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Index by author

September 01, 2007; Volume 35,Issue 9

A

  1. Abass, Khaled

    1. Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes
      Khaled Abass, Petri Reponen, Miia Turpeinen, Jorma Jalonen and Olavi Pelkonen
      Drug Metabolism and Disposition September 2007, 35 (9) 1634-1641; DOI: https://doi.org/10.1124/dmd.107.016295

  2. Aitken, Alison E.

    1. Gene-Specific Effects of Inflammatory Cytokines on Cytochrome P450 2C, 2B6 and 3A4 mRNA Levels in Human Hepatocytes
      Alison E. Aitken and Edward T. Morgan
      Drug Metabolism and Disposition September 2007, 35 (9) 1687-1693; DOI: https://doi.org/10.1124/dmd.107.015511

  3. Akaho, Nami

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  4. Aly, Al

    1. Detection of Haptenated Proteins in Organotypic Human Skin Explant Cultures Exposed to Dapsone
      Sanjoy Roychowdhury, Albert E. Cram, Al Aly and Craig K. Svensson
      Drug Metabolism and Disposition September 2007, 35 (9) 1463-1465; DOI: https://doi.org/10.1124/dmd.107.015560

  5. Anderson, Bradley D.

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  6. Anier, Kaili

    1. Inhibition of Human Thiopurine S-Methyltransferase by Various Nonsteroidal Anti-inflammatory Drugs in Vitro: A Mechanism for Possible Drug Interactions
      Kersti Oselin and Kaili Anier
      Drug Metabolism and Disposition September 2007, 35 (9) 1452-1454; DOI: https://doi.org/10.1124/dmd.107.016287

  7. Antonsson, Madeleine

    1. In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids
      Markus Fridén, Anubha Gupta, Madeleine Antonsson, Ulf Bredberg and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2007, 35 (9) 1711-1719; DOI: https://doi.org/10.1124/dmd.107.015222

  8. Arai, Midori A.

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  9. Avram, Michael J.

    1. A Minimal Physiological Model of Thiopental Distribution Kinetics Based on a Multiple Indicator Approach
      Michael Weiss, Tom C. Krejcie and Michael J. Avram
      Drug Metabolism and Disposition September 2007, 35 (9) 1525-1532; DOI: https://doi.org/10.1124/dmd.106.014209

  10. Azrolan, Neal

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

B

  1. Ballard, J. E.

    1. Hepatic Metabolism of MK-0457, a Potent Aurora Kinase Inhibitor: Interspecies Comparison and Role of Human Cytochrome P450 and Flavin-Containing Monooxygenase
      J. E. Ballard, T. Prueksaritanont and C. Tang
      Drug Metabolism and Disposition September 2007, 35 (9) 1447-1451; DOI: https://doi.org/10.1124/dmd.107.015438

  2. Bánsághi, Száva

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  3. Barker, David F.

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

  4. Bartholomé, Kilian

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  5. Báthori, György

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  6. Bredberg, Ulf

    1. In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids
      Markus Fridén, Anubha Gupta, Madeleine Antonsson, Ulf Bredberg and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2007, 35 (9) 1711-1719; DOI: https://doi.org/10.1124/dmd.107.015222

  7. Bu, Hai-Zhi

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

C

  1. Cai, Ping

    1. In Vitro Metabolic Study of Temsirolimus: Preparation, Isolation, and Identification of the Metabolites
      Ping Cai, Rushung Tsao and Mark E. Ruppen
      Drug Metabolism and Disposition September 2007, 35 (9) 1554-1563; DOI: https://doi.org/10.1124/dmd.107.014746

  2. Cha, In-June

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  3. Chen, Tai C.

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  4. Choi, Sung-Up

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  5. Collier, Abby C.

    1. Pediatric Development of Glucuronidation: The Ontogeny of Hepatic UGT1A4
      Shogo J. Miyagi and Abby C. Collier
      Drug Metabolism and Disposition September 2007, 35 (9) 1587-1592; DOI: https://doi.org/10.1124/dmd.107.015214

  6. Cram, Albert E.

    1. Detection of Haptenated Proteins in Organotypic Human Skin Explant Cultures Exposed to Dapsone
      Sanjoy Roychowdhury, Albert E. Cram, Al Aly and Craig K. Svensson
      Drug Metabolism and Disposition September 2007, 35 (9) 1463-1465; DOI: https://doi.org/10.1124/dmd.107.015560

  7. Crow, J. Allen

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  8. Cui, Donghui

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  9. Czerwinski, Maciej

    1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
      Matthew Wortham, Maciej Czerwinski, Lin He, Andrew Parkinson and Yu-Jui Yvonne Wan
      Drug Metabolism and Disposition September 2007, 35 (9) 1700-1710; DOI: https://doi.org/10.1124/dmd.107.016436

D

  1. DeMaio, William

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  2. Denk, Helmut

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  3. DeVito, Michael J.

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  4. Ding, Xinxin

    1. Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine
      Qing-Yu Zhang, Laurence S. Kaminsky, Deborah Dunbar, Jin Zhang and Xinxin Ding
      Drug Metabolism and Disposition September 2007, 35 (9) 1617-1623; DOI: https://doi.org/10.1124/dmd.107.016543

  5. Doll, Mark A.

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

  6. Dunbar, Deborah

    1. Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine
      Qing-Yu Zhang, Laurence S. Kaminsky, Deborah Dunbar, Jin Zhang and Xinxin Ding
      Drug Metabolism and Disposition September 2007, 35 (9) 1617-1623; DOI: https://doi.org/10.1124/dmd.107.016543

E

  1. Ekins, Sean

    1. Computational Approaches That Predict Metabolic Intermediate Complex Formation with CYP3A4 (+b5)
      David R. Jones, Sean Ekins, Lang Li and Stephen D. Hall
      Drug Metabolism and Disposition September 2007, 35 (9) 1466-1475; DOI: https://doi.org/10.1124/dmd.106.014613

F

  1. Fickert, Peter

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  2. Fridén, Markus

    1. In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids
      Markus Fridén, Anubha Gupta, Madeleine Antonsson, Ulf Bredberg and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2007, 35 (9) 1711-1719; DOI: https://doi.org/10.1124/dmd.107.015222

  3. Fuchsbichler, Andrea

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  4. Fujimoto, Hiromi

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  5. Fujioka, Toshihiro

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  6. Fujiwara, Ryoichi

    1. Stereoselective Glucuronidation of 5-(4′-Hydroxyphenyl)-5-phenylhydantoin by Human UDP-Glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: Effects of UGT-UGT Interactions
      Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1679-1686; DOI: https://doi.org/10.1124/dmd.107.015909

  7. Fukui, Kosuke

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  8. Fukushima, Takeshi

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

G

  1. Glavinas, Hristos

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  2. Godin, Stephen J.

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  3. Gujral, Jaspreet S.

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  4. Gumhold, Judith

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  5. Gupta, Anubha

    1. In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids
      Markus Fridén, Anubha Gupta, Madeleine Antonsson, Ulf Bredberg and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2007, 35 (9) 1711-1719; DOI: https://doi.org/10.1124/dmd.107.015222

H

  1. Hall, Stephen D.

    1. Computational Approaches That Predict Metabolic Intermediate Complex Formation with CYP3A4 (+b5)
      David R. Jones, Sean Ekins, Lang Li and Stephen D. Hall
      Drug Metabolism and Disposition September 2007, 35 (9) 1466-1475; DOI: https://doi.org/10.1124/dmd.106.014613

  2. Hamada, Akinobu

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  3. Hammarlund-Udenaes, Margareta

    1. In Vitro Methods for Estimating Unbound Drug Concentrations in the Brain Interstitial and Intracellular Fluids
      Markus Fridén, Anubha Gupta, Madeleine Antonsson, Ulf Bredberg and Margareta Hammarlund-Udenaes
      Drug Metabolism and Disposition September 2007, 35 (9) 1711-1719; DOI: https://doi.org/10.1124/dmd.107.015222

  4. Harper, Dawn

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  5. Hattori, Akihiro

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  6. Hayashi, Keiko

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  7. He, Lin

    1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
      Matthew Wortham, Maciej Czerwinski, Lin He, Andrew Parkinson and Yu-Jui Yvonne Wan
      Drug Metabolism and Disposition September 2007, 35 (9) 1700-1710; DOI: https://doi.org/10.1124/dmd.107.016436

  8. Heikkinen, Aki T.

    1. Decrease in Intracellular Concentration Causes the Shift in Km Value of Efflux Pump Substrates
      Timo Korjamo, Heidi Kemiläinen, Aki T. Heikkinen and Jukka Mönkkönen
      Drug Metabolism and Disposition September 2007, 35 (9) 1574-1579; DOI: https://doi.org/10.1124/dmd.107.016014

  9. Hein, David W.

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

  10. Hidaka, Ryoji

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  11. Higashi, Ryunosuke

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

  12. Ho, Rodney J.Y.

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  13. Hoffmann, Matthew

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  14. Honma, Masashi

    1. Cholesterol-Lowering Effect of Ezetimibe in Uridine Diphosphate Glucuronosyltransferase 1A-Deficient (Gunn) Rats
      Takehito Yamamoto, Kousei Ito, Masashi Honma, Tappei Takada and Hiroshi Suzuki
      Drug Metabolism and Disposition September 2007, 35 (9) 1455-1458; DOI: https://doi.org/10.1124/dmd.107.015628

  15. Hreniuk, David

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  16. Hughes, Michael F.

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  17. Husain, Anwar

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

I

  1. Ikushiro, Shinichi

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  2. Imai, Kazuhiro

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  3. Imai, Teruko

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  4. Imai, Tomoyuki

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  5. Ito, Kousei

    1. Cholesterol-Lowering Effect of Ezetimibe in Uridine Diphosphate Glucuronosyltransferase 1A-Deficient (Gunn) Rats
      Takehito Yamamoto, Kousei Ito, Masashi Honma, Tappei Takada and Hiroshi Suzuki
      Drug Metabolism and Disposition September 2007, 35 (9) 1455-1458; DOI: https://doi.org/10.1124/dmd.107.015628

  6. Iwamoto, Marian

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

J

  1. Jaeschke, Hartmut

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  2. Jalonen, Jorma

    1. Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes
      Khaled Abass, Petri Reponen, Miia Turpeinen, Jorma Jalonen and Olavi Pelkonen
      Drug Metabolism and Disposition September 2007, 35 (9) 1634-1641; DOI: https://doi.org/10.1124/dmd.107.016295

  3. Janáky, Tamás

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  4. Jani, Márton

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  5. Jones, David R.

    1. Computational Approaches That Predict Metabolic Intermediate Complex Formation with CYP3A4 (+b5)
      David R. Jones, Sean Ekins, Lang Li and Stephen D. Hall
      Drug Metabolism and Disposition September 2007, 35 (9) 1466-1475; DOI: https://doi.org/10.1124/dmd.106.014613

  6. Jordan, Ronald A.

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  7. Jusko, William J.

    1. Interspecies Comparisons of Pharmacokinetics and Pharmacodynamics of Recombinant Human Erythropoietin
      Sukyung Woo and William J. Jusko
      Drug Metabolism and Disposition September 2007, 35 (9) 1672-1678; DOI: https://doi.org/10.1124/dmd.107.015248

K

  1. Kaddoumi, Amal

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  2. Kamakura, Masaki

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  3. Kaminsky, Laurence S.

    1. Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine
      Qing-Yu Zhang, Laurence S. Kaminsky, Deborah Dunbar, Jin Zhang and Xinxin Ding
      Drug Metabolism and Disposition September 2007, 35 (9) 1617-1623; DOI: https://doi.org/10.1124/dmd.107.016543

  4. Kang, Ping

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

  5. Karube, Yoshiharu

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  6. Kassahun, Kelem

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  7. Kato, Shigeaki

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  8. Katoh, Miki

    1. Glucuronidation of Thyroxine in Human Liver, Jejunum, and Kidney Microsomes
      Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1642-1648; DOI: https://doi.org/10.1124/dmd.107.016097
    2. Stereoselective Glucuronidation of 5-(4′-Hydroxyphenyl)-5-phenylhydantoin by Human UDP-Glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: Effects of UGT-UGT Interactions
      Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1679-1686; DOI: https://doi.org/10.1124/dmd.107.015909

  9. Kele, Zoltán

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  10. Keller, Daniela

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  11. Kemiläinen, Heidi

    1. Decrease in Intracellular Concentration Causes the Shift in Km Value of Efflux Pump Substrates
      Timo Korjamo, Heidi Kemiläinen, Aki T. Heikkinen and Jukka Mönkkönen
      Drug Metabolism and Disposition September 2007, 35 (9) 1574-1579; DOI: https://doi.org/10.1124/dmd.107.016014

  12. Kemper, Byron

    1. Subcellular Trafficking Signals of Constitutive Androstane Receptor: Evidence for a Nuclear Export Signal in the DNA-Binding Domain
      Jun Xia and Byron Kemper
      Drug Metabolism and Disposition September 2007, 35 (9) 1489-1494; DOI: https://doi.org/10.1124/dmd.107.016493

  13. Keppler, Dietrich

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  14. Kim, Eun-Young

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  15. Kim, Ho-Sook

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  16. Kim, Hyunmi

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  17. Kim, Kwon-Bok

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  18. Kinman, Loren

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  19. Kis, Emese

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  20. Kitamura, Ryuichi

    1. Decrease in Plasma Concentrations of Antiangiogenic Agent TSU-68 ((Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid) during Oral Administration Twice a Day to Rats
      Ryuichi Kitamura, Yoshio Yamamoto, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition September 2007, 35 (9) 1611-1616; DOI: https://doi.org/10.1124/dmd.106.014068

  21. Kittaka, Atsushi

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  22. Kóbori, László

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  23. Kőhalmy, Krisztina

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  24. Koomen, Gerrit-Jan

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  25. Korjamo, Timo

    1. Decrease in Intracellular Concentration Causes the Shift in Km Value of Efflux Pump Substrates
      Timo Korjamo, Heidi Kemiläinen, Aki T. Heikkinen and Jukka Mönkkönen
      Drug Metabolism and Disposition September 2007, 35 (9) 1574-1579; DOI: https://doi.org/10.1124/dmd.107.016014

  26. Kovács, Rita

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  27. Krajcsi, Péter

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  28. Krejcie, Tom C.

    1. A Minimal Physiological Model of Thiopental Distribution Kinetics Based on a Multiple Indicator Approach
      Michael Weiss, Tom C. Krejcie and Michael J. Avram
      Drug Metabolism and Disposition September 2007, 35 (9) 1525-1532; DOI: https://doi.org/10.1124/dmd.106.014209

L

  1. Lasseter, Kenneth

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  2. Letschert, Katrin

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  3. Li, Lang

    1. Computational Approaches That Predict Metabolic Intermediate Complex Formation with CYP3A4 (+b5)
      David R. Jones, Sean Ekins, Lang Li and Stephen D. Hall
      Drug Metabolism and Disposition September 2007, 35 (9) 1466-1475; DOI: https://doi.org/10.1124/dmd.106.014613

  4. Liu, Kwang-Hyeon

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  5. Liu, Yuan

    1. Isolation and Identification of Phase 1 Metabolites of Demethoxycurcumin in Rats
      Yongchi Zeng, Feng Qiu, Yuan Liu, Gexia Qu and Xinsheng Yao
      Drug Metabolism and Disposition September 2007, 35 (9) 1564-1573; DOI: https://doi.org/10.1124/dmd.107.015008

M

  1. Maeda, Tomoji

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

  2. Masa, Kengo

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  3. Matsunaga, Kazuhisa

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  4. Matsuzaki, Takanobu

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  5. McIntosh, Ian

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  6. Merschman, Shelia

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  7. Meyer, Urs A.

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  8. Miura, Masahiro

    1. Absorption, Metabolism, and Excretion of [14C]Imidafenacin, a New Compound for Treatment of Overactive Bladder, After Oral Administration to Healthy Male Subjects
      Satoshi Ohmori, Masahiro Miura, Chifuyu Toriumi, Yoshiaki Satoh and Tsuyoshi Ooie
      Drug Metabolism and Disposition September 2007, 35 (9) 1624-1633; DOI: https://doi.org/10.1124/dmd.107.016030

  9. Miyagi, Shogo J.

    1. Pediatric Development of Glucuronidation: The Ontogeny of Hepatic UGT1A4
      Shogo J. Miyagi and Abby C. Collier
      Drug Metabolism and Disposition September 2007, 35 (9) 1587-1592; DOI: https://doi.org/10.1124/dmd.107.015214

  10. Molnár, Éva

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  11. Mönkkönen, Jukka

    1. Decrease in Intracellular Concentration Causes the Shift in Km Value of Efflux Pump Substrates
      Timo Korjamo, Heidi Kemiläinen, Aki T. Heikkinen and Jukka Mönkkönen
      Drug Metabolism and Disposition September 2007, 35 (9) 1574-1579; DOI: https://doi.org/10.1124/dmd.107.016014

  12. Monostory, Katalin

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  13. Morgan, Edward T.

    1. Gene-Specific Effects of Inflammatory Cytokines on Cytochrome P450 2C, 2B6 and 3A4 mRNA Levels in Human Hepatocytes
      Alison E. Aitken and Edward T. Morgan
      Drug Metabolism and Disposition September 2007, 35 (9) 1687-1693; DOI: https://doi.org/10.1124/dmd.107.015511

N

  1. Nagata, Kiyoshi

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

  2. Nagayama, Sekio

    1. Decrease in Plasma Concentrations of Antiangiogenic Agent TSU-68 ((Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid) during Oral Administration Twice a Day to Rats
      Ryuichi Kitamura, Yoshio Yamamoto, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition September 2007, 35 (9) 1611-1616; DOI: https://doi.org/10.1124/dmd.106.014068

  3. Nakabayashi, Sachie

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  4. Nakajima, Miki

    1. Glucuronidation of Thyroxine in Human Liver, Jejunum, and Kidney Microsomes
      Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1642-1648; DOI: https://doi.org/10.1124/dmd.107.016097
    2. Stereoselective Glucuronidation of 5-(4′-Hydroxyphenyl)-5-phenylhydantoin by Human UDP-Glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: Effects of UGT-UGT Interactions
      Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1679-1686; DOI: https://doi.org/10.1124/dmd.107.015909

O

  1. Ohmori, Satoshi

    1. Absorption, Metabolism, and Excretion of [14C]Imidafenacin, a New Compound for Treatment of Overactive Bladder, After Oral Administration to Healthy Male Subjects
      Satoshi Ohmori, Masahiro Miura, Chifuyu Toriumi, Yoshiaki Satoh and Tsuyoshi Ooie
      Drug Metabolism and Disposition September 2007, 35 (9) 1624-1633; DOI: https://doi.org/10.1124/dmd.107.016030

  2. Ohta, Miho

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  3. Ooie, Tsuyoshi

    1. Absorption, Metabolism, and Excretion of [14C]Imidafenacin, a New Compound for Treatment of Overactive Bladder, After Oral Administration to Healthy Male Subjects
      Satoshi Ohmori, Masahiro Miura, Chifuyu Toriumi, Yoshiaki Satoh and Tsuyoshi Ooie
      Drug Metabolism and Disposition September 2007, 35 (9) 1624-1633; DOI: https://doi.org/10.1124/dmd.107.016030

  4. Oselin, Kersti

    1. Inhibition of Human Thiopurine S-Methyltransferase by Various Nonsteroidal Anti-inflammatory Drugs in Vitro: A Mechanism for Possible Drug Interactions
      Kersti Oselin and Kaili Anier
      Drug Metabolism and Disposition September 2007, 35 (9) 1452-1454; DOI: https://doi.org/10.1124/dmd.107.016287

  5. Otagiri, Masaki

    1. Decrease in Plasma Concentrations of Antiangiogenic Agent TSU-68 ((Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid) during Oral Administration Twice a Day to Rats
      Ryuichi Kitamura, Yoshio Yamamoto, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition September 2007, 35 (9) 1611-1616; DOI: https://doi.org/10.1124/dmd.106.014068

  6. Oyabu, Masanobu

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

P

  1. Pál, Ákos

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  2. Parkinson, Andrew

    1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
      Matthew Wortham, Maciej Czerwinski, Lin He, Andrew Parkinson and Yu-Jui Yvonne Wan
      Drug Metabolism and Disposition September 2007, 35 (9) 1700-1710; DOI: https://doi.org/10.1124/dmd.107.016436

  3. Pascussi, Jean-Marc

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  4. Pelkonen, Olavi

    1. Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes
      Khaled Abass, Petri Reponen, Miia Turpeinen, Jorma Jalonen and Olavi Pelkonen
      Drug Metabolism and Disposition September 2007, 35 (9) 1634-1641; DOI: https://doi.org/10.1124/dmd.107.016295

  5. Pool, William F.

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

  6. Porrogi, Pálma

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  7. Prough, Russell A.

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  8. Prueksaritanont, T.

    1. Hepatic Metabolism of MK-0457, a Potent Aurora Kinase Inhibitor: Interspecies Comparison and Role of Human Cytochrome P450 and Flavin-Containing Monooxygenase
      J. E. Ballard, T. Prueksaritanont and C. Tang
      Drug Metabolism and Disposition September 2007, 35 (9) 1447-1451; DOI: https://doi.org/10.1124/dmd.107.015438

Q

  1. Qiu, Feng

    1. Isolation and Identification of Phase 1 Metabolites of Demethoxycurcumin in Rats
      Yongchi Zeng, Feng Qiu, Yuan Liu, Gexia Qu and Xinsheng Yao
      Drug Metabolism and Disposition September 2007, 35 (9) 1564-1573; DOI: https://doi.org/10.1124/dmd.107.015008

  2. Qu, Gexia

    1. Isolation and Identification of Phase 1 Metabolites of Demethoxycurcumin in Rats
      Yongchi Zeng, Feng Qiu, Yuan Liu, Gexia Qu and Xinsheng Yao
      Drug Metabolism and Disposition September 2007, 35 (9) 1564-1573; DOI: https://doi.org/10.1124/dmd.107.015008

R

  1. Reponen, Petri

    1. Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes
      Khaled Abass, Petri Reponen, Miia Turpeinen, Jorma Jalonen and Olavi Pelkonen
      Drug Metabolism and Disposition September 2007, 35 (9) 1634-1641; DOI: https://doi.org/10.1124/dmd.107.016295

  2. Rius, Maria

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  3. Ross, Matthew K.

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  4. Roychowdhury, Sanjoy

    1. Detection of Haptenated Proteins in Organotypic Human Skin Explant Cultures Exposed to Dapsone
      Sanjoy Roychowdhury, Albert E. Cram, Al Aly and Craig K. Svensson
      Drug Metabolism and Disposition September 2007, 35 (9) 1463-1465; DOI: https://doi.org/10.1124/dmd.107.015560

  5. Rozman, Damjana

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  6. Ruppen, Mark E.

    1. In Vitro Metabolic Study of Temsirolimus: Preparation, Isolation, and Identification of the Metabolites
      Ping Cai, Rushung Tsao and Mark E. Ruppen
      Drug Metabolism and Disposition September 2007, 35 (9) 1554-1563; DOI: https://doi.org/10.1124/dmd.107.014746

S

  1. Saito, Hideyuki

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  2. Sakaki, Toshiyuki

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  3. Sárváry, Enikő

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  4. Satoh, Yoshiaki

    1. Absorption, Metabolism, and Excretion of [14C]Imidafenacin, a New Compound for Treatment of Overactive Bladder, After Oral Administration to Healthy Male Subjects
      Satoshi Ohmori, Masahiro Miura, Chifuyu Toriumi, Yoshiaki Satoh and Tsuyoshi Ooie
      Drug Metabolism and Disposition September 2007, 35 (9) 1624-1633; DOI: https://doi.org/10.1124/dmd.107.016030

  5. Scatina, JoAnn

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  6. Scollon, Edward J.

    1. Identification of Rat and Human Cytochrome P450 Isoforms and a Rat Serum Esterase That Metabolize the Pyrethroid Insecticides Deltamethrin and Esfenvalerate
      Stephen J. Godin, J. Allen Crow, Edward J. Scollon, Michael F. Hughes, Michael J. DeVito and Matthew K. Ross
      Drug Metabolism and Disposition September 2007, 35 (9) 1664-1671; DOI: https://doi.org/10.1124/dmd.107.015388

  7. Seo, Kyung-Ah

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  8. Shetty, Bhasker V.

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

  9. Shin, Jae-Gook

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  10. Silbert, Dagmar

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  11. Speth, John

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  12. States, J. Christopher

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

  13. Suzuki, Hiroshi

    1. Cholesterol-Lowering Effect of Ezetimibe in Uridine Diphosphate Glucuronosyltransferase 1A-Deficient (Gunn) Rats
      Takehito Yamamoto, Kousei Ito, Masashi Honma, Tappei Takada and Hiroshi Suzuki
      Drug Metabolism and Disposition September 2007, 35 (9) 1455-1458; DOI: https://doi.org/10.1124/dmd.107.015628

  14. Svensson, Craig K.

    1. Detection of Haptenated Proteins in Organotypic Human Skin Explant Cultures Exposed to Dapsone
      Sanjoy Roychowdhury, Albert E. Cram, Al Aly and Craig K. Svensson
      Drug Metabolism and Disposition September 2007, 35 (9) 1463-1465; DOI: https://doi.org/10.1124/dmd.107.015560

T

  1. Takada, Tappei

    1. Cholesterol-Lowering Effect of Ezetimibe in Uridine Diphosphate Glucuronosyltransferase 1A-Deficient (Gunn) Rats
      Takehito Yamamoto, Kousei Ito, Masashi Honma, Tappei Takada and Hiroshi Suzuki
      Drug Metabolism and Disposition September 2007, 35 (9) 1455-1458; DOI: https://doi.org/10.1124/dmd.107.015628

  2. Takata, Jiro

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  3. Talaat, Rasmy

    1. Metabolism, Excretion, and Pharmacokinetics of [14C]Tigecycline, a First-In-Class Glycylcycline Antibiotic, after Intravenous Infusion to Healthy Male Subjects
      Matthew Hoffmann, William DeMaio, Ronald A. Jordan, Rasmy Talaat, Dawn Harper, John Speth and JoAnn Scatina
      Drug Metabolism and Disposition September 2007, 35 (9) 1543-1553; DOI: https://doi.org/10.1124/dmd.107.015735

  4. Tamai, Ikumi

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

  5. Tamási, Viola

    1. Dehydroepiandrosterone Induces Human CYP2B6 through the Constitutive Androstane Receptor
      Krisztina Kőhalmy, Viola Tamási, László Kóbori, Enikő Sárváry, Jean-Marc Pascussi, Pálma Porrogi, Damjana Rozman, Russell A. Prough, Urs A. Meyer and Katalin Monostory
      Drug Metabolism and Disposition September 2007, 35 (9) 1495-1501; DOI: https://doi.org/10.1124/dmd.107.016303

  6. Tang, C.

    1. Hepatic Metabolism of MK-0457, a Potent Aurora Kinase Inhibitor: Interspecies Comparison and Role of Human Cytochrome P450 and Flavin-Containing Monooxygenase
      J. E. Ballard, T. Prueksaritanont and C. Tang
      Drug Metabolism and Disposition September 2007, 35 (9) 1447-1451; DOI: https://doi.org/10.1124/dmd.107.015438

  7. Timmer, Jens

    1. Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells
      Kilian Bartholomé, Maria Rius, Katrin Letschert, Daniela Keller, Jens Timmer and Dietrich Keppler
      Drug Metabolism and Disposition September 2007, 35 (9) 1476-1481; DOI: https://doi.org/10.1124/dmd.107.015636

  8. Toriumi, Chifuyu

    1. Absorption, Metabolism, and Excretion of [14C]Imidafenacin, a New Compound for Treatment of Overactive Bladder, After Oral Administration to Healthy Male Subjects
      Satoshi Ohmori, Masahiro Miura, Chifuyu Toriumi, Yoshiaki Satoh and Tsuyoshi Ooie
      Drug Metabolism and Disposition September 2007, 35 (9) 1624-1633; DOI: https://doi.org/10.1124/dmd.107.016030

  9. Trauner, Michael

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  10. Tsai, Che-Chung

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  11. Tsai, Tung-Hu

    1. Effect of Silibinin on the Pharmacokinetics of Pyrazinamide and Pyrazinoic Acid in Rats
      Jhy-Wen Wu and Tung-Hu Tsai
      Drug Metabolism and Disposition September 2007, 35 (9) 1603-1610; DOI: https://doi.org/10.1124/dmd.107.014894

  12. Tsao, Rushung

    1. In Vitro Metabolic Study of Temsirolimus: Preparation, Isolation, and Identification of the Metabolites
      Ping Cai, Rushung Tsao and Mark E. Ruppen
      Drug Metabolism and Disposition September 2007, 35 (9) 1554-1563; DOI: https://doi.org/10.1124/dmd.107.014746

  13. Turpeinen, Miia

    1. Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes
      Khaled Abass, Petri Reponen, Miia Turpeinen, Jorma Jalonen and Olavi Pelkonen
      Drug Metabolism and Disposition September 2007, 35 (9) 1634-1641; DOI: https://doi.org/10.1124/dmd.107.016295

U

  1. Unadkat, Jashvant D.

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  2. Urushino, Naoko

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

V

  1. Vági, Erika

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

  2. von Richter, Oliver

    1. ABCG2 (Breast Cancer Resistance Protein/Mitoxantrone Resistance-Associated Protein) ATPase Assay: A Useful Tool to Detect Drug-Transporter Interactions
      Hristos Glavinas, Emese Kis, Ákos Pál, Rita Kovács, Márton Jani, Erika Vági, Éva Molnár, Száva Bánsághi, Zoltán Kele, Tamás Janáky, György Báthori, Oliver von Richter, Gerrit-Jan Koomen and Péter Krajcsi
      Drug Metabolism and Disposition September 2007, 35 (9) 1533-1542; DOI: https://doi.org/10.1124/dmd.106.014605

W

  1. Wagner, John A.

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  2. Wagner, Martin

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  3. Wan, Yu-Jui Yvonne

    1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
      Matthew Wortham, Maciej Czerwinski, Lin He, Andrew Parkinson and Yu-Jui Yvonne Wan
      Drug Metabolism and Disposition September 2007, 35 (9) 1700-1710; DOI: https://doi.org/10.1124/dmd.107.016436

  4. Watanabe, Hiroshi

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  5. Weiss, Michael

    1. A Minimal Physiological Model of Thiopental Distribution Kinetics Based on a Multiple Indicator Approach
      Michael Weiss, Tom C. Krejcie and Michael J. Avram
      Drug Metabolism and Disposition September 2007, 35 (9) 1525-1532; DOI: https://doi.org/10.1124/dmd.106.014209

  6. Wenning, Larissa A.

    1. Metabolism and Disposition in Humans of Raltegravir (MK-0518), an Anti-AIDS Drug Targeting the Human Immunodeficiency Virus 1 Integrase Enzyme
      Kelem Kassahun, Ian McIntosh, Donghui Cui, David Hreniuk, Shelia Merschman, Kenneth Lasseter, Neal Azrolan, Marian Iwamoto, John A. Wagner and Larissa A. Wenning
      Drug Metabolism and Disposition September 2007, 35 (9) 1657-1663; DOI: https://doi.org/10.1124/dmd.107.016196

  7. Whittington, Dale

    1. Inhibition of P-glycoprotein Activity at the Primate Blood-Brain Barrier Increases the Distribution of Nelfinavir into the Brain but Not into the Cerebrospinal Fluid
      Amal Kaddoumi, Sung-Up Choi, Loren Kinman, Dale Whittington, Che-Chung Tsai, Rodney J.Y. Ho, Bradley D. Anderson and Jashvant D. Unadkat
      Drug Metabolism and Disposition September 2007, 35 (9) 1459-1462; DOI: https://doi.org/10.1124/dmd.107.016220

  8. Woo, Sukyung

    1. Interspecies Comparisons of Pharmacokinetics and Pharmacodynamics of Recombinant Human Erythropoietin
      Sukyung Woo and William J. Jusko
      Drug Metabolism and Disposition September 2007, 35 (9) 1672-1678; DOI: https://doi.org/10.1124/dmd.107.015248

  9. Wortham, Matthew

    1. Expression of Constitutive Androstane Receptor, Hepatic Nuclear Factor 4α, and P450 Oxidoreductase Genes Determines Interindividual Variability in Basal Expression and Activity of a Broad Scope of Xenobiotic Metabolism Genes in the Human Liver
      Matthew Wortham, Maciej Czerwinski, Lin He, Andrew Parkinson and Yu-Jui Yvonne Wan
      Drug Metabolism and Disposition September 2007, 35 (9) 1700-1710; DOI: https://doi.org/10.1124/dmd.107.016436

  10. Wu, Ellen Y.

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

  11. Wu, Jhy-Wen

    1. Effect of Silibinin on the Pharmacokinetics of Pyrazinamide and Pyrazinoic Acid in Rats
      Jhy-Wen Wu and Tung-Hu Tsai
      Drug Metabolism and Disposition September 2007, 35 (9) 1603-1610; DOI: https://doi.org/10.1124/dmd.107.014894

X

  1. Xia, Jun

    1. Subcellular Trafficking Signals of Constitutive Androstane Receptor: Evidence for a Nuclear Export Signal in the DNA-Binding Domain
      Jun Xia and Byron Kemper
      Drug Metabolism and Disposition September 2007, 35 (9) 1489-1494; DOI: https://doi.org/10.1124/dmd.107.016493

Y

  1. Yamamoto, Keiko

    1. Kinetic Studies of 25-Hydroxy-19-nor-vitamin D3 and 1α,25-Dihydroxy-19-nor-vitamin D3 Hydroxylation by CYP27B1 and CYP24A1
      Naoko Urushino, Sachie Nakabayashi, Midori A. Arai, Atsushi Kittaka, Tai C. Chen, Keiko Yamamoto, Keiko Hayashi, Shigeaki Kato, Miho Ohta, Masaki Kamakura, Shinichi Ikushiro and Toshiyuki Sakaki
      Drug Metabolism and Disposition September 2007, 35 (9) 1482-1488; DOI: https://doi.org/10.1124/dmd.107.015602

  2. Yamamoto, Takehito

    1. Cholesterol-Lowering Effect of Ezetimibe in Uridine Diphosphate Glucuronosyltransferase 1A-Deficient (Gunn) Rats
      Takehito Yamamoto, Kousei Ito, Masashi Honma, Tappei Takada and Hiroshi Suzuki
      Drug Metabolism and Disposition September 2007, 35 (9) 1455-1458; DOI: https://doi.org/10.1124/dmd.107.015628

  3. Yamamoto, Yoshio

    1. Decrease in Plasma Concentrations of Antiangiogenic Agent TSU-68 ((Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid) during Oral Administration Twice a Day to Rats
      Ryuichi Kitamura, Yoshio Yamamoto, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition September 2007, 35 (9) 1611-1616; DOI: https://doi.org/10.1124/dmd.106.014068

  4. Yamanaka, Hiroyuki

    1. Glucuronidation of Thyroxine in Human Liver, Jejunum, and Kidney Microsomes
      Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1642-1648; DOI: https://doi.org/10.1124/dmd.107.016097
    2. Stereoselective Glucuronidation of 5-(4′-Hydroxyphenyl)-5-phenylhydantoin by Human UDP-Glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: Effects of UGT-UGT Interactions
      Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1679-1686; DOI: https://doi.org/10.1124/dmd.107.015909

  5. Yamazoe, Yasushi

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

  6. Yao, Xinsheng

    1. Isolation and Identification of Phase 1 Metabolites of Demethoxycurcumin in Rats
      Yongchi Zeng, Feng Qiu, Yuan Liu, Gexia Qu and Xinsheng Yao
      Drug Metabolism and Disposition September 2007, 35 (9) 1564-1573; DOI: https://doi.org/10.1124/dmd.107.015008

  7. Yokoi, Tsuyoshi

    1. Glucuronidation of Thyroxine in Human Liver, Jejunum, and Kidney Microsomes
      Hiroyuki Yamanaka, Miki Nakajima, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1642-1648; DOI: https://doi.org/10.1124/dmd.107.016097
    2. Stereoselective Glucuronidation of 5-(4′-Hydroxyphenyl)-5-phenylhydantoin by Human UDP-Glucuronosyltransferase (UGT) 1A1, UGT1A9, and UGT2B15: Effects of UGT-UGT Interactions
      Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara, Miki Katoh and Tsuyoshi Yokoi
      Drug Metabolism and Disposition September 2007, 35 (9) 1679-1686; DOI: https://doi.org/10.1124/dmd.107.015909

  8. Yokoo, Koji

    1. Involvement of Up-Regulation of Hepatic Breast Cancer Resistance Protein in Decreased Plasma Concentration of 7-Ethyl-10-hydroxycamptothecin (SN-38) by Coadministration of S-1 in Rats
      Koji Yokoo, Akinobu Hamada, Hiroshi Watanabe, Takanobu Matsuzaki, Tomoyuki Imai, Hiromi Fujimoto, Kengo Masa, Teruko Imai and Hideyuki Saito
      Drug Metabolism and Disposition September 2007, 35 (9) 1511-1517; DOI: https://doi.org/10.1124/dmd.107.015164

  9. Yoon, Yune-Jung

    1. Characterization of Benidipine and Its Enantiomers' Metabolism by Human Liver Cytochrome P450 Enzymes
      Yune-Jung Yoon, Kwon-Bok Kim, Hyunmi Kim, Kyung-Ah Seo, Ho-Sook Kim, In-June Cha, Eun-Young Kim, Kwang-Hyeon Liu and Jae-Gook Shin
      Drug Metabolism and Disposition September 2007, 35 (9) 1518-1524; DOI: https://doi.org/10.1124/dmd.106.013607

  10. Yoshida, Miyako

    1. Preparation and In Vivo Evaluation of a Water-Soluble Prodrug for 2R-γ-Tocotrienol and as a Two-Step Prodrug for 2,7,8-Trimethyl-2S-(β-carboxyethyl)-6-hydroxychroman (S-γ-CEHC) in Rat
      Nami Akaho, Jiro Takata, Takeshi Fukushima, Kazuhisa Matsunaga, Akihiro Hattori, Ryoji Hidaka, Kosuke Fukui, Miyako Yoshida, Toshihiro Fujioka, Yoshiharu Karube and Kazuhiro Imai
      Drug Metabolism and Disposition September 2007, 35 (9) 1502-1510; DOI: https://doi.org/10.1124/dmd.106.014365

  11. Yotsumoto, Takafumi

    1. Effect of Pregnane X Receptor Ligand on Pharmacokinetics of Substrates of Organic Cation Transporter Oct1 in Rats
      Tomoji Maeda, Masanobu Oyabu, Takafumi Yotsumoto, Ryunosuke Higashi, Kiyoshi Nagata, Yasushi Yamazoe and Ikumi Tamai
      Drug Metabolism and Disposition September 2007, 35 (9) 1580-1586; DOI: https://doi.org/10.1124/dmd.107.015842

Z

  1. Zatloukal, Kurt

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610

  2. Zeng, Yongchi

    1. Isolation and Identification of Phase 1 Metabolites of Demethoxycurcumin in Rats
      Yongchi Zeng, Feng Qiu, Yuan Liu, Gexia Qu and Xinsheng Yao
      Drug Metabolism and Disposition September 2007, 35 (9) 1564-1573; DOI: https://doi.org/10.1124/dmd.107.015008

  3. Zhang, Jin

    1. Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine
      Qing-Yu Zhang, Laurence S. Kaminsky, Deborah Dunbar, Jin Zhang and Xinxin Ding
      Drug Metabolism and Disposition September 2007, 35 (9) 1617-1623; DOI: https://doi.org/10.1124/dmd.107.016543

  4. Zhang, Qing-Yu

    1. Role of Small Intestinal Cytochromes P450 in the Bioavailability of Oral Nifedipine
      Qing-Yu Zhang, Laurence S. Kaminsky, Deborah Dunbar, Jin Zhang and Xinxin Ding
      Drug Metabolism and Disposition September 2007, 35 (9) 1617-1623; DOI: https://doi.org/10.1124/dmd.107.016543

  5. Zhang, Xiaoyan

    1. Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
      Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker and David W. Hein
      Drug Metabolism and Disposition September 2007, 35 (9) 1649-1656; DOI: https://doi.org/10.1124/dmd.107.016485

  6. Zhao, Ping

    1. Evaluation of Capravirine as a CYP3A Probe Substrate: In Vitro and in Vivo Metabolism of Capravirine in Rats and Dogs
      Hai-Zhi Bu, Ping Zhao, Ping Kang, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty
      Drug Metabolism and Disposition September 2007, 35 (9) 1593-1602; DOI: https://doi.org/10.1124/dmd.107.016147

  7. Zollner, Gernot

    1. Hepatobiliary Transporter Expression in Intercellular Adhesion Molecule 1 Knockout and Fas Receptor-Deficient Mice after Common Bile Duct Ligation Is Independent of the Degree of Inflammation and Oxidative Stress
      Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, Dagmar Silbert, Andrea Fuchsbichler, Jaspreet S. Gujral, Kurt Zatloukal, Helmut Denk, Hartmut Jaeschke and Michael Trauner
      Drug Metabolism and Disposition September 2007, 35 (9) 1694-1699; DOI: https://doi.org/10.1124/dmd.107.015610
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