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Research ArticleArticle

Evaluation of Cryopreserved Human Hepatocytes as an Alternative in Vitro System to Microsomes for the Prediction of Metabolic Clearance

Hayley S. Brown, Michael Griffin and J. Brian Houston
Drug Metabolism and Disposition February 2007, 35 (2) 293-301; DOI: https://doi.org/10.1124/dmd.106.011569

Article Information

vol. 35 no. 2 293-301
DOI 
https://doi.org/10.1124/dmd.106.011569
PubMed 
17132764
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 21, 2006
  • Accepted November 17, 2006
  • Published online January 23, 2007.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hayley S. Brown,
  2. Michael Griffin and
  3. J. Brian Houston
  1. Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
  1. Address correspondence to:
    J. Brian Houston, Centre for Applied Pharmacokinetic Research, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, M13 9PL, UK. E-mail: brian.houston{at}manchester.ac.uk
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Research ArticleArticle

Evaluation of Cryopreserved Human Hepatocytes as an Alternative in Vitro System to Microsomes for the Prediction of Metabolic Clearance

Hayley S. Brown, Michael Griffin and J. Brian Houston
Drug Metabolism and Disposition February 1, 2007, 35 (2) 293-301; DOI: https://doi.org/10.1124/dmd.106.011569
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