Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Table of Contents

May 01, 2008; Volume 36,Issue 5

Short Communications

  • You have access
    Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
    Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
    Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624
  • You have access
    Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
    Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
    Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

Articles

  • You have access
    Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
    Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
    Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002
  • You have access
    Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
    Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
    Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406
  • You have access
    Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
    Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
    Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168
  • You have access
    Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine
    Bo Wen, Li Ma, A. David Rodrigues and Mingshe Zhu
    Drug Metabolism and Disposition May 2008, 36 (5) 841-850; DOI: https://doi.org/10.1124/dmd.107.019471
  • You have access
    Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
    Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
    Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539
  • You have access
    Differential Roles of P-Glycoprotein, Multidrug Resistance-Associated Protein 2, and CYP3A on Saquinavir Oral Absorption in Sprague-Dawley Rats
    Helen H. Usansky, Peidi Hu and Patrick J. Sinko
    Drug Metabolism and Disposition May 2008, 36 (5) 863-869; DOI: https://doi.org/10.1124/dmd.107.017483
  • You have access
    The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
    Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
    Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885
  • You have access
    Synergism of Glucocorticoid Hormone with Growth Hormone for Female-Specific Mouse Cyp3a44 Gene Expression
    Tsutomu Sakuma, Wattanaporn Bhadhprasit, Tadahiro Hashita and Nobuo Nemoto
    Drug Metabolism and Disposition May 2008, 36 (5) 878-884; DOI: https://doi.org/10.1124/dmd.107.019935
  • You have access
    Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
    Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
    Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042
  • You have access
    In Vitro Metabolism of 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] Acetic Acid (Licofelone, ML3000), an Inhibitor of Cyclooxygenase-1 and -2 and 5-Lipoxygenase
    Wolfgang Albrecht, Anke Unger, Andreas K. Nussler and Stefan Laufer
    Drug Metabolism and Disposition May 2008, 36 (5) 894-903; DOI: https://doi.org/10.1124/dmd.108.020347
  • You have access
    Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
    Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
    Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895
  • You have access
    Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
    Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
    Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273
  • You have access
    Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
    Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
    Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040
  • You have access
    Unique Transcription Start Sites and Distinct Promoter Regions Differentiate the Pregnane X Receptor (PXR) Isoforms PXR 1 and PXR 2
    Leslie M. Tompkins, Tim L. Sit and Andrew D. Wallace
    Drug Metabolism and Disposition May 2008, 36 (5) 923-929; DOI: https://doi.org/10.1124/dmd.107.018317
  • You have access
    Slipping Past UGT1A1 and Multidrug Resistance-Associated Protein 2 in the Liver: Effects of Steric Compression and Hydrogen Bonding on the Hepatobiliary Elimination of Synthetic Bilirubins
    Antony F. McDonagh, Stefan E. Boiadjiev and David A. Lightner
    Drug Metabolism and Disposition May 2008, 36 (5) 930-936; DOI: https://doi.org/10.1124/dmd.107.019778
  • You have access
    Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
    Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
    Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174
  • You have access
    Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
    Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
    Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598
  • You have access
    Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
    Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
    Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349
  • You have access
    CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
    Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
    Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960
  • You have access
    Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
    Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
    Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034
Back to top
PreviousNext

In this issue

Drug Metabolism and Disposition: 36 (5)
Drug Metabolism and Disposition
Vol. 36, Issue 5
1 May 2008
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • Short Communications
  • Articles
  • Most Cited
  • Most Read
Loading
  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics