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Index by author

May 01, 2008; Volume 36,Issue 5

A

  1. Albrecht, Wolfgang

    1. In Vitro Metabolism of 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] Acetic Acid (Licofelone, ML3000), an Inhibitor of Cyclooxygenase-1 and -2 and 5-Lipoxygenase
      Wolfgang Albrecht, Anke Unger, Andreas K. Nussler and Stefan Laufer
      Drug Metabolism and Disposition May 2008, 36 (5) 894-903; DOI: https://doi.org/10.1124/dmd.108.020347

  2. Arabeyre-Fabre, Catherine

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  3. Asagarasu, Akira

    1. Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
      Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
      Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168

B

  1. Bains, Onkar S.

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  2. Baldwin, R. Michael

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  3. Belinsky, Martin G.

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

  4. Bhadhprasit, Wattanaporn

    1. Synergism of Glucocorticoid Hormone with Growth Hormone for Female-Specific Mouse Cyp3a44 Gene Expression
      Tsutomu Sakuma, Wattanaporn Bhadhprasit, Tadahiro Hashita and Nobuo Nemoto
      Drug Metabolism and Disposition May 2008, 36 (5) 878-884; DOI: https://doi.org/10.1124/dmd.107.019935

  5. Boiadjiev, Stefan E.

    1. Slipping Past UGT1A1 and Multidrug Resistance-Associated Protein 2 in the Liver: Effects of Steric Compression and Hydrogen Bonding on the Hepatobiliary Elimination of Synthetic Bilirubins
      Antony F. McDonagh, Stefan E. Boiadjiev and David A. Lightner
      Drug Metabolism and Disposition May 2008, 36 (5) 930-936; DOI: https://doi.org/10.1124/dmd.107.019778

  6. Bourrie, Martine

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  7. Brouwer, Kim L. R.

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

  8. Buckley, Arthur R.

    1. Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
      Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
      Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598

  9. Buckley, Donna J.

    1. Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
      Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
      Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598

C

  1. Cantiello, Michela

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  2. Capolongo, Francesca

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  3. Carlberg, Anne

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  4. Carletti, Monica

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  5. Chen, Gang

    1. Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
      Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
      Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406

  6. Chow, Edwin C. Y.

    1. Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
      Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
      Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174

D

  1. Dacasto, Mauro

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  2. Dellinger, Ryan W.

    1. Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
      Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
      Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406

  3. Desai, Pankaj B.

    1. Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
      Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
      Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598

  4. Dopp, Elke

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

E

  1. Edenro, Anne

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  2. Elliot, David J.

    1. The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
      Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885

  3. Emmert, Gary L.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

F

  1. Fabre, Gérard

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  2. Fedeli, Olivier

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  3. Fransson-Steen, Ronny

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

G

  1. Giantin, Mery

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  2. Grigliatti, Thomas A.

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  3. Guillou, François

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  4. Gusson, Federica

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

H

  1. Hao, Liping

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  2. Hartmann, Louise M.

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  3. Hashita, Tadahiro

    1. Synergism of Glucocorticoid Hormone with Growth Hormone for Female-Specific Mouse Cyp3a44 Gene Expression
      Tsutomu Sakuma, Wattanaporn Bhadhprasit, Tadahiro Hashita and Nobuo Nemoto
      Drug Metabolism and Disposition May 2008, 36 (5) 878-884; DOI: https://doi.org/10.1124/dmd.107.019935

  4. Hiratsuka, Masahiro

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  5. Hirner, Alfred V.

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  6. Hu, Peidi

    1. Differential Roles of P-Glycoprotein, Multidrug Resistance-Associated Protein 2, and CYP3A on Saquinavir Oral Absorption in Sprague-Dawley Rats
      Helen H. Usansky, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition May 2008, 36 (5) 863-869; DOI: https://doi.org/10.1124/dmd.107.017483

  7. Hugla, Sébastien

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

I

  1. Ingelman-Sundberg, Magnus

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

J

  1. Jung, Young S.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

K

  1. Kataoka, Makoto

    1. Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
      Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
      Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040

  2. Katier, Cindy

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  3. Kawabata, Takeshi

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  4. Kim, Young C.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

  5. Kitamura, Yoshiaki

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  6. Klieber, Sylvie

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  7. Kluger, Ronald H.

    1. Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
      Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
      Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174

  8. Knights, Kathleen M.

    1. The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
      Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885

  9. Koto, Hisao

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  10. Kruh, Gary D.

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

  11. Kusuhara, Hiroyuki

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

L

  1. Laufer, Stefan

    1. In Vitro Metabolism of 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] Acetic Acid (Licofelone, ML3000), an Inhibitor of Cyclooxygenase-1 and -2 and 5-Lipoxygenase
      Wolfgang Albrecht, Anke Unger, Andreas K. Nussler and Stefan Laufer
      Drug Metabolism and Disposition May 2008, 36 (5) 894-903; DOI: https://doi.org/10.1124/dmd.108.020347

  2. Lax, Sigurd F.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  3. Lazarus, Philip

    1. Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
      Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
      Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406

  4. Lee, Dae Y.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

  5. Lee, Joo H.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

  6. Lee, Myung G.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

  7. Lightner, David A.

    1. Slipping Past UGT1A1 and Multidrug Resistance-Associated Protein 2 in the Liver: Effects of Steric Compression and Hydrogen Bonding on the Hepatobiliary Elimination of Synthetic Bilirubins
      Antony F. McDonagh, Stefan E. Boiadjiev and David A. Lightner
      Drug Metabolism and Disposition May 2008, 36 (5) 930-936; DOI: https://doi.org/10.1124/dmd.107.019778

  8. Lindqvist, Annelie

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  9. Liu, Lichuan

    1. Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
      Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
      Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174

  10. Löfgren, Susanne

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  11. Lopparelli, Rosa Maria

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

M

  1. Ma, Li

    1. Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine
      Bo Wen, Li Ma, A. David Rodrigues and Mingshe Zhu
      Drug Metabolism and Disposition May 2008, 36 (5) 841-850; DOI: https://doi.org/10.1124/dmd.107.019471

  2. Mackenzie, Peter I.

    1. The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
      Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885

  3. Martin, Pascal

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  4. Masaoka, Yoshie

    1. Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
      Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
      Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040

  5. Masumoto, Hiroshi

    1. Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
      Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
      Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002

  6. Matsui, Teruaki

    1. Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
      Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
      Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168

  7. Matsuura, Shinobu

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  8. Maurel, Patrick

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  9. McDonagh, Antony F.

    1. Slipping Past UGT1A1 and Multidrug Resistance-Associated Protein 2 in the Liver: Effects of Steric Compression and Hydrogen Bonding on the Hepatobiliary Elimination of Synthetic Bilirubins
      Antony F. McDonagh, Stefan E. Boiadjiev and David A. Lightner
      Drug Metabolism and Disposition May 2008, 36 (5) 930-936; DOI: https://doi.org/10.1124/dmd.107.019778

  10. Meunier, Viviane

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  11. Minato, Kouichi

    1. Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
      Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
      Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168

  12. Miners, John O.

    1. The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
      Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885

  13. Mitsuru, Ayako

    1. Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
      Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
      Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002

N

  1. Nallani, Srikanth C.

    1. Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
      Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
      Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598

  2. Nebbia, Carlo

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  3. Nemoto, Nobuo

    1. Synergism of Glucocorticoid Hormone with Growth Hormone for Female-Specific Mouse Cyp3a44 Gene Expression
      Tsutomu Sakuma, Wattanaporn Bhadhprasit, Tadahiro Hashita and Nobuo Nemoto
      Drug Metabolism and Disposition May 2008, 36 (5) 878-884; DOI: https://doi.org/10.1124/dmd.107.019935

  4. Ngo, Robert

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  5. Nussler, Andreas

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  6. Nussler, Andreas K.

    1. In Vitro Metabolism of 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] Acetic Acid (Licofelone, ML3000), an Inhibitor of Cyclooxygenase-1 and -2 and 5-Lipoxygenase
      Wolfgang Albrecht, Anke Unger, Andreas K. Nussler and Stefan Laufer
      Drug Metabolism and Disposition May 2008, 36 (5) 894-903; DOI: https://doi.org/10.1124/dmd.108.020347

O

  1. Okazaki, Osamu

    1. Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
      Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
      Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002

P

  1. Pang, K. Sandy

    1. Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
      Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
      Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174

  2. Pegolo, Sara

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  3. Pfeifer, Tom A.

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  4. Pineau, Thierry

    1. Effect of Breed upon Cytochromes P450 and Phase II Enzyme Expression in Cattle Liver
      Mery Giantin, Monica Carletti, Francesca Capolongo, Sara Pegolo, Rosa Maria Lopparelli, Federica Gusson, Carlo Nebbia, Michela Cantiello, Pascal Martin, Thierry Pineau and Mauro Dacasto
      Drug Metabolism and Disposition May 2008, 36 (5) 885-893; DOI: https://doi.org/10.1124/dmd.107.019042

  5. Pollok, Ilona

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

R

  1. Rabieh, Sasan

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  2. Rahman, Mostafizur

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  3. Reid, Ronald E.

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  4. Rettenmeier, Albert W.

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  5. Riggs, K. Wayne

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  6. Rival, Martine

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  7. Rodrigues, A. David

    1. Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine
      Bo Wen, Li Ma, A. David Rodrigues and Mingshe Zhu
      Drug Metabolism and Disposition May 2008, 36 (5) 841-850; DOI: https://doi.org/10.1124/dmd.107.019471

  8. Rowland, Andrew

    1. The “Albumin Effect” and in Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450 2C9
      Andrew Rowland, David J. Elliot, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition May 2008, 36 (5) 870-877; DOI: https://doi.org/10.1124/dmd.107.019885

  9. Russo, Jose

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

S

  1. Sadoun, Freddy

    1. Contribution of the N-Glucuronidation Pathway to the Overall in Vitro Metabolic Clearance of Midazolam in Humans
      Sylvie Klieber, Sébastien Hugla, Robert Ngo, Catherine Arabeyre-Fabre, Viviane Meunier, Freddy Sadoun, Olivier Fedeli, Martine Rival, Martine Bourrie, François Guillou, Patrick Maurel and Gérard Fabre
      Drug Metabolism and Disposition May 2008, 36 (5) 851-862; DOI: https://doi.org/10.1124/dmd.107.019539

  2. Sakuma, Shinji

    1. Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
      Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
      Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040

  3. Sakuma, Tsutomu

    1. Synergism of Glucocorticoid Hormone with Growth Hormone for Female-Specific Mouse Cyp3a44 Gene Expression
      Tsutomu Sakuma, Wattanaporn Bhadhprasit, Tadahiro Hashita and Nobuo Nemoto
      Drug Metabolism and Disposition May 2008, 36 (5) 878-884; DOI: https://doi.org/10.1124/dmd.107.019935

  4. Sane, Rucha S.

    1. Role of Human Pregnane X Receptor in Tamoxifen- and 4-Hydroxytamoxifen-Mediated CYP3A4 Induction in Primary Human Hepatocytes and LS174T Cells
      Rucha S. Sane, Donna J. Buckley, Arthur R. Buckley, Srikanth C. Nallani and Pankaj B. Desai
      Drug Metabolism and Disposition May 2008, 36 (5) 946-954; DOI: https://doi.org/10.1124/dmd.107.018598

  5. Santen, Richard J.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  6. Sato, Michitaka

    1. Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
      Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
      Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168

  7. Schülke, Meint

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  8. Ship, Noam

    1. Role of Haptoglobin on the Uptake of Native and β-Chain [Trimesoyl-(Lys82)β-(Lys82)β] Cross-Linked Human Hemoglobins in Isolated Perfused Rat Livers
      Edwin C. Y. Chow, Lichuan Liu, Noam Ship, Ronald H. Kluger and K. Sandy Pang
      Drug Metabolism and Disposition May 2008, 36 (5) 937-945; DOI: https://doi.org/10.1124/dmd.107.019174

  9. Shirasaka, Yoshiyuki

    1. Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
      Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
      Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040

  10. Sim, Sarah C.

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  11. Sinko, Patrick J.

    1. Differential Roles of P-Glycoprotein, Multidrug Resistance-Associated Protein 2, and CYP3A on Saquinavir Oral Absorption in Sprague-Dawley Rats
      Helen H. Usansky, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition May 2008, 36 (5) 863-869; DOI: https://doi.org/10.1124/dmd.107.017483

  12. Sit, Tim L.

    1. Unique Transcription Start Sites and Distinct Promoter Regions Differentiate the Pregnane X Receptor (PXR) Isoforms PXR 1 and PXR 2
      Leslie M. Tompkins, Tim L. Sit and Andrew D. Wallace
      Drug Metabolism and Disposition May 2008, 36 (5) 923-929; DOI: https://doi.org/10.1124/dmd.107.018317

  13. Snait, Michael

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  14. Spratt, Thomas E.

    1. Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
      Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
      Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406

  15. Stevens, Gaylene L.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  16. Stueckradt, Inga

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

  17. Sudo, Kenichi

    1. Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
      Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
      Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002

  18. Sugiyama, Yuichi

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  19. Sun, Dongxiao

    1. Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
      Gang Chen, Ryan W. Dellinger, Dongxiao Sun, Thomas E. Spratt and Philip Lazarus
      Drug Metabolism and Disposition May 2008, 36 (5) 824-830; DOI: https://doi.org/10.1124/dmd.107.019406

  20. Sutter, Carrie H.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  21. Sutter, Thomas R.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  22. Suzuki, Ryota

    1. Biotransformation of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel 5-Hydroxytryptamine (5-HT)1A Agonist/5-HT3 Antagonist, in Human Hepatic Cytochrome P450 Enzymes
      Kouichi Minato, Ryota Suzuki, Akira Asagarasu, Teruaki Matsui and Michitaka Sato
      Drug Metabolism and Disposition May 2008, 36 (5) 831-840; DOI: https://doi.org/10.1124/dmd.107.018168

  23. Swift, Brandon

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

T

  1. Takahashi, Ryan H.

    1. Two Allelic Variants of Aldo-Keto Reductase 1A1 Exhibit Reduced in Vitro Metabolism of Daunorubicin
      Onkar S. Bains, Ryan H. Takahashi, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition May 2008, 36 (5) 904-910; DOI: https://doi.org/10.1124/dmd.107.018895

  2. Takakusa, Hideo

    1. Markers of Electrophilic Stress Caused by Chemically Reactive Metabolites in Human Hepatocytes
      Hideo Takakusa, Hiroshi Masumoto, Ayako Mitsuru, Osamu Okazaki and Kenichi Sudo
      Drug Metabolism and Disposition May 2008, 36 (5) 816-823; DOI: https://doi.org/10.1124/dmd.107.018002

  3. Terelius, Ylva

    1. Generation of Mice Transgenic for Human CYP2C18 and CYP2C19: Characterization of the Sexually Dimorphic Gene and Enzyme Expression
      Susanne Löfgren, R. Michael Baldwin, Masahiro Hiratsuka, Annelie Lindqvist, Anne Carlberg, Sarah C. Sim, Meint Schülke, Michael Snait, Anne Edenro, Ronny Fransson-Steen, Ylva Terelius and Magnus Ingelman-Sundberg
      Drug Metabolism and Disposition May 2008, 36 (5) 955-962; DOI: https://doi.org/10.1124/dmd.107.019349

  4. Tian, Xianbin

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

  5. Tompkins, Leslie M.

    1. Unique Transcription Start Sites and Distinct Promoter Regions Differentiate the Pregnane X Receptor (PXR) Isoforms PXR 1 and PXR 2
      Leslie M. Tompkins, Tim L. Sit and Andrew D. Wallace
      Drug Metabolism and Disposition May 2008, 36 (5) 923-929; DOI: https://doi.org/10.1124/dmd.107.018317

  6. Tran, Quynh T.

    1. CYP1B1 Is Not a Major Determinant of the Disposition of Aromatase Inhibitors in Epithelial Cells of Invasive Ductal Carcinoma
      Mostafizur Rahman, Sigurd F. Lax, Carrie H. Sutter, Quynh T. Tran, Gaylene L. Stevens, Gary L. Emmert, Jose Russo, Richard J. Santen and Thomas R. Sutter
      Drug Metabolism and Disposition May 2008, 36 (5) 963-970; DOI: https://doi.org/10.1124/dmd.107.018960

  7. Tsuchiya, Hiroshi

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

  8. Tsujimoto, Hajime

    1. Modest Effect of Impaired P-glycoprotein on the Plasma Concentrations of Fexofenadine, Quinidine, and Loperamide following Oral Administration in Collies
      Yoshiaki Kitamura, Hisao Koto, Shinobu Matsuura, Takeshi Kawabata, Hiroshi Tsuchiya, Hiroyuki Kusuhara, Hajime Tsujimoto and Yuichi Sugiyama
      Drug Metabolism and Disposition May 2008, 36 (5) 807-810; DOI: https://doi.org/10.1124/dmd.107.017624

U

  1. Unger, Anke

    1. In Vitro Metabolism of 2-[6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] Acetic Acid (Licofelone, ML3000), an Inhibitor of Cyclooxygenase-1 and -2 and 5-Lipoxygenase
      Wolfgang Albrecht, Anke Unger, Andreas K. Nussler and Stefan Laufer
      Drug Metabolism and Disposition May 2008, 36 (5) 894-903; DOI: https://doi.org/10.1124/dmd.108.020347

  2. Usansky, Helen H.

    1. Differential Roles of P-Glycoprotein, Multidrug Resistance-Associated Protein 2, and CYP3A on Saquinavir Oral Absorption in Sprague-Dawley Rats
      Helen H. Usansky, Peidi Hu and Patrick J. Sinko
      Drug Metabolism and Disposition May 2008, 36 (5) 863-869; DOI: https://doi.org/10.1124/dmd.107.017483

V

  1. von Recklinghausen, Ursula

    1. Subcellular Distribution of Inorganic and Methylated Arsenic Compounds in Human Urothelial Cells and Human Hepatocytes
      Elke Dopp, Ursula von Recklinghausen, Louise M. Hartmann, Inga Stueckradt, Ilona Pollok, Sasan Rabieh, Liping Hao, Andreas Nussler, Cindy Katier, Alfred V. Hirner and Albert W. Rettenmeier
      Drug Metabolism and Disposition May 2008, 36 (5) 971-979; DOI: https://doi.org/10.1124/dmd.107.019034

W

  1. Wallace, Andrew D.

    1. Unique Transcription Start Sites and Distinct Promoter Regions Differentiate the Pregnane X Receptor (PXR) Isoforms PXR 1 and PXR 2
      Leslie M. Tompkins, Tim L. Sit and Andrew D. Wallace
      Drug Metabolism and Disposition May 2008, 36 (5) 923-929; DOI: https://doi.org/10.1124/dmd.107.018317

  2. Wen, Bo

    1. Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine
      Bo Wen, Li Ma, A. David Rodrigues and Mingshe Zhu
      Drug Metabolism and Disposition May 2008, 36 (5) 841-850; DOI: https://doi.org/10.1124/dmd.107.019471

Y

  1. Yamashita, Shinji

    1. Scaling of in Vitro Membrane Permeability to Predict P-glycoprotein-Mediated Drug Absorption in Vivo
      Yoshiyuki Shirasaka, Yoshie Masaoka, Makoto Kataoka, Shinji Sakuma and Shinji Yamashita
      Drug Metabolism and Disposition May 2008, 36 (5) 916-922; DOI: https://doi.org/10.1124/dmd.107.020040

  2. Yang, Kyung H.

    1. Time-Dependent Effects of Klebsiella Pneumoniae Endotoxin (KPLPS) on the Pharmacokinetics of Theophylline in Rats: Return of the Parameters in 96-Hour KPLPS Rats to the Control Levels
      Kyung H. Yang, Young S. Jung, Dae Y. Lee, Joo H. Lee, Young C. Kim and Myung G. Lee
      Drug Metabolism and Disposition May 2008, 36 (5) 811-815; DOI: https://doi.org/10.1124/dmd.107.018499

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
      Xianbin Tian, Brandon Swift, Maciej J. Zamek-Gliszczynski, Martin G. Belinsky, Gary D. Kruh and Kim L. R. Brouwer
      Drug Metabolism and Disposition May 2008, 36 (5) 911-915; DOI: https://doi.org/10.1124/dmd.107.019273

  2. Zhu, Mingshe

    1. Detection of Novel Reactive Metabolites of Trazodone: Evidence for CYP2D6-Mediated Bioactivation of m-Chlorophenylpiperazine
      Bo Wen, Li Ma, A. David Rodrigues and Mingshe Zhu
      Drug Metabolism and Disposition May 2008, 36 (5) 841-850; DOI: https://doi.org/10.1124/dmd.107.019471
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