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Research ArticleArticle

Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta

Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
Drug Metabolism and Disposition October 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
Masataka Oitate
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Takashi Hirota
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Takahiro Murai
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Shin-ichi Miura
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Toshihiko Ikeda
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Article Information

vol. 35 no. 10 1846-1852
DOI 
https://doi.org/10.1124/dmd.107.016121
PubMed 
17620346

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 12, 2007
  • Accepted July 6, 2007
  • Published online September 24, 2007.

Article Versions

  • Earlier version (July 9, 2007 - 09:14).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Masataka Oitate,
  2. Takashi Hirota,
  3. Takahiro Murai,
  4. Shin-ichi Miura and
  5. Toshihiko Ikeda
  1. Drug Metabolism & Pharmacokinetics Research Laboratories (M.O., T.M., S.M., T.I.), and Global Project Management Department (T.H.), Daiichi Sankyo Co., Ltd., Tokyo, Japan
  1. Address correspondence to:
    Masataka Oitate, Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan. E-mail: oitate.masataka.i3{at}daiichisankyo.co.jp
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Drug Metabolism and Disposition: 35 (10)
Drug Metabolism and Disposition
Vol. 35, Issue 10
1 Oct 2007
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Research ArticleArticle

Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta

Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
Drug Metabolism and Disposition October 1, 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121

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Research ArticleArticle

Covalent Binding of Rofecoxib, but Not Other Cyclooxygenase-2 Inhibitors, to Allysine Aldehyde in Elastin of Human Aorta

Masataka Oitate, Takashi Hirota, Takahiro Murai, Shin-ichi Miura and Toshihiko Ikeda
Drug Metabolism and Disposition October 1, 2007, 35 (10) 1846-1852; DOI: https://doi.org/10.1124/dmd.107.016121
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