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Research ArticleArticle

Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions

R. Scott Obach, Robert L. Walsky and Karthik Venkatakrishnan
Drug Metabolism and Disposition February 2007, 35 (2) 246-255; DOI: https://doi.org/10.1124/dmd.106.012633
R. Scott Obach
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Robert L. Walsky
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Karthik Venkatakrishnan
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Article Information

vol. 35 no. 2 246-255
DOI 
https://doi.org/10.1124/dmd.106.012633
PubMed 
17093004

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 30, 2006
  • Accepted November 2, 2006
  • Published online January 23, 2007.

Article Versions

  • Earlier version (November 8, 2006 - 07:49).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. R. Scott Obach,
  2. Robert L. Walsky and
  3. Karthik Venkatakrishnan
  1. Pharmacokinetics, Dynamics, and Drug Metabolism (R.S.O., R.L.W.) and Clinical Pharmacology (K.V.), Pfizer, Inc., Groton, Connecticut
  1. Address correspondence to:
    R. Scott Obach, Pfizer Global Research and Development, Groton Labs, Groton, CT 06340. E-mail: r.scott.obach{at}pfizer.com
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Drug Metabolism and Disposition: 35 (2)
Drug Metabolism and Disposition
Vol. 35, Issue 2
1 Feb 2007
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Research ArticleArticle

Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions

R. Scott Obach, Robert L. Walsky and Karthik Venkatakrishnan
Drug Metabolism and Disposition February 1, 2007, 35 (2) 246-255; DOI: https://doi.org/10.1124/dmd.106.012633

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Research ArticleArticle

Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions

R. Scott Obach, Robert L. Walsky and Karthik Venkatakrishnan
Drug Metabolism and Disposition February 1, 2007, 35 (2) 246-255; DOI: https://doi.org/10.1124/dmd.106.012633
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