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Research ArticleArticle

A Comparison of 2-Phenyl-2-(1-piperidinyl)propane (PPP), 1,1′,1″-Phosphinothioylidynetrisaziridine (ThioTEPA), Clopidogrel, and Ticlopidine as Selective Inactivators of Human Cytochrome P450 2B6

Robert L. Walsky and R. Scott Obach
Drug Metabolism and Disposition November 2007, 35 (11) 2053-2059; DOI: https://doi.org/10.1124/dmd.107.015883

Article Information

vol. 35 no. 11 2053-2059
DOI 
https://doi.org/10.1124/dmd.107.015883
PubMed 
17682072
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 22, 2007
  • Accepted August 3, 2007
  • Published online October 18, 2007.

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The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Robert L. Walsky and
  2. R. Scott Obach
  1. Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer, Inc., Groton, Connecticut
  1. Address correspondence to:
    R. Scott Obach, Pfizer, Inc., Groton, CT 06340. E-mail: r.scott.obach{at}pfizer.com
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Research ArticleArticle

A Comparison of 2-Phenyl-2-(1-piperidinyl)propane (PPP), 1,1′,1″-Phosphinothioylidynetrisaziridine (ThioTEPA), Clopidogrel, and Ticlopidine as Selective Inactivators of Human Cytochrome P450 2B6

Robert L. Walsky and R. Scott Obach
Drug Metabolism and Disposition November 1, 2007, 35 (11) 2053-2059; DOI: https://doi.org/10.1124/dmd.107.015883
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