Advertisement
Research ArticleArticle

Pharmacokinetics, Metabolism, and Excretion of the Intestinal Peptide Transporter 1 (SLC15A1)-Targeted Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2-Amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in Rats and Dogs: Assessment of First-Pass Bioactivation and Dose Linearity

Everett J. Perkins and Trent Abraham
Drug Metabolism and Disposition October 2007, 35 (10) 1903-1909; DOI: https://doi.org/10.1124/dmd.107.016154

Article Information

vol. 35 no. 10 1903-1909
DOI 
https://doi.org/10.1124/dmd.107.016154
PubMed 
17646281
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 6, 2007
  • Accepted July 19, 2007
  • Published online September 24, 2007.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Everett J. Perkins and
  2. Trent Abraham
  1. Lilly Research Laboratories, Indianapolis, Indiana
  1. Address correspondence to:
    Dr. Everett J. Perkins, Lilly Corporate Center, Indianapolis, IN 46285. E-mail: perkins.e{at}Lilly.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to January 2023

AbstractFullPdf
Aug 20173227
Sep 2017253
Oct 20172316
Nov 201724914
Dec 20170176
Jan 20182164
Feb 201822411
Mar 20183228
Apr 20183216
May 20180266
Jun 20181143
Jul 20181108
Aug 20180195
Sep 20183148
Oct 20180148
Nov 201801315
Dec 20181284
Jan 20191207
Feb 20191514
Mar 2019613
Apr 20191016
May 2019903
Jun 20191419
Jul 20192204
Aug 20192046
Oct 20191211
Nov 20191600
Dec 20191213
Jan 20201201
Feb 20201400
Mar 20201323
May 2020812
Jun 20201610
Jul 2020500
Aug 2020003
Sep 20201100
Oct 2020801
Nov 20201005
Dec 20201815
Jan 20212032
Feb 20212239
Mar 20211963
Apr 20211213
May 20211031
Jun 2021834
Jul 20211013
Aug 2021421
Sep 20211021
Oct 2021911
Nov 20211413
Dec 20212834
Jan 2022410
Feb 20221022
Mar 20221814
Apr 20221242
May 2022921
Jun 20221823
Jul 202211310
Aug 20223822
Sep 20223911
Oct 20224019
Nov 20224022
Dec 20222914
Jan 20234863

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

Pharmacokinetics, Metabolism, and Excretion of the Intestinal Peptide Transporter 1 (SLC15A1)-Targeted Prodrug (1S,2S,5R,6S)-2-[(2′S)-(2-Amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in Rats and Dogs: Assessment of First-Pass Bioactivation and Dose Linearity

Everett J. Perkins and Trent Abraham
Drug Metabolism and Disposition October 1, 2007, 35 (10) 1903-1909; DOI: https://doi.org/10.1124/dmd.107.016154
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo

Jump to section

Advertisement