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Index by author

April 01, 2008; Volume 36,Issue 4

A

  1. Adams, Bruce

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

  2. Ashwell, Mark A.

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

B

  1. Babbar, Sunita

    1. In Vitro Hepatic and Skin Metabolism of Capsaicin
      Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
      Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240

  2. Badagnani, Ilaria

    1. Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
      Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
      Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764

  3. Bashir, Mohammad

    1. In Vitro Hepatic and Skin Metabolism of Capsaicin
      Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
      Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240

  4. Benet, Leslie Z.

    1. Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
      Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
      Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764

  5. Bhadresa, Sanjeev

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

  6. Blanchard, Nadège

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  7. Bley, Keith

    1. In Vitro Hepatic and Skin Metabolism of Capsaicin
      Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
      Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240

  8. Bonet, Alexandre

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  9. Boom, Sandra

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  10. Burstein, Aaron H.

    1. Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
      Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
      Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760

C

  1. Castellino, Stephen

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  2. Chan, Thomas C. K.

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572
    2. Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals
      Ronald E. Savage, Andrew N. Tyler, Xiu-Sheng Miao and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 753-758; DOI: https://doi.org/10.1124/dmd.107.018655

  3. Chanda, Sanjay

    1. In Vitro Hepatic and Skin Metabolism of Capsaicin
      Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
      Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240

  4. Cleton, Adriaan

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  5. Coon, David James

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

D

  1. De Boeck, Gert

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  2. Dolgos, Hugues

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

E

  1. Ebner, Thomas

    1. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  2. Eerdekens, Marielle

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

F

  1. Fife, Kimberly L.

    1. Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
      Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
      Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764

  2. Folkerts, Gert

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  3. Fusch, Christoph

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

G

  1. Grillo, Mark P.

    1. Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
      Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
      Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764

  2. Grootenboers, Marco

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  3. Guetens, Gunther

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  4. Gunduz, Mithat

    1. Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
      Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
      Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760

H

  1. Halkic, Nermin

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  2. Hamada, Akinobu

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  3. Han, Jing-Fen

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  4. Harmon, Kelly A.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  5. Harsch, Andreas

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

  6. He, Xiao-Yang

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  7. He, Xiaoying

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

  8. Hendrickx, Jan

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  9. Hendriks, Jeroen M. H.

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  10. Herrington, Jason S.

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  11. Heyd, Bruno

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  12. Hong, Jun-Yan

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  13. Humphreys, Joan E.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  14. Humphreys, W. Griffith

    1. Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib
      Wenying Li, Jonathan L. Josephs, Gary L. Skiles and W. Griffith Humphreys
      Drug Metabolism and Disposition April 2008, 36 (4) 721-730; DOI: https://doi.org/10.1124/dmd.107.019570

  15. Hunt, C. Anthony

    1. Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
      Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
      Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067

I

  1. Igarashi, Takashi

    1. Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
      Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
    2. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  2. Inui, Ken-ichi

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  3. Ishiguro, Naoki

    1. Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
      Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
    2. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

J

  1. James, Margaret O.

    1. Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
      James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
      Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596

  2. Jeliazkova-Mecheva, Valentina V.

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

  3. John-Williams, Lisa St.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  4. Josephs, Jonathan L.

    1. Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib
      Wenying Li, Jonathan L. Josephs, Gary L. Skiles and W. Griffith Humphreys
      Drug Metabolism and Disposition April 2008, 36 (4) 721-730; DOI: https://doi.org/10.1124/dmd.107.019570

K

  1. Kawana, Kiyoshi

    1. Contribution of UDP-Glucuronosyltransferase 1A1 and 1A8 to Morphine-6-Glucuronidation and Its Kinetic Properties
      Shuji Ohno, Kiyoshi Kawana and Shizuo Nakajin
      Drug Metabolism and Disposition April 2008, 36 (4) 688-694; DOI: https://doi.org/10.1124/dmd.107.019281

  2. Kishimoto, Wataru

    1. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  3. Kizer, Darin

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

  4. Koch, Kevin M.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  5. Koganti, Aruna

    1. In Vitro Hepatic and Skin Metabolism of Capsaicin
      Sanjay Chanda, Mohammad Bashir, Sunita Babbar, Aruna Koganti and Keith Bley
      Drug Metabolism and Disposition April 2008, 36 (4) 670-675; DOI: https://doi.org/10.1124/dmd.107.019240

  6. Kroemer, Heyo K.

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

  7. Kwei, Gloria

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

L

  1. Lamba, Jatinder

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  2. Lawrence, Matthew S.

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

  3. Lehmler, Hans-Joachim

    1. Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
      James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
      Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596

  4. Li, Chunze

    1. Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats
      Chunze Li, Mark P. Grillo, Ilaria Badagnani, Kimberly L. Fife and Leslie Z. Benet
      Drug Metabolism and Disposition April 2008, 36 (4) 682-687; DOI: https://doi.org/10.1124/dmd.107.017764

  5. Li, Wenjun

    1. Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
      James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
      Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596

  6. Li, Wenying

    1. Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib
      Wenying Li, Jonathan L. Josephs, Gary L. Skiles and W. Griffith Humphreys
      Drug Metabolism and Disposition April 2008, 36 (4) 721-730; DOI: https://doi.org/10.1124/dmd.107.019570

  7. Linnemann, Knud

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

M

  1. Maeda, Kazuya

    1. Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
      Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
    2. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  2. Magiera, Daniel

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

  3. Mannens, Geert

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  4. Matsushima, Soichiro

    1. Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
      Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
    2. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  5. Matsuzaki, Takanobu

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  6. May, Karen

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

  7. Miao, Xiu-Sheng

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572
    2. Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals
      Ronald E. Savage, Andrew N. Tyler, Xiu-Sheng Miao and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 753-758; DOI: https://doi.org/10.1124/dmd.107.018655

  8. Minarikova, Veronika

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

  9. Morisaki, Takafumi

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  10. Mueller, Stefan O.

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

N

  1. Naessens, Ineke

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  2. Nakajin, Shizuo

    1. Contribution of UDP-Glucuronosyltransferase 1A1 and 1A8 to Morphine-6-Glucuronidation and Its Kinetic Properties
      Shuji Ohno, Kiyoshi Kawana and Shizuo Nakajin
      Drug Metabolism and Disposition April 2008, 36 (4) 688-694; DOI: https://doi.org/10.1124/dmd.107.019281

  3. Nisbett, Ernell

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

  4. Nonoguchi, Hiroshi

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

O

  1. O'Mara, Michael J.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  2. Ohno, Shuji

    1. Contribution of UDP-Glucuronosyltransferase 1A1 and 1A8 to Morphine-6-Glucuronidation and Its Kinetic Properties
      Shuji Ohno, Kiyoshi Kawana and Shizuo Nakajin
      Drug Metabolism and Disposition April 2008, 36 (4) 688-694; DOI: https://doi.org/10.1124/dmd.107.019281

  3. Olson, Katie L.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

P

  1. Park, Sunwoo

    1. Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
      Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
      Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067

  2. Pasterkamp, Gerard

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  3. Polli, Joseph W.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  4. Poonkuzhali, Balasubramanian

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

R

  1. Remmerie, Bart

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  2. Richert, Lysiane

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  3. Robertson, Larry W.

    1. Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
      James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
      Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596

  4. Ropella, Glen E. P.

    1. Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
      Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
      Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067

  5. Roth, Willy

    1. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

S

  1. Sacco, James C.

    1. Glucuronidation of Polychlorinated Biphenylols and UDP-Glucuronic Acid Concentrations in Channel Catfish Liver and Intestine
      James C. Sacco, Hans-Joachim Lehmler, Larry W. Robertson, Wenjun Li and Margaret O. James
      Drug Metabolism and Disposition April 2008, 36 (4) 623-630; DOI: https://doi.org/10.1124/dmd.107.019596

  2. Saito, Asami

    1. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  3. Saito, Hideyuki

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  4. Sato, Daisuke

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  5. Savage, Ronald E.

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572
    2. Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals
      Ronald E. Savage, Andrew N. Tyler, Xiu-Sheng Miao and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 753-758; DOI: https://doi.org/10.1124/dmd.107.018655

  6. Schinkel, Alfred H.

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  7. Schramel, Franz

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  8. Schuetz, Erin

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  9. Serabjit-Singh, Cosette J.

    1. The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions
      Joseph W. Polli, Joan E. Humphreys, Kelly A. Harmon, Stephen Castellino, Michael J. O'Mara, Katie L. Olson, Lisa St. John-Williams, Kevin M. Koch and Cosette J. Serabjit-Singh
      Drug Metabolism and Disposition April 2008, 36 (4) 695-701; DOI: https://doi.org/10.1124/dmd.107.018374

  10. Shaffer, Christopher L.

    1. Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
      Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
      Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760

  11. Sheihk-Bahaei, Shahab

    1. Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
      Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
      Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067

  12. Siegmund, Werner

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448

  13. Skiles, Gary L.

    1. Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib
      Wenying Li, Jonathan L. Josephs, Gary L. Skiles and W. Griffith Humphreys
      Drug Metabolism and Disposition April 2008, 36 (4) 721-730; DOI: https://doi.org/10.1124/dmd.107.019570

  14. Song, Pengfei

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

  15. Sparreboom, Alex

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  16. Sterkens, Patrick

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  17. Strom, Stephen

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  18. Sugimoto, Wakako

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  19. Sugiyama, Yuichi

    1. Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans
      Soichiro Matsushima, Kazuya Maeda, Naoki Ishiguro, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 663-669; DOI: https://doi.org/10.1124/dmd.107.017814
    2. Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide
      Naoki Ishiguro, Kazuya Maeda, Asami Saito, Wataru Kishimoto, Soichiro Matsushima, Thomas Ebner, Willy Roth, Takashi Igarashi and Yuichi Sugiyama
      Drug Metabolism and Disposition April 2008, 36 (4) 796-805; DOI: https://doi.org/10.1124/dmd.107.018903

  20. Supko, Jeffrey G.

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

T

  1. Talluri, Krishna

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  2. Terada, Tomohiro

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  3. Thummel, Kenneth

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  4. Tomita, Kimio

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

  5. Trimble, Laird

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

  6. Tuschl, Gregor

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  7. Tyler, Andrew N.

    1. Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals
      Ronald E. Savage, Andrew N. Tyler, Xiu-Sheng Miao and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 753-758; DOI: https://doi.org/10.1124/dmd.107.018655

V

  1. van Boven, Wim-Jan

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  2. van de Steeg, Evita

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  3. van de Wetering, Koen

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  4. van Osselaer, Nancy

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  5. van Putte, Bart P.

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  6. van Schil, Paul E. Y.

    1. Pharmacokinetics of Gemcitabine when Delivered by Selective Pulmonary Artery Perfusion for the Treatment of Lung Cancer
      Bart P. van Putte, Marco Grootenboers, Wim-Jan van Boven, Jeroen M. H. Hendriks, Paul E. Y. van Schil, Gunther Guetens, Gert De Boeck, Gerard Pasterkamp, Franz Schramel and Gert Folkerts
      Drug Metabolism and Disposition April 2008, 36 (4) 676-681; DOI: https://doi.org/10.1124/dmd.106.014639

  7. Vaz, Alfin D.

    1. Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
      Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
      Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760

  8. Venkatakrishnan, Karthik

    1. Metabolism and Disposition of a γ-Aminobutyric Acid Type A Receptor Partial Agonist in Humans
      Christopher L. Shaffer, Mithat Gunduz, Alfin D. Vaz, Karthik Venkatakrishnan and Aaron H. Burstein
      Drug Metabolism and Disposition April 2008, 36 (4) 655-662; DOI: https://doi.org/10.1124/dmd.107.019760

  9. Vens, Conchita

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  10. Vermeir, Marc

    1. Absorption, Metabolism, and Excretion of Paliperidone, a New Monoaminergic Antagonist, in Humans
      Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer and Adriaan Cleton
      Drug Metabolism and Disposition April 2008, 36 (4) 769-779; DOI: https://doi.org/10.1124/dmd.107.018275

  11. Viollon-Abadie, Catherine

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  12. Volckova, Erika

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

W

  1. Wagenaar, Els

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  2. Ward, Keith W.

    1. Exploration of the African Green Monkey as a Preclinical Pharmacokinetic Model: Intravenous Pharmacokinetic Parameters
      Keith W. Ward, David James Coon, Daniel Magiera, Sanjeev Bhadresa, Ernell Nisbett and Matthew S. Lawrence
      Drug Metabolism and Disposition April 2008, 36 (4) 715-720; DOI: https://doi.org/10.1124/dmd.107.019315

  3. Watkins, Paul

    1. Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms
      Balasubramanian Poonkuzhali, Jatinder Lamba, Stephen Strom, Alex Sparreboom, Kenneth Thummel, Paul Watkins and Erin Schuetz
      Drug Metabolism and Disposition April 2008, 36 (4) 780-795; DOI: https://doi.org/10.1124/dmd.107.018366

  4. White, Lori A.

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  5. Wimmer, Elmar

    1. Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro
      Lysiane Richert, Gregor Tuschl, Catherine Viollon-Abadie, Nadège Blanchard, Alexandre Bonet, Bruno Heyd, Nermin Halkic, Elmar Wimmer, Hugues Dolgos and Stefan O. Mueller
      Drug Metabolism and Disposition April 2008, 36 (4) 702-714; DOI: https://doi.org/10.1124/dmd.107.018358

  6. Wu, Hui

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

X

  1. Xu, Lin

    1. Identification of Novel Metabolites of Colchicine in Rat Bile Facilitated by Enhanced Online Radiometric Detection
      Lin Xu, Bruce Adams, Valentina V. Jeliazkova-Mecheva, Laird Trimble, Gloria Kwei and Andreas Harsch
      Drug Metabolism and Disposition April 2008, 36 (4) 731-739; DOI: https://doi.org/10.1124/dmd.107.019463

Y

  1. Yan, Li

    1. Predictions of Hepatic Disposition Properties Using a Mechanistically Realistic, Physiologically Based Model
      Li Yan, Shahab Sheihk-Bahaei, Sunwoo Park, Glen E. P. Ropella and C. Anthony Hunt
      Drug Metabolism and Disposition April 2008, 36 (4) 759-768; DOI: https://doi.org/10.1124/dmd.107.019067

  2. Yang, Rui-Yang

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

  3. Yokoo, Koji

    1. Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury
      Takanobu Matsuzaki, Takafumi Morisaki, Wakako Sugimoto, Koji Yokoo, Daisuke Sato, Hiroshi Nonoguchi, Kimio Tomita, Tomohiro Terada, Ken-ichi Inui, Akinobu Hamada and Hideyuki Saito
      Drug Metabolism and Disposition April 2008, 36 (4) 649-654; DOI: https://doi.org/10.1124/dmd.107.019869

Z

  1. Zhang, Jun-Feng

    1. Metabolism of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by Human CYP1B1 Genetic Variants
      Jing-Fen Han, Xiao-Yang He, Jason S. Herrington, Lori A. White, Jun-Feng Zhang and Jun-Yan Hong
      Drug Metabolism and Disposition April 2008, 36 (4) 745-752; DOI: https://doi.org/10.1124/dmd.107.016824

  2. Zhong, Caiyun

    1. Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood
      Xiu-Sheng Miao, Pengfei Song, Ronald E. Savage, Caiyun Zhong, Rui-Yang Yang, Darin Kizer, Hui Wu, Erika Volckova, Mark A. Ashwell, Jeffrey G. Supko, Xiaoying He and Thomas C. K. Chan
      Drug Metabolism and Disposition April 2008, 36 (4) 641-648; DOI: https://doi.org/10.1124/dmd.107.018572

  3. Zimmermann, Christian

    1. Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
      Christian Zimmermann, Koen van de Wetering, Evita van de Steeg, Els Wagenaar, Conchita Vens and Alfred H. Schinkel
      Drug Metabolism and Disposition April 2008, 36 (4) 631-640; DOI: https://doi.org/10.1124/dmd.107.019620

  4. Zygmunt, Marek

    1. Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta
      Karen May, Veronika Minarikova, Knud Linnemann, Marek Zygmunt, Heyo K. Kroemer, Christoph Fusch and Werner Siegmund
      Drug Metabolism and Disposition April 2008, 36 (4) 740-744; DOI: https://doi.org/10.1124/dmd.107.019448
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