Table of Contents

Articles

• You have access

  CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile

  Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia

  Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501
• You have access

  A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor

  Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim

  Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547
• You have access

  Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols

  Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu

  Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299
• You have access

  The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis

  Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya

  Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469
• You have access

  CYP2C19 Inhibition: The Impact of Substrate Probe Selection on in Vitro Inhibition Profiles

  Robert S. Foti and Jan L. Wahlstrom

  Drug Metabolism and Disposition March 2008, 36 (3) 523-528; DOI: https://doi.org/10.1124/dmd.107.019265
• You have access

  CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528

  Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji

  Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853
• You have access

  Drug Lipophilicity and Microsomal Protein Concentration as Determinants in the Prediction of the Fraction Unbound in Microsomal Incubations

  Michael Gertz, Peter J. Kilford, J. Brian Houston and Aleksandra Galetin

  Drug Metabolism and Disposition March 2008, 36 (3) 535-542; DOI: https://doi.org/10.1124/dmd.107.018713
• You have access

  Regulation of Aryl Hydrocarbon Receptor Expression and Function by Glucocorticoids in Mouse Hepatoma Cells

  Kirsten A. Bielefeld, Chunja Lee and David S. Riddick

  Drug Metabolism and Disposition March 2008, 36 (3) 543-551; DOI: https://doi.org/10.1124/dmd.107.019703
• You have access

  Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites

  Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole

  Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661
• You have access

  Metabolism of the Trisubstituted Purine Cyclin-Dependent Kinase Inhibitor Seliciclib (R-Roscovitine) in Vitro and in Vivo

  Steven J. McClue and Iain Stuart

  Drug Metabolism and Disposition March 2008, 36 (3) 561-570; DOI: https://doi.org/10.1124/dmd.107.019232
• You have access

  Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes

  Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis

  Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954
• You have access

  Physical Incorporation of NADPH-Cytochrome P450 Reductase and Cytochrome P450 into Phospholipid Vesicles Using Glycocholate and Bio-Beads

  James R. Reed, Lauren M. Brignac-Huber and Wayne L. Backes

  Drug Metabolism and Disposition March 2008, 36 (3) 582-588; DOI: https://doi.org/10.1124/dmd.107.018473
• You have access

  Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats

  Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai

  Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004
• You have access

  Down-Regulation of Hepatic Cytochrome P450 Enzymes in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis

  Yasuhiro Masubuchi, Kanako Enoki and Toshiharu Horie

  Drug Metabolism and Disposition March 2008, 36 (3) 597-603; DOI: https://doi.org/10.1124/dmd.107.018754
• You have access

  Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro

  Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis

  Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820
• You have access

  High-Affinity Binding of [³H]Cimetidine to a Heme-Containing Protein in Rat Brain

  Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough

  Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889