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Index by author

December 01, 2008; Volume 36,Issue 12

B

  1. Barker, David F.

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564

  2. Barter, Z. E.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

  3. Bendaly, Jean

    1. Systemic Functional Expression of N-Acetyltransferase Polymorphism in the F344 Nat2 Congenic Rat
      David W. Hein, Jean Bendaly, Jason R. Neale and Mark A. Doll
      Drug Metabolism and Disposition December 2008, 36 (12) 2452-2459; DOI: https://doi.org/10.1124/dmd.108.023960

  4. Bhide, Rajeev S.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  5. Boernsen, K.-Olaf

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  6. Boutros, Paul C.

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  7. Bruin, Gerard J. M.

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  8. Brun, Marie-Elise

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  9. Burczynski, Michael E.

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

C

  1. Celius, Trine

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  2. Chang, Shu-Ying

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  3. Cheung, Connie

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  4. Chowdry, J. E.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

  5. Christopher, Lisa J.

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

  6. Clarke, Stephen E.

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  7. Cole, Susan P. C.

    1. Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)
      Caroline E. Grant, Mian Gao, Marianne K. DeGorter, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition December 2008, 36 (12) 2571-2581; DOI: https://doi.org/10.1124/dmd.108.022491

  8. Connolly, Sandra M.

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  9. Cui, Donghui

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

D

  1. D'Esposito, Fabrizio

    1. Interindividual Variation in Relative CYP1A2/3A4 Phenotype Influences Susceptibility of Clozapine Oxidation to Cytochrome P450-Specific Inhibition in Human Hepatic Microsomes
      Wei V. Zhang, Fabrizio D'Esposito, Robert J. Edwards, Iqbal Ramzan and Michael Murray
      Drug Metabolism and Disposition December 2008, 36 (12) 2547-2555; DOI: https://doi.org/10.1124/dmd.108.023671

  2. Davis, Charles B.

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  3. Dawson, Paul A.

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  4. Deeley, Roger G.

    1. Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)
      Caroline E. Grant, Mian Gao, Marianne K. DeGorter, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition December 2008, 36 (12) 2571-2581; DOI: https://doi.org/10.1124/dmd.108.022491

  5. DeGorter, Marianne K.

    1. Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)
      Caroline E. Grant, Mian Gao, Marianne K. DeGorter, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition December 2008, 36 (12) 2571-2581; DOI: https://doi.org/10.1124/dmd.108.022491

  6. DeVore, Natasha M.

    1. Key Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A Enzymes
      Natasha M. DeVore, Brian D. Smith, Michael J. Urban and Emily E. Scott
      Drug Metabolism and Disposition December 2008, 36 (12) 2582-2590; DOI: https://doi.org/10.1124/dmd.108.023770

  7. Doll, Mark A.

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564
    2. Systemic Functional Expression of N-Acetyltransferase Polymorphism in the F344 Nat2 Congenic Rat
      David W. Hein, Jean Bendaly, Jason R. Neale and Mark A. Doll
      Drug Metabolism and Disposition December 2008, 36 (12) 2452-2459; DOI: https://doi.org/10.1124/dmd.108.023960

  8. Dumontet, C.

    1. Differential Allelic Expression in Leukoblast from Patients with Acute Myeloid Leukemia Suggests Genetic Regulation of CDA, DCK, NT5C2, NT5C3, and TP53
      L. P. Jordheim, T. Nguyen-Dumont, X. Thomas, C. Dumontet and S. V. Tavtigian
      Drug Metabolism and Disposition December 2008, 36 (12) 2419-2423; DOI: https://doi.org/10.1124/dmd.108.023184

E

  1. Edwards, Robert J.

    1. Interindividual Variation in Relative CYP1A2/3A4 Phenotype Influences Susceptibility of Clozapine Oxidation to Cytochrome P450-Specific Inhibition in Human Hepatic Microsomes
      Wei V. Zhang, Fabrizio D'Esposito, Robert J. Edwards, Iqbal Ramzan and Michael Murray
      Drug Metabolism and Disposition December 2008, 36 (12) 2547-2555; DOI: https://doi.org/10.1124/dmd.108.023671

  2. Elfarra, Adnan A.

    1. Purification and Characterization of Flavin-Containing Monooxygenase Isoform 3 from Rat Kidney Microsomes
      Rachel M. Novick and Adnan A. Elfarra
      Drug Metabolism and Disposition December 2008, 36 (12) 2468-2474; DOI: https://doi.org/10.1124/dmd.108.021436

  3. Empey, Philip E.

    1. N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into Milk
      Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition December 2008, 36 (12) 2591-2596; DOI: https://doi.org/10.1124/dmd.108.021980

F

  1. Faller, Thomas

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  2. Fardel, Olivier

    1. Activation of the Aryl Hydrocarbon Receptor by the Calcium/Calmodulin-Dependent Protein Kinase Kinase Inhibitor 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid (STO-609)
      Patricia Monteiro, David Gilot, Sophie Langouet and Olivier Fardel
      Drug Metabolism and Disposition December 2008, 36 (12) 2556-2563; DOI: https://doi.org/10.1124/dmd.108.023333

  3. Fatato, Penny

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  4. Foti, Robert S.

    1. The Combination of Chemical and Antibody Inhibitors for Superior P450 3A Inhibition in Reaction Phenotyping Studies
      Dan A. Rock, Robert S. Foti and Josh T. Pearson
      Drug Metabolism and Disposition December 2008, 36 (12) 2410-2413; DOI: https://doi.org/10.1124/dmd.108.023572

  5. Franklin, Michael R.

    1. 2-Diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) Revisited: Comparative Cytochrome P450 Inhibition in Human Liver Microsomes by SKF525A, Its Metabolites, and SKF-Acid and SKF-Alcohol
      Michael R. Franklin and Laura B. Hathaway
      Drug Metabolism and Disposition December 2008, 36 (12) 2539-2546; DOI: https://doi.org/10.1124/dmd.108.023549

  6. Funk, Christoph

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

G

  1. Gao, Mian

    1. Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)
      Caroline E. Grant, Mian Gao, Marianne K. DeGorter, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition December 2008, 36 (12) 2571-2581; DOI: https://doi.org/10.1124/dmd.108.022491

  2. Garver, Eric

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  3. Gilot, David

    1. Activation of the Aryl Hydrocarbon Receptor by the Calcium/Calmodulin-Dependent Protein Kinase Kinase Inhibitor 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid (STO-609)
      Patricia Monteiro, David Gilot, Sophie Langouet and Olivier Fardel
      Drug Metabolism and Disposition December 2008, 36 (12) 2556-2563; DOI: https://doi.org/10.1124/dmd.108.023333

  4. Gonzalez, Frank J.

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  5. Goswami, Mamta

    1. N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into Milk
      Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition December 2008, 36 (12) 2591-2596; DOI: https://doi.org/10.1124/dmd.108.021980

  6. Grant, Caroline E.

    1. Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)
      Caroline E. Grant, Mian Gao, Marianne K. DeGorter, Susan P. C. Cole and Roger G. Deeley
      Drug Metabolism and Disposition December 2008, 36 (12) 2571-2581; DOI: https://doi.org/10.1124/dmd.108.022491

  7. Grimm, Hans-Peter

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  8. Guico-Pabia, Christine

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

H

  1. Han, Chao

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  2. Harlow, J. R.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

  3. Harper, Patricia A.

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  4. Hathaway, Laura B.

    1. 2-Diethylaminoethyl-2,2-diphenylvalerate-HCl (SKF525A) Revisited: Comparative Cytochrome P450 Inhibition in Human Liver Microsomes by SKF525A, Its Metabolites, and SKF-Acid and SKF-Alcohol
      Michael R. Franklin and Laura B. Hathaway
      Drug Metabolism and Disposition December 2008, 36 (12) 2539-2546; DOI: https://doi.org/10.1124/dmd.108.023549

  5. He, Kan

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

  6. Hein, David W.

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564
    2. Systemic Functional Expression of N-Acetyltransferase Polymorphism in the F344 Nat2 Congenic Rat
      David W. Hein, Jean Bendaly, Jason R. Neale and Mark A. Doll
      Drug Metabolism and Disposition December 2008, 36 (12) 2452-2459; DOI: https://doi.org/10.1124/dmd.108.023960

  7. Hiratsuka, Masahiro

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  8. Hollis, Frank J.

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  9. Horie, Toru

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

  10. Hugger, Erin D.

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  11. Humphreys, William G.

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

I

  1. Idle, Jeffrey R.

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  2. Inoue, Tae

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

  3. Ishikawa, Masaaki

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  4. Isler, Jennifer A.

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  5. Iyer, Ramaswamy A.

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

J

  1. Jiang, Qin

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  2. Johnson, Benjamin M.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  3. Jordheim, L. P.

    1. Differential Allelic Expression in Leukoblast from Patients with Acute Myeloid Leukemia Suggests Genetic Regulation of CDA, DCK, NT5C2, NT5C3, and TP53
      L. P. Jordheim, T. Nguyen-Dumont, X. Thomas, C. Dumontet and S. V. Tavtigian
      Drug Metabolism and Disposition December 2008, 36 (12) 2419-2423; DOI: https://doi.org/10.1124/dmd.108.023184

K

  1. Kamath, Amrita V.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  2. Kansy, Manfred

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  3. Kitamura, Shigeyuki

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

  4. Krausz, Kristopher W.

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

L

  1. Lago, Michael W.

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

  2. Langouet, Sophie

    1. Activation of the Aryl Hydrocarbon Receptor by the Calcium/Calmodulin-Dependent Protein Kinase Kinase Inhibitor 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid (STO-609)
      Patricia Monteiro, David Gilot, Sophie Langouet and Olivier Fardel
      Drug Metabolism and Disposition December 2008, 36 (12) 2556-2563; DOI: https://doi.org/10.1124/dmd.108.023333

  3. Lavé, Thierry

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  4. Leet, John E.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  5. Leggas, Markos

    1. N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into Milk
      Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition December 2008, 36 (12) 2591-2596; DOI: https://doi.org/10.1124/dmd.108.021980

  6. Li, Wenying

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  7. Lipscomb, J. C.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

  8. Liu, Xiaohong

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  9. Lombardo, Louis J.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

M

  1. Ma, Shuguang

    1. Structural Characterization of Novel Adenine Dinucleotide Phosphate Conjugates of Imatinib in Incubations with Rat and Human Liver Microsomes
      Shuguang Ma, Raju Subramanian, Yang Xu, Michael Schrag and Magang Shou
      Drug Metabolism and Disposition December 2008, 36 (12) 2414-2418; DOI: https://doi.org/10.1124/dmd.108.023085

  2. Ma, Xiaochao

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  3. Maggs, James L.

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  4. Matthews, Jason

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  5. McNamara, Patrick J.

    1. N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into Milk
      Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition December 2008, 36 (12) 2591-2596; DOI: https://doi.org/10.1124/dmd.108.021980

  6. Mizugaki, Michinao

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  7. Monteiro, Patricia

    1. Activation of the Aryl Hydrocarbon Receptor by the Calcium/Calmodulin-Dependent Protein Kinase Kinase Inhibitor 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid (STO-609)
      Patricia Monteiro, David Gilot, Sophie Langouet and Olivier Fardel
      Drug Metabolism and Disposition December 2008, 36 (12) 2556-2563; DOI: https://doi.org/10.1124/dmd.108.023333

  8. Murray, Michael

    1. Interindividual Variation in Relative CYP1A2/3A4 Phenotype Influences Susceptibility of Clozapine Oxidation to Cytochrome P450-Specific Inhibition in Human Hepatic Microsomes
      Wei V. Zhang, Fabrizio D'Esposito, Robert J. Edwards, Iqbal Ramzan and Michael Murray
      Drug Metabolism and Disposition December 2008, 36 (12) 2547-2555; DOI: https://doi.org/10.1124/dmd.108.023671

N

  1. Naisbitt, Dean J.

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  2. Neale, Jason R.

    1. Systemic Functional Expression of N-Acetyltransferase Polymorphism in the F344 Nat2 Congenic Rat
      David W. Hein, Jean Bendaly, Jason R. Neale and Mark A. Doll
      Drug Metabolism and Disposition December 2008, 36 (12) 2452-2459; DOI: https://doi.org/10.1124/dmd.108.023960

  3. Nguyen-Dumont, T.

    1. Differential Allelic Expression in Leukoblast from Patients with Acute Myeloid Leukemia Suggests Genetic Regulation of CDA, DCK, NT5C2, NT5C3, and TP53
      L. P. Jordheim, T. Nguyen-Dumont, X. Thomas, C. Dumontet and S. V. Tavtigian
      Drug Metabolism and Disposition December 2008, 36 (12) 2419-2423; DOI: https://doi.org/10.1124/dmd.108.023184

  4. Nichols, Alice I.

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  5. Nick, Hanspeter

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  6. Nitta, Kayoko

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

  7. Novick, Rachel M.

    1. Purification and Characterization of Flavin-Containing Monooxygenase Isoform 3 from Rat Kidney Microsomes
      Rachel M. Novick and Adnan A. Elfarra
      Drug Metabolism and Disposition December 2008, 36 (12) 2468-2474; DOI: https://doi.org/10.1124/dmd.108.021436

O

  1. Obata, Kanako

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  2. Ohta, Shigeru

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

  3. Okey, Allan B.

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

P

  1. Park, B. Kevin

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  2. Patroneva, Albena

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  3. Paul, Jeffrey

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  4. Pearson, Josh T.

    1. The Combination of Chemical and Antibody Inhibitors for Superior P450 3A Inhibition in Reaction Phenotyping Studies
      Dan A. Rock, Robert S. Foti and Josh T. Pearson
      Drug Metabolism and Disposition December 2008, 36 (12) 2410-2413; DOI: https://doi.org/10.1124/dmd.108.023572

  5. Pedersen, Ron

    1. An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
      Albena Patroneva, Sandra M. Connolly, Penny Fatato, Ron Pedersen, Qin Jiang, Jeffrey Paul, Christine Guico-Pabia, Jennifer A. Isler, Michael E. Burczynski and Alice I. Nichols
      Drug Metabolism and Disposition December 2008, 36 (12) 2484-2491; DOI: https://doi.org/10.1124/dmd.108.021527

  6. Pohjanvirta, Raimo

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  7. Poirier, Agnès

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  8. Portmann, Renée

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

Q

  1. Qian, Ligang

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

R

  1. Ramzan, Iqbal

    1. Interindividual Variation in Relative CYP1A2/3A4 Phenotype Influences Susceptibility of Clozapine Oxidation to Cytochrome P450-Specific Inhibition in Human Hepatic Microsomes
      Wei V. Zhang, Fabrizio D'Esposito, Robert J. Edwards, Iqbal Ramzan and Michael Murray
      Drug Metabolism and Disposition December 2008, 36 (12) 2547-2555; DOI: https://doi.org/10.1124/dmd.108.023671

  2. Rao, Anuradha

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  3. Ristagno, Elizabeth H.

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564

  4. Roblin, Steven

    1. Aryl Hydrocarbon Receptor-Dependent Induction of Flavin-Containing Monooxygenase mRNAs in Mouse Liver
      Trine Celius, Steven Roblin, Patricia A. Harper, Jason Matthews, Paul C. Boutros, Raimo Pohjanvirta and Allan B. Okey
      Drug Metabolism and Disposition December 2008, 36 (12) 2499-2505; DOI: https://doi.org/10.1124/dmd.108.023457

  5. Rock, Dan A.

    1. The Combination of Chemical and Antibody Inhibitors for Superior P450 3A Inhibition in Reaction Phenotyping Studies
      Dan A. Rock, Robert S. Foti and Josh T. Pearson
      Drug Metabolism and Disposition December 2008, 36 (12) 2410-2413; DOI: https://doi.org/10.1124/dmd.108.023572

  6. Rodrigues, A. David

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  7. Rostami-Hodjegan, A.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

S

  1. Sakuyama, Kanako

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  2. Sanderson, Joseph P.

    1. Nonenzymatic Formation of a Novel Hydroxylated Sulfamethoxazole Derivative in Human Liver Microsomes: Implications for Bioanalysis of Sulfamethoxazole Metabolites
      Joseph P. Sanderson, Frank J. Hollis, James L. Maggs, Stephen E. Clarke, Dean J. Naisbitt and B. Kevin Park
      Drug Metabolism and Disposition December 2008, 36 (12) 2424-2428; DOI: https://doi.org/10.1124/dmd.108.021246

  3. Sasaki, Takamitsu

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  4. Schneider, Josef

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  5. Schrag, Michael

    1. Structural Characterization of Novel Adenine Dinucleotide Phosphate Conjugates of Imatinib in Incubations with Rat and Human Liver Microsomes
      Shuguang Ma, Raju Subramanian, Yang Xu, Michael Schrag and Magang Shou
      Drug Metabolism and Disposition December 2008, 36 (12) 2414-2418; DOI: https://doi.org/10.1124/dmd.108.023085

  6. Schweitzer, Alain

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  7. Scott, Emily E.

    1. Key Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A Enzymes
      Natasha M. DeVore, Brian D. Smith, Michael J. Urban and Emily E. Scott
      Drug Metabolism and Disposition December 2008, 36 (12) 2582-2590; DOI: https://doi.org/10.1124/dmd.108.023770

  8. Senner, Frank

    1. Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model
      Agnès Poirier, Thierry Lavé, Renée Portmann, Marie-Elise Brun, Frank Senner, Manfred Kansy, Hans-Peter Grimm and Christoph Funk
      Drug Metabolism and Disposition December 2008, 36 (12) 2434-2444; DOI: https://doi.org/10.1124/dmd.108.020750

  9. Shah, Yatrik M.

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  10. Shearn, Shawn P.

    1. Involvement of Intestinal Uptake Transporters in the Absorption of Azithromycin and Clarithromycin in the Rat
      Eric Garver, Erin D. Hugger, Shawn P. Shearn, Anuradha Rao, Paul A. Dawson, Charles B. Davis and Chao Han
      Drug Metabolism and Disposition December 2008, 36 (12) 2492-2498; DOI: https://doi.org/10.1124/dmd.108.022285

  11. Shou, Magang

    1. Structural Characterization of Novel Adenine Dinucleotide Phosphate Conjugates of Imatinib in Incubations with Rat and Human Liver Microsomes
      Shuguang Ma, Raju Subramanian, Yang Xu, Michael Schrag and Magang Shou
      Drug Metabolism and Disposition December 2008, 36 (12) 2414-2418; DOI: https://doi.org/10.1124/dmd.108.023085

  12. Shu, Yue-Zhong

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  13. Shyu, Wen-Chyi

    1. Lacteal Secretion, Fetal and Maternal Tissue Distribution of Dasatinib in Rats
      Kan He, Michael W. Lago, Ramaswamy A. Iyer, Wen-Chyi Shyu, William G. Humphreys and Lisa J. Christopher
      Drug Metabolism and Disposition December 2008, 36 (12) 2564-2570; DOI: https://doi.org/10.1124/dmd.108.022764

  14. Smith, Brian D.

    1. Key Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A Enzymes
      Natasha M. DeVore, Brian D. Smith, Michael J. Urban and Emily E. Scott
      Drug Metabolism and Disposition December 2008, 36 (12) 2582-2590; DOI: https://doi.org/10.1124/dmd.108.023770

  15. Snawder, J. E.

    1. Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
      Z. E. Barter, J. E. Chowdry, J. R. Harlow, J. E. Snawder, J. C. Lipscomb and A. Rostami-Hodjegan
      Drug Metabolism and Disposition December 2008, 36 (12) 2405-2409; DOI: https://doi.org/10.1124/dmd.108.021311

  16. States, J. Christopher

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564

  17. Subramanian, Raju

    1. Structural Characterization of Novel Adenine Dinucleotide Phosphate Conjugates of Imatinib in Incubations with Rat and Human Liver Microsomes
      Shuguang Ma, Raju Subramanian, Yang Xu, Michael Schrag and Magang Shou
      Drug Metabolism and Disposition December 2008, 36 (12) 2414-2418; DOI: https://doi.org/10.1124/dmd.108.023085

  18. Sugihara, Kazumi

    1. CYP2C9-Catalyzed Metabolism of S-Warfarin to 7-Hydroxywarfarin in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura and Shigeru Ohta
      Drug Metabolism and Disposition December 2008, 36 (12) 2429-2433; DOI: https://doi.org/10.1124/dmd.108.022830

T

  1. Tavtigian, S. V.

    1. Differential Allelic Expression in Leukoblast from Patients with Acute Myeloid Leukemia Suggests Genetic Regulation of CDA, DCK, NT5C2, NT5C3, and TP53
      L. P. Jordheim, T. Nguyen-Dumont, X. Thomas, C. Dumontet and S. V. Tavtigian
      Drug Metabolism and Disposition December 2008, 36 (12) 2419-2423; DOI: https://doi.org/10.1124/dmd.108.023184

  2. Tejwani, Ravindra W.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  3. Thomas, X.

    1. Differential Allelic Expression in Leukoblast from Patients with Acute Myeloid Leukemia Suggests Genetic Regulation of CDA, DCK, NT5C2, NT5C3, and TP53
      L. P. Jordheim, T. Nguyen-Dumont, X. Thomas, C. Dumontet and S. V. Tavtigian
      Drug Metabolism and Disposition December 2008, 36 (12) 2419-2423; DOI: https://doi.org/10.1124/dmd.108.023184

  4. Traeger, Sarah C.

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

U

  1. Ujiie, Shuta

    1. Functional Characterization of 17 CYP2D6 Allelic Variants (CYP2D6.2, 10, 14A–B, 18, 27, 36, 39, 47–51, 53–55, and 57)
      Kanako Sakuyama, Takamitsu Sasaki, Shuta Ujiie, Kanako Obata, Michinao Mizugaki, Masaaki Ishikawa and Masahiro Hiratsuka
      Drug Metabolism and Disposition December 2008, 36 (12) 2460-2467; DOI: https://doi.org/10.1124/dmd.108.023242

  2. Urban, Michael J.

    1. Key Residues Controlling Phenacetin Metabolism by Human Cytochrome P450 2A Enzymes
      Natasha M. DeVore, Brian D. Smith, Michael J. Urban and Emily E. Scott
      Drug Metabolism and Disposition December 2008, 36 (12) 2582-2590; DOI: https://doi.org/10.1124/dmd.108.023770

W

  1. Waldmeier, Felix

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

  2. Walraven, Jason M.

    1. Quantitative Tissue and Gene-Specific Differences and Developmental Changes in Nat1, Nat2, and Nat3 mRNA Expression in the Rat
      David F. Barker, Jason M. Walraven, Elizabeth H. Ristagno, Mark A. Doll, J. Christopher States and David W. Hein
      Drug Metabolism and Disposition December 2008, 36 (12) 2445-2451; DOI: https://doi.org/10.1124/dmd.108.023564

  3. Wang, Bei

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  4. Wang, Lipeng

    1. N-(4-[2-(1,2,3,4-Tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine Carboxamide (GF120918) As a Chemical ATP-Binding Cassette Transporter Family G Member 2 (Abcg2) Knockout Model to Study Nitrofurantoin Transfer into Milk
      Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E. Empey and Patrick J. McNamara
      Drug Metabolism and Disposition December 2008, 36 (12) 2591-2596; DOI: https://doi.org/10.1124/dmd.108.021980

  5. Wang, Ting

    1. A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
      Xiaochao Ma, Connie Cheung, Kristopher W. Krausz, Yatrik M. Shah, Ting Wang, Jeffrey R. Idle and Frank J. Gonzalez
      Drug Metabolism and Disposition December 2008, 36 (12) 2506-2512; DOI: https://doi.org/10.1124/dmd.108.022723

  6. Wei, Donna D.

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624

  7. Wen, Bo

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  8. Wiegand, Hansjörg

    1. Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and Its Iron Complex in Rats
      Gerard J. M. Bruin, Thomas Faller, Hansjörg Wiegand, Alain Schweitzer, Hanspeter Nick, Josef Schneider, K.-Olaf Boernsen and Felix Waldmeier
      Drug Metabolism and Disposition December 2008, 36 (12) 2523-2538; DOI: https://doi.org/10.1124/dmd.108.022962

X

  1. Xu, Yang

    1. Structural Characterization of Novel Adenine Dinucleotide Phosphate Conjugates of Imatinib in Incubations with Rat and Human Liver Microsomes
      Shuguang Ma, Raju Subramanian, Yang Xu, Michael Schrag and Magang Shou
      Drug Metabolism and Disposition December 2008, 36 (12) 2414-2418; DOI: https://doi.org/10.1124/dmd.108.023085

Z

  1. Zhang, Hongjian

    1. Confirmation That Cytochrome P450 2C8 (CYP2C8) Plays a Minor Role in (S)-(+)- and (R)-(-)-Ibuprofen Hydroxylation in Vitro
      Shu-Ying Chang, Wenying Li, Sarah C. Traeger, Bei Wang, Donghui Cui, Hongjian Zhang, Bo Wen and A. David Rodrigues
      Drug Metabolism and Disposition December 2008, 36 (12) 2513-2522; DOI: https://doi.org/10.1124/dmd.108.022970

  2. Zhang, Wei V.

    1. Interindividual Variation in Relative CYP1A2/3A4 Phenotype Influences Susceptibility of Clozapine Oxidation to Cytochrome P450-Specific Inhibition in Human Hepatic Microsomes
      Wei V. Zhang, Fabrizio D'Esposito, Robert J. Edwards, Iqbal Ramzan and Michael Murray
      Drug Metabolism and Disposition December 2008, 36 (12) 2547-2555; DOI: https://doi.org/10.1124/dmd.108.023671

  3. Zhang, Yueping

    1. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an Unusual N-Acetylglucosamine Conjugate in the Cynomolgus Monkey
      Benjamin M. Johnson, Amrita V. Kamath, John E. Leet, Xiaohong Liu, Rajeev S. Bhide, Ravindra W. Tejwani, Yueping Zhang, Ligang Qian, Donna D. Wei, Louis J. Lombardo and Yue-Zhong Shu
      Drug Metabolism and Disposition December 2008, 36 (12) 2475-2483; DOI: https://doi.org/10.1124/dmd.108.022624
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