Product Inhibition of UDP-Glucuronosyltransferase (UGT) Enzymes by UDP Obfuscates the Inhibitory Effects of UGT Substrates

Address correspondence to:
Dr. Tsuyoshi Yokoi, Drug Metabolism and Toxicology, Division of Pharmaceutical Sciences, Graduate School of Medical Science, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. E-mail: tyokoi{at}kenroku.kanazawa-u.ac.jp

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: November 2007 to October 2020

	Abstract	Full	Pdf
Nov 2007	54	0	127
Dec 2007	17	0	110
Jan 2008	44	10	83
Feb 2008	50	51	71
Mar 2008	30	32	51
Apr 2008	36	35	47
May 2008	27	27	34
Jun 2008	39	26	31
Jul 2008	23	41	34
Aug 2008	20	15	17
Sep 2008	42	24	39
Oct 2008	39	27	33
Nov 2008	29	18	31
Dec 2008	20	13	16
Jan 2009	23	22	22
Feb 2009	10	40	35
Mar 2009	16	50	42
Apr 2009	10	55	41
May 2009	9	47	49
Jun 2009	8	51	30
Jul 2009	10	21	23
Aug 2009	7	32	28
Sep 2009	7	37	21
Oct 2009	26	43	31
Nov 2009	15	28	23
Dec 2009	27	16	20
Jan 2010	39	37	33
Feb 2010	12	34	36
Mar 2010	28	49	33
Apr 2010	24	56	19
May 2010	33	38	24
Jun 2010	35	50	27
Jul 2010	25	53	33
Aug 2010	17	31	17
Sep 2010	13	37	19
Oct 2010	31	40	26
Nov 2010	30	28	20
Dec 2010	27	29	28
Jan 2011	24	33	30
Feb 2011	23	31	23
Mar 2011	37	21	21
Apr 2011	21	36	31
May 2011	24	33	28
Jun 2011	22	30	34
Jul 2011	23	29	21
Aug 2011	26	31	26
Sep 2011	33	30	20
Oct 2011	26	43	28
Nov 2011	24	61	34
Dec 2011	10	41	17
Jan 2012	8	49	32
Feb 2012	26	42	29
Mar 2012	28	41	19
Apr 2012	24	33	22
May 2012	33	47	22
Jun 2012	20	67	40
Jul 2012	20	72	32
Aug 2012	18	44	34
Sep 2012	23	39	25
Oct 2012	21	37	33
Nov 2012	16	41	31
Dec 2012	19	42	34
Jan 2013	40	65	36
Feb 2013	21	63	37
Mar 2013	25	57	28
Apr 2013	37	66	37
May 2013	26	49	37
Jun 2013	12	38	24
Jul 2013	8	21	15
Aug 2013	20	33	16
Sep 2013	46	45	19
Oct 2013	8	39	14
Nov 2013	12	53	25
Dec 2013	7	33	15
Jan 2014	8	60	26
Feb 2014	16	52	14
Mar 2014	14	70	40
Apr 2014	11	50	20
May 2014	24	50	125
Jun 2014	27	47	114
Jul 2014	15	56	33
Aug 2014	6	46	20
Sep 2014	19	52	20
Oct 2014	23	35	27
Nov 2014	15	37	21
Dec 2014	11	28	4
Jan 2015	19	44	15
Feb 2015	4	32	12
Mar 2015	14	37	10
Apr 2015	13	38	8
May 2015	12	43	28
Jun 2015	13	64	26
Jul 2015	18	69	29
Aug 2015	13	38	18
Sep 2015	5	55	20
Oct 2015	3	40	15
Nov 2015	10	40	17
Dec 2015	9	43	14
Jan 2016	11	42	16
Feb 2016	31	66	26
Mar 2016	11	47	23
Apr 2016	33	53	13
May 2016	6	46	20
Jun 2016	15	52	32
Jul 2016	1	34	20
Aug 2016	7	59	23
Sep 2016	6	53	30
Oct 2016	1	50	12
Nov 2016	3	35	16
Dec 2016	2	28	22
Jan 2017	2	56	24
Feb 2017	1	33	4
Mar 2017	1	50	12
Apr 2017	3	36	14
May 2017	0	44	20
Jun 2017	0	32	18
Jul 2017	1	37	23
Aug 2017	2	38	28
Sep 2017	0	35	26
Oct 2017	1	38	7
Nov 2017	1	85	18
Dec 2017	0	36	12
Jan 2018	1	42	15
Feb 2018	4	88	12
Mar 2018	0	38	4
Apr 2018	2	38	5
May 2018	3	44	29
Jun 2018	2	48	12
Jul 2018	1	33	21
Aug 2018	3	39	9
Sep 2018	0	30	22
Oct 2018	1	34	16
Nov 2018	0	41	9
Dec 2018	28	10	10
Jan 2019	28	6	5
Feb 2019	32	12	7
Mar 2019	46	7	8
Apr 2019	17	6	10
May 2019	40	9	5
Jun 2019	15	5	6
Jul 2019	26	3	12
Aug 2019	36	6	9
Sep 2019	31	6	6
Oct 2019	40	8	6
Nov 2019	32	11	10
Dec 2019	55	12	7
Jan 2020	23	3	9
Feb 2020	16	9	3
Mar 2020	39	12	10
Apr 2020	25	1	2
May 2020	22	7	4
Jun 2020	17	7	11
Jul 2020	30	2	1
Aug 2020	19	4	9
Sep 2020	17	2	8
Oct 2020	16	15	1