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Research ArticleArticle

Biosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes Species

Antonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju Subramanian
Drug Metabolism and Disposition February 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323

Article Information

vol. 36 no. 2 234-240
DOI 
https://doi.org/10.1124/dmd.107.019323
PubMed 
18006646
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 17, 2007
  • Accepted November 12, 2007
  • Published online January 24, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Antonio Osorio-Lozada1,
  2. Sekhar Surapaneni2,
  3. Gary L. Skiles and
  4. Raju Subramanian
  1. Pharmacokinetics and Drug Metabolism, Amgen Inc., Thousand Oaks, California
  1. Address correspondence to:
    Dr. Raju Subramanian, One Amgen Center Dr. M/S 30E-2-B, Amgen Inc., Thousand Oaks, CA 91320. E-mail: rajus{at}amgen.com
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Research ArticleArticle

Biosynthesis of Drug Metabolites Using Microbes in Hollow Fiber Cartridge Reactors: Case Study of Diclofenac Metabolism by Actinoplanes Species

Antonio Osorio-Lozada, Sekhar Surapaneni, Gary L. Skiles and Raju Subramanian
Drug Metabolism and Disposition February 1, 2008, 36 (2) 234-240; DOI: https://doi.org/10.1124/dmd.107.019323
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