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Research ArticleArticle

Molecular Mechanism of Basal CYP3A4 Regulation by Hepatocyte Nuclear Factor 4α: Evidence for Direct Regulation in the Intestine

Heike Tegude, Anke Schnabel, Ulrich M. Zanger, Kathrin Klein, Michel Eichelbaum and Oliver Burk
Drug Metabolism and Disposition June 2007, 35 (6) 946-954; DOI: https://doi.org/10.1124/dmd.106.013565

Article Information

vol. 35 no. 6 946-954
DOI 
https://doi.org/10.1124/dmd.106.013565
PubMed 
17344340
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 26, 2006
  • Accepted March 1, 2007
  • Published online May 18, 2007.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Heike Tegude,
  2. Anke Schnabel,
  3. Ulrich M. Zanger,
  4. Kathrin Klein,
  5. Michel Eichelbaum and
  6. Oliver Burk
  1. Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany, and University of Tübingen, Tübingen, Germany
  1. Address correspondence to:
    Dr. Oliver Burk, Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Auerbachstrasse 112, D-70376 Stuttgart, Germany. E-mail: oliver.burk{at}ikp-stuttgart.de
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Research ArticleArticle

Molecular Mechanism of Basal CYP3A4 Regulation by Hepatocyte Nuclear Factor 4α: Evidence for Direct Regulation in the Intestine

Heike Tegude, Anke Schnabel, Ulrich M. Zanger, Kathrin Klein, Michel Eichelbaum and Oliver Burk
Drug Metabolism and Disposition June 1, 2007, 35 (6) 946-954; DOI: https://doi.org/10.1124/dmd.106.013565
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