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Drug Metabolism & Disposition

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Index by author

June 01, 2008; Volume 36,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Abdel-Tawab, Mona

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  2. Adachi, Yasuhisa

    1. You have access
      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
  3. Ahn, Hee-Jeong

    1. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  4. Akada, Mami

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  5. Aninat, Caroline

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  6. Annaert, Pieter P.

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
  7. Asanoma, Hisae

    1. You have access
      Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)
      Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
  8. Augustijns, Patrick

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646

B

  1. Bae, Soo Kyung

    1. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  2. Bagley, Rodney

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  3. Bahr, Ute

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  4. Bains, Onkar S.

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  5. Bauman, Jonathan N.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  6. Beijnen, J. H.

    1. You have access
      Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction
      S. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. Meijerman
      Drug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
  7. Benjamin, Daniel K.

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
  8. Bridges, Arlene

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646

C

  1. Carr, Brian A.

    1. You have access
      Comparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 Induction
      Niresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan Chu
      Drug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
  2. Castell, José V.

    1. You have access
      ATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress Responses
      Maya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro Jover
      Drug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
  3. Chen, Yong

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  4. Choi, Hoon

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  5. Chu, Xiaoyan

    1. You have access
      Comparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 Induction
      Niresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan Chu
      Drug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
  6. Cox, Loretta M.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545

D

  1. Daneshfar, Rambod

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  2. Decicco, Carl P.

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  3. Desai, Pankaj B.

    1. You have access
      Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors
      Anshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
  4. Duan, Jingwu

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  5. Dumont, Julie

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901

E

  1. Eckert, Gunter P.

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  2. Enokizono, Junichi

    1. You have access
      Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
      Junichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
  3. Evers, Raymond

    1. You have access
      Comparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 Induction
      Niresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan Chu
      Drug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677

F

  1. Fang, Lanyan

    1. You have access
      Predictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug Therapy
      Lanyan Fang and Duxin Sun
      Drug Metabolism and Disposition June 2008, 36 (6) 1153-1165; DOI: https://doi.org/10.1124/dmd.107.019182
  2. Fessard, Valérie

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  3. Frederick, Kosea S.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  4. Fricker, Gert

    1. You have access
      Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats
      Doreen Mitschke, Andreas Reichel, Gert Fricker and Ursula Moenning
      Drug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687

G

  1. Galinsky, Raymond E.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  2. Gan, Lian-Shen

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  3. Gao, Yan

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
  4. Garner, C. Edwin

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  5. Gavin, Patrick

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  6. Gay, John

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  7. Glaise, Denise

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  8. Gómez-Lechón, M. José

    1. You have access
      ATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress Responses
      Maya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro Jover
      Drug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
  9. Greene, Stephen

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  10. Grigliatti, Thomas A.

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  11. Guguen-Guillouzo, Christiane

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  12. Guillouzo, André

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  13. Gupta, Anshul

    1. You have access
      Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors
      Anshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689

H

  1. Hall, Stephen D.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  2. Hamman, Mitchell A.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  3. Hariparsad, Niresh

    1. You have access
      Comparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 Induction
      Niresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan Chu
      Drug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
  4. Harmsen, S.

    1. You have access
      Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction
      S. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. Meijerman
      Drug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
  5. Hashita, Tadahiro

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  6. Hsu, Fong Fu

    1. You have access
      N-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in Mouse
      Vijaya M. Lakshmi, Fong Fu Hsu and Terry V. Zenser
      Drug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166

I

  1. Iseki, Shoichi

    1. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  2. Ito, Sumiyo

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  3. Iwai, Megumi

    1. You have access
      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
  4. Iwatsubo, Takafumi

    1. You have access
      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669

J

  1. Jiyamapa-Serna, Vanida A.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  2. Jones, Kevin

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  3. Jossé, Rozenn

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  4. Jover, Ramiro

    1. You have access
      ATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress Responses
      Maya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro Jover
      Drug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380

K

  1. Kalgutkar, Amit S.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  2. Kamimura, Hidetaka

    1. You have access
      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
  3. Karas, Michael

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  4. Kato, Sayaka

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
  5. Kato, Yukio

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
    2. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  6. Kim, Hyunmi

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
    2. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  7. Kim, Jeong-Han

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  8. Kim, Kwon-Bok

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  9. Kimura, Robert E.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
  10. Kitamura, Ryuichi

    1. You have access
      Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)
      Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
  11. Klein, Jochen

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  12. Knights, Kathleen M.

    1. You have access
      The “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities
      Andrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
  13. Koster, A. S.

    1. You have access
      Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction
      S. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. Meijerman
      Drug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
  14. Krüger, Phillip

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  15. Ku, Hei-Young

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
    2. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  16. Kubo, Yoshiyuki

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
    2. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  17. Kusuhara, Hiroyuki

    1. You have access
      Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
      Junichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257

L

  1. Lai, Chii-Ming

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  2. Lakshmi, Vijaya M.

    1. You have access
      N-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in Mouse
      Vijaya M. Lakshmi, Fong Fu Hsu and Terry V. Zenser
      Drug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166
  3. Lee, Choong-Hwan

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  4. Lee, Frank W.

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  5. Lee, Hye Suk

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  6. Lin, Jianrong

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  7. Liu, Kwang-Hyeon

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
    2. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  8. Luo, Gang

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038

M

  1. Mackenzie, Peter I.

    1. You have access
      The “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities
      Andrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
  2. Maduskuie, Thomas

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  3. McGinnity, Dermot F.

    1. You have access
      Integrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug Interactions
      Dermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. Riley
      Drug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
  4. Mealey, Katrina L.

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  5. Meijerman, I.

    1. You have access
      Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction
      S. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. Meijerman
      Drug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
  6. Mercer, Stephen E.

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  7. Miners, John O.

    1. You have access
      The “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities
      Andrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
  8. Mitschke, Doreen

    1. You have access
      Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats
      Doreen Mitschke, Andreas Reichel, Gert Fricker and Ursula Moenning
      Drug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
  9. Moenning, Ursula

    1. You have access
      Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats
      Doreen Mitschke, Andreas Reichel, Gert Fricker and Ursula Moenning
      Drug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
  10. Moon, Joon-Kwan

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  11. Morel, Fabrice

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  12. Mugundu, Ganesh M.

    1. You have access
      Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors
      Anshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
  13. Müller, Walter E.

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  14. Murphy, Patrick J.

    1. You have access
      The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983
      Patrick J. Murphy
      Drug Metabolism and Disposition June 2008, 36 (6) 981-985; DOI: https://doi.org/10.1124/dmd.108.021113

N

  1. Nagayama, Sekio

    1. You have access
      Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)
      Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
  2. Nakajima, Asuka

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  3. Nelson, Frederick

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  4. Nemoto, Nobuo

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729

O

  1. Obach, Ronald S.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  2. Oh, Minkyung

    1. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  3. Ose, Atsushi

    1. You have access
      Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
      Junichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
  4. Otagiri, Masaki

    1. You have access
      Identification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)
      Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki Otagiri
      Drug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877

P

  1. Park, Byeoung-Soo

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  2. Park, Soo-Jin

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
  3. Pascual, Maya

    1. You have access
      ATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress Responses
      Maya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro Jover
      Drug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
  4. Pfeifer, Tom A.

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  5. Poul, Jean-Michel

    1. You have access
      Long-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity Studies
      Rozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André Guillouzo
      Drug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
  6. Prakash, Shimoga

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038

Q

  1. Qian, Mingxin

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  2. Quinney, Sara K.

    1. You have access
      Hydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in Rats
      Sara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. Kimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644

R

  1. Reichel, Andreas

    1. You have access
      Characterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female Rats
      Doreen Mitschke, Andreas Reichel, Gert Fricker and Ursula Moenning
      Drug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
  2. Reid, Ronald E.

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  3. Riggs, K. Wayne

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  4. Riley, Robert J.

    1. You have access
      Integrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug Interactions
      Dermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. Riley
      Drug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
  5. Rowland, Andrew

    1. You have access
      The “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities
      Andrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105

S

  1. Sai, Yoshimichi

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
  2. Sakuma, Tsutomu

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  3. Sawant, Aarti

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  4. Schellens, J. H. M.

    1. You have access
      Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction
      S. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. Meijerman
      Drug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
  5. Schinkel, Alfred H.

    1. You have access
      Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
      Junichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
  6. Schmidt, Kari

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
  7. Schubert-Zsilavecz, Manfred

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
  8. Seo, Kyung-Ah

    1. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  9. Shen, Huey-Shin

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  10. Shin, Jae-Gook

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
    2. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  11. Shon, Ji-Hong

    1. You have access
      The Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and Vardenafil
      Hei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
  12. Silver, David L.

    1. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  13. Solon, Eric

    1. You have access
      Role of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in Rodents
      C. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. Lee
      Drug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
  14. Sugiura, Tomoko

    1. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  15. Sugiyama, Yuichi

    1. You have access
      Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds
      Junichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
  16. Sun, Duxin

    1. You have access
      Predictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug Therapy
      Lanyan Fang and Duxin Sun
      Drug Metabolism and Disposition June 2008, 36 (6) 1153-1165; DOI: https://doi.org/10.1124/dmd.107.019182

T

  1. Takahara, Seiko

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
  2. Takahashi, Ryan H.

    1. You have access
      Aldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in Vitro
      Ryan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne Riggs
      Drug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
  3. Takesako, Hidekazu

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  4. Tamai, Ikumi

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
  5. Thakker, Dhiren R.

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
  6. Thummel, Kenneth E.

    1. You have access
      Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors
      Anshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
  7. Tsuji, Akira

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
    2. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  8. Tucker, James

    1. You have access
      Integrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug Interactions
      Dermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. Riley
      Drug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
  9. Tucker, Russ

    1. You have access
      P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model
      Katrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick Nelson
      Drug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978

U

  1. Umehara, Ken-ichi

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      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
  2. Unadkat, Jashvant D.

    1. You have access
      Intestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease Inhibitors
      Anshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
  3. Usui, Takashi

    1. You have access
      Hepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and Humans
      Ken-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka Kamimura
      Drug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669

V

  1. Volmer, Dietrich A.

    1. You have access
      Metabolism of Boswellic Acids in Vitro and in Vivo
      Phillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-Tawab
      Drug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424

W

  1. Wakayama, Tomohiko

    1. You have access
      PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice
      Tomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
  2. Walsky, Robert L.

    1. You have access
      Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
      Jonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. Kalgutkar
      Drug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
  3. Waters, Nigel J.

    1. You have access
      Integrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug Interactions
      Dermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. Riley
      Drug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446

Y

  1. Yabuuchi, Hikaru

    1. You have access
      Involvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam Antibiotics
      Yukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira Tsuji
      Drug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
  2. Yamahara, Hirofumi

    1. You have access
      Forkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 Gene
      Tadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo Nemoto
      Drug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
  3. Yanni, Souzan B.

    1. You have access
      Role of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver Microsomes
      Souzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. Thakker
      Drug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
  4. Yea, Sung Su

    1. You have access
      Identification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and China
      Hyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon Liu
      Drug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612

Z

  1. Zenser, Terry V.

    1. You have access
      N-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in Mouse
      Vijaya M. Lakshmi, Fong Fu Hsu and Terry V. Zenser
      Drug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166
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Drug Metabolism and Disposition: 36 (6)
Drug Metabolism and Disposition
Vol. 36, Issue 6
1 Jun 2008
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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