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Research ArticleArticle

Use of Isolated Hepatocyte Preparations for Cytochrome P450 Inhibition Studies: Comparison with Microsomes for Ki Determination

Hayley S. Brown, Anthony Chadwick and J. Brian Houston
Drug Metabolism and Disposition November 2007, 35 (11) 2119-2126; DOI: https://doi.org/10.1124/dmd.107.017095
Hayley S. Brown
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Anthony Chadwick
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J. Brian Houston
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Article Information

vol. 35 no. 11 2119-2126
DOI 
https://doi.org/10.1124/dmd.107.017095
PubMed 
17724064

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 8, 2007
  • Accepted August 24, 2007
  • Published online October 18, 2007.

Article Versions

  • Earlier version (August 27, 2007 - 07:17).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hayley S. Brown,
  2. Anthony Chadwick1 and
  3. J. Brian Houston
  1. Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
  1. Address correspondence to:
    J. Brian Houston, Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, M13 9PT, UK. E-mail: brian.houston{at}manchester.ac.uk
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Drug Metabolism and Disposition: 35 (11)
Drug Metabolism and Disposition
Vol. 35, Issue 11
1 Nov 2007
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Research ArticleArticle

Use of Isolated Hepatocyte Preparations for Cytochrome P450 Inhibition Studies: Comparison with Microsomes for Ki Determination

Hayley S. Brown, Anthony Chadwick and J. Brian Houston
Drug Metabolism and Disposition November 1, 2007, 35 (11) 2119-2126; DOI: https://doi.org/10.1124/dmd.107.017095

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Research ArticleArticle

Use of Isolated Hepatocyte Preparations for Cytochrome P450 Inhibition Studies: Comparison with Microsomes for Ki Determination

Hayley S. Brown, Anthony Chadwick and J. Brian Houston
Drug Metabolism and Disposition November 1, 2007, 35 (11) 2119-2126; DOI: https://doi.org/10.1124/dmd.107.017095
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