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Research ArticleArticle

Azole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene Expression

Lucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr Pavek
Drug Metabolism and Disposition February 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
Lucie Svecova
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Radim Vrzal
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Ladislav Burysek
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Eva Anzenbacherova
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Lukas Cerveny
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Jiri Grim
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Frantisek Trejtnar
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Milan Pour
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Zdenek Dvorak
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Article Information

vol. 36 no. 2 339-348
DOI 
https://doi.org/10.1124/dmd.107.018341
PubMed 
17998298

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 16, 2007
  • Accepted November 7, 2007
  • Published online January 24, 2008.

Article Versions

  • Earlier version (November 12, 2007 - 08:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lucie Svecova,
  2. Radim Vrzal,
  3. Ladislav Burysek,
  4. Eva Anzenbacherova,
  5. Lukas Cerveny,
  6. Jiri Grim,
  7. Frantisek Trejtnar,
  8. Jiri Kunes,
  9. Milan Pour,
  10. Frantisek Staud,
  11. Pavel Anzenbacher,
  12. Zdenek Dvorak and
  13. Petr Pavek
  1. Departments of Pharmacology and Toxicology (L.S., F.T., F.S., P.P.) and Organic and Inorganic Chemistry (J.K., M.P.), Faculty of Pharmacy in Hradec Kralove, Charles University in Prague, Hradec Kralove, Czech Republic; Departments of Medical Chemistry and Biochemistry (R.V., E.A., Z.D.) and Pharmacology (P.A.), Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic; Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence in Hradec Kralove (L.C.), Department of Oncology and Radiotherapy, Faculty Hospital in Hradec Kralove, Czech Republic (J.G.); and Gen-Trend, s.r.o. České Budějovice, Czech Republic (L.B.)
  1. Address correspondence to:
    Dr. Petr Pavek, Department of Pharmacology and Toxicology, Charles University in Prague, Faculty of Pharmacy, Heyrovskeho 1203, Hradec Kralove, CZ-500 05, Czech Republic. E-mail: petr.pavek{at}faf.cuni.cz
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Drug Metabolism and Disposition: 36 (2)
Drug Metabolism and Disposition
Vol. 36, Issue 2
1 Feb 2008
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Research ArticleArticle

Azole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene Expression

Lucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr Pavek
Drug Metabolism and Disposition February 1, 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341

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Research ArticleArticle

Azole Antimycotics Differentially Affect Rifampicin-Induced Pregnane X Receptor-Mediated CYP3A4 Gene Expression

Lucie Svecova, Radim Vrzal, Ladislav Burysek, Eva Anzenbacherova, Lukas Cerveny, Jiri Grim, Frantisek Trejtnar, Jiri Kunes, Milan Pour, Frantisek Staud, Pavel Anzenbacher, Zdenek Dvorak and Petr Pavek
Drug Metabolism and Disposition February 1, 2008, 36 (2) 339-348; DOI: https://doi.org/10.1124/dmd.107.018341
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