Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

January 01, 2008; Volume 36,Issue 1

Centennial Perspective

  • You have access
    The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 1, 1909–1958
    Patrick J. Murphy
    Drug Metabolism and Disposition January 2008, 36 (1) 1-5; DOI: https://doi.org/10.1124/dmd.107.017079

Short Communications

  • You have access
    Oseltamivir (Tamiflu) Efflux Transport at the Blood-Brain Barrier via P-Glycoprotein
    Kaori Morimoto, Masanori Nakakariya, Yoshiyuki Shirasaka, Chihaya Kakinuma, Takuya Fujita, Ikumi Tamai and Takuo Ogihara
    Drug Metabolism and Disposition January 2008, 36 (1) 6-9; DOI: https://doi.org/10.1124/dmd.107.017699
  • You have access
    The Effects of ABCB1 3′-Untranslated Region Variants on mRNA Stability
    Jason M. Gow, Leslie W. Chinn and Deanna L. Kroetz
    Drug Metabolism and Disposition January 2008, 36 (1) 10-15; DOI: https://doi.org/10.1124/dmd.107.017087

Articles

  • You have access
    Gender Differences in mRNA Expression of ATP-Binding Cassette Efflux and Bile Acid Transporters in Kidney, Liver, and Intestine of 5/6 Nephrectomized Rats
    Hong Lu and Curtis Klaassen
    Drug Metabolism and Disposition January 2008, 36 (1) 16-23; DOI: https://doi.org/10.1124/dmd.107.014845
  • You have access
    Disposition and Metabolism of [14C]Brasofensine in Rats, Monkeys, and Humans
    Mingshe Zhu, Daisy B. Whigan, Shu Y. Chang and Randy C. Dockens
    Drug Metabolism and Disposition January 2008, 36 (1) 24-35; DOI: https://doi.org/10.1124/dmd.107.016139
  • You have access
    Pharmacokinetics and Metabolism of 14C-Brivaracetam, a Novel SV2A Ligand, in Healthy Subjects
    Maria Laura Sargentini-Maier, Pascal Espié, Alain Coquette and Armel Stockis
    Drug Metabolism and Disposition January 2008, 36 (1) 36-45; DOI: https://doi.org/10.1124/dmd.107.017129
  • You have access
    Glucuronidation of Mycophenolic Acid by Wistar and Mrp2-Deficient TR- Rat Liver Microsomes
    Ian S. Westley, Raymond G. Morris, Allan M. Evans and Benedetta C. Sallustio
    Drug Metabolism and Disposition January 2008, 36 (1) 46-50; DOI: https://doi.org/10.1124/dmd.107.017210
  • You have access
    Hepatic UDP-Glucuronosyltransferases Responsible for Glucuronidation of Thyroxine in Humans
    Yoshihisa Kato, Shin-ichi Ikushiro, Yoshikazu Emi, Sekihiro Tamaki, Hiroshi Suzuki, Toshiyuki Sakaki, Shizuo Yamada and Masakuni Degawa
    Drug Metabolism and Disposition January 2008, 36 (1) 51-55; DOI: https://doi.org/10.1124/dmd.107.018184
  • You have access
    Regulation of CYP2A6 Protein Expression by Skatole, Indole, and Testicular Steroids in Primary Cultured Pig Hepatocytes
    Gang Chen, Rebecca-Ayme Cue, Kerstin Lundstrom, Jeffrey D. Wood and Olena Doran
    Drug Metabolism and Disposition January 2008, 36 (1) 56-60; DOI: https://doi.org/10.1124/dmd.107.017285
  • You have access
    Multidrug Resistance-Associated Protein 2 Is Primarily Responsible for the Biliary Excretion of Fexofenadine in Mice
    Xianbin Tian, Maciej J. Zamek-Gliszczynski, Jun Li, Arlene S. Bridges, Ken-ichi Nezasa, Nita J. Patel, Thomas J. Raub and Kim L. R. Brouwer
    Drug Metabolism and Disposition January 2008, 36 (1) 61-64; DOI: https://doi.org/10.1124/dmd.107.017319
  • You have access
    Pharmacokinetics and Metabolic Profile of Free, Conjugated, and Total Silymarin Flavonolignans in Human Plasma after Oral Administration of Milk Thistle Extract
    Zhiming Wen, Todd E. Dumas, Sarah J. Schrieber, Roy L. Hawke, Michael W. Fried and Philip C. Smith
    Drug Metabolism and Disposition January 2008, 36 (1) 65-72; DOI: https://doi.org/10.1124/dmd.107.017566
  • You have access
    Trimethoprim and the CYP2C8*3 Allele Have Opposite Effects on the Pharmacokinetics of Pioglitazone
    Aleksi Tornio, Mikko Niemi, Pertti J. Neuvonen and Janne T. Backman
    Drug Metabolism and Disposition January 2008, 36 (1) 73-80; DOI: https://doi.org/10.1124/dmd.107.018010
  • You have access
    Subdomain IIIA of Dog Albumin Contains a Binding Site Similar to Site II of Human Albumin
    Ken-ichi Kaneko, Hikaru Fukuda, Victor Tuan Giam Chuang, Keishi Yamasaki, Kohichi Kawahara, Hitoshi Nakayama, Ayaka Suenaga, Toru Maruyama and Masaki Otagiri
    Drug Metabolism and Disposition January 2008, 36 (1) 81-86; DOI: https://doi.org/10.1124/dmd.107.016873
  • You have access
    Investigation of Regional Mechanisms Responsible for Poor Oral Absorption in Humans of a Modified Release Preparation of the α-Adrenoreceptor Antagonist, 4-Amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): The Rational Use of ex Vivo Intestine to Predict in Vivo Absorption
    A. Collett, R. H. Stephens, M. D. Harwood, M. Humphrey, L. Dallman, J. Bennett, J. Davis, G. L. Carlson and G. Warhurst
    Drug Metabolism and Disposition January 2008, 36 (1) 87-94; DOI: https://doi.org/10.1124/dmd.107.016865
  • You have access
    Regulation of Hepatic Drug-Metabolizing Enzyme Genes by Toll-Like Receptor 4 Signaling Is Independent of Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein
    Romi Ghose, Damara White, Tao Guo, Jesus Vallejo and Saul J. Karpen
    Drug Metabolism and Disposition January 2008, 36 (1) 95-101; DOI: https://doi.org/10.1124/dmd.107.018051
  • You have access
    Permeability, Transport, and Metabolism of Solutes in Caco-2 Cell Monolayers: A Theoretical Study
    Huadong Sun and K. Sandy Pang
    Drug Metabolism and Disposition January 2008, 36 (1) 102-123; DOI: https://doi.org/10.1124/dmd.107.015321
  • You have access
    Effects of Chronic Renal Failure on Liver Drug Transporters
    Judith Naud, Josée Michaud, Francois A. Leblond, Stéphane Lefrancois, Alain Bonnardeaux and Vincent Pichette
    Drug Metabolism and Disposition January 2008, 36 (1) 124-128; DOI: https://doi.org/10.1124/dmd.107.018192
  • You have access
    Effect of Resveratrol on 17β-Estradiol Sulfation by Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
    Anna M. Furimsky, Carol E. Green, Lewanne E. Hunt Sharp, Paul Catz, Araba A. Adjei, Toufan Parman, Izet M. Kapetanovic, Richard M. Weinshilboum and Lalitha V. Iyer
    Drug Metabolism and Disposition January 2008, 36 (1) 129-136; DOI: https://doi.org/10.1124/dmd.107.016725
  • You have access
    HepaRG Cells as an in Vitro Model for Evaluation of Cytochrome P450 Induction in Humans
    Kajsa P. Kanebratt and Tommy B. Andersson
    Drug Metabolism and Disposition January 2008, 36 (1) 137-145; DOI: https://doi.org/10.1124/dmd.107.017418
  • You have access
    The Influence of CYP3A5 Expression on the Extent of Hepatic CYP3A Inhibition Is Substrate-Dependent: An in Vitro-in Vivo Evaluation
    Nina Isoherranen, Shana R. Ludington, Raymond C. Givens, Jatinder K. Lamba, Susan N. Pusek, E. Claire Dees, David K. Blough, Kazunori Iwanaga, Roy L. Hawke, Erin G. Schuetz, Paul B. Watkins, Kenneth E. Thummel and Mary F. Paine
    Drug Metabolism and Disposition January 2008, 36 (1) 146-154; DOI: https://doi.org/10.1124/dmd.107.018382
  • You have access
    Mechanism-Based Inactivation of Lung-Selective Cytochrome P450 CYP2F Enzymes
    Jaya S. Kartha and Garold S. Yost
    Drug Metabolism and Disposition January 2008, 36 (1) 155-162; DOI: https://doi.org/10.1124/dmd.107.017897
  • You have access
    Identification of Cytochrome P450 Enzymes Involved in the Metabolism of the New Designer Drug 4′-Methyl-α-pyrrolidinobutyrophenone
    Frank T. Peters, Markus R. Meyer, Denis S. Theobald and Hans H. Maurer
    Drug Metabolism and Disposition January 2008, 36 (1) 163-168; DOI: https://doi.org/10.1124/dmd.107.017293
  • You have access
    Novel Single Nucleotide Polymorphisms in the Promoter and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression
    Jatinder Lamba, Vishal Lamba, Stephen Strom, Raman Venkataramanan and Erin Schuetz
    Drug Metabolism and Disposition January 2008, 36 (1) 169-181; DOI: https://doi.org/10.1124/dmd.107.016600
  • You have access
    Transcription Factor and Drug-Metabolizing Enzyme Gene Expression in Lymphocytes from Healthy Human Subjects
    Gérard Siest, Elise Jeannesson, Jean-Brice Marteau, Anastasia Samara, Bérangère Marie, Michèle Pfister and Sophie Visvikis-Siest
    Drug Metabolism and Disposition January 2008, 36 (1) 182-189; DOI: https://doi.org/10.1124/dmd.107.017228
  • You have access
    Transport and Metabolism of Ferulic Acid through the Colonic Epithelium
    Laure Poquet, Michael N. Clifford and Gary Williamson
    Drug Metabolism and Disposition January 2008, 36 (1) 190-197; DOI: https://doi.org/10.1124/dmd.107.017558
  • You have access
    Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in Freshly Isolated Rat Hepatocytes
    Daniel A. J. Bow, Jennifer L. Perry, David S. Miller, John B. Pritchard and Kim L. R. Brouwer
    Drug Metabolism and Disposition January 2008, 36 (1) 198-202; DOI: https://doi.org/10.1124/dmd.107.018200

Erratum

  • You have access
    CORRECTION TO “USE OF ISOLATED HEPATOCYTE PREPARATIONS FOR CYTOCHROME P450 INHIBITION STUDIES: COMPARISON WITH MICROSOMES FOR KI DETERMINATION”
    Drug Metabolism and Disposition January 2008, 36 (1) 203; DOI: https://doi.org/10.1124/dmd.36.1.203
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition: 36 (1)
Drug Metabolism and Disposition
Vol. 36, Issue 1
1 Jan 2008
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Centennial Perspective
  • Short Communications
  • Articles
  • Erratum
  • Most Cited
  • Most Read
Loading
  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics