Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs

Donglu Zhang; Nirmala Raghavan; Shiang-Yuan Chen; Haiying Zhang; Mimi Quan; Lloyd Lecureux; Laura M. Patrone; Patrick Y. S. Lam; Samuel J. Bonacorsi; Robert M. Knabb; Gary L. Skiles; Kan He

doi:10.1124/dmd.107.018416

Research ArticleArticle

Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs

Donglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan He

Drug Metabolism and Disposition February 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416

Donglu Zhang

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Nirmala Raghavan

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Shiang-Yuan Chen

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Haiying Zhang

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Mimi Quan

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Lloyd Lecureux

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Laura M. Patrone

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Patrick Y. S. Lam

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Samuel J. Bonacorsi

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Robert M. Knabb

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Gary L. Skiles

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Kan He

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Drug Metabolism and Disposition

Vol. 36, Issue 2

1 Feb 2008

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Research ArticleArticle

Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs

Donglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan He

Drug Metabolism and Disposition February 1, 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416

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Research ArticleArticle

Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs

Donglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M. Patrone, Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles and Kan He

Drug Metabolism and Disposition February 1, 2008, 36 (2) 303-315; DOI: https://doi.org/10.1124/dmd.107.018416

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