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Research ArticleArticle

Risk Assessment for Drug-Drug Interaction Caused by Metabolism-Based Inhibition of CYP3A Using Automated in Vitro Assay Systems and Its Application in the Early Drug Discovery Process

Akiko Watanabe, Koichi Nakamura, Noriko Okudaira, Osamu Okazaki and Ken-ichi Sudo
Drug Metabolism and Disposition July 2007, 35 (7) 1232-1238; DOI: https://doi.org/10.1124/dmd.107.015016

Article Information

vol. 35 no. 7 1232-1238
DOI 
https://doi.org/10.1124/dmd.107.015016
PubMed 
17392390
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 30, 2007
  • Accepted March 27, 2007
  • Published online June 19, 2007.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Akiko Watanabe,
  2. Koichi Nakamura,
  3. Noriko Okudaira,
  4. Osamu Okazaki and
  5. Ken-ichi Sudo
  1. Drug Metabolism & Physicochemistry Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan
  1. Address correspondence to:
    Akiko Watanabe, 16-13, Kita-Kasai 1-Chome Edogawa-ku, Tokyo 134-8630 Japan. E-mail: morikhlu{at}daiichipharm.co.jp
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Research ArticleArticle

Risk Assessment for Drug-Drug Interaction Caused by Metabolism-Based Inhibition of CYP3A Using Automated in Vitro Assay Systems and Its Application in the Early Drug Discovery Process

Akiko Watanabe, Koichi Nakamura, Noriko Okudaira, Osamu Okazaki and Ken-ichi Sudo
Drug Metabolism and Disposition July 1, 2007, 35 (7) 1232-1238; DOI: https://doi.org/10.1124/dmd.107.015016
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