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Research ArticleArticle

A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor

Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
Drug Metabolism and Disposition March 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547

Article Information

vol. 36 no. 3 500-507
DOI 
https://doi.org/10.1124/dmd.107.019547
PubMed 
18096673
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 31, 2007
  • Accepted December 19, 2007
  • Published online February 22, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Christine Healan-Greenberg,
  2. Jeffrey F. Waring,
  3. Dale J. Kempf,
  4. Eric A. G. Blomme,
  5. Rommel G. Tirona and
  6. Richard B. Kim
  1. Abbott Laboratories, Global Pharmaceutical Research and Development, Abbott Park, Illinois (C.H.-G., J.F.W., D.J.K., E.A.G.B.); and Division of Clinical Pharmacology, Department of Medicine and Department of Physiology & Pharmacology, the University of Western Ontario, Schulich School of Medicine & Dentistry, London, Ontario, Canada (R.G.T., R.B.K.)
  1. Address correspondence to:
    Dr. Jeffrey F. Waring, Molecular and Cellular Toxicology, Abbott Laboratories Bldg. AP9A R463, 100 Abbott Park Road, Abbott Park, IL 60064-6104. E-mail: jeff.waring{at}abbott.com
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Research ArticleArticle

A Human Immunodeficiency Virus Protease Inhibitor Is a Novel Functional Inhibitor of Human Pregnane X Receptor

Christine Healan-Greenberg, Jeffrey F. Waring, Dale J. Kempf, Eric A. G. Blomme, Rommel G. Tirona and Richard B. Kim
Drug Metabolism and Disposition March 1, 2008, 36 (3) 500-507; DOI: https://doi.org/10.1124/dmd.107.019547
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