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Research ArticleArticle

Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo

Matthew G. Soars, Ken Grime, Joanne L. Sproston, Peter J. H. Webborn and Robert J. Riley
Drug Metabolism and Disposition June 2007, 35 (6) 859-865; DOI: https://doi.org/10.1124/dmd.106.014464

Article Information

vol. 35 no. 6 859-865
DOI 
https://doi.org/10.1124/dmd.106.014464
PubMed 
17344337
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 20, 2006
  • Accepted March 1, 2007
  • Published online May 18, 2007.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matthew G. Soars,
  2. Ken Grime,
  3. Joanne L. Sproston,
  4. Peter J. H. Webborn and
  5. Robert J. Riley
  1. Department of Physical and Metabolic Science, AstraZeneca Charnwood, Loughborough, Leics, England
  1. Address correspondence to:
    Dr. Matt Soars, Department of Physical and Metabolic Science, AstraZeneca Charnwood, Bakewell Road, Loughborough, Leics, LE11 5RH, England. E-mail: matt-soars{at}astrazeneca.com
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Research ArticleArticle

Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo

Matthew G. Soars, Ken Grime, Joanne L. Sproston, Peter J. H. Webborn and Robert J. Riley
Drug Metabolism and Disposition June 1, 2007, 35 (6) 859-865; DOI: https://doi.org/10.1124/dmd.106.014464
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