Risk Assessment for Drug-Drug Interaction Caused by Metabolism-Based Inhibition of CYP3A Using Automated in Vitro Assay Systems and Its Application in the Early Drug Discovery Process

Akiko Watanabe; Koichi Nakamura; Noriko Okudaira; Osamu Okazaki; Ken-ichi Sudo

doi:10.1124/dmd.107.015016

Article Information

vol. 35 no. 7 1232-1238

DOI

https://doi.org/10.1124/dmd.107.015016

PubMed

17392390

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0090-9556

Online ISSN

1521-009X

History

Received January 30, 2007
Accepted March 27, 2007
Published online June 19, 2007.

Article Versions

Earlier version (March 28, 2007 - 06:43).
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The American Society for Pharmacology and Experimental Therapeutics

Author Information

Akiko Watanabe,
Koichi Nakamura,
Noriko Okudaira,
Osamu Okazaki and
Ken-ichi Sudo

Drug Metabolism & Physicochemistry Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan

Address correspondence to:
Akiko Watanabe, 16-13, Kita-Kasai 1-Chome Edogawa-ku, Tokyo 134-8630 Japan. E-mail: morikhlu{at}daiichipharm.co.jp

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