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Drug Metabolism & Disposition

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Table of Contents

April 01, 2008; Volume 36,Issue 4

Articles

  • You have access
    Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
    James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
    Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596
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    Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
    Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
    Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620
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    Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
    Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
    Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572
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    Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
    Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
    Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869
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    Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
    Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
    Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760
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    Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
    Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
    Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
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    In Vitro Hepatic and Skin Metabolism of Capsaicin
    Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
    Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240
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    Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
    Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
    Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639
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    Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
    Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
    Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764
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    Contribution of UDP-Glucuronosyltransferase 1A1 and 1A8 to Morphine-6-Glucuronidation and Its Kinetic Properties
    Shuji Ohno, Kiyoshi Kawana and Shizuo Nakajin
    Drug Metabolism and Disposition April 2008, 36 (4) 688-694; DOI: https://doi.org/10.1124/dmd.107.019281
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    The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
    Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
    Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374
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    Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
    Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
    Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358
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    Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
    Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
    Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315
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    Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib
    Wenying Li, Jonathan L. Josephs, Gary L. Skiles and W. Griffith Humphreys
    Drug Metabolism and Disposition April 2008, 36 (4) 721-730; DOI: https://doi.org/10.1124/dmd.107.019570
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    Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
    Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
    Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463
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    Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
    Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
    Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448
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    Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
    Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
    Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824
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    Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals
    Ronald E. Savage, Andrew N. Tyler, Xiu-Sheng Miao and Thomas C. K. Chan
    Drug Metabolism and Disposition April 2008, 36 (4) 753-758; DOI: https://doi.org/10.1124/dmd.107.018655
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    Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
    Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
    Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067
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    Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
    Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
    Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275
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    Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
    Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
    Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366
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    Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
    Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
    Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903
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Drug Metabolism and Disposition: 36 (4)
Drug Metabolism and Disposition
Vol. 36, Issue 4
1 Apr 2008
  • Table of Contents
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