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Index by author

October 01, 2008; Volume 36,Issue 10

A

  1. Albayati, Zaineb A. Fadhel

    1. Pharmacokinetics of the Novel Nicotinic Receptor Antagonist N,N′-Dodecane-1,12-diyl-bis-3-picolinium Dibromide in the Rat
      Zaineb A. Fadhel Albayati, Linda P. Dwoskin and Peter A. Crooks
      Drug Metabolism and Disposition October 2008, 36 (10) 2024-2029; DOI: https://doi.org/10.1124/dmd.108.020354

  2. Aoyama, Kazunobu

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  3. Averill-Bates, Diana A.

    1. Metabolic Activity of Cytochrome P450 Isoforms in Hepatocytes Cryopreserved with Wheat Protein Extract
      Mélanie Grondin, Francine Hamel, Fathey Sarhan and Diana A. Averill-Bates
      Drug Metabolism and Disposition October 2008, 36 (10) 2121-2129; DOI: https://doi.org/10.1124/dmd.108.021162

B

  1. Bandiera, Stelvio M.

    1. Identification of Human Hepatic Cytochrome P450 Enzymes Involved in the Biotransformation of Cholic and Chenodeoxycholic Acid
      Anand K. Deo and Stelvio M. Bandiera
      Drug Metabolism and Disposition October 2008, 36 (10) 1983-1991; DOI: https://doi.org/10.1124/dmd.108.022194

  2. Brockmöller, Jürgen

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  3. Brouwer, Kenneth R.

    1. Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes
      Kristina K. Wolf, Kenneth R. Brouwer, Gary M. Pollack and Kim L. R. Brouwer
      Drug Metabolism and Disposition October 2008, 36 (10) 2086-2092; DOI: https://doi.org/10.1124/dmd.108.020842

  4. Brouwer, Kim L. R.

    1. Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes
      Kristina K. Wolf, Kenneth R. Brouwer, Gary M. Pollack and Kim L. R. Brouwer
      Drug Metabolism and Disposition October 2008, 36 (10) 2086-2092; DOI: https://doi.org/10.1124/dmd.108.020842

C

  1. Cao, Hongmei

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

  2. Chen, Weichao

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  3. Chishu, Takuya

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  4. Crooks, Peter A.

    1. Pharmacokinetics of the Novel Nicotinic Receptor Antagonist N,N′-Dodecane-1,12-diyl-bis-3-picolinium Dibromide in the Rat
      Zaineb A. Fadhel Albayati, Linda P. Dwoskin and Peter A. Crooks
      Drug Metabolism and Disposition October 2008, 36 (10) 2024-2029; DOI: https://doi.org/10.1124/dmd.108.020354

D

  1. Dalvie, Deepak

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  2. Deguchi, Yoshiharu

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

  3. Deo, Anand K.

    1. Identification of Human Hepatic Cytochrome P450 Enzymes Involved in the Biotransformation of Cholic and Chenodeoxycholic Acid
      Anand K. Deo and Stelvio M. Bandiera
      Drug Metabolism and Disposition October 2008, 36 (10) 1983-1991; DOI: https://doi.org/10.1124/dmd.108.022194

  4. DeVoss, James J.

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  5. Dickmann, Leslie J.

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  6. Dopp, John M.

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  7. Dwoskin, Linda P.

    1. Pharmacokinetics of the Novel Nicotinic Receptor Antagonist N,N′-Dodecane-1,12-diyl-bis-3-picolinium Dibromide in the Rat
      Zaineb A. Fadhel Albayati, Linda P. Dwoskin and Peter A. Crooks
      Drug Metabolism and Disposition October 2008, 36 (10) 2024-2029; DOI: https://doi.org/10.1124/dmd.108.020354

G

  1. Gao, Hua

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  2. Gillam, Elizabeth M. J.

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  3. Gödtel-Armbrust, Ute

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  4. Grondin, Mélanie

    1. Metabolic Activity of Cytochrome P450 Isoforms in Hepatocytes Cryopreserved with Wheat Protein Extract
      Mélanie Grondin, Francine Hamel, Fathey Sarhan and Diana A. Averill-Bates
      Drug Metabolism and Disposition October 2008, 36 (10) 2121-2129; DOI: https://doi.org/10.1124/dmd.108.021162

  5. Guo, Jian

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

  6. Guo, Wenchang

    1. Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Relevance for Toxicity and Mechanism of Action
      Wenchang Guo, Philip Reigan, David Siegel and David Ross
      Drug Metabolism and Disposition October 2008, 36 (10) 2050-2057; DOI: https://doi.org/10.1124/dmd.108.022004

H

  1. Hamel, Francine

    1. Metabolic Activity of Cytochrome P450 Isoforms in Hepatocytes Cryopreserved with Wheat Protein Extract
      Mélanie Grondin, Francine Hamel, Fathey Sarhan and Diana A. Averill-Bates
      Drug Metabolism and Disposition October 2008, 36 (10) 2121-2129; DOI: https://doi.org/10.1124/dmd.108.021162

  2. Hammarlund-Udenaes, Margareta

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

  3. Hanada, Kazuhiko

    1. Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats
      Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara and Hiroyasu Ogata
      Drug Metabolism and Disposition October 2008, 36 (10) 2037-2042; DOI: https://doi.org/10.1124/dmd.107.020339

  4. Hattori, Asami

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

  5. Huse, Klaus

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

I

  1. Ikemi, Yasutaka

    1. Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats
      Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara and Hiroyasu Ogata
      Drug Metabolism and Disposition October 2008, 36 (10) 2037-2042; DOI: https://doi.org/10.1124/dmd.107.020339

J

  1. Jackson, Nancy M.

    1. Suppression of CYP2B Induction by Alendronate-Mediated Farnesyl Diphosphate Synthase Inhibition in Primary Cultured Rat Hepatocytes
      Nancy M. Jackson and Thomas A. Kocarek
      Drug Metabolism and Disposition October 2008, 36 (10) 2030-2036; DOI: https://doi.org/10.1124/dmd.108.022558

  2. Johnson, Kim

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  3. Johnson, Kim A.

    1. CYP2C8- and CYP3A-Mediated C-Demethylation of (3-{[(4-tert-Butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and Liquid Chromatography/Mass Spectrometry-Nuclear Magnetic Resonance
      Chandra Prakash, Weiwei Wang, Thomas O'Connell and Kim A. Johnson
      Drug Metabolism and Disposition October 2008, 36 (10) 2093-2103; DOI: https://doi.org/10.1124/dmd.108.022897

K

  1. Kang, Young-Sook

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  2. Kapelyukh, Yury

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

  3. Kassner, Nina

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  4. Khmelnitsky, Yuri L.

    1. Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds: Synthesis of 32-Hydroxy-rifalazil
      Vadim V. Mozhaev, Lyudmila V. Mozhaeva, Peter C. Michels and Yuri L. Khmelnitsky
      Drug Metabolism and Disposition October 2008, 36 (10) 1998-2004; DOI: https://doi.org/10.1124/dmd.108.021832

  5. Kitamura, Satoshi

    1. Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin
      Satoshi Kitamura, Kazuya Maeda, Yi Wang and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2008, 36 (10) 2014-2023; DOI: https://doi.org/10.1124/dmd.108.021410

  6. Klein, Kathrin

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  7. Kocarek, Thomas A.

    1. Suppression of CYP2B Induction by Alendronate-Mediated Farnesyl Diphosphate Synthase Inhibition in Primary Cultured Rat Hepatocytes
      Nancy M. Jackson and Thomas A. Kocarek
      Drug Metabolism and Disposition October 2008, 36 (10) 2030-2036; DOI: https://doi.org/10.1124/dmd.108.022558

  8. Kose, Noriko

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  9. Kukita, Kazutaka

    1. Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats
      Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara and Hiroyasu Ogata
      Drug Metabolism and Disposition October 2008, 36 (10) 2037-2042; DOI: https://doi.org/10.1124/dmd.107.020339

L

  1. Lin, Jing

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  2. Liu, Ang

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

  3. Luo, Yan

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

M

  1. Maeda, Kazuya

    1. Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin
      Satoshi Kitamura, Kazuya Maeda, Yi Wang and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2008, 36 (10) 2014-2023; DOI: https://doi.org/10.1124/dmd.108.021410

  2. Maréchal, Jean-Didier

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

  3. Martin, Hans-Jörg

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  4. Maser, Edmund

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  5. Mathieu, Heather W.

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  6. Matovic, Nicholas

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  7. Matsubara, Tsutomu

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  8. Maurer, Tristan S.

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  9. Meineke, Ingolf

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  10. Metzger, Annegret

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  11. Michels, Peter C.

    1. Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds: Synthesis of 32-Hydroxy-rifalazil
      Vadim V. Mozhaev, Lyudmila V. Mozhaeva, Peter C. Michels and Yuri L. Khmelnitsky
      Drug Metabolism and Disposition October 2008, 36 (10) 1998-2004; DOI: https://doi.org/10.1124/dmd.108.021832

  12. Mihara, Kiyoshi

    1. Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats
      Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara and Hiroyasu Ogata
      Drug Metabolism and Disposition October 2008, 36 (10) 2037-2042; DOI: https://doi.org/10.1124/dmd.107.020339

  13. Mishra, Jayshree

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  14. Moran, John

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  15. Mozhaev, Vadim V.

    1. Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds: Synthesis of 32-Hydroxy-rifalazil
      Vadim V. Mozhaev, Lyudmila V. Mozhaeva, Peter C. Michels and Yuri L. Khmelnitsky
      Drug Metabolism and Disposition October 2008, 36 (10) 1998-2004; DOI: https://doi.org/10.1124/dmd.108.021832

  16. Mozhaeva, Lyudmila V.

    1. Extractive Biotransformation for Production of Metabolites of Poorly Soluble Compounds: Synthesis of 32-Hydroxy-rifalazil
      Vadim V. Mozhaev, Lyudmila V. Mozhaeva, Peter C. Michels and Yuri L. Khmelnitsky
      Drug Metabolism and Disposition October 2008, 36 (10) 1998-2004; DOI: https://doi.org/10.1124/dmd.108.021832

  17. Murphy, Patrick J.

    1. The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 3, 1984–2008
      Patrick J. Murphy
      Drug Metabolism and Disposition October 2008, 36 (10) 1977-1982; DOI: https://doi.org/10.1124/dmd.108.023226

N

  1. Nagata, Kiyoshi

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  2. Nakashima, Emi

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  3. Neudeck, Brien L.

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  4. Nishimura, Tomohiro

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

O

  1. O'Connell, Thomas

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277
    2. CYP2C8- and CYP3A-Mediated C-Demethylation of (3-{[(4-tert-Butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and Liquid Chromatography/Mass Spectrometry-Nuclear Magnetic Resonance
      Chandra Prakash, Weiwei Wang, Thomas O'Connell and Kim A. Johnson
      Drug Metabolism and Disposition October 2008, 36 (10) 2093-2103; DOI: https://doi.org/10.1124/dmd.108.022897

  2. Ogata, Hiroyasu

    1. Stereoselective First-Pass Metabolism of Verapamil in the Small Intestine and Liver in Rats
      Kazuhiko Hanada, Yasutaka Ikemi, Kazutaka Kukita, Kiyoshi Mihara and Hiroyasu Ogata
      Drug Metabolism and Disposition October 2008, 36 (10) 2037-2042; DOI: https://doi.org/10.1124/dmd.107.020339

  3. Okura, Takashi

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

P

  1. Paine, Mark J. I.

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

  2. Pezzuto, John M.

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

  3. Pfaar, Ulrike

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  4. Pollack, Gary M.

    1. Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes
      Kristina K. Wolf, Kenneth R. Brouwer, Gary M. Pollack and Kim L. R. Brouwer
      Drug Metabolism and Disposition October 2008, 36 (10) 2086-2092; DOI: https://doi.org/10.1124/dmd.108.020842

  5. Potchoiba, Michael

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  6. Prakash, Chandra

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277
    2. CYP2C8- and CYP3A-Mediated C-Demethylation of (3-{[(4-tert-Butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and Liquid Chromatography/Mass Spectrometry-Nuclear Magnetic Resonance
      Chandra Prakash, Weiwei Wang, Thomas O'Connell and Kim A. Johnson
      Drug Metabolism and Disposition October 2008, 36 (10) 2093-2103; DOI: https://doi.org/10.1124/dmd.108.022897

R

  1. Reigan, Philip

    1. Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Relevance for Toxicity and Mechanism of Action
      Wenchang Guo, Philip Reigan, David Siegel and David Ross
      Drug Metabolism and Disposition October 2008, 36 (10) 2050-2057; DOI: https://doi.org/10.1124/dmd.108.022004

  2. Rettie, Allan E.

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  3. Roberts, Gordon C. K.

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

  4. Ross, David

    1. Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Relevance for Toxicity and Mechanism of Action
      Wenchang Guo, Philip Reigan, David Siegel and David Ross
      Drug Metabolism and Disposition October 2008, 36 (10) 2050-2057; DOI: https://doi.org/10.1124/dmd.108.022004

  5. Rosson, Jessica L.

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  6. Rossulek, Michelle

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  7. Ruggeri, Roger B.

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

S

  1. Sai, Yoshimichi

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  2. Sarhan, Fathey

    1. Metabolic Activity of Cytochrome P450 Isoforms in Hepatocytes Cryopreserved with Wheat Protein Extract
      Mélanie Grondin, Francine Hamel, Fathey Sarhan and Diana A. Averill-Bates
      Drug Metabolism and Disposition October 2008, 36 (10) 2121-2129; DOI: https://doi.org/10.1124/dmd.108.021162

  3. Sato, Kazuko

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  4. Sato, Takenori

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

  5. Schran, Horst

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  6. Schweitzer, Alain

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  7. Scott, Dennis O.

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  8. Seki, Yoshiaki

    1. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  9. Sekiya, Yuji

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  10. Siegel, David

    1. Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Relevance for Toxicity and Mechanism of Action
      Wenchang Guo, Philip Reigan, David Siegel and David Ross
      Drug Metabolism and Disposition October 2008, 36 (10) 2050-2057; DOI: https://doi.org/10.1124/dmd.108.022004

  11. Skerjanec, Andrej

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  12. Sugawara, Mika

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  13. Sugiyama, Yuichi

    1. Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin
      Satoshi Kitamura, Kazuya Maeda, Yi Wang and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2008, 36 (10) 2014-2023; DOI: https://doi.org/10.1124/dmd.108.021410

  14. Sutcliffe, Michael J.

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

T

  1. Tai, Guoying

    1. Re-engineering of CYP2C9 to Probe Acid-Base Substrate Selectivity
      Guoying Tai, Leslie J. Dickmann, Nicholas Matovic, James J. DeVoss, Elizabeth M. J. Gillam and Allan E. Rettie
      Drug Metabolism and Disposition October 2008, 36 (10) 1992-1997; DOI: https://doi.org/10.1124/dmd.108.022186

  2. Takano, Yusuke

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087

  3. Terasaki, Tetsuya

    1. Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
      Takashi Okura, Asami Hattori, Yusuke Takano, Takenori Sato, Margareta Hammarlund-Udenaes, Tetsuya Terasaki and Yoshiharu Deguchi
      Drug Metabolism and Disposition October 2008, 36 (10) 2005-2013; DOI: https://doi.org/10.1124/dmd.108.022087
    2. Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
      Tomohiro Nishimura, Yoshiaki Seki, Kazuko Sato, Takuya Chishu, Noriko Kose, Tetsuya Terasaki, Young-Sook Kang, Yoshimichi Sai and Emi Nakashima
      Drug Metabolism and Disposition October 2008, 36 (10) 2080-2085; DOI: https://doi.org/10.1124/dmd.108.021345

  4. Troutman, Matthew D.

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

V

  1. van Breemen, Richard B.

    1. Biotransformation of the Chemopreventive Agent 2′,4′,4-Trihydroxychalcone (Isoliquiritigenin) by UDP-Glucuronosyltransferases
      Jian Guo, Ang Liu, Hongmei Cao, Yan Luo, John M. Pezzuto and Richard B. van Breemen
      Drug Metabolism and Disposition October 2008, 36 (10) 2104-2112; DOI: https://doi.org/10.1124/dmd.108.021857

W

  1. Wang, Weiwei

    1. CYP2C8- and CYP3A-Mediated C-Demethylation of (3-{[(4-tert-Butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and Liquid Chromatography/Mass Spectrometry-Nuclear Magnetic Resonance
      Chandra Prakash, Weiwei Wang, Thomas O'Connell and Kim A. Johnson
      Drug Metabolism and Disposition October 2008, 36 (10) 2093-2103; DOI: https://doi.org/10.1124/dmd.108.022897

  2. Wang, Yi

    1. Involvement of Multiple Transporters in the Hepatobiliary Transport of Rosuvastatin
      Satoshi Kitamura, Kazuya Maeda, Yi Wang and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2008, 36 (10) 2014-2023; DOI: https://doi.org/10.1124/dmd.108.021410

  3. Weiss, H. Markus

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  4. Wiegand, Hansjörg

    1. Biodistribution and Plasma Protein Binding of Zoledronic Acid
      H. Markus Weiss, Ulrike Pfaar, Alain Schweitzer, Hansjörg Wiegand, Andrej Skerjanec and Horst Schran
      Drug Metabolism and Disposition October 2008, 36 (10) 2043-2049; DOI: https://doi.org/10.1124/dmd.108.021071

  5. Wojnowski, Leszek

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  6. Wolf, C. Roland

    1. Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
      Yury Kapelyukh, Mark J. I. Paine, Jean-Didier Maréchal, Michael J. Sutcliffe, C. Roland Wolf and Gordon C. K. Roberts
      Drug Metabolism and Disposition October 2008, 36 (10) 2136-2144; DOI: https://doi.org/10.1124/dmd.108.021733

  7. Wolf, Kristina K.

    1. Effect of Albumin on the Biliary Clearance of Compounds in Sandwich-Cultured Rat Hepatocytes
      Kristina K. Wolf, Kenneth R. Brouwer, Gary M. Pollack and Kim L. R. Brouwer
      Drug Metabolism and Disposition October 2008, 36 (10) 2086-2092; DOI: https://doi.org/10.1124/dmd.108.020842

Y

  1. Yamazoe, Yasushi

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

  2. Yao, Lili

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131

  3. Yoshinari, Kouichi

    1. Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo
      Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata and Yasushi Yamazoe
      Drug Metabolism and Disposition October 2008, 36 (10) 2058-2063; DOI: https://doi.org/10.1124/dmd.108.021501

Z

  1. Zanger, Ulrich M.

    1. Carbonyl Reductase 1 Is a Predominant Doxorubicin Reductase in the Human Liver
      Nina Kassner, Klaus Huse, Hans-Jörg Martin, Ute Gödtel-Armbrust, Annegret Metzger, Ingolf Meineke, Jürgen Brockmöller, Kathrin Klein, Ulrich M. Zanger, Edmund Maser and Leszek Wojnowski
      Drug Metabolism and Disposition October 2008, 36 (10) 2113-2120; DOI: https://doi.org/10.1124/dmd.108.022251

  2. Zhang, Chenghong

    1. Metabolism, Pharmacokinetics, and Excretion of a Cholesteryl Ester Transfer Protein Inhibitor, Torcetrapib, in Rats, Monkeys, and Mice: Characterization of Unusual and Novel Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and 1H Nuclear Magnetic Resonance
      Chandra Prakash, Weichao Chen, Michelle Rossulek, Kim Johnson, Chenghong Zhang, Thomas O'Connell, Michael Potchoiba and Deepak Dalvie
      Drug Metabolism and Disposition October 2008, 36 (10) 2064-2079; DOI: https://doi.org/10.1124/dmd.108.022277

  3. Zhang, Qiuye

    1. Lipopolysaccharide Increases Cell Surface P-glycoprotein That Exhibits Diminished Activity in Intestinal Epithelial Cells
      Jayshree Mishra, Qiuye Zhang, Jessica L. Rosson, John Moran, John M. Dopp and Brien L. Neudeck
      Drug Metabolism and Disposition October 2008, 36 (10) 2145-2149; DOI: https://doi.org/10.1124/dmd.108.022632

  4. Zhang, Ying

    1. In Silico Modeling of Nonspecific Binding to Human Liver Microsomes
      Hua Gao, Lili Yao, Heather W. Mathieu, Ying Zhang, Tristan S. Maurer, Matthew D. Troutman, Dennis O. Scott, Roger B. Ruggeri and Jing Lin
      Drug Metabolism and Disposition October 2008, 36 (10) 2130-2135; DOI: https://doi.org/10.1124/dmd.107.020131
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