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Research ArticleArticle

Influence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard Prodrugs

Nuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. Tingle
Drug Metabolism and Disposition February 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
Nuala A. Helsby
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Michael A. Goldthorpe
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Magdalene H. Y. Tang
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Graham J. Atwell
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Eileen M. Smith
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William R. Wilson
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Malcolm D. Tingle
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Article Information

vol. 36 no. 2 353-360
DOI 
https://doi.org/10.1124/dmd.107.018739
PubMed 
17998296

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 5, 2007
  • Accepted November 9, 2007
  • Published online January 24, 2008.

Article Versions

  • Earlier version (November 12, 2007 - 08:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nuala A. Helsby,
  2. Michael A. Goldthorpe,
  3. Magdalene H. Y. Tang,
  4. Graham J. Atwell,
  5. Eileen M. Smith,
  6. William R. Wilson and
  7. Malcolm D. Tingle
  1. Department of Molecular Medicine and Pathology (N.A.H.), Department of Pharmacology (M.A.G., M.H.Y.T., M.D.T.), and Auckland Cancer Society Research Centre (N.A.H., G.J.A, E.M.S., W.R.W.), Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
  1. Address correspondence to:
    Dr. Nuala A. Helsby, Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand. E-mail: n.helsby{at}auckland.ac.nz
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Drug Metabolism and Disposition: 36 (2)
Drug Metabolism and Disposition
Vol. 36, Issue 2
1 Feb 2008
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Research ArticleArticle

Influence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard Prodrugs

Nuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. Tingle
Drug Metabolism and Disposition February 1, 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739

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Research ArticleArticle

Influence of Mustard Group Structure on Pathways of in Vitro Metabolism of Anticancer N-(2-Hydroxyethyl)-3,5-dinitrobenzamide 2-Mustard Prodrugs

Nuala A. Helsby, Michael A. Goldthorpe, Magdalene H. Y. Tang, Graham J. Atwell, Eileen M. Smith, William R. Wilson and Malcolm D. Tingle
Drug Metabolism and Disposition February 1, 2008, 36 (2) 353-360; DOI: https://doi.org/10.1124/dmd.107.018739
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