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Research ArticleArticle

Functional Induction of P-glycoprotein in the Blood-Brain Barrier of Streptozotocin-Induced Diabetic Rats: Evidence for the Involvement of Nuclear Factor-κB, a Nitrosative Stress-Sensitive Transcription Factor, in the Regulation

Han-Joo Maeng, Mi-Hwa Kim, Hyo-Eon Jin, Sang Mi Shin, Takasi Tsuruo, Sang Geon Kim, Dae-Duk Kim, Chang-Koo Shim and Suk-Jae Chung
Drug Metabolism and Disposition November 2007, 35 (11) 1996-2005; DOI: https://doi.org/10.1124/dmd.107.015800

Article Information

vol. 35 no. 11 1996-2005
DOI 
https://doi.org/10.1124/dmd.107.015800
PubMed 
17664251
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 21, 2007
  • Accepted July 25, 2007
  • Published online October 18, 2007.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Han-Joo Maeng,
  2. Mi-Hwa Kim,
  3. Hyo-Eon Jin,
  4. Sang Mi Shin,
  5. Takasi Tsuruo,
  6. Sang Geon Kim,
  7. Dae-Duk Kim,
  8. Chang-Koo Shim and
  9. Suk-Jae Chung
  1. Department of Pharmaceutics, College of Pharmacy (H.-J.M., M.-H.K., H.-E.J., D.-D.K., C.-K.S., S.-J.C.), and National Research Laboratory, College of Pharmacy and Research Institute of Pharmaceutical Sciences (S.M.S., S.G.K.), Seoul National University, Seoul, Korea; and Graduate School of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan (T.T.)
  1. Address correspondence to:
    Dr. Suk-Jae Chung, Department of Pharmaceutics, College of Pharmacy, Seoul National University, San 56-1 Shinlim-dong, Kwanak-gu, Seoul 151-742, Korea. E-mail: sukjae{at}plaza.snu.ac.kr
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Research ArticleArticle

Functional Induction of P-glycoprotein in the Blood-Brain Barrier of Streptozotocin-Induced Diabetic Rats: Evidence for the Involvement of Nuclear Factor-κB, a Nitrosative Stress-Sensitive Transcription Factor, in the Regulation

Han-Joo Maeng, Mi-Hwa Kim, Hyo-Eon Jin, Sang Mi Shin, Takasi Tsuruo, Sang Geon Kim, Dae-Duk Kim, Chang-Koo Shim and Suk-Jae Chung
Drug Metabolism and Disposition November 1, 2007, 35 (11) 1996-2005; DOI: https://doi.org/10.1124/dmd.107.015800
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