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Index by author

March 01, 2007; Volume 35,Issue 3

A

  1. Ali, Shazia Y.

    1. UDP-Glucuronosyltransferase 1A1 Is the Principal Enzyme Responsible for Etoposide Glucuronidation in Human Liver and Intestinal Microsomes: Structural Characterization of Phenolic and Alcoholic Glucuronides of Etoposide and Estimation of Enzyme Kinetics
      Zhiming Wen, Melanie N. Tallman, Shazia Y. Ali and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 371-380; DOI: https://doi.org/10.1124/dmd.106.012732

  2. Argikar, Upendra

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  3. Ariyoshi, Noritaka

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  4. Arkan, Melek C.

    1. Differential Regulation of Hepatic Transporters in the Absence of Tumor Necrosis Factor-α, Interleukin-1β, Interleukin-6, and Nuclear Factor-κB in Two Models of Cholestasis
      Andrew J. Lickteig, Angela L. Slitt, Melek C. Arkan, Michael Karin and Nathan J. Cherrington
      Drug Metabolism and Disposition March 2007, 35 (3) 402-409; DOI: https://doi.org/10.1124/dmd.106.012138

  5. Auerbach, Scott S.

    1. CAR2 Displays Unique Ligand Binding and RXRα Heterodimerization Characteristics
      Scott S. Auerbach, Joshua G. DeKeyser, Matthew A. Stoner and Curtis J. Omiecinski
      Drug Metabolism and Disposition March 2007, 35 (3) 428-439; DOI: https://doi.org/10.1124/dmd.106.012641

B

  1. Ban, Masaaki

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

  2. Barbier, Olivier

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  3. Bonzo, Jessica A.

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  4. Bowalgaha, K.

    1. The Glucuronidation of Δ4-3-Keto C19- and C21-Hydroxysteroids by Human Liver Microsomal and Recombinant UDP-glucuronosyltransferases (UGTs): 6α- and 21-Hydroxyprogesterone Are Selective Substrates for UGT2B7
      K. Bowalgaha, D. J. Elliot, P. I. Mackenzie, K. M. Knights and J. O. Miners
      Drug Metabolism and Disposition March 2007, 35 (3) 363-370; DOI: https://doi.org/10.1124/dmd.106.013052

  5. Brace-Sinnokrak, Erin

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  6. Bridges, Arlene S.

    1. In Vitro and in Vivo Determination of Piperacillin Metabolism in Humans
      Giulia Ghibellini, Arlene S. Bridges, Claudia N. Generaux and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2007, 35 (3) 345-349; DOI: https://doi.org/10.1124/dmd.106.012278

  7. Brouwer, Kim L. R.

    1. In Vitro and in Vivo Determination of Piperacillin Metabolism in Humans
      Giulia Ghibellini, Arlene S. Bridges, Claudia N. Generaux and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2007, 35 (3) 345-349; DOI: https://doi.org/10.1124/dmd.106.012278

  8. Bullock, Peter

    1. Glucuronidation of Anti-HIV Drug Candidate Bevirimat: Identification of Human UDP-glucuronosyltransferases and Species Differences
      Zhiming Wen, David E. Martin, Peter Bullock, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 440-448; DOI: https://doi.org/10.1124/dmd.106.012815

C

  1. Cashman, John R.

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

  2. Chen, Shujuan

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  3. Cherrington, Nathan J.

    1. Differential Regulation of Hepatic Transporters in the Absence of Tumor Necrosis Factor-α, Interleukin-1β, Interleukin-6, and Nuclear Factor-κB in Two Models of Cholestasis
      Andrew J. Lickteig, Angela L. Slitt, Melek C. Arkan, Michael Karin and Nathan J. Cherrington
      Drug Metabolism and Disposition March 2007, 35 (3) 402-409; DOI: https://doi.org/10.1124/dmd.106.012138

  4. Courtney, Paul

    1. The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
      Charles J. O'Donnell, Ken Grime, Paul Courtney, Dean Slee and Robert J. Riley
      Drug Metabolism and Disposition March 2007, 35 (3) 381-385; DOI: https://doi.org/10.1124/dmd.106.012344

D

  1. DeKeyser, Joshua G.

    1. CAR2 Displays Unique Ligand Binding and RXRα Heterodimerization Characteristics
      Scott S. Auerbach, Joshua G. DeKeyser, Matthew A. Stoner and Curtis J. Omiecinski
      Drug Metabolism and Disposition March 2007, 35 (3) 428-439; DOI: https://doi.org/10.1124/dmd.106.012641

  2. Djebli, Nassim

    1. Metabolism of Sirolimus in the Presence or Absence of Cyclosporine by Genotyped Human Liver Microsomes and Recombinant Cytochromes P450 3A4 and 3A5
      Nicolas Picard, Nassim Djebli, François-Ludovic Sauvage and Pierre Marquet
      Drug Metabolism and Disposition March 2007, 35 (3) 350-355; DOI: https://doi.org/10.1124/dmd.106.012161

  3. Dupuis, Robert E.

    1. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

E

  1. Ekins, Sean

    1. Classification of Metabolites with Kernel-Partial Least Squares (K-PLS)
      Mark J. Embrechts and Sean Ekins
      Drug Metabolism and Disposition March 2007, 35 (3) 325-327; DOI: https://doi.org/10.1124/dmd.106.013185
    2. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

  2. Elliot, D. J.

    1. The Glucuronidation of Δ4-3-Keto C19- and C21-Hydroxysteroids by Human Liver Microsomal and Recombinant UDP-glucuronosyltransferases (UGTs): 6α- and 21-Hydroxyprogesterone Are Selective Substrates for UGT2B7
      K. Bowalgaha, D. J. Elliot, P. I. Mackenzie, K. M. Knights and J. O. Miners
      Drug Metabolism and Disposition March 2007, 35 (3) 363-370; DOI: https://doi.org/10.1124/dmd.106.013052

  3. Embrechts, Mark J.

    1. Classification of Metabolites with Kernel-Partial Least Squares (K-PLS)
      Mark J. Embrechts and Sean Ekins
      Drug Metabolism and Disposition March 2007, 35 (3) 325-327; DOI: https://doi.org/10.1124/dmd.106.013185

  4. Endo, Takuro

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

F

  1. Fukami, Tatsuki

    1. CYP2A13 Metabolizes the Substrates of Human CYP1A2, Phenacetin, and Theophylline
      Tatsuki Fukami, Miki Nakajima, Haruko Sakai, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition March 2007, 35 (3) 335-339; DOI: https://doi.org/10.1124/dmd.106.011064

G

  1. Gaus, Hans J.

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  2. Geary, Richard S.

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  3. Generaux, Claudia N.

    1. In Vitro and in Vivo Determination of Piperacillin Metabolism in Humans
      Giulia Ghibellini, Arlene S. Bridges, Claudia N. Generaux and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2007, 35 (3) 345-349; DOI: https://doi.org/10.1124/dmd.106.012278

  4. Ghibellini, Giulia

    1. In Vitro and in Vivo Determination of Piperacillin Metabolism in Humans
      Giulia Ghibellini, Arlene S. Bridges, Claudia N. Generaux and Kim L. R. Brouwer
      Drug Metabolism and Disposition March 2007, 35 (3) 345-349; DOI: https://doi.org/10.1124/dmd.106.012278

  5. Grime, Ken

    1. The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
      Charles J. O'Donnell, Ken Grime, Paul Courtney, Dean Slee and Robert J. Riley
      Drug Metabolism and Disposition March 2007, 35 (3) 381-385; DOI: https://doi.org/10.1124/dmd.106.012344

H

  1. Haefeli, Walter Emil

    1. Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by Nucleoside, Nucleotide, and Non-Nucleoside Reverse Transcriptase Inhibitors
      Johanna Weiss, Dirk Theile, Nahal Ketabi-Kiyanvash, Heike Lindenmaier and Walter Emil Haefeli
      Drug Metabolism and Disposition March 2007, 35 (3) 340-344; DOI: https://doi.org/10.1124/dmd.106.012765

  2. Hara, Yoshiki

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

  3. Harwood, H. James

    1. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

  4. Hata, Masayuki

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  5. Hayashi, Yujiro

    1. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

  6. Hirata, Kazuma

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

  7. Hirayama, Masamichi

    1. Mechanism of the Regulation of Organic Cation/Carnitine Transporter 1 (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines
      Tomoji Maeda, Masamichi Hirayama, Daisuke Kobayashi, Keiji Miyazawa and Ikumi Tamai
      Drug Metabolism and Disposition March 2007, 35 (3) 394-401; DOI: https://doi.org/10.1124/dmd.106.012112

  8. Hong, An

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  9. Hoover, Dennis J.

    1. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

I

  1. Ishii, Itsuko

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

J

  1. Jamei, Masoud

    1. Misuse of the Well-Stirred Model of Hepatic Drug Clearance
      Jiansong Yang, Masoud Jamei, Karen R. Yeo, Amin Rostami-Hodjegan and Geoffrey T. Tucker
      Drug Metabolism and Disposition March 2007, 35 (3) 501-502; DOI: https://doi.org/10.1124/dmd.106.013359

  2. Jie, Lu

    1. Inhibitory Effects of Benzoate on Chiral Inversion and Clearance of NG-Nitro-Arginine in Conscious Rats
      Xin Yan-Fei, Zhou Xiang-Jun, Lu Jie and Wang Yong-Xiang
      Drug Metabolism and Disposition March 2007, 35 (3) 331-334; DOI: https://doi.org/10.1124/dmd.106.011429

K

  1. Kaeding, Jenny

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  2. Kalvass, J. Cory

    1. Pharmacokinetics and Pharmacodynamics of Alfentanil in P-Glycoprotein-Competent and P-Glycoprotein-Deficient Mice: P-Glycoprotein Efflux Alters Alfentanil Brain Disposition and Antinociception
      J. Cory Kalvass, Emily R. Olson and Gary M. Pollack
      Drug Metabolism and Disposition March 2007, 35 (3) 455-459; DOI: https://doi.org/10.1124/dmd.106.011445

  3. Karin, Michael

    1. Differential Regulation of Hepatic Transporters in the Absence of Tumor Necrosis Factor-α, Interleukin-1β, Interleukin-6, and Nuclear Factor-κB in Two Models of Cholestasis
      Andrew J. Lickteig, Angela L. Slitt, Melek C. Arkan, Michael Karin and Nathan J. Cherrington
      Drug Metabolism and Disposition March 2007, 35 (3) 402-409; DOI: https://doi.org/10.1124/dmd.106.012138

  4. Kato, Yukio

    1. Functional Expression of Stereoselective Metabolism of Cephalexin by Exogenous Transfection of Oligopeptide Transporter PEPT1
      Keisuke Mitsuoka, Yukio Kato, Yoshiyuki Kubo and Akira Tsuji
      Drug Metabolism and Disposition March 2007, 35 (3) 356-362; DOI: https://doi.org/10.1124/dmd.106.010405
    2. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

  5. Katoh, Miki

    1. CYP2A13 Metabolizes the Substrates of Human CYP1A2, Phenacetin, and Theophylline
      Tatsuki Fukami, Miki Nakajima, Haruko Sakai, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition March 2007, 35 (3) 335-339; DOI: https://doi.org/10.1124/dmd.106.011064

  6. Kazama, Emiko

    1. Effect of Oral Ketoconazole on Intestinal First-Pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys
      Akihito Ogasawara, Toshiyuki Kume and Emiko Kazama
      Drug Metabolism and Disposition March 2007, 35 (3) 410-418; DOI: https://doi.org/10.1124/dmd.106.011288

  7. Ketabi-Kiyanvash, Nahal

    1. Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by Nucleoside, Nucleotide, and Non-Nucleoside Reverse Transcriptase Inhibitors
      Johanna Weiss, Dirk Theile, Nahal Ketabi-Kiyanvash, Heike Lindenmaier and Walter Emil Haefeli
      Drug Metabolism and Disposition March 2007, 35 (3) 340-344; DOI: https://doi.org/10.1124/dmd.106.012765

  8. Kim, Tae-Won

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  9. Kitada, Mitsukazu

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  10. Knights, K. M.

    1. The Glucuronidation of Δ4-3-Keto C19- and C21-Hydroxysteroids by Human Liver Microsomal and Recombinant UDP-glucuronosyltransferases (UGTs): 6α- and 21-Hydroxyprogesterone Are Selective Substrates for UGT2B7
      K. Bowalgaha, D. J. Elliot, P. I. Mackenzie, K. M. Knights and J. O. Miners
      Drug Metabolism and Disposition March 2007, 35 (3) 363-370; DOI: https://doi.org/10.1124/dmd.106.013052

  11. Kobayashi, Daisuke

    1. Mechanism of the Regulation of Organic Cation/Carnitine Transporter 1 (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines
      Tomoji Maeda, Masamichi Hirayama, Daisuke Kobayashi, Keiji Miyazawa and Ikumi Tamai
      Drug Metabolism and Disposition March 2007, 35 (3) 394-401; DOI: https://doi.org/10.1124/dmd.106.012112

  12. Komoriya, Kazumi

    1. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

  13. Kubo, Yoshiyuki

    1. Functional Expression of Stereoselective Metabolism of Cephalexin by Exogenous Transfection of Oligopeptide Transporter PEPT1
      Keisuke Mitsuoka, Yukio Kato, Yoshiyuki Kubo and Akira Tsuji
      Drug Metabolism and Disposition March 2007, 35 (3) 356-362; DOI: https://doi.org/10.1124/dmd.106.010405

  14. Kume, Toshiyuki

    1. Effect of Oral Ketoconazole on Intestinal First-Pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys
      Akihito Ogasawara, Toshiyuki Kume and Emiko Kazama
      Drug Metabolism and Disposition March 2007, 35 (3) 410-418; DOI: https://doi.org/10.1124/dmd.106.011288

L

  1. Lawton, Michael P.

    1. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

  2. Lee, Kuo-Hsiung

    1. Glucuronidation of Anti-HIV Drug Candidate Bevirimat: Identification of Human UDP-glucuronosyltransferases and Species Differences
      Zhiming Wen, David E. Martin, Peter Bullock, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 440-448; DOI: https://doi.org/10.1124/dmd.106.012815

  3. Lickteig, Andrew J.

    1. Differential Regulation of Hepatic Transporters in the Absence of Tumor Necrosis Factor-α, Interleukin-1β, Interleukin-6, and Nuclear Factor-κB in Two Models of Cholestasis
      Andrew J. Lickteig, Angela L. Slitt, Melek C. Arkan, Michael Karin and Nathan J. Cherrington
      Drug Metabolism and Disposition March 2007, 35 (3) 402-409; DOI: https://doi.org/10.1124/dmd.106.012138

  4. Lindahl, Ronald

    1. Constitutive and 3-Methylcholanthrene-Induced Rat ALDH3A1 Expression Is Mediated by Multiple Xenobiotic Response Elements
      Richard Reisdorph and Ronald Lindahl
      Drug Metabolism and Disposition March 2007, 35 (3) 386-393; DOI: https://doi.org/10.1124/dmd.106.012393

  5. Lindenmaier, Heike

    1. Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by Nucleoside, Nucleotide, and Non-Nucleoside Reverse Transcriptase Inhibitors
      Johanna Weiss, Dirk Theile, Nahal Ketabi-Kiyanvash, Heike Lindenmaier and Walter Emil Haefeli
      Drug Metabolism and Disposition March 2007, 35 (3) 340-344; DOI: https://doi.org/10.1124/dmd.106.012765

M

  1. Mackenzie, P. I.

    1. The Glucuronidation of Δ4-3-Keto C19- and C21-Hydroxysteroids by Human Liver Microsomal and Recombinant UDP-glucuronosyltransferases (UGTs): 6α- and 21-Hydroxyprogesterone Are Selective Substrates for UGT2B7
      K. Bowalgaha, D. J. Elliot, P. I. Mackenzie, K. M. Knights and J. O. Miners
      Drug Metabolism and Disposition March 2007, 35 (3) 363-370; DOI: https://doi.org/10.1124/dmd.106.013052

  2. Maeda, Tomoji

    1. Mechanism of the Regulation of Organic Cation/Carnitine Transporter 1 (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines
      Tomoji Maeda, Masamichi Hirayama, Daisuke Kobayashi, Keiji Miyazawa and Ikumi Tamai
      Drug Metabolism and Disposition March 2007, 35 (3) 394-401; DOI: https://doi.org/10.1124/dmd.106.012112

  3. Mankowski, Dayna C.

    1. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

  4. Marquet, Pierre

    1. Metabolism of Sirolimus in the Presence or Absence of Cyclosporine by Genotyped Human Liver Microsomes and Recombinant Cytochromes P450 3A4 and 3A5
      Nicolas Picard, Nassim Djebli, François-Ludovic Sauvage and Pierre Marquet
      Drug Metabolism and Disposition March 2007, 35 (3) 350-355; DOI: https://doi.org/10.1124/dmd.106.012161

  5. Martin, David E.

    1. Glucuronidation of Anti-HIV Drug Candidate Bevirimat: Identification of Human UDP-glucuronosyltransferases and Species Differences
      Zhiming Wen, David E. Martin, Peter Bullock, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 440-448; DOI: https://doi.org/10.1124/dmd.106.012815

  6. Miles, Kristini K.

    1. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

  7. Miners, J. O.

    1. The Glucuronidation of Δ4-3-Keto C19- and C21-Hydroxysteroids by Human Liver Microsomal and Recombinant UDP-glucuronosyltransferases (UGTs): 6α- and 21-Hydroxyprogesterone Are Selective Substrates for UGT2B7
      K. Bowalgaha, D. J. Elliot, P. I. Mackenzie, K. M. Knights and J. O. Miners
      Drug Metabolism and Disposition March 2007, 35 (3) 363-370; DOI: https://doi.org/10.1124/dmd.106.013052

  8. Mitsuoka, Keisuke

    1. Functional Expression of Stereoselective Metabolism of Cephalexin by Exogenous Transfection of Oligopeptide Transporter PEPT1
      Keisuke Mitsuoka, Yukio Kato, Yoshiyuki Kubo and Akira Tsuji
      Drug Metabolism and Disposition March 2007, 35 (3) 356-362; DOI: https://doi.org/10.1124/dmd.106.010405

  9. Miyazawa, Keiji

    1. Mechanism of the Regulation of Organic Cation/Carnitine Transporter 1 (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines
      Tomoji Maeda, Masamichi Hirayama, Daisuke Kobayashi, Keiji Miyazawa and Ikumi Tamai
      Drug Metabolism and Disposition March 2007, 35 (3) 394-401; DOI: https://doi.org/10.1124/dmd.106.012112

  10. Momose, Yasunori

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

  11. Murayama, Norie

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

N

  1. Nagashima, Satomi

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

  2. Nakajima, Miki

    1. CYP2A13 Metabolizes the Substrates of Human CYP1A2, Phenacetin, and Theophylline
      Tatsuki Fukami, Miki Nakajima, Haruko Sakai, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition March 2007, 35 (3) 335-339; DOI: https://doi.org/10.1124/dmd.106.011064

  3. Nakamura, Hiroyoshi

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  4. Nishigaki, Ryuichiro

    1. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

O

  1. O'Donnell, Charles J.

    1. The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
      Charles J. O'Donnell, Ken Grime, Paul Courtney, Dean Slee and Robert J. Riley
      Drug Metabolism and Disposition March 2007, 35 (3) 381-385; DOI: https://doi.org/10.1124/dmd.106.012344

  2. Ogasawara, Akihito

    1. Effect of Oral Ketoconazole on Intestinal First-Pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys
      Akihito Ogasawara, Toshiyuki Kume and Emiko Kazama
      Drug Metabolism and Disposition March 2007, 35 (3) 410-418; DOI: https://doi.org/10.1124/dmd.106.011288

  3. Ohmori, Shigeru

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  4. Ohsuye, Kazuhiro

    1. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

  5. Olson, Emily R.

    1. Pharmacokinetics and Pharmacodynamics of Alfentanil in P-Glycoprotein-Competent and P-Glycoprotein-Deficient Mice: P-Glycoprotein Efflux Alters Alfentanil Brain Disposition and Antinociception
      J. Cory Kalvass, Emily R. Olson and Gary M. Pollack
      Drug Metabolism and Disposition March 2007, 35 (3) 455-459; DOI: https://doi.org/10.1124/dmd.106.011445

  6. Omiecinski, Curtis J.

    1. CAR2 Displays Unique Ligand Binding and RXRα Heterodimerization Characteristics
      Scott S. Auerbach, Joshua G. DeKeyser, Matthew A. Stoner and Curtis J. Omiecinski
      Drug Metabolism and Disposition March 2007, 35 (3) 428-439; DOI: https://doi.org/10.1124/dmd.106.012641

P

  1. Picard, Nicolas

    1. Metabolism of Sirolimus in the Presence or Absence of Cyclosporine by Genotyped Human Liver Microsomes and Recombinant Cytochromes P450 3A4 and 3A5
      Nicolas Picard, Nassim Djebli, François-Ludovic Sauvage and Pierre Marquet
      Drug Metabolism and Disposition March 2007, 35 (3) 350-355; DOI: https://doi.org/10.1124/dmd.106.012161

  2. Pollack, Gary M.

    1. Pharmacokinetics and Pharmacodynamics of Alfentanil in P-Glycoprotein-Competent and P-Glycoprotein-Deficient Mice: P-Glycoprotein Efflux Alters Alfentanil Brain Disposition and Antinociception
      J. Cory Kalvass, Emily R. Olson and Gary M. Pollack
      Drug Metabolism and Disposition March 2007, 35 (3) 455-459; DOI: https://doi.org/10.1124/dmd.106.011445

R

  1. Reisdorph, Richard

    1. Constitutive and 3-Methylcholanthrene-Induced Rat ALDH3A1 Expression Is Mediated by Multiple Xenobiotic Response Elements
      Richard Reisdorph and Ronald Lindahl
      Drug Metabolism and Disposition March 2007, 35 (3) 386-393; DOI: https://doi.org/10.1124/dmd.106.012393

  2. Remmel, Rory P.

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  3. Riley, Robert J.

    1. The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
      Charles J. O'Donnell, Ken Grime, Paul Courtney, Dean Slee and Robert J. Riley
      Drug Metabolism and Disposition March 2007, 35 (3) 381-385; DOI: https://doi.org/10.1124/dmd.106.012344

  4. Ritter, Joseph K.

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243
    2. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

  5. Rostami-Hodjegan, Amin

    1. Misuse of the Well-Stirred Model of Hepatic Drug Clearance
      Jiansong Yang, Masoud Jamei, Karen R. Yeo, Amin Rostami-Hodjegan and Geoffrey T. Tucker
      Drug Metabolism and Disposition March 2007, 35 (3) 501-502; DOI: https://doi.org/10.1124/dmd.106.013359

S

  1. Sakai, Haruko

    1. CYP2A13 Metabolizes the Substrates of Human CYP1A2, Phenacetin, and Theophylline
      Tatsuki Fukami, Miki Nakajima, Haruko Sakai, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition March 2007, 35 (3) 335-339; DOI: https://doi.org/10.1124/dmd.106.011064

  2. Sauvage, François-Ludovic

    1. Metabolism of Sirolimus in the Presence or Absence of Cyclosporine by Genotyped Human Liver Microsomes and Recombinant Cytochromes P450 3A4 and 3A5
      Nicolas Picard, Nassim Djebli, François-Ludovic Sauvage and Pierre Marquet
      Drug Metabolism and Disposition March 2007, 35 (3) 350-355; DOI: https://doi.org/10.1124/dmd.106.012161

  3. Senekeo-Effenberger, Kathy

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  4. Shimizu, Makiko

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

  5. Shimomura, Hitoshi

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  6. Slee, Dean

    1. The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting
      Charles J. O'Donnell, Ken Grime, Paul Courtney, Dean Slee and Robert J. Riley
      Drug Metabolism and Disposition March 2007, 35 (3) 381-385; DOI: https://doi.org/10.1124/dmd.106.012344

  7. Slitt, Angela L.

    1. Differential Regulation of Hepatic Transporters in the Absence of Tumor Necrosis Factor-α, Interleukin-1β, Interleukin-6, and Nuclear Factor-κB in Two Models of Cholestasis
      Andrew J. Lickteig, Angela L. Slitt, Melek C. Arkan, Michael Karin and Nathan J. Cherrington
      Drug Metabolism and Disposition March 2007, 35 (3) 402-409; DOI: https://doi.org/10.1124/dmd.106.012138

  8. Smith, Philip C.

    1. UDP-Glucuronosyltransferase 1A1 Is the Principal Enzyme Responsible for Etoposide Glucuronidation in Human Liver and Intestinal Microsomes: Structural Characterization of Phenolic and Alcoholic Glucuronides of Etoposide and Estimation of Enzyme Kinetics
      Zhiming Wen, Melanie N. Tallman, Shazia Y. Ali and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 371-380; DOI: https://doi.org/10.1124/dmd.106.012732
    2. Glucuronidation of Anti-HIV Drug Candidate Bevirimat: Identification of Human UDP-glucuronosyltransferases and Species Differences
      Zhiming Wen, David E. Martin, Peter Bullock, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 440-448; DOI: https://doi.org/10.1124/dmd.106.012815
    3. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

  9. Stern, Stephan T.

    1. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

  10. Stoner, Matthew A.

    1. CAR2 Displays Unique Ligand Binding and RXRα Heterodimerization Characteristics
      Scott S. Auerbach, Joshua G. DeKeyser, Matthew A. Stoner and Curtis J. Omiecinski
      Drug Metabolism and Disposition March 2007, 35 (3) 428-439; DOI: https://doi.org/10.1124/dmd.106.012641

  11. Sugiyama, Yuichi

    1. Characterization of the Hepatic Disposition of Lanoteplase, a Rationally Designed Variant of Tissue Plasminogen Activator in Rodents
      Kazumi Komoriya, Yukio Kato, Yujiro Hayashi, Kazuhiro Ohsuye, Ryuichiro Nishigaki and Yuichi Sugiyama
      Drug Metabolism and Disposition March 2007, 35 (3) 469-475; DOI: https://doi.org/10.1124/dmd.106.012518

T

  1. Tallman, Melanie N.

    1. UDP-Glucuronosyltransferase 1A1 Is the Principal Enzyme Responsible for Etoposide Glucuronidation in Human Liver and Intestinal Microsomes: Structural Characterization of Phenolic and Alcoholic Glucuronides of Etoposide and Estimation of Enzyme Kinetics
      Zhiming Wen, Melanie N. Tallman, Shazia Y. Ali and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 371-380; DOI: https://doi.org/10.1124/dmd.106.012732
    2. Gender-Related Differences in Mycophenolate Mofetil-Induced Gastrointestinal Toxicity in Rats
      Stephan T. Stern, Melanie N. Tallman, Kristini K. Miles, Joseph K. Ritter, Robert E. Dupuis and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 449-454; DOI: https://doi.org/10.1124/dmd.106.012013

  2. Tamai, Ikumi

    1. Mechanism of the Regulation of Organic Cation/Carnitine Transporter 1 (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines
      Tomoji Maeda, Masamichi Hirayama, Daisuke Kobayashi, Keiji Miyazawa and Ikumi Tamai
      Drug Metabolism and Disposition March 2007, 35 (3) 394-401; DOI: https://doi.org/10.1124/dmd.106.012112

  3. Tanaka, Kanako

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  4. Theile, Dirk

    1. Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by Nucleoside, Nucleotide, and Non-Nucleoside Reverse Transcriptase Inhibitors
      Johanna Weiss, Dirk Theile, Nahal Ketabi-Kiyanvash, Heike Lindenmaier and Walter Emil Haefeli
      Drug Metabolism and Disposition March 2007, 35 (3) 340-344; DOI: https://doi.org/10.1124/dmd.106.012765

  5. Torimoto, Nao

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  6. Toyama, Ken-Ichi

    1. Helices F–G Are Important for the Substrate Specificities of CYP3A7
      Nao Torimoto, Itsuko Ishii, Ken-Ichi Toyama, Masayuki Hata, Kanako Tanaka, Hitoshi Shimomura, Hiroyoshi Nakamura, Noritaka Ariyoshi, Shigeru Ohmori and Mitsukazu Kitada
      Drug Metabolism and Disposition March 2007, 35 (3) 484-492; DOI: https://doi.org/10.1124/dmd.106.011304

  7. Treadway, Judith L.

    1. Three-Dimensional Quantitative Structure-Activity Relationship Analysis of Human CYP51 Inhibitors
      Sean Ekins, Dayna C. Mankowski, Dennis J. Hoover, Michael P. Lawton, Judith L. Treadway and H. James Harwood
      Drug Metabolism and Disposition March 2007, 35 (3) 493-500; DOI: https://doi.org/10.1124/dmd.106.013888

  8. Trottier, Jocelyn

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

  9. Tsuji, Akira

    1. Functional Expression of Stereoselective Metabolism of Cephalexin by Exogenous Transfection of Oligopeptide Transporter PEPT1
      Keisuke Mitsuoka, Yukio Kato, Yoshiyuki Kubo and Akira Tsuji
      Drug Metabolism and Disposition March 2007, 35 (3) 356-362; DOI: https://doi.org/10.1124/dmd.106.010405

  10. Tucker, Geoffrey T.

    1. Misuse of the Well-Stirred Model of Hepatic Drug Clearance
      Jiansong Yang, Masoud Jamei, Karen R. Yeo, Amin Rostami-Hodjegan and Geoffrey T. Tucker
      Drug Metabolism and Disposition March 2007, 35 (3) 501-502; DOI: https://doi.org/10.1124/dmd.106.013359

  11. Tukey, Robert H.

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

W

  1. Watanabe, Tanya A.

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  2. Weiss, Johanna

    1. Inhibition of MRP1/ABCC1, MRP2/ABCC2, and MRP3/ABCC3 by Nucleoside, Nucleotide, and Non-Nucleoside Reverse Transcriptase Inhibitors
      Johanna Weiss, Dirk Theile, Nahal Ketabi-Kiyanvash, Heike Lindenmaier and Walter Emil Haefeli
      Drug Metabolism and Disposition March 2007, 35 (3) 340-344; DOI: https://doi.org/10.1124/dmd.106.012765

  3. Wen, Zhiming

    1. UDP-Glucuronosyltransferase 1A1 Is the Principal Enzyme Responsible for Etoposide Glucuronidation in Human Liver and Intestinal Microsomes: Structural Characterization of Phenolic and Alcoholic Glucuronides of Etoposide and Estimation of Enzyme Kinetics
      Zhiming Wen, Melanie N. Tallman, Shazia Y. Ali and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 371-380; DOI: https://doi.org/10.1124/dmd.106.012732
    2. Glucuronidation of Anti-HIV Drug Candidate Bevirimat: Identification of Human UDP-glucuronosyltransferases and Species Differences
      Zhiming Wen, David E. Martin, Peter Bullock, Kuo-Hsiung Lee and Philip C. Smith
      Drug Metabolism and Disposition March 2007, 35 (3) 440-448; DOI: https://doi.org/10.1124/dmd.106.012815

X

  1. Xiang-Jun, Zhou

    1. Inhibitory Effects of Benzoate on Chiral Inversion and Clearance of NG-Nitro-Arginine in Conscious Rats
      Xin Yan-Fei, Zhou Xiang-Jun, Lu Jie and Wang Yong-Xiang
      Drug Metabolism and Disposition March 2007, 35 (3) 331-334; DOI: https://doi.org/10.1124/dmd.106.011429

Y

  1. Yamamoto, Akitoshi

    1. Involvement of CYP2A6 in the Formation of a Novel Metabolite, 3-Hydroxypilocarpine, from Pilocarpine in Human Liver Microsomes
      Takuro Endo, Masaaki Ban, Kazuma Hirata, Akitoshi Yamamoto, Yoshiki Hara and Yasunori Momose
      Drug Metabolism and Disposition March 2007, 35 (3) 476-483; DOI: https://doi.org/10.1124/dmd.106.013425

  2. Yamazaki, Hiroshi

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

  3. Yan-Fei, Xin

    1. Inhibitory Effects of Benzoate on Chiral Inversion and Clearance of NG-Nitro-Arginine in Conscious Rats
      Xin Yan-Fei, Zhou Xiang-Jun, Lu Jie and Wang Yong-Xiang
      Drug Metabolism and Disposition March 2007, 35 (3) 331-334; DOI: https://doi.org/10.1124/dmd.106.011429

  4. Yang, Jiansong

    1. Misuse of the Well-Stirred Model of Hepatic Drug Clearance
      Jiansong Yang, Masoud Jamei, Karen R. Yeo, Amin Rostami-Hodjegan and Geoffrey T. Tucker
      Drug Metabolism and Disposition March 2007, 35 (3) 501-502; DOI: https://doi.org/10.1124/dmd.106.013359

  5. Yano, Hiroshi

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094

  6. Yeo, Karen R.

    1. Misuse of the Well-Stirred Model of Hepatic Drug Clearance
      Jiansong Yang, Masoud Jamei, Karen R. Yeo, Amin Rostami-Hodjegan and Geoffrey T. Tucker
      Drug Metabolism and Disposition March 2007, 35 (3) 501-502; DOI: https://doi.org/10.1124/dmd.106.013359

  7. Yokoi, Tsuyoshi

    1. CYP2A13 Metabolizes the Substrates of Human CYP1A2, Phenacetin, and Theophylline
      Tatsuki Fukami, Miki Nakajima, Haruko Sakai, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition March 2007, 35 (3) 335-339; DOI: https://doi.org/10.1124/dmd.106.011064

  8. Yong-Xiang, Wang

    1. Inhibitory Effects of Benzoate on Chiral Inversion and Clearance of NG-Nitro-Arginine in Conscious Rats
      Xin Yan-Fei, Zhou Xiang-Jun, Lu Jie and Wang Yong-Xiang
      Drug Metabolism and Disposition March 2007, 35 (3) 331-334; DOI: https://doi.org/10.1124/dmd.106.011429

  9. Yu, Rosie Z.

    1. Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100
      Rosie Z. Yu, Tae-Won Kim, An Hong, Tanya A. Watanabe, Hans J. Gaus and Richard S. Geary
      Drug Metabolism and Disposition March 2007, 35 (3) 460-468; DOI: https://doi.org/10.1124/dmd.106.012401

  10. Yueh, Mei-Fei

    1. Expression of the Human UGT1 Locus in Transgenic Mice by 4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic Acid (WY-14643) and Implications on Drug Metabolism through Peroxisome Proliferator-Activated Receptor α Activation
      Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace-Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argikar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Joseph K. Ritter, Olivier Barbier and Robert H. Tukey
      Drug Metabolism and Disposition March 2007, 35 (3) 419-427; DOI: https://doi.org/10.1124/dmd.106.013243

Z

  1. Zhang, Jun

    1. Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities
      Makiko Shimizu, Hiroshi Yano, Satomi Nagashima, Norie Murayama, Jun Zhang, John R. Cashman and Hiroshi Yamazaki
      Drug Metabolism and Disposition March 2007, 35 (3) 328-330; DOI: https://doi.org/10.1124/dmd.106.013094
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