: Assessment of First-Pass Bioactivation and Dose Linearity
      Everett J. Perkins and Trent Abraham
      Drug Metabolism and Disposition October 2007, 35 (10) 1903-1909; DOI: https://doi.org/10.1124/dmd.107.016154
  2. Perrett, H. F.

    1. You have access
      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743
  3. Peters, Stefan Oliver

    1. You have access
      Influence of Short-Term Use of Dexamethasone on the Pharmacokinetics of Ifosfamide in Patients
      Svenja Kristin Brüggemann, Sonja Pfäffle, Stefan Oliver Peters and Thomas Wagner
      Drug Metabolism and Disposition October 2007, 35 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.106.014043
  4. Petrick, Jay S.

    1. You have access
      Importance of Hepatic Induction of Constitutive Androstane Receptor and Other Transcription Factors That Regulate Xenobiotic Metabolism and Transport
      Jay S. Petrick and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2007, 35 (10) 1806-1815; DOI: https://doi.org/10.1124/dmd.107.015974
  5. Pfäffle, Sonja

    1. You have access
      Influence of Short-Term Use of Dexamethasone on the Pharmacokinetics of Ifosfamide in Patients
      Svenja Kristin Brüggemann, Sonja Pfäffle, Stefan Oliver Peters and Thomas Wagner
      Drug Metabolism and Disposition October 2007, 35 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.106.014043
  6. Plock, N.

    1. You have access
      Does Linezolid Inhibit Its Own Metabolism?—Population Pharmacokinetics As a Tool to Explain the Observed Nonlinearity in Both Healthy Volunteers and Septic Patients
      N. Plock, C. Buerger, C. Joukhadar, S. Kljucar and C. Kloft
      Drug Metabolism and Disposition October 2007, 35 (10) 1816-1823; DOI: https://doi.org/10.1124/dmd.106.013755
  7. Pruimboom-Brees, Ingrid M.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170

Q

  1. Qian, Mingxin

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933

R

  1. Ring, Steven C.

    1. You have access
      Metabolic Profile of [14C]Bendamustine in Rat Urine and Bile: Preliminary Structural Identification of Metabolites
      James P. Chovan, Feng Li, Erya Yu and Steven C. Ring
      Drug Metabolism and Disposition October 2007, 35 (10) 1744-1753; DOI: https://doi.org/10.1124/dmd.107.015958
  2. Rostami-Hodjegan, A.

    1. You have access
      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743

S

  1. Sai, Kimie

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  2. Saijo, Nagahiro

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  3. Saito, Hirohisa

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  4. Saito, Yoshiro

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  5. Sakaki, Toshiyuki

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  6. Sakuma, Tsutomu

    1. You have access
      Involvement of Glucocorticoid Receptor and Pregnane X Receptor in the Regulation of Mouse CYP3A44 Female-Predominant Expression by Glucocorticoid Hormone
      Wattanaporn Bhadhprasit, Tsutomu Sakuma, Nobuyuki Hatakeyama, Masahiro Fuwa, Kaori Kitajima and Nobuo Nemoto
      Drug Metabolism and Disposition October 2007, 35 (10) 1880-1885; DOI: https://doi.org/10.1124/dmd.107.016832
  7. Sasahara, Masakiyo

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  8. Sasaki, Takamitsu

    1. You have access
      Characterization of Human Cytochrome P450 Enzymes Involved in the Metabolism of Cilostazol
      Masahiro Hiratsuka, Yudai Hinai, Takamitsu Sasaki, Yumiko Konno, Kenichi Imagawa, Masaaki Ishikawa and Michinao Mizugaki
      Drug Metabolism and Disposition October 2007, 35 (10) 1730-1732; DOI: https://doi.org/10.1124/dmd.107.016758
  9. Sawada, Jun-ichi

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  10. Scheffer, George L.

    1. You have access
      Induction of Hepatobiliary Efflux Transporters in Acetaminophen-Induced Acute Liver Failure Cases
      Sarah N. Barnes, Lauren M. Aleksunes, Lisa Augustine, George L. Scheffer, Michael J. Goedken, Amy B. Jakowski, Ingrid M. Pruimboom-Brees, Nathan J. Cherrington and José E. Manautou
      Drug Metabolism and Disposition October 2007, 35 (10) 1963-1969; DOI: https://doi.org/10.1124/dmd.107.016170
  11. Schinkel, Alfred H.

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  12. Seidel, Albrecht

    1. You have access
      Directing Role of Organic Anion Transporters in the Excretion of Mercapturic Acids of Alkylated Polycyclic Aromatic Hydrocarbons
      Nadiya Bakhiya, Monika Batke, Janet Laake, Bernhard H. Monien, Heinz Frank, Albrecht Seidel, Wolfram Engst and Hansruedi Glatt
      Drug Metabolism and Disposition October 2007, 35 (10) 1824-1831; DOI: https://doi.org/10.1124/dmd.107.016964
  13. Seo, Ji Y.

    1. You have access
      Induction of Hepatic CYP2E1 by a Subtoxic Dose of Acetaminophen in Rats: Increase in Dichloromethane Metabolism and Carboxyhemoglobin Elevation
      Su N. Kim, Ji Y. Seo, Da W. Jung, Min Y. Lee, Young S. Jung and Young C. Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1754-1758; DOI: https://doi.org/10.1124/dmd.107.015545
  14. Sharma, Arun K.

    1. You have access
      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  15. Shirao, Kuniaki

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  16. Silberstein, David S.

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297
  17. Sinha, Vikash K.

    1. You have access
      Prediction of Human Pharmacokinetics Using Physiologically Based Modeling: A Retrospective Analysis of 26 Clinically Tested Drugs
      Stefan S. De Buck, Vikash K. Sinha, Luca A. Fenu, Marjoleen J. Nijsen, Claire E. Mackie and Ron A. H. J. Gilissen
      Drug Metabolism and Disposition October 2007, 35 (10) 1766-1780; DOI: https://doi.org/10.1124/dmd.107.015644
  18. Sipes, I. G.

    1. You have access
      Prediction of Metabolic Clearance of Bisphenol A (4,4 ′-Dihydroxy-2,2-diphenylpropane) using Cryopreserved Human Hepatocytes
      R. K. Kuester and I. G. Sipes
      Drug Metabolism and Disposition October 2007, 35 (10) 1910-1915; DOI: https://doi.org/10.1124/dmd.107.014787
  19. Sjölin, Petter

    1. You have access
      Differences in Endogenous Esterification and Retention in the Rat Trachea between Budesonide and Ciclesonide Active Metabolite
      Kristina Lexmüller, Helena Gullstrand, Bengt-Olof Axelsson, Petter Sjölin, Solange H. Korn, David S. Silberstein and Anna Miller-Larsson
      Drug Metabolism and Disposition October 2007, 35 (10) 1788-1796; DOI: https://doi.org/10.1124/dmd.107.015297
  20. Slitt, Angela L.

    1. You have access
      Efflux Transporter Expression and Acetaminophen Metabolite Excretion Are Altered in Rodent Models of Nonalcoholic Fatty Liver Disease
      Andrew J. Lickteig, Craig D. Fisher, Lisa M. Augustine, Lauren M. Aleksunes, David G. Besselsen, Angela L. Slitt, Jose E. Manautou and Nathan J. Cherrington
      Drug Metabolism and Disposition October 2007, 35 (10) 1970-1978; DOI: https://doi.org/10.1124/dmd.107.015107
  21. Smolarek, Teresa

    1. You have access
      P-glycoprotein Has Differential Effects on the Disposition of Statin Acid and Lactone Forms in mdr1a/b Knockout and Wild-Type Mice
      Cuiping Chen, Jian Lin, Teresa Smolarek and Larry Tremaine
      Drug Metabolism and Disposition October 2007, 35 (10) 1725-1729; DOI: https://doi.org/10.1124/dmd.107.015677
  22. Somers, G. I.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  23. Sprague, Jon E.

    1. You have access
      Ambient Temperature Effects on 3,4-Methylenedioxymethamphetamine-Induced Thermodysregulation and Pharmacokinetics in Male Monkeys
      Matthew L. Banks, Jon E. Sprague, David F. Kisor, Paul W. Czoty, David E. Nichols and Michael A. Nader
      Drug Metabolism and Disposition October 2007, 35 (10) 1840-1845; DOI: https://doi.org/10.1124/dmd.107.016261
  24. Stiborová, Marie

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  25. Sugiyama, Yuichi

    1. You have access
      Involvement of Breast Cancer Resistance Protein (ABCG2) in the Biliary Excretion Mechanism of Fluoroquinolones
      Tomohiro Ando, Hiroyuki Kusuhara, Gracia Merino, Ana I. Alvarez, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2007, 35 (10) 1873-1879; DOI: https://doi.org/10.1124/dmd.107.014969
  26. Sun, Dongxiao

    1. You have access
      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  27. Svobodová, Lucie

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048

T

  1. Takagawa, Kiyoshi

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  2. Takiguchi, Rie

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  3. Tanaka, Yorihisa

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  4. Tanaka-Kagawa, Toshiko

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  5. Tang, Huadong

    1. You have access
      Interspecies Prediction of Human Drug Clearance Based on Scaling Data from One or Two Animal Species
      Huadong Tang, Azher Hussain, Mauricio Leal, Michael Mayersohn and Eric Fluhler
      Drug Metabolism and Disposition October 2007, 35 (10) 1886-1893; DOI: https://doi.org/10.1124/dmd.107.016188
  6. Tang, Jun

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  7. Thummel, Kenneth E.

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089
  8. Tremaine, Larry

    1. You have access
      P-glycoprotein Has Differential Effects on the Disposition of Statin Acid and Lactone Forms in mdr1a/b Knockout and Wild-Type Mice
      Cuiping Chen, Jian Lin, Teresa Smolarek and Larry Tremaine
      Drug Metabolism and Disposition October 2007, 35 (10) 1725-1729; DOI: https://doi.org/10.1124/dmd.107.015677
  9. Trzaskos, James

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933
  10. Tucker, G. T.

    1. You have access
      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743

U

  1. Uchida, Shinya

    1. You have access
      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
  2. Unadkat, Jashvant D.

    1. You have access
      Cytochrome P450 Enzymes and Transporters Induced by Anti-Human Immunodeficiency Virus Protease Inhibitors in Human Hepatocytes: Implications for Predicting Clinical Drug Interactions
      Vaishali Dixit, Niresh Hariparsad, Fang Li, Pankaj Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition October 2007, 35 (10) 1853-1859; DOI: https://doi.org/10.1124/dmd.107.016089

V

  1. Václavíková, Radka

    1. You have access
      The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism
      Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Jiří Hudeček, Radka Václavíková, Eva Frei and Marie Stiborová
      Drug Metabolism and Disposition October 2007, 35 (10) 1926-1934; DOI: https://doi.org/10.1124/dmd.107.016048
  2. Vaddi, Kris

    1. You have access
      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
      Mingxin Qian, Stephen A. Bai, Bernice Brogdon, Jing-Tao Wu, Rui-Qin Liu, Maryanne B. Covington, Kris Vaddi, Robert C. Newton, Michael J. Fossler, C. Edwin Garner, Yuzhong Deng, Thomas Maduskuie, James Trzaskos, James J.-W. Duan, Carl P. Decicco and David D. Christ
      Drug Metabolism and Disposition October 2007, 35 (10) 1916-1925; DOI: https://doi.org/10.1124/dmd.107.015933

W

  1. Wagner, Thomas

    1. You have access
      Influence of Short-Term Use of Dexamethasone on the Pharmacokinetics of Ifosfamide in Patients
      Svenja Kristin Brüggemann, Sonja Pfäffle, Stefan Oliver Peters and Thomas Wagner
      Drug Metabolism and Disposition October 2007, 35 (10) 1721-1724; DOI: https://doi.org/10.1124/dmd.106.014043
  2. Wang, Joanne

    1. You have access
      Metformin Transport by a Newly Cloned Proton-Stimulated Organic Cation Transporter (Plasma Membrane Monoamine Transporter) Expressed in Human Intestine
      Mingyan Zhou, Li Xia and Joanne Wang
      Drug Metabolism and Disposition October 2007, 35 (10) 1956-1962; DOI: https://doi.org/10.1124/dmd.107.015495
  3. Wang, Zheng-Tao

    1. You have access
      In Vitro Metabolism of Isoline, a Pyrrolizidine Alkaloid from Ligularia duciformis, by Rodent Liver Microsomal Esterase and Enhanced Hepatotoxicity by Esterase Inhibitors
      Jun Tang, Teruaki Akao, Norio Nakamura, Zheng-Tao Wang, Kiyoshi Takagawa, Masakiyo Sasahara and Masao Hattori
      Drug Metabolism and Disposition October 2007, 35 (10) 1832-1839; DOI: https://doi.org/10.1124/dmd.107.016311
  4. Watanabe, Nobuaki

    1. You have access
      Lack of Formation of Aldehyde Oxidase Dimer Possibly Due to 377G>A Nucleotide Substitution
      Kunio Itoh, Hiroaki Maruyama, Mayuko Adachi, Kouichi Hoshino, Nobuaki Watanabe and Yorihisa Tanaka
      Drug Metabolism and Disposition October 2007, 35 (10) 1860-1864; DOI: https://doi.org/10.1124/dmd.107.015503
  5. Woodrooffe, A. J. M.

    1. You have access
      A Comparison of the Expression and Metabolizing Activities of Phase I and II Enzymes in Freshly Isolated Human Lung Parenchymal Cells and Cryopreserved Human Hepatocytes
      G. I. Somers, N. Lindsay, B. M. Lowdon, A. E. Jones, C. Freathy, S. Ho, A. J. M. Woodrooffe, M. K. Bayliss and G. R. Manchee
      Drug Metabolism and Disposition October 2007, 35 (10) 1797-1805; DOI: https://doi.org/10.1124/dmd.107.015966
  6. Wright, Jason

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      In Vitro Prediction and in Vivo Verification of Enantioselective Human Tofisopam Metabolite Profiles
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      Drug Metabolism and Disposition October 2007, 35 (10) 1894-1902; DOI: https://doi.org/10.1124/dmd.107.015875
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      Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans
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X

  1. Xia, Li

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      Metformin Transport by a Newly Cloned Proton-Stimulated Organic Cation Transporter (Plasma Membrane Monoamine Transporter) Expressed in Human Intestine
      Mingyan Zhou, Li Xia and Joanne Wang
      Drug Metabolism and Disposition October 2007, 35 (10) 1956-1962; DOI: https://doi.org/10.1124/dmd.107.015495

Y

  1. Yamada, Shizuo

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      A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats
      Yoshihisa Kato, Shin-ichi Ikushiro, Rie Takiguchi, Koichi Haraguchi, Nobuyuki Koga, Shinya Uchida, Toshiyuki Sakaki, Shizuo Yamada, Jun Kanno and Masakuni Degawa
      Drug Metabolism and Disposition October 2007, 35 (10) 1949-1955; DOI: https://doi.org/10.1124/dmd.107.017327
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      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  3. Yamanaka, Hiroyuki

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      Interactions between Human UGT1A1, UGT1A4, and UGT1A6 Affect Their Enzymatic Activities
      Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2007, 35 (10) 1781-1787; DOI: https://doi.org/10.1124/dmd.107.016402
  4. Yamazaki, H.

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      Disparity in Holoprotein/Apoprotein Ratios of Different Standards Used for Immunoquantification of Hepatic Cytochrome P450 Enzymes
      H. F. Perrett, Z. E. Barter, B. C. Jones, H. Yamazaki, G. T. Tucker and A. Rostami-Hodjegan
      Drug Metabolism and Disposition October 2007, 35 (10) 1733-1736; DOI: https://doi.org/10.1124/dmd.107.015743
  5. Ye, Naidong

    1. You have access
      In Vitro Prediction and in Vivo Verification of Enantioselective Human Tofisopam Metabolite Profiles
      Michael D. Cameron, Jason Wright, Christopher B. Black and Naidong Ye
      Drug Metabolism and Disposition October 2007, 35 (10) 1894-1902; DOI: https://doi.org/10.1124/dmd.107.015875
  6. Yokoi, Tsuyoshi

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      Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
      Eriko Higashi, Tatsuki Fukami, Masahiro Itoh, Satoru Kyo, Masaki Inoue, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition October 2007, 35 (10) 1935-1941; DOI: https://doi.org/10.1124/dmd.107.016568
    2. You have access
      Interactions between Human UGT1A1, UGT1A4, and UGT1A6 Affect Their Enzymatic Activities
      Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition October 2007, 35 (10) 1781-1787; DOI: https://doi.org/10.1124/dmd.107.016402
  7. Yoo, Hye Hyun

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      Mechanism-Based Inactivation of Cytochrome P450 2A6 by Decursinol Angelate Isolated from Angelica Gigas
      Hye Hyun Yoo, Min Woo Lee, Young Choong Kim, Chul-Ho Yun and Dong-Hyun Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1759-1765; DOI: https://doi.org/10.1124/dmd.107.016584
  8. Yoshida, Teruhiko

    1. You have access
      Haplotypes and a Novel Defective Allele of CES2 Found in a Japanese Population
      Su-Ryang Kim, Kimie Sai, Toshiko Tanaka-Kagawa, Hideto Jinno, Shogo Ozawa, Nahoko Kaniwa, Yoshiro Saito, Akira Akasawa, Kenji Matsumoto, Hirohisa Saito, Naoyuki Kamatani, Kuniaki Shirao, Noboru Yamamoto, Teruhiko Yoshida, Hironobu Minami, Atsushi Ohtsu, Nagahiro Saijo and Jun-ichi Sawada
      Drug Metabolism and Disposition October 2007, 35 (10) 1865-1872; DOI: https://doi.org/10.1124/dmd.107.015339
  9. Yu, Erya

    1. You have access
      Metabolic Profile of [14C]Bendamustine in Rat Urine and Bile: Preliminary Structural Identification of Metabolites
      James P. Chovan, Feng Li, Erya Yu and Steven C. Ring
      Drug Metabolism and Disposition October 2007, 35 (10) 1744-1753; DOI: https://doi.org/10.1124/dmd.107.015958
  10. Yun, Chul-Ho

    1. You have access
      Mechanism-Based Inactivation of Cytochrome P450 2A6 by Decursinol Angelate Isolated from Angelica Gigas
      Hye Hyun Yoo, Min Woo Lee, Young Choong Kim, Chul-Ho Yun and Dong-Hyun Kim
      Drug Metabolism and Disposition October 2007, 35 (10) 1759-1765; DOI: https://doi.org/10.1124/dmd.107.016584

Z

  1. Zheng, Yan

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      Elimination of Antiestrogenic Effects of Active Tamoxifen Metabolites by Glucuronidation
      Yan Zheng, Dongxiao Sun, Arun K. Sharma, Gang Chen, Shantu Amin and Philip Lazarus
      Drug Metabolism and Disposition October 2007, 35 (10) 1942-1948; DOI: https://doi.org/10.1124/dmd.107.016279
  2. Zhou, Mingyan

    1. You have access
      Metformin Transport by a Newly Cloned Proton-Stimulated Organic Cation Transporter (Plasma Membrane Monoamine Transporter) Expressed in Human Intestine
      Mingyan Zhou, Li Xia and Joanne Wang
      Drug Metabolism and Disposition October 2007, 35 (10) 1956-1962; DOI: https://doi.org/10.1124/dmd.107.015495
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Drug Metabolism and Disposition: 35 (10)
Drug Metabolism and Disposition
Vol. 35, Issue 10
1 Oct 2007
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