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Research ArticleArticle

Product Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT Substrates

Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
Drug Metabolism and Disposition February 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705
Ryoichi Fujiwara
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Miki Nakajima
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Hiroyuki Yamanaka
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Miki Katoh
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Tsuyoshi Yokoi
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Article Information

vol. 36 no. 2 361-367
DOI 
https://doi.org/10.1124/dmd.107.018705
PubMed 
17998297

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 2, 2007
  • Accepted November 9, 2007
  • Published online January 24, 2008.

Article Versions

  • Earlier version (November 12, 2007 - 08:20).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ryoichi Fujiwara,
  2. Miki Nakajima,
  3. Hiroyuki Yamanaka,
  4. Miki Katoh and
  5. Tsuyoshi Yokoi
  1. Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
  1. Address correspondence to:
    Dr. Tsuyoshi Yokoi, Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. E-mail: tyokoi{at}kenroku.kanazawa-u.ac.jp
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Drug Metabolism and Disposition: 36 (2)
Drug Metabolism and Disposition
Vol. 36, Issue 2
1 Feb 2008
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Research ArticleArticle

Product Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT Substrates

Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
Drug Metabolism and Disposition February 1, 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705

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Research ArticleArticle

Product Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT Substrates

Ryoichi Fujiwara, Miki Nakajima, Hiroyuki Yamanaka, Miki Katoh and Tsuyoshi Yokoi
Drug Metabolism and Disposition February 1, 2008, 36 (2) 361-367; DOI: https://doi.org/10.1124/dmd.107.018705
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