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Index by author

November 01, 2008; Volume 36,Issue 11

A

  1. Abadie, Catherine

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  2. Aboutabl, Mona E.

    1. Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats
      Beshay N. M. Zordoky, Mona E. Aboutabl and Ayman O. S. El-Kadi
      Drug Metabolism and Disposition November 2008, 36 (11) 2277-2286; DOI: https://doi.org/10.1124/dmd.108.023077

  3. Allen, Ann

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

  4. Alworth, Bill

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  5. André, François

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  6. Aninat, Caroline

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  7. Aristei, Yasmin

    1. The Molecular Basis of CYP2D6-Mediated N-Dealkylation: Balance between Metabolic Clearance Routes and Enzyme Inhibition
      Britta Bonn, Collen M. Masimirembwa, Yasmin Aristei and Ismael Zamora
      Drug Metabolism and Disposition November 2008, 36 (11) 2199-2210; DOI: https://doi.org/10.1124/dmd.108.022376

  8. Atkins, William

    1. Principal Component Analysis of CYP2C9 and CYP3A4 Probe Substrate/Inhibitor Panels
      Abhinav Nath and William Atkins
      Drug Metabolism and Disposition November 2008, 36 (11) 2151-2155; DOI: https://doi.org/10.1124/dmd.108.022061

B

  1. Bonn, Britta

    1. The Molecular Basis of CYP2D6-Mediated N-Dealkylation: Balance between Metabolic Clearance Routes and Enzyme Inhibition
      Britta Bonn, Collen M. Masimirembwa, Yasmin Aristei and Ismael Zamora
      Drug Metabolism and Disposition November 2008, 36 (11) 2199-2210; DOI: https://doi.org/10.1124/dmd.108.022376

  2. Bratton, Stacie M.

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  3. Brouwer, Kim L. R.

    1. Apparent Differences in Mechanisms of Harmol Sulfate Biliary Excretion in Mice and Rats
      Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Ken-ichi Nezasa and Kim L. R. Brouwer
      Drug Metabolism and Disposition November 2008, 36 (11) 2156-2158; DOI: https://doi.org/10.1124/dmd.108.022053
    2. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  4. Bullough, David A.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

C

  1. Cable, Edward E.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  2. Chan, Kenneth K.

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  3. Chang, Thomas K. H.

    1. Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor
      Eugene Y. H. Yeung, Tatsuya Sueyoshi, Masahiko Negishi and Thomas K. H. Chang
      Drug Metabolism and Disposition November 2008, 36 (11) 2270-2276; DOI: https://doi.org/10.1124/dmd.108.023499

  4. Chen, Weichao

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

  5. Cheng, Hao

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  6. Chow, Sylvia

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  7. Christians, Uwe

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  8. Cohen, Isaac

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  9. Cox, Loretta M.

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

D

  1. D'Agostino, Jaime

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  2. Dai, Guowei

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  3. Dalvie, Deepak

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

  4. Delaforge, Marcel

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  5. Deshmukh, Rahul

    1. Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants
      Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
      Drug Metabolism and Disposition November 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640

  6. Dever, Joseph T.

    1. l-Methionine-dl-sulfoxide Metabolism and Toxicity in Freshly Isolated Mouse Hepatocytes: Gender Differences and Inhibition with Aminooxyacetic Acid
      Joseph T. Dever and Adnan A. Elfarra
      Drug Metabolism and Disposition November 2008, 36 (11) 2252-2260; DOI: https://doi.org/10.1124/dmd.108.023390

  7. Ding, Xinxin

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

E

  1. El-Kadi, Ayman O. S.

    1. Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats
      Beshay N. M. Zordoky, Mona E. Aboutabl and Ayman O. S. El-Kadi
      Drug Metabolism and Disposition November 2008, 36 (11) 2277-2286; DOI: https://doi.org/10.1124/dmd.108.023077

  2. Elfarra, Adnan A.

    1. l-Methionine-dl-sulfoxide Metabolism and Toxicity in Freshly Isolated Mouse Hepatocytes: Gender Differences and Inhibition with Aminooxyacetic Acid
      Joseph T. Dever and Adnan A. Elfarra
      Drug Metabolism and Disposition November 2008, 36 (11) 2252-2260; DOI: https://doi.org/10.1124/dmd.108.023390

  3. Erion, Mark D.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

F

  1. Ferrero, James L.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  2. Finel, Moshe

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863
    2. The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases
      Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731
    3. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  3. Foroozesh, Maryam

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  4. Fujita, Yukiyoshi

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

  5. Fujitaki, James M.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

G

  1. Gallus-Zawada, Anna

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  2. Gao, Yang

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  3. Ge, Guang-Bo

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  4. Goh, Lin Tang

    1. Identification of Stereoisomeric Metabolites of Meisoindigo in Rat Liver Microsomes by Achiral and Chiral Liquid Chromatography/Tandem Mass Spectrometry
      Meng Huang, Lin Tang Goh and Paul C. Ho
      Drug Metabolism and Disposition November 2008, 36 (11) 2171-2184; DOI: https://doi.org/10.1124/dmd.108.021956

  5. Graham, Steven H.

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

  6. Guengerich, F. Peter

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

H

  1. Hamon, Véronique

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  2. Hawke, Roy L.

    1. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  3. Hayashi, Mike

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  4. Hayashi, Yoshio

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  5. Heyd, Bruno

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  6. Hirvonen, Jouni

    1. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  7. Ho, Paul C.

    1. Identification of Stereoisomeric Metabolites of Meisoindigo in Rat Liver Microsomes by Achiral and Chiral Liquid Chromatography/Tandem Mass Spectrometry
      Meng Huang, Lin Tang Goh and Paul C. Ho
      Drug Metabolism and Disposition November 2008, 36 (11) 2171-2184; DOI: https://doi.org/10.1124/dmd.108.021956

  8. Hoffmaster, Keith A.

    1. Apparent Differences in Mechanisms of Harmol Sulfate Biliary Excretion in Mice and Rats
      Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Ken-ichi Nezasa and Kim L. R. Brouwer
      Drug Metabolism and Disposition November 2008, 36 (11) 2156-2158; DOI: https://doi.org/10.1124/dmd.108.022053

  9. Hollenberg, Paul F.

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  10. Hollis, Frank J.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

  11. Horiuchi, Ryuya

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

  12. Hou, Jinzhao

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  13. Huang, Meng

    1. Identification of Stereoisomeric Metabolites of Meisoindigo in Rat Liver Microsomes by Achiral and Chiral Liquid Chromatography/Tandem Mass Spectrometry
      Meng Huang, Lin Tang Goh and Paul C. Ho
      Drug Metabolism and Disposition November 2008, 36 (11) 2171-2184; DOI: https://doi.org/10.1124/dmd.108.021956

  14. Hughes, Stephen C.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

I

  1. Ikushiro, Shin-ichi

    1. The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases
      Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731

  2. Inui, Ken-ichi

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  3. Itäaho, Katriina

    1. The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases
      Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731

  4. Ito, Bruce R.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

J

  1. Jung, Heung-Chae

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

K

  1. Kang, Ning

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

  2. Katsura, Toshiya

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  3. Kaukonen, Ann Marie

    1. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  4. Kent, Ute M.

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  5. Kim, Dae-Hwan

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

  6. Kim, Dong-Hyun

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

  7. Kim, Keon-Hee

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

  8. Klamerus, Megan M.

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

  9. Klisovic, Rebecca

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  10. Kupfer, René

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

L

  1. Lee, Jin Kyung

    1. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  2. Li, Wei

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  3. Lichti, Cheryl F.

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  4. Lin, Jian

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

  5. Linemeyer, David L.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  6. Ling, Guoyu

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  7. Liu, Fucai

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  8. Liu, Hong-Tao

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  9. Liu, Hui-Xin

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  10. Liu, Kwang-Hyeon

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

  11. Liu, Yong

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  12. Liu, Zhongfa

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

M

  1. Mackenzie, Peter I.

    1. The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases
      Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731

  2. Marcucci, Guido

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  3. Masimirembwa, Collen M.

    1. The Molecular Basis of CYP2D6-Mediated N-Dealkylation: Balance between Metabolic Clearance Routes and Enzyme Inhibition
      Britta Bonn, Collen M. Masimirembwa, Yasmin Aristei and Ismael Zamora
      Drug Metabolism and Disposition November 2008, 36 (11) 2199-2210; DOI: https://doi.org/10.1124/dmd.108.022376

  4. Masuda, Satohiro

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  5. Maurer, Hans H.

    1. The Role of Human Hepatic Cytochrome P450 Isozymes in the Metabolism of Racemic 3,4-Methylenedioxy-Methamphetamine and Its Enantiomers
      Markus R. Meyer, Frank T. Peters and Hans H. Maurer
      Drug Metabolism and Disposition November 2008, 36 (11) 2345-2354; DOI: https://doi.org/10.1124/dmd.108.021543

  6. Mazur, Anna

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  7. McCall, Alecia

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  8. Meyer, Markus R.

    1. The Role of Human Hepatic Cytochrome P450 Isozymes in the Metabolism of Racemic 3,4-Methylenedioxy-Methamphetamine and Its Enantiomers
      Markus R. Meyer, Frank T. Peters and Hans H. Maurer
      Drug Metabolism and Disposition November 2008, 36 (11) 2345-2354; DOI: https://doi.org/10.1124/dmd.108.021543

  9. Miller, Grover P.

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  10. Miller, Tricia M.

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

  11. Miners, John O.

    1. The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases
      Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731

  12. Miranda, Sonia R.

    1. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  13. Miyazaki, Mitsue

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

  14. Moran, Jeffery H.

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  15. Morris, Marilyn E.

    1. Effects of L-Lactate and D-Mannitol on γ-Hydroxybutyrate Toxicokinetics and Toxicodynamics in Rats
      Qi Wang, Xiaodong Wang and Marilyn E. Morris
      Drug Metabolism and Disposition November 2008, 36 (11) 2244-2251; DOI: https://doi.org/10.1124/dmd.108.022996

  16. Morrissey, Kari

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  17. Motivaras, Dimple S.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

  18. Mu, Ying

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

N

  1. Nakamura, Katsunori

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

  2. Nath, Abhinav

    1. Principal Component Analysis of CYP2C9 and CYP3A4 Probe Substrate/Inhibitor Panels
      Abhinav Nath and William Atkins
      Drug Metabolism and Disposition November 2008, 36 (11) 2151-2155; DOI: https://doi.org/10.1124/dmd.108.022061

  3. Negishi, Masahiko

    1. Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor
      Eugene Y. H. Yeung, Tatsuya Sueyoshi, Masahiko Negishi and Thomas K. H. Chang
      Drug Metabolism and Disposition November 2008, 36 (11) 2270-2276; DOI: https://doi.org/10.1124/dmd.108.023499

  4. Nezasa, Ken-ichi

    1. Apparent Differences in Mechanisms of Harmol Sulfate Biliary Excretion in Mice and Rats
      Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Ken-ichi Nezasa and Kim L. R. Brouwer
      Drug Metabolism and Disposition November 2008, 36 (11) 2156-2158; DOI: https://doi.org/10.1124/dmd.108.022053

  5. Noon, Kate

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

O

  1. Obach, R. Scott

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

P

  1. Pan, Jae-Gu

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

  2. Pan, Yvonne

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  3. Perrin, Lionel

    1. Metabolism of Phenylahistin Enantiomers by Cytochromes P450: A Possible Explanation for Their Different Cytotoxicity
      Lionel Perrin, Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Bruno Heyd, François André and Marcel Delaforge
      Drug Metabolism and Disposition November 2008, 36 (11) 2381-2392; DOI: https://doi.org/10.1124/dmd.107.019919

  4. Peters, Frank T.

    1. The Role of Human Hepatic Cytochrome P450 Isozymes in the Metabolism of Racemic 3,4-Methylenedioxy-Methamphetamine and Its Enantiomers
      Markus R. Meyer, Frank T. Peters and Hans H. Maurer
      Drug Metabolism and Disposition November 2008, 36 (11) 2345-2354; DOI: https://doi.org/10.1124/dmd.108.021543

  5. Piao, Shujuan

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

  6. Poloyac, Samuel M.

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

Q

  1. Qin, Gengyao

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

  2. Qiu, Feng

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

R

  1. Radominska-Pandya, Anna

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  2. Rohan, Lisa C.

    1. Intravenous Formulation of N-Hydroxy-N′-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for Inhibition of Rat Brain 20-Hydroxyeicosatetraenoic Acid Formation
      Ying Mu, Megan M. Klamerus, Tricia M. Miller, Lisa C. Rohan, Steven H. Graham and Samuel M. Poloyac
      Drug Metabolism and Disposition November 2008, 36 (11) 2324-2330; DOI: https://doi.org/10.1124/dmd.108.023150

  3. Rousell, Victoria M.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

S

  1. Scott, Rebecca J.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

  2. Shardlow, Peter C.

    1. Metabolism and Disposition of Fluticasone Furoate, an Enhanced-Affinity Glucocorticoid, in Humans
      Stephen C. Hughes, Peter C. Shardlow, Frank J. Hollis, Rebecca J. Scott, Dimple S. Motivaras, Ann Allen and Victoria M. Rousell
      Drug Metabolism and Disposition November 2008, 36 (11) 2337-2344; DOI: https://doi.org/10.1124/dmd.108.022137

  3. Shou, Magang

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  4. Siissalo, Sanna

    1. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  5. Sivaneri, Meena

    1. Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants
      Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
      Drug Metabolism and Disposition November 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640

  6. Skiles, Gary L.

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  7. Smith, Philip C.

    1. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  8. Smolarek, Teresa A.

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

  9. Sridar, Chitra

    1. Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether
      Chitra Sridar, Ute M. Kent, Kate Noon, Alecia McCall, Bill Alworth, Maryam Foroozesh and Paul F. Hollenberg
      Drug Metabolism and Disposition November 2008, 36 (11) 2234-2243; DOI: https://doi.org/10.1124/dmd.108.021493

  10. Staub, Richard E.

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  11. Stilgenbauer, Eric

    1. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  12. Sueyoshi, Tatsuya

    1. Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor
      Eugene Y. H. Yeung, Tatsuya Sueyoshi, Masahiko Negishi and Thomas K. H. Chang
      Drug Metabolism and Disposition November 2008, 36 (11) 2270-2276; DOI: https://doi.org/10.1124/dmd.108.023499

  13. Sun, Jie

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  14. Swanson, Leah

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  15. Szklarz, Grazyna D.

    1. Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants
      Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
      Drug Metabolism and Disposition November 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640

T

  1. Terada, Tomohiro

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  2. Tu, Youbin

    1. Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants
      Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
      Drug Metabolism and Disposition November 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640

V

  1. van Poelje, Paul D.

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  2. Vaz, Alfin D.

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

W

  1. Wang, Li-Ming

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  2. Wang, Qi

    1. Effects of L-Lactate and D-Mannitol on γ-Hydroxybutyrate Toxicokinetics and Toxicodynamics in Rats
      Qi Wang, Xiaodong Wang and Marilyn E. Morris
      Drug Metabolism and Disposition November 2008, 36 (11) 2244-2251; DOI: https://doi.org/10.1124/dmd.108.022996

  3. Wang, Suping

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  4. Wang, Xiaodong

    1. Effects of L-Lactate and D-Mannitol on γ-Hydroxybutyrate Toxicokinetics and Toxicodynamics in Rats
      Qi Wang, Xiaodong Wang and Marilyn E. Morris
      Drug Metabolism and Disposition November 2008, 36 (11) 2244-2251; DOI: https://doi.org/10.1124/dmd.108.022996

  5. Wei, Xiaohui

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  6. Wen, Zhiming

    1. Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Multidrug Resistance-Associated Protein 2 (Abcc2)
      Sonia R. Miranda, Jin Kyung Lee, Kim L. R. Brouwer, Zhiming Wen, Philip C. Smith and Roy L. Hawke
      Drug Metabolism and Disposition November 2008, 36 (11) 2219-2226; DOI: https://doi.org/10.1124/dmd.108.021790

  7. Wu, Hong

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

X

  1. Xie, Zhiliang

    1. Enzyme Kinetics of GTI-2040, a Phosphorothioate Oligonucleotide Targeting Ribonucleotide Reductase
      Xiaohui Wei, Guowei Dai, Zhongfa Liu, Hao Cheng, Zhiliang Xie, Rebecca Klisovic, Guido Marcucci and Kenneth K. Chan
      Drug Metabolism and Disposition November 2008, 36 (11) 2227-2233; DOI: https://doi.org/10.1124/dmd.108.021295

  2. Xu, Lilly

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

  3. Xu, Yang

    1. Modeling, Prediction, and in Vitro in Vivo Correlation of CYP3A4 Induction
      Magang Shou, Mike Hayashi, Yvonne Pan, Yang Xu, Kari Morrissey, Lilly Xu and Gary L. Skiles
      Drug Metabolism and Disposition November 2008, 36 (11) 2355-2370; DOI: https://doi.org/10.1124/dmd.108.020602

Y

  1. Yamamoto, Koujirou

    1. Defective Activity of Recombinant Cytochromes P450 3A4.2 and 3A4.16 in Oxidation of Midazolam, Nifedipine, and Testosterone
      Mitsue Miyazaki, Katsunori Nakamura, Yukiyoshi Fujita, F. Peter Guengerich, Ryuya Horiuchi and Koujirou Yamamoto
      Drug Metabolism and Disposition November 2008, 36 (11) 2287-2291; DOI: https://doi.org/10.1124/dmd.108.021816

  2. Yang, Chun

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  3. Yang, Ling

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  4. Yao, Xinsheng

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

  5. Yeung, Eugene Y. H.

    1. Identification of Ginkgo biloba as a Novel Activator of Pregnane X Receptor
      Eugene Y. H. Yeung, Tatsuya Sueyoshi, Masahiko Negishi and Thomas K. H. Chang
      Drug Metabolism and Disposition November 2008, 36 (11) 2270-2276; DOI: https://doi.org/10.1124/dmd.108.023499

  6. Yokoo, Sachiko

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  7. Yonezawa, Atsushi

    1. Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer
      Sachiko Yokoo, Satohiro Masuda, Atsushi Yonezawa, Tomohiro Terada, Toshiya Katsura and Ken-ichi Inui
      Drug Metabolism and Disposition November 2008, 36 (11) 2299-2306; DOI: https://doi.org/10.1124/dmd.108.023168

  8. Yun, Chul-Ho

    1. Generation of Human Metabolites of 7-Ethoxycoumarin by Bacterial Cytochrome P450 BM3
      Dong-Hyun Kim, Keon-Hee Kim, Dae-Hwan Kim, Kwang-Hyeon Liu, Heung-Chae Jung, Jae-Gu Pan and Chul-Ho Yun
      Drug Metabolism and Disposition November 2008, 36 (11) 2166-2170; DOI: https://doi.org/10.1124/dmd.108.021220

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Apparent Differences in Mechanisms of Harmol Sulfate Biliary Excretion in Mice and Rats
      Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Ken-ichi Nezasa and Kim L. R. Brouwer
      Drug Metabolism and Disposition November 2008, 36 (11) 2156-2158; DOI: https://doi.org/10.1124/dmd.108.022053

  2. Zamora, Ismael

    1. The Molecular Basis of CYP2D6-Mediated N-Dealkylation: Balance between Metabolic Clearance Routes and Enzyme Inhibition
      Britta Bonn, Collen M. Masimirembwa, Yasmin Aristei and Ismael Zamora
      Drug Metabolism and Disposition November 2008, 36 (11) 2199-2210; DOI: https://doi.org/10.1124/dmd.108.022376

  3. Zhang, Bao-Hong

    1. Preclinical Pharmacokinetics of a HepDirect Prodrug of a Novel Phosphonate-Containing Thyroid Hormone Receptor Agonist
      James M. Fujitaki, Edward E. Cable, Bruce R. Ito, Bao-Hong Zhang, Jinzhao Hou, Chun Yang, David A. Bullough, James L. Ferrero, Paul D. van Poelje, David L. Linemeyer and Mark D. Erion
      Drug Metabolism and Disposition November 2008, 36 (11) 2393-2403; DOI: https://doi.org/10.1124/dmd.108.021642

  4. Zhang, Chenghong

    1. Pharmacokinetics, Metabolism, and Excretion of Torcetrapib, a Cholesteryl Ester Transfer Protein Inhibitor, in Humans
      Deepak Dalvie, Weichao Chen, Chenghong Zhang, Alfin D. Vaz, Teresa A. Smolarek, Loretta M. Cox, Jian Lin and R. Scott Obach
      Drug Metabolism and Disposition November 2008, 36 (11) 2185-2198; DOI: https://doi.org/10.1124/dmd.108.023176

  5. Zhang, Hongbo

    1. The Expression of Most UDP-Glucuronosyltransferases (UGTs) Is Increased Significantly during Caco-2 Cell Differentiation, whereas UGT1A6 Is Highly Expressed Also in Undifferentiated Cells
      Sanna Siissalo, Hongbo Zhang, Eric Stilgenbauer, Ann Marie Kaukonen, Jouni Hirvonen and Moshe Finel
      Drug Metabolism and Disposition November 2008, 36 (11) 2331-2336; DOI: https://doi.org/10.1124/dmd.108.022335

  6. Zhang, Jiang-Wei

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  7. Zhang, Qing-Yu

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  8. Zhang, Xiuling

    1. Characterization of CYP2A13*2, a Variant Cytochrome P450 Allele Previously Found to Be Associated with Decreased Incidences of Lung Adenocarcinoma in Smokers
      Jaime D'Agostino, Xiuling Zhang, Hong Wu, Guoyu Ling, Suping Wang, Qing-Yu Zhang, Fucai Liu and Xinxin Ding
      Drug Metabolism and Disposition November 2008, 36 (11) 2316-2323; DOI: https://doi.org/10.1124/dmd.108.022822

  9. Zhang, Yan-Yan

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  10. Zhang, Yan Ling

    1. Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen β-Receptor Agonist MF101
      René Kupfer, Leah Swanson, Sylvia Chow, Richard E. Staub, Yan Ling Zhang, Isaac Cohen and Uwe Christians
      Drug Metabolism and Disposition November 2008, 36 (11) 2261-2269; DOI: https://doi.org/10.1124/dmd.108.021402

  11. Zhao, Jiu-Yang

    1. Metabolic Profiling and Cytochrome P450 Reaction Phenotyping of Medroxyprogesterone Acetate
      Jiang-Wei Zhang, Yong Liu, Jiu-Yang Zhao, Li-Ming Wang, Guang-Bo Ge, Yang Gao, Wei Li, Hong-Tao Liu, Hui-Xin Liu, Yan-Yan Zhang, Jie Sun and Ling Yang
      Drug Metabolism and Disposition November 2008, 36 (11) 2292-2298; DOI: https://doi.org/10.1124/dmd.108.022525

  12. Zhu, Zhiyong

    1. Isolation and Identification of Urinary Metabolites of Berberine in Rats and Humans
      Feng Qiu, Zhiyong Zhu, Ning Kang, Shujuan Piao, Gengyao Qin and Xinsheng Yao
      Drug Metabolism and Disposition November 2008, 36 (11) 2159-2165; DOI: https://doi.org/10.1124/dmd.108.021659

  13. Zielinska, Agnieszka K.

    1. Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine90 Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8-Hydroxywarfarin
      Grover P. Miller, Cheryl F. Lichti, Agnieszka K. Zielinska, Anna Mazur, Stacie M. Bratton, Anna Gallus-Zawada, Moshe Finel, Jeffery H. Moran and Anna Radominska-Pandya
      Drug Metabolism and Disposition November 2008, 36 (11) 2211-2218; DOI: https://doi.org/10.1124/dmd.108.022863

  14. Zordoky, Beshay N. M.

    1. Modulation of Cytochrome P450 Gene Expression and Arachidonic Acid Metabolism during Isoproterenol-Induced Cardiac Hypertrophy in Rats
      Beshay N. M. Zordoky, Mona E. Aboutabl and Ayman O. S. El-Kadi
      Drug Metabolism and Disposition November 2008, 36 (11) 2277-2286; DOI: https://doi.org/10.1124/dmd.108.023077
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