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Index by author

March 01, 2008; Volume 36,Issue 3

B

  1. Backes, Wayne L.

    1. Physical Incorporation of NADPH-Cytochrome P450 Reductase and Cytochrome P450 into Phospholipid Vesicles Using Glycocholate and Bio-Beads
      James R. Reed, Lauren M. Brignac-Huber and Wayne L. Backes
      Drug Metabolism and Disposition March 2008, 36 (3) 582-588; DOI: https://doi.org/10.1124/dmd.107.018473

  2. Bielefeld, Kirsten A.

    1. Regulation of Aryl Hydrocarbon Receptor Expression and Function by Glucocorticoids in Mouse Hepatoma Cells
      Kirsten A. Bielefeld, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition March 2008, 36 (3) 543-551; DOI: https://doi.org/10.1124/dmd.107.019703

  3. Blomme, Eric A. G.

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  4. Bratton, Stacie M.

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  5. Brignac-Huber, Lauren M.

    1. Physical Incorporation of NADPH-Cytochrome P450 Reductase and Cytochrome P450 into Phospholipid Vesicles Using Glycocholate and Bio-Beads
      James R. Reed, Lauren M. Brignac-Huber and Wayne L. Backes
      Drug Metabolism and Disposition March 2008, 36 (3) 582-588; DOI: https://doi.org/10.1124/dmd.107.018473

  6. Bui, Tot

    1. In Vitro-to-in Vivo Prediction of P-glycoprotein-Based Drug Interactions at the Human and Rodent Blood-Brain Barrier
      Peng Hsiao, Tot Bui, Rodney J. Y. Ho and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2008, 36 (3) 481-484; DOI: https://doi.org/10.1124/dmd.107.018176

C

  1. Catania, Viviana A.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

  2. Chang, Wen-Ni

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  3. Chen, Bing-Hung

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  4. Chi, Chin-Wen

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

  5. Chung, Hye Jin

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

  6. Cole, Susan P. C.

    1. Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites
      Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole
      Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661

  7. Correia, Maria Almira

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

D

  1. Deeley, Roger G.

    1. Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites
      Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole
      Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661

  2. de Graaf, Inge A. M.

    1. Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro
      Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
      Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820

E

  1. Enoki, Kanako

    1. Down-Regulation of Hepatic Cytochrome P450 Enzymes in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis
      Yasuhiro Masubuchi, Kanako Enoki and Toshiharu Horie
      Drug Metabolism and Disposition March 2008, 36 (3) 597-603; DOI: https://doi.org/10.1124/dmd.107.018754

F

  1. Finel, Moshe

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  2. Foti, Robert S.

    1. CYP2C19 Inhibition: The Impact of Substrate Probe Selection on in Vitro Inhibition Profiles
      Robert S. Foti and Jan L. Wahlstrom
      Drug Metabolism and Disposition March 2008, 36 (3) 523-528; DOI: https://doi.org/10.1124/dmd.107.019265

  3. Fu, Tzu-Fun

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

G

  1. Galetin, Aleksandra

    1. Drug Lipophilicity and Microsomal Protein Concentration as Determinants in the Prediction of the Fraction Unbound in Microsomal Incubations
      Michael Gertz, Peter J. Kilford, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2008, 36 (3) 535-542; DOI: https://doi.org/10.1124/dmd.107.018713

  2. Gertz, Michael

    1. Drug Lipophilicity and Microsomal Protein Concentration as Determinants in the Prediction of the Fraction Unbound in Microsomal Incubations
      Michael Gertz, Peter J. Kilford, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2008, 36 (3) 535-542; DOI: https://doi.org/10.1124/dmd.107.018713

  3. Ghanem, Carolina I.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

  4. Goldman, Adrian

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  5. Groothuis, Geny M. M.

    1. Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro
      Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
      Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820

H

  1. Healan-Greenberg, Christine

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  2. Ho, Rodney J. Y.

    1. In Vitro-to-in Vivo Prediction of P-glycoprotein-Based Drug Interactions at the Human and Rodent Blood-Brain Barrier
      Peng Hsiao, Tot Bui, Rodney J. Y. Ho and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2008, 36 (3) 481-484; DOI: https://doi.org/10.1124/dmd.107.018176

  3. Honda, Tomoyo

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  4. Horie, Toshiharu

    1. Down-Regulation of Hepatic Cytochrome P450 Enzymes in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis
      Yasuhiro Masubuchi, Kanako Enoki and Toshiharu Horie
      Drug Metabolism and Disposition March 2008, 36 (3) 597-603; DOI: https://doi.org/10.1124/dmd.107.018754

  5. Hough, Lindsay B.

    1. High-Affinity Binding of [3H]Cimetidine to a Heme-Containing Protein in Rat Brain
      Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough
      Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889

  6. Houston, J. Brian

    1. Drug Lipophilicity and Microsomal Protein Concentration as Determinants in the Prediction of the Fraction Unbound in Microsomal Incubations
      Michael Gertz, Peter J. Kilford, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2008, 36 (3) 535-542; DOI: https://doi.org/10.1124/dmd.107.018713

  7. Hsiao, Peng

    1. In Vitro-to-in Vivo Prediction of P-glycoprotein-Based Drug Interactions at the Human and Rodent Blood-Brain Barrier
      Peng Hsiao, Tot Bui, Rodney J. Y. Ho and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2008, 36 (3) 481-484; DOI: https://doi.org/10.1124/dmd.107.018176

  8. Hung, Shih-Chieh

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

I

  1. Ikeda, Toshihiko

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  2. Ishizuka-Ozeki, Tomoko

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  3. Iwabuchi, Haruo

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

K

  1. Kamber, Matthias

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

  2. Kang, Min Jung

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

  3. Kang, Ping

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

  4. Kao, Tseng-Ting

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  5. Kempf, Dale J.

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  6. Kilford, Peter J.

    1. Drug Lipophilicity and Microsomal Protein Concentration as Determinants in the Prediction of the Fraction Unbound in Microsomal Incubations
      Michael Gertz, Peter J. Kilford, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition March 2008, 36 (3) 535-542; DOI: https://doi.org/10.1124/dmd.107.018713

  7. Kim, Dong-Hyun

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

  8. Kim, Richard B.

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  9. Kostiainen, Risto

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

  10. Kotsuma, Masakatsu

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  11. Kuuranne, Tiia

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

L

  1. Lee, Chang-Seok

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

  2. Lee, Chunja

    1. Regulation of Aryl Hydrocarbon Receptor Expression and Function by Glucocorticoids in Mouse Hepatoma Cells
      Kirsten A. Bielefeld, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition March 2008, 36 (3) 543-551; DOI: https://doi.org/10.1124/dmd.107.019703

  3. Lee, Jaeick

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

  4. Leeder, J. Steven

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

  5. Leinonen, Antti

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

  6. Liao, Mingxiang

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

  7. Lin, Chi-Hung

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

  8. Lin, Chia-Ying

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  9. Lin, Lie-Chwen

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

  10. Luquita, Marcelo G.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

M

  1. Masubuchi, Yasuhiro

    1. Down-Regulation of Hepatic Cytochrome P450 Enzymes in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis
      Yasuhiro Masubuchi, Kanako Enoki and Toshiharu Horie
      Drug Metabolism and Disposition March 2008, 36 (3) 597-603; DOI: https://doi.org/10.1124/dmd.107.018754

  2. McClue, Steven J.

    1. Metabolism of the Trisubstituted Purine Cyclin-Dependent Kinase Inhibitor Seliciclib (R-Roscovitine) in Vitro and in Vivo
      Steven J. McClue and Iain Stuart
      Drug Metabolism and Disposition March 2008, 36 (3) 561-570; DOI: https://doi.org/10.1124/dmd.107.019232

  3. Miley, Michael J.

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  4. Miller, Grover P.

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  5. Monks, Terrence J.

    1. Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites
      Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole
      Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661

  6. Mottino, Aldo D.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

  7. Murai, Takahiro

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

N

  1. Nalwalk, Julia W.

    1. High-Affinity Binding of [3H]Cimetidine to a Heme-Containing Protein in Rat Brain
      Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough
      Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889

P

  1. Patana, Anne-Sisko

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  2. Pearce, Robin E.

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

  3. Phillips, James G.

    1. High-Affinity Binding of [3H]Cimetidine to a Heme-Containing Protein in Rat Brain
      Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough
      Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889

R

  1. Radominska-Pandya, Anna

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  2. Redinbo, Matt R.

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

  3. Reed, James R.

    1. Physical Incorporation of NADPH-Cytochrome P450 Reductase and Cytochrome P450 into Phospholipid Vesicles Using Glycocholate and Bio-Beads
      James R. Reed, Lauren M. Brignac-Huber and Wayne L. Backes
      Drug Metabolism and Disposition March 2008, 36 (3) 582-588; DOI: https://doi.org/10.1124/dmd.107.018473

  4. Riddick, David S.

    1. Regulation of Aryl Hydrocarbon Receptor Expression and Function by Glucocorticoids in Mouse Hepatoma Cells
      Kirsten A. Bielefeld, Chunja Lee and David S. Riddick
      Drug Metabolism and Disposition March 2008, 36 (3) 543-551; DOI: https://doi.org/10.1124/dmd.107.019703

  5. Ruiz, María L.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

S

  1. Saji, Hideo

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  2. Schänzer, Wilhelm

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

  3. Shi, Guey-Yueh

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  4. Slot, Andrew J.

    1. Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites
      Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole
      Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661

  5. Stadel, Rebecca

    1. High-Affinity Binding of [3H]Cimetidine to a Heme-Containing Protein in Rat Brain
      Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough
      Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889

  6. Stuart, Iain

    1. Metabolism of the Trisubstituted Purine Cyclin-Dependent Kinase Inhibitor Seliciclib (R-Roscovitine) in Vitro and in Vivo
      Steven J. McClue and Iain Stuart
      Drug Metabolism and Disposition March 2008, 36 (3) 561-570; DOI: https://doi.org/10.1124/dmd.107.019232

T

  1. Thevis, Mario

    1. Aryl-Propionamide-Derived Selective Androgen Receptor Modulators: Liquid Chromatography-Tandem Mass Spectrometry Characterization of the in Vitro Synthesized Metabolites for Doping Control Purposes
      Tiia Kuuranne, Antti Leinonen, Wilhelm Schänzer, Matthias Kamber, Risto Kostiainen and Mario Thevis
      Drug Metabolism and Disposition March 2008, 36 (3) 571-581; DOI: https://doi.org/10.1124/dmd.107.017954

  2. Tirona, Rommel G.

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  3. Tokui, Taro

    1. CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528
      Masakatsu Kotsuma, Taro Tokui, Tomoko Ishizuka-Ozeki, Tomoyo Honda, Haruo Iwabuchi, Takahiro Murai, Toshihiko Ikeda and Hideo Saji
      Drug Metabolism and Disposition March 2008, 36 (3) 529-534; DOI: https://doi.org/10.1124/dmd.107.018853

  4. Tsai, Jen-Ning

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  5. Tsai, Tung-Hu

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

U

  1. Unadkat, Jashvant D.

    1. In Vitro-to-in Vivo Prediction of P-glycoprotein-Based Drug Interactions at the Human and Rodent Blood-Brain Barrier
      Peng Hsiao, Tot Bui, Rodney J. Y. Ho and Jashvant D. Unadkat
      Drug Metabolism and Disposition March 2008, 36 (3) 481-484; DOI: https://doi.org/10.1124/dmd.107.018176

  2. Ungell, Anna-Lena B.

    1. Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro
      Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
      Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820

V

  1. van de Kerkhof, Esther G.

    1. Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro
      Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
      Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820

  2. Villanueva, Silvina S. M.

    1. Hepatic Synthesis and Urinary Elimination of Acetaminophen Glucuronide Are Exacerbated in Bile Duct-Ligated Rats
      Silvina S. M. Villanueva, María L. Ruiz, Carolina I. Ghanem, Marcelo G. Luquita, Viviana A. Catania and Aldo D. Mottino
      Drug Metabolism and Disposition March 2008, 36 (3) 475-480; DOI: https://doi.org/10.1124/dmd.107.018127

W

  1. Wahlstrom, Jan L.

    1. CYP2C19 Inhibition: The Impact of Substrate Probe Selection on in Vitro Inhibition Profiles
      Robert S. Foti and Jan L. Wahlstrom
      Drug Metabolism and Disposition March 2008, 36 (3) 523-528; DOI: https://doi.org/10.1124/dmd.107.019265

  2. Wang, Kuan-Chieh

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  3. Waring, Jeffrey F.

    1. A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor
      Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

  4. Wester, Michael R.

    1. CYP3A4-Mediated Carbamazepine (CBZ) Metabolism: Formation of a Covalent CBZ-CYP3A4 Adduct and Alteration of the Enzyme Kinetic Profile
      Ping Kang, Mingxiang Liao, Michael R. Wester, J. Steven Leeder, Robin E. Pearce and Maria Almira Correia
      Drug Metabolism and Disposition March 2008, 36 (3) 490-499; DOI: https://doi.org/10.1124/dmd.107.016501

  5. Wise, Dana D.

    1. Modulation of Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) Transport Activities by Endogenous and Exogenous Glutathione-Conjugated Catechol Metabolites
      Andrew J. Slot, Dana D. Wise, Roger G. Deeley, Terrence J. Monks and Susan P. C. Cole
      Drug Metabolism and Disposition March 2008, 36 (3) 552-560; DOI: https://doi.org/10.1124/dmd.107.019661

  6. Wu, Hua-Lin

    1. Characterization and Comparative Studies of Zebrafish and Human Recombinant Dihydrofolate Reductases—Inhibition by Folic Acid and Polyphenols
      Tseng-Ting Kao, Kuan-Chieh Wang, Wen-Ni Chang, Chia-Ying Lin, Bing-Hung Chen, Hua-Lin Wu, Guey-Yueh Shi, Jen-Ning Tsai and Tzu-Fun Fu
      Drug Metabolism and Disposition March 2008, 36 (3) 508-516; DOI: https://doi.org/10.1124/dmd.107.019299

  7. Wu, Jhy-Wen

    1. Hepatobiliary Excretion of Silibinin in Normal and Liver Cirrhotic Rats
      Jhy-Wen Wu, Lie-Chwen Lin, Shih-Chieh Hung, Chi-Hung Lin, Chin-Wen Chi and Tung-Hu Tsai
      Drug Metabolism and Disposition March 2008, 36 (3) 589-596; DOI: https://doi.org/10.1124/dmd.107.017004

X

  1. Xiong, Yan

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469

Y

  1. Yang, Jun

    1. High-Affinity Binding of [3H]Cimetidine to a Heme-Containing Protein in Rat Brain
      Rebecca Stadel, Jun Yang, Julia W. Nalwalk, James G. Phillips and Lindsay B. Hough
      Drug Metabolism and Disposition March 2008, 36 (3) 614-621; DOI: https://doi.org/10.1124/dmd.107.017889

  2. Yoo, Hye Hyun

    1. Enzymatic C-Demethylation of 1-[2-(5-tert-Butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1,1-dimethyl-ethylamino)-ethanone (LC15-0133) in Rat Liver Microsomes
      Hye Hyun Yoo, Hye Jin Chung, Jaeick Lee, Chang-Seok Lee, Min Jung Kang and Dong-Hyun Kim
      Drug Metabolism and Disposition March 2008, 36 (3) 485-489; DOI: https://doi.org/10.1124/dmd.107.019133

Z

  1. Zielinska, Agnieszka K.

    1. The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis
      Yan Xiong, Anne-Sisko Patana, Michael J. Miley, Agnieszka K. Zielinska, Stacie M. Bratton, Grover P. Miller, Adrian Goldman, Moshe Finel, Matt R. Redinbo and Anna Radominska-Pandya
      Drug Metabolism and Disposition March 2008, 36 (3) 517-522; DOI: https://doi.org/10.1124/dmd.107.016469
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