Index by author
June 01, 2008; Volume 36,Issue 6
A
Abdel-Tawab, Mona
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Adachi, Yasuhisa
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
Ahn, Hee-Jeong
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Akada, Mami
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Aninat, Caroline
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Annaert, Pieter P.
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
Asanoma, Hisae
- You have accessIdentification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki OtagiriDrug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
Augustijns, Patrick
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
B
Bae, Soo Kyung
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Bagley, Rodney
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Bahr, Ute
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Bains, Onkar S.
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Bauman, Jonathan N.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Beijnen, J. H.
- You have accessComparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 InductionS. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. MeijermanDrug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
Benjamin, Daniel K.
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
Bridges, Arlene
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
C
Carr, Brian A.
- You have accessComparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 InductionNiresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan ChuDrug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
Castell, José V.
- You have accessATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress ResponsesMaya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro JoverDrug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
Chen, Yong
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Choi, Hoon
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Chu, Xiaoyan
- You have accessComparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 InductionNiresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan ChuDrug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
Cox, Loretta M.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
D
Daneshfar, Rambod
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Decicco, Carl P.
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Desai, Pankaj B.
- You have accessIntestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease InhibitorsAnshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. UnadkatDrug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
Duan, Jingwu
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Dumont, Julie
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
E
Eckert, Gunter P.
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Enokizono, Junichi
- You have accessQuantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic CompoundsJunichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi SugiyamaDrug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
Evers, Raymond
- You have accessComparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 InductionNiresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan ChuDrug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
F
Fang, Lanyan
- You have accessPredictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug TherapyLanyan Fang and Duxin SunDrug Metabolism and Disposition June 2008, 36 (6) 1153-1165; DOI: https://doi.org/10.1124/dmd.107.019182
Fessard, Valérie
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Frederick, Kosea S.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Fricker, Gert
- You have accessCharacterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female RatsDoreen Mitschke, Andreas Reichel, Gert Fricker and Ursula MoenningDrug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
G
Galinsky, Raymond E.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Gan, Lian-Shen
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Gao, Yan
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
Garner, C. Edwin
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Gavin, Patrick
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Gay, John
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Glaise, Denise
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Gómez-Lechón, M. José
- You have accessATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress ResponsesMaya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro JoverDrug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
Greene, Stephen
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Grigliatti, Thomas A.
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Guguen-Guillouzo, Christiane
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Guillouzo, André
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Gupta, Anshul
- You have accessIntestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease InhibitorsAnshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. UnadkatDrug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
H
Hall, Stephen D.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Hamman, Mitchell A.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Hariparsad, Niresh
- You have accessComparison of Immortalized Fa2N-4 Cells and Human Hepatocytes as in Vitro Models for Cytochrome P450 InductionNiresh Hariparsad, Brian A. Carr, Raymond Evers and Xiaoyan ChuDrug Metabolism and Disposition June 2008, 36 (6) 1046-1055; DOI: https://doi.org/10.1124/dmd.108.020677
Harmsen, S.
- You have accessComparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 InductionS. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. MeijermanDrug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
Hashita, Tadahiro
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Hsu, Fong Fu
- You have accessN-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in MouseVijaya M. Lakshmi, Fong Fu Hsu and Terry V. ZenserDrug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166
I
Iseki, Shoichi
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Ito, Sumiyo
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Iwai, Megumi
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
Iwatsubo, Takafumi
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
J
Jiyamapa-Serna, Vanida A.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Jones, Kevin
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Jossé, Rozenn
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Jover, Ramiro
- You have accessATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress ResponsesMaya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro JoverDrug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
K
Kalgutkar, Amit S.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Kamimura, Hidetaka
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
Karas, Michael
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Kato, Sayaka
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
Kato, Yukio
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Kim, Hyunmi
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Kim, Jeong-Han
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Kim, Kwon-Bok
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Kimura, Robert E.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
Kitamura, Ryuichi
- You have accessIdentification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki OtagiriDrug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
Klein, Jochen
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Knights, Kathleen M.
- You have accessThe “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 ActivitiesAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
Koster, A. S.
- You have accessComparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 InductionS. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. MeijermanDrug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
Krüger, Phillip
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Ku, Hei-Young
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Kubo, Yoshiyuki
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Kusuhara, Hiroyuki
- You have accessQuantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic CompoundsJunichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi SugiyamaDrug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
L
Lai, Chii-Ming
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Lakshmi, Vijaya M.
- You have accessN-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in MouseVijaya M. Lakshmi, Fong Fu Hsu and Terry V. ZenserDrug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166
Lee, Choong-Hwan
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Lee, Frank W.
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Lee, Hye Suk
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Lin, Jianrong
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Liu, Kwang-Hyeon
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Luo, Gang
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
M
Mackenzie, Peter I.
- You have accessThe “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 ActivitiesAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
Maduskuie, Thomas
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
McGinnity, Dermot F.
- You have accessIntegrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug InteractionsDermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. RileyDrug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
Mealey, Katrina L.
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Meijerman, I.
- You have accessComparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 InductionS. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. MeijermanDrug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
Mercer, Stephen E.
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Miners, John O.
- You have accessThe “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 ActivitiesAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
Mitschke, Doreen
- You have accessCharacterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female RatsDoreen Mitschke, Andreas Reichel, Gert Fricker and Ursula MoenningDrug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
Moenning, Ursula
- You have accessCharacterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female RatsDoreen Mitschke, Andreas Reichel, Gert Fricker and Ursula MoenningDrug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
Moon, Joon-Kwan
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Morel, Fabrice
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Mugundu, Ganesh M.
- You have accessIntestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease InhibitorsAnshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. UnadkatDrug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
Müller, Walter E.
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Murphy, Patrick J.
- You have accessThe Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 2, 1959–1983Patrick J. MurphyDrug Metabolism and Disposition June 2008, 36 (6) 981-985; DOI: https://doi.org/10.1124/dmd.108.021113
N
Nagayama, Sekio
- You have accessIdentification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki OtagiriDrug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
Nakajima, Asuka
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Nelson, Frederick
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Nemoto, Nobuo
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
O
Obach, Ronald S.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Oh, Minkyung
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Ose, Atsushi
- You have accessQuantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic CompoundsJunichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi SugiyamaDrug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
Otagiri, Masaki
- You have accessIdentification of Human Liver Cytochrome P450 Isoforms Involved in Autoinduced Metabolism of the Antiangiogenic Agent (Z)-5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic Acid (TSU-68)Ryuichi Kitamura, Hisae Asanoma, Sekio Nagayama and Masaki OtagiriDrug Metabolism and Disposition June 2008, 36 (6) 1003-1009; DOI: https://doi.org/10.1124/dmd.107.019877
P
Park, Byeoung-Soo
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Park, Soo-Jin
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Pascual, Maya
- You have accessATF5 Is a Highly Abundant Liver-Enriched Transcription Factor that Cooperates with Constitutive Androstane Receptor in the Transactivation of CYP2B6: Implications in Hepatic Stress ResponsesMaya Pascual, M. José Gómez-Lechón, José V. Castell and Ramiro JoverDrug Metabolism and Disposition June 2008, 36 (6) 1063-1072; DOI: https://doi.org/10.1124/dmd.107.019380
Pfeifer, Tom A.
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Poul, Jean-Michel
- You have accessLong-Term Functional Stability of Human HepaRG Hepatocytes and Use for Chronic Toxicity and Genotoxicity StudiesRozenn Jossé, Caroline Aninat, Denise Glaise, Julie Dumont, Valérie Fessard, Fabrice Morel, Jean-Michel Poul, Christiane Guguen-Guillouzo and André GuillouzoDrug Metabolism and Disposition June 2008, 36 (6) 1111-1118; DOI: https://doi.org/10.1124/dmd.107.019901
Prakash, Shimoga
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Q
Qian, Mingxin
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Quinney, Sara K.
- You have accessHydroxyitraconazole, Formed During Intestinal First-Pass Metabolism of Itraconazole, Controls the Time Course of Hepatic CYP3A Inhibition and the Bioavailability of Itraconazole in RatsSara K. Quinney, Raymond E. Galinsky, Vanida A. Jiyamapa-Serna, Yong Chen, Mitchell A. Hamman, Stephen D. Hall and Robert E. KimuraDrug Metabolism and Disposition June 2008, 36 (6) 1097-1101; DOI: https://doi.org/10.1124/dmd.108.020644
R
Reichel, Andreas
- You have accessCharacterization of Cytochrome P450 Protein Expression along the Entire Length of the Intestine of Male and Female RatsDoreen Mitschke, Andreas Reichel, Gert Fricker and Ursula MoenningDrug Metabolism and Disposition June 2008, 36 (6) 1039-1045; DOI: https://doi.org/10.1124/dmd.107.019687
Reid, Ronald E.
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Riggs, K. Wayne
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Riley, Robert J.
- You have accessIntegrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug InteractionsDermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. RileyDrug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
Rowland, Andrew
- You have accessThe “Albumin Effect” and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 ActivitiesAndrew Rowland, Kathleen M. Knights, Peter I. Mackenzie and John O. MinersDrug Metabolism and Disposition June 2008, 36 (6) 1056-1062; DOI: https://doi.org/10.1124/dmd.108.021105
S
Sai, Yoshimichi
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
Sakuma, Tsutomu
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Sawant, Aarti
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Schellens, J. H. M.
- You have accessComparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 InductionS. Harmsen, A. S. Koster, J. H. Beijnen, J. H. M. Schellens and I. MeijermanDrug Metabolism and Disposition June 2008, 36 (6) 1166-1171; DOI: https://doi.org/10.1124/dmd.107.017335
Schinkel, Alfred H.
- You have accessQuantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic CompoundsJunichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi SugiyamaDrug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
Schmidt, Kari
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
Schubert-Zsilavecz, Manfred
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
Seo, Kyung-Ah
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Shen, Huey-Shin
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Shin, Jae-Gook
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Shon, Ji-Hong
- You have accessThe Contributions of Cytochromes P450 3A4 and 3A5 to the Metabolism of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Udenafil, and VardenafilHei-Young Ku, Hee-Jeong Ahn, Kyung-Ah Seo, Hyunmi Kim, Minkyung Oh, Soo Kyung Bae, Jae-Gook Shin, Ji-Hong Shon and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 986-990; DOI: https://doi.org/10.1124/dmd.107.020099
Silver, David L.
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Solon, Eric
- You have accessRole of P-Glycoprotein and the Intestine in the Excretion of DPC 333 [(2R)-2-{(3R)-3-Amino-3-[4-(2-methylquinolin-4-ylmethoxy)phenyl]-2-oxopyrrolidin-1-yl}-N-hydroxy-4-methylpentanamide] in RodentsC. Edwin Garner, Eric Solon, Chii-Ming Lai, Jianrong Lin, Gang Luo, Kevin Jones, Jingwu Duan, Carl P. Decicco, Thomas Maduskuie, Stephen E. Mercer, Lian-Shen Gan, Mingxin Qian, Shimoga Prakash, Huey-Shin Shen and Frank W. LeeDrug Metabolism and Disposition June 2008, 36 (6) 1102-1110; DOI: https://doi.org/10.1124/dmd.107.017038
Sugiura, Tomoko
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Sugiyama, Yuichi
- You have accessQuantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic CompoundsJunichi Enokizono, Hiroyuki Kusuhara, Atsushi Ose, Alfred H. Schinkel and Yuichi SugiyamaDrug Metabolism and Disposition June 2008, 36 (6) 995-1002; DOI: https://doi.org/10.1124/dmd.107.019257
Sun, Duxin
- You have accessPredictive Physiologically Based Pharmacokinetic Model for Antibody-Directed Enzyme Prodrug TherapyLanyan Fang and Duxin SunDrug Metabolism and Disposition June 2008, 36 (6) 1153-1165; DOI: https://doi.org/10.1124/dmd.107.019182
T
Takahara, Seiko
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
Takahashi, Ryan H.
- You have accessAldo-Keto Reductase 1C2 Fails to Metabolize Doxorubicin and Daunorubicin in VitroRyan H. Takahashi, Onkar S. Bains, Tom A. Pfeifer, Thomas A. Grigliatti, Ronald E. Reid and K. Wayne RiggsDrug Metabolism and Disposition June 2008, 36 (6) 991-994; DOI: https://doi.org/10.1124/dmd.108.020388
Takesako, Hidekazu
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Tamai, Ikumi
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
Thakker, Dhiren R.
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
Thummel, Kenneth E.
- You have accessIntestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease InhibitorsAnshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. UnadkatDrug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
Tsuji, Akira
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Tucker, James
- You have accessIntegrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug InteractionsDermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. RileyDrug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
Tucker, Russ
- You have accessP-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout ModelKatrina L. Mealey, Stephen Greene, Rodney Bagley, John Gay, Russ Tucker, Patrick Gavin, Kari Schmidt and Frederick NelsonDrug Metabolism and Disposition June 2008, 36 (6) 1073-1079; DOI: https://doi.org/10.1124/dmd.107.018978
U
Umehara, Ken-ichi
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
Unadkat, Jashvant D.
- You have accessIntestinal Human Colon Adenocarcinoma Cell Line LS180 Is an Excellent Model to Study Pregnane X Receptor, but Not Constitutive Androstane Receptor, Mediated CYP3A4 and Multidrug Resistance Transporter 1 Induction: Studies with Anti-Human Immunodeficiency Virus Protease InhibitorsAnshul Gupta, Ganesh M. Mugundu, Pankaj B. Desai, Kenneth E. Thummel and Jashvant D. UnadkatDrug Metabolism and Disposition June 2008, 36 (6) 1172-1180; DOI: https://doi.org/10.1124/dmd.107.018689
Usui, Takashi
- You have accessHepatic Uptake and Excretion of (–)-N-{2-[(R)-3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a Novel If Channel Inhibitor, in Rats and HumansKen-ichi Umehara, Megumi Iwai, Yasuhisa Adachi, Takafumi Iwatsubo, Takashi Usui and Hidetaka KamimuraDrug Metabolism and Disposition June 2008, 36 (6) 1030-1038; DOI: https://doi.org/10.1124/dmd.108.020669
V
Volmer, Dietrich A.
- You have accessMetabolism of Boswellic Acids in Vitro and in VivoPhillip Krüger, Rambod Daneshfar, Gunter P. Eckert, Jochen Klein, Dietrich A. Volmer, Ute Bahr, Walter E. Müller, Michael Karas, Manfred Schubert-Zsilavecz and Mona Abdel-TawabDrug Metabolism and Disposition June 2008, 36 (6) 1135-1142; DOI: https://doi.org/10.1124/dmd.107.018424
W
Wakayama, Tomohiko
- You have accessPDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in MiceTomoko Sugiura, Yukio Kato, Tomohiko Wakayama, David L. Silver, Yoshiyuki Kubo, Shoichi Iseki and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1181-1188; DOI: https://doi.org/10.1124/dmd.107.020321
Walsky, Robert L.
- You have accessComparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed DrugJonathan N. Bauman, Kosea S. Frederick, Aarti Sawant, Robert L. Walsky, Loretta M. Cox, Ronald S. Obach and Amit S. KalgutkarDrug Metabolism and Disposition June 2008, 36 (6) 1016-1029; DOI: https://doi.org/10.1124/dmd.108.020545
Waters, Nigel J.
- You have accessIntegrated in Vitro Analysis for the in Vivo Prediction of Cytochrome P450-Mediated Drug-Drug InteractionsDermot F. McGinnity, Nigel J. Waters, James Tucker and Robert J. RileyDrug Metabolism and Disposition June 2008, 36 (6) 1126-1134; DOI: https://doi.org/10.1124/dmd.108.020446
Y
Yabuuchi, Hikaru
- You have accessInvolvement of Multidrug Resistance-Associated Protein 2 (Abcc2) in Molecular Weight-Dependent Biliary Excretion of β-Lactam AntibioticsYukio Kato, Seiko Takahara, Sayaka Kato, Yoshiyuki Kubo, Yoshimichi Sai, Ikumi Tamai, Hikaru Yabuuchi and Akira TsujiDrug Metabolism and Disposition June 2008, 36 (6) 1088-1096; DOI: https://doi.org/10.1124/dmd.107.019125
Yamahara, Hirofumi
- You have accessForkhead Box A2–Mediated Regulation of Female-Predominant Expression of the Mouse Cyp2b9 GeneTadahiro Hashita, Tsutomu Sakuma, Mami Akada, Asuka Nakajima, Hirofumi Yamahara, Sumiyo Ito, Hidekazu Takesako and Nobuo NemotoDrug Metabolism and Disposition June 2008, 36 (6) 1080-1087; DOI: https://doi.org/10.1124/dmd.107.019729
Yanni, Souzan B.
- You have accessRole of Flavin-Containing Monooxygenase in Oxidative Metabolism of Voriconazole by Human Liver MicrosomesSouzan B. Yanni, Pieter P. Annaert, Patrick Augustijns, Arlene Bridges, Yan Gao, Daniel K. Benjamin and Dhiren R. ThakkerDrug Metabolism and Disposition June 2008, 36 (6) 1119-1125; DOI: https://doi.org/10.1124/dmd.107.019646
Yea, Sung Su
- You have accessIdentification and Characterization of Potent CYP2B6 Inhibitors in Woohwangcheongsimwon Suspension, an Herbal Preparation Used in the Treatment and Prevention of Apoplexy in Korea and ChinaHyunmi Kim, Kwon-Bok Kim, Hei-Young Ku, Soo-Jin Park, Hoon Choi, Joon-Kwan Moon, Byeoung-Soo Park, Jeong-Han Kim, Sung Su Yea, Choong-Hwan Lee, Hye Suk Lee, Jae-Gook Shin and Kwang-Hyeon LiuDrug Metabolism and Disposition June 2008, 36 (6) 1010-1015; DOI: https://doi.org/10.1124/dmd.107.019612
Z
Zenser, Terry V.
- You have accessN-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in MouseVijaya M. Lakshmi, Fong Fu Hsu and Terry V. ZenserDrug Metabolism and Disposition June 2008, 36 (6) 1143-1152; DOI: https://doi.org/10.1124/dmd.107.019166
In this issue

Advertisement