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Research ArticleArticle

Evaluation of 3-O-Methylfluorescein as a Selective Fluorometric Substrate for CYP2C19 in Human Liver Microsomes

Sirimas Sudsakorn, Jeffrey Skell, David A. Williams, Thomas J. O'Shea and Hanlan Liu
Drug Metabolism and Disposition June 2007, 35 (6) 841-847; DOI: https://doi.org/10.1124/dmd.106.014472
Sirimas Sudsakorn
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Jeffrey Skell
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David A. Williams
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Thomas J. O'Shea
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Hanlan Liu
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Article Information

vol. 35 no. 6 841-847
DOI 
https://doi.org/10.1124/dmd.106.014472
PubMed 
17332142

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 21, 2006
  • Accepted February 27, 2007
  • Published online May 18, 2007.

Article Versions

  • Earlier version (March 1, 2007 - 08:43).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sirimas Sudsakorn,
  2. Jeffrey Skell,
  3. David A. Williams,
  4. Thomas J. O'Shea and
  5. Hanlan Liu
  1. DMPK and Pharmaceutics Department, and Drug and Biomaterial Research and Development, Genzyme Corporation, Waltham, Massachusetts (S.S., J.S., T.J.O., H.L.); and Department of Pharmaceutical Sciences, Massachusetts College of Pharmacy and Health Sciences, Boston, Massachusetts (D.A.W.)
  1. Address correspondence to:
    Hanlan Liu, DMPK and Pharmaceutics Department, Drug and Biomaterial R&D, Genzyme Corporation, 153 2nd Avenue, Waltham, MA 02451. E-mail: hanlan.liu{at}genzyme.com
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Drug Metabolism and Disposition: 35 (6)
Drug Metabolism and Disposition
Vol. 35, Issue 6
1 Jun 2007
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Research ArticleArticle

Evaluation of 3-O-Methylfluorescein as a Selective Fluorometric Substrate for CYP2C19 in Human Liver Microsomes

Sirimas Sudsakorn, Jeffrey Skell, David A. Williams, Thomas J. O'Shea and Hanlan Liu
Drug Metabolism and Disposition June 1, 2007, 35 (6) 841-847; DOI: https://doi.org/10.1124/dmd.106.014472

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Research ArticleArticle

Evaluation of 3-O-Methylfluorescein as a Selective Fluorometric Substrate for CYP2C19 in Human Liver Microsomes

Sirimas Sudsakorn, Jeffrey Skell, David A. Williams, Thomas J. O'Shea and Hanlan Liu
Drug Metabolism and Disposition June 1, 2007, 35 (6) 841-847; DOI: https://doi.org/10.1124/dmd.106.014472
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