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Drug Metabolism & Disposition

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Index by author

July 01, 2008; Volume 36,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. A, Jiye

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  2. Adachi, Isao

    1. You have access
      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
      Naoko Yoshida, Tappei Takada, Yoshikazu Yamamura, Isao Adachi, Hiroshi Suzuki and Junichi Kawakami
      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513
  3. Ahn, Choong Y.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  4. Ai, Hua

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  5. Allentoff, Alban

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  6. Andersson, Tommy B.

    1. You have access
      Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies
      Kajsa P. Kanebratt and Tommy B. Andersson
      Drug Metabolism and Disposition July 2008, 36 (7) 1444-1452; DOI: https://doi.org/10.1124/dmd.107.020016
  7. Annaert, Pieter

    1. You have access
      Cellular Accumulation of Cholyl-Glycylamido-Fluorescein in Sandwich-Cultured Rat Hepatocytes: Kinetic Characterization, Transport Mechanisms, and Effect of Human Immunodeficiency Virus Protease Inhibitors
      Zhi-wei Ye, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2008, 36 (7) 1315-1321; DOI: https://doi.org/10.1124/dmd.107.019398
  8. Aparicio-Fabre, Rosaura

    1. You have access
      Osmotic Regulation of a Novel Flavin-Containing Monooxygenase in Primary Cultured Cells from Rainbow Trout (Oncorhynchus mykiss)
      Gabriela Rodríguez-Fuentes, Rosaura Aparicio-Fabre, Qi Li and Daniel Schlenk
      Drug Metabolism and Disposition July 2008, 36 (7) 1212-1217; DOI: https://doi.org/10.1124/dmd.107.019968
  9. Arora, Vinod K.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  10. Augustijns, Patrick

    1. You have access
      Cellular Accumulation of Cholyl-Glycylamido-Fluorescein in Sandwich-Cultured Rat Hepatocytes: Kinetic Characterization, Transport Mechanisms, and Effect of Human Immunodeficiency Virus Protease Inhibitors
      Zhi-wei Ye, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2008, 36 (7) 1315-1321; DOI: https://doi.org/10.1124/dmd.107.019398

B

  1. Bae, Soo K.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  2. Balani, Suresh K.

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole
      Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
    2. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. III. In Vitro-in Vivo Correlation with Fluconazole
      Chuang Lu, Cicely Berg, Shimoga R. Prakash, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1261-1266; DOI: https://doi.org/10.1124/dmd.107.019000
  3. Barros, Anthony

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  4. Berg, Cicely

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole
      Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
    2. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. III. In Vitro-in Vivo Correlation with Fluconazole
      Chuang Lu, Cicely Berg, Shimoga R. Prakash, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1261-1266; DOI: https://doi.org/10.1124/dmd.107.019000
  5. Blackwood-Chirchir, Anne

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  6. Bonacorsi, Samuel J.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  7. Brundage, Richard C.

    1. You have access
      Differential Genotype Dependent Inhibition of CYP2C9 in Humans
      Vikas Kumar, Richard C. Brundage, William S. Oetting, Ilo E. Leppik and Timothy S. Tracy
      Drug Metabolism and Disposition July 2008, 36 (7) 1242-1248; DOI: https://doi.org/10.1124/dmd.108.020396
  8. Bui, Peter H.

    1. You have access
      The Mibefradil Derivative NNC55-0396, a Specific T-Type Calcium Channel Antagonist, Exhibits Less CYP3A4 Inhibition than Mibefradil
      Peter H. Bui, Arnulfo Quesada, Adrian Handforth and Oliver Hankinson
      Drug Metabolism and Disposition July 2008, 36 (7) 1291-1299; DOI: https://doi.org/10.1124/dmd.107.020115

C

  1. Carreiro, Samantha

    1. You have access
      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121
  2. Christensen, James G.

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  3. Christopher, Lisa J.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  4. Cui, Donghui

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267

D

  1. Dalvie, Deepak

    1. You have access
      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  2. Deese, Alan

    1. You have access
      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  3. Dickmann, Leslie J.

    1. You have access
      Functional Expression and Comparative Characterization of Nine Murine Cytochromes P450 by Fluorescent Inhibition Screening
      Lesley A. McLaughlin, Leslie J. Dickmann, C. Roland Wolf and Colin J. Henderson
      Drug Metabolism and Disposition July 2008, 36 (7) 1322-1331; DOI: https://doi.org/10.1124/dmd.108.021261

F

  1. Farid, Nagy A.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  2. Fitzsimmons, Patrick N.

    1. You have access
      Use of Online Microdialysis Sampling to Determine the in Vivo Rate of Phenol Glucuronidation in Rainbow Trout
      John W. Nichols, Alex D. Hoffman, Patrick N. Fitzsimmons, Gregory J. Lien and Correne T. Jenson
      Drug Metabolism and Disposition July 2008, 36 (7) 1406-1413; DOI: https://doi.org/10.1124/dmd.107.020123
  3. Fletcher, Anthony M.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  4. Fricker, Gert

    1. You have access
      Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats
      Caroline MacLean, Ulla Moenning, Andreas Reichel and Gert Fricker
      Drug Metabolism and Disposition July 2008, 36 (7) 1249-1254; DOI: https://doi.org/10.1124/dmd.108.020859
  5. Fukuda, Hajime

    1. You have access
      Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes
      Hajime Fukuda, Rikiya Ohashi, Minoru Tsuda-Tsukimoto and Ikumi Tamai
      Drug Metabolism and Disposition July 2008, 36 (7) 1275-1282; DOI: https://doi.org/10.1124/dmd.107.019026

G

  1. Galbraith, Susan

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  2. Gale, David

    1. You have access
      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121
  3. Galetin, Aleksandra

    1. You have access
      Hepatocellular Binding of Drugs: Correction for Unbound Fraction in Hepatocyte Incubations Using Microsomal Binding or Drug Lipophilicity Data
      Peter J. Kilford, Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2008, 36 (7) 1194-1197; DOI: https://doi.org/10.1124/dmd.108.020834
    2. You have access
      Comparative Analysis of CYP3A Heteroactivation by Steroid Hormones and Flavonoids in Different in Vitro Systems and Potential in Vivo Implications
      Jamie Henshall, Aleksandra Galetin, Anthony Harrison and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1332-1340; DOI: https://doi.org/10.1124/dmd.108.021279
  4. Gardiner, Philip

    1. You have access
      Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
      Stuart W. Paine, Alison J. Parker, Philip Gardiner, Peter J. H. Webborn and Robert J. Riley
      Drug Metabolism and Disposition July 2008, 36 (7) 1365-1374; DOI: https://doi.org/10.1124/dmd.107.019455
  5. Gardner, Mark J.

    1. You have access
      Disposition of Lasofoxifene, a Next-Generation Selective Estrogen Receptor Modulator, in Healthy Male Subjects
      Chandra Prakash, Kim A. Johnson and Mark J. Gardner
      Drug Metabolism and Disposition July 2008, 36 (7) 1218-1226; DOI: https://doi.org/10.1124/dmd.108.020404
  6. Garmire, Lana X.

    1. You have access
      In Silico Methods for Unraveling the Mechanistic Complexities of Intestinal Absorption: Metabolism-Efflux Transport Interactions
      Lana X. Garmire and C. Anthony Hunt
      Drug Metabolism and Disposition July 2008, 36 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.107.020164
  7. Generaux, Grant T.

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198
  8. Gertz, Michael

    1. You have access
      Hepatocellular Binding of Drugs: Correction for Unbound Fraction in Hepatocyte Incubations Using Microsomal Binding or Drug Lipophilicity Data
      Peter J. Kilford, Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2008, 36 (7) 1194-1197; DOI: https://doi.org/10.1124/dmd.108.020834

H

  1. Handforth, Adrian

    1. You have access
      The Mibefradil Derivative NNC55-0396, a Specific T-Type Calcium Channel Antagonist, Exhibits Less CYP3A4 Inhibition than Mibefradil
      Peter H. Bui, Arnulfo Quesada, Adrian Handforth and Oliver Hankinson
      Drug Metabolism and Disposition July 2008, 36 (7) 1291-1299; DOI: https://doi.org/10.1124/dmd.107.020115
  2. Hankinson, Oliver

    1. You have access
      The Mibefradil Derivative NNC55-0396, a Specific T-Type Calcium Channel Antagonist, Exhibits Less CYP3A4 Inhibition than Mibefradil
      Peter H. Bui, Arnulfo Quesada, Adrian Handforth and Oliver Hankinson
      Drug Metabolism and Disposition July 2008, 36 (7) 1291-1299; DOI: https://doi.org/10.1124/dmd.107.020115
  3. Hao, Haiping

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  4. Harrison, Anthony

    1. You have access
      Comparative Analysis of CYP3A Heteroactivation by Steroid Hormones and Flavonoids in Different in Vitro Systems and Potential in Vivo Implications
      Jamie Henshall, Aleksandra Galetin, Anthony Harrison and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1332-1340; DOI: https://doi.org/10.1124/dmd.108.021279
  5. Hatsis, Panos

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole
      Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
  6. He, Kan

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  7. Henderson, Colin J.

    1. You have access
      Functional Expression and Comparative Characterization of Nine Murine Cytochromes P450 by Fluorescent Inhibition Screening
      Lesley A. McLaughlin, Leslie J. Dickmann, C. Roland Wolf and Colin J. Henderson
      Drug Metabolism and Disposition July 2008, 36 (7) 1322-1331; DOI: https://doi.org/10.1124/dmd.108.021261
  8. Henshall, Jamie

    1. You have access
      Comparative Analysis of CYP3A Heteroactivation by Steroid Hormones and Flavonoids in Different in Vitro Systems and Potential in Vivo Implications
      Jamie Henshall, Aleksandra Galetin, Anthony Harrison and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1332-1340; DOI: https://doi.org/10.1124/dmd.108.021279
  9. Hoffman, Alex D.

    1. You have access
      Use of Online Microdialysis Sampling to Determine the in Vivo Rate of Phenol Glucuronidation in Rainbow Trout
      John W. Nichols, Alex D. Hoffman, Patrick N. Fitzsimmons, Gregory J. Lien and Correne T. Jenson
      Drug Metabolism and Disposition July 2008, 36 (7) 1406-1413; DOI: https://doi.org/10.1124/dmd.107.020123
  10. Horie, Toru

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  11. Houston, J. Brian

    1. You have access
      Hepatocellular Binding of Drugs: Correction for Unbound Fraction in Hepatocyte Incubations Using Microsomal Binding or Drug Lipophilicity Data
      Peter J. Kilford, Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2008, 36 (7) 1194-1197; DOI: https://doi.org/10.1124/dmd.108.020834
    2. You have access
      Comparative Analysis of CYP3A Heteroactivation by Steroid Hormones and Flavonoids in Different in Vitro Systems and Potential in Vivo Implications
      Jamie Henshall, Aleksandra Galetin, Anthony Harrison and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1332-1340; DOI: https://doi.org/10.1124/dmd.108.021279
    3. You have access
      Rate-Limiting Steps in Hepatic Drug Clearance: Comparison of Hepatocellular Uptake and Metabolism with Microsomal Metabolism of Saquinavir, Nelfinavir, and Ritonavir
      Alison J. Parker and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1375-1384; DOI: https://doi.org/10.1124/dmd.108.020917
  12. Humphreys, W. Griffith

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  13. Hunt, C. Anthony

    1. You have access
      In Silico Methods for Unraveling the Mechanistic Complexities of Intestinal Absorption: Metabolism-Efflux Transport Interactions
      Lana X. Garmire and C. Anthony Hunt
      Drug Metabolism and Disposition July 2008, 36 (7) 1414-1424; DOI: https://doi.org/10.1124/dmd.107.020164

I

  1. Iizuka, Seiichi

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  2. Imamura, Sachiko

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  3. Inoue, Makoto

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  4. Inoue, Tae

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  5. Iyer, Ramaswamy A.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267

J

  1. Jenson, Correne T.

    1. You have access
      Use of Online Microdialysis Sampling to Determine the in Vivo Rate of Phenol Glucuronidation in Rainbow Trout
      John W. Nichols, Alex D. Hoffman, Patrick N. Fitzsimmons, Gregory J. Lien and Correne T. Jenson
      Drug Metabolism and Disposition July 2008, 36 (7) 1406-1413; DOI: https://doi.org/10.1124/dmd.107.020123
  2. Johnson, Kim A.

    1. You have access
      Disposition of Lasofoxifene, a Next-Generation Selective Estrogen Receptor Modulator, in Healthy Male Subjects
      Chandra Prakash, Kim A. Johnson and Mark J. Gardner
      Drug Metabolism and Disposition July 2008, 36 (7) 1218-1226; DOI: https://doi.org/10.1124/dmd.108.020404
  3. Jones, Karen O.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  4. Jung, Young S.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442

K

  1. Kanebratt, Kajsa P.

    1. You have access
      Evaluation of HepaRG Cells as an in Vitro Model for Human Drug Metabolism Studies
      Kajsa P. Kanebratt and Tommy B. Andersson
      Drug Metabolism and Disposition July 2008, 36 (7) 1444-1452; DOI: https://doi.org/10.1124/dmd.107.020016
  2. Kang, Ping

    1. You have access
      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  3. Kawakami, Junichi

    1. You have access
      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
      Naoko Yoshida, Tappei Takada, Yoshikazu Yamamura, Isao Adachi, Hiroshi Suzuki and Junichi Kawakami
      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513
  4. Kazui, Miho

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  5. Kilford, Peter J.

    1. You have access
      Hepatocellular Binding of Drugs: Correction for Unbound Fraction in Hepatocyte Incubations Using Microsomal Binding or Drug Lipophilicity Data
      Peter J. Kilford, Michael Gertz, J. Brian Houston and Aleksandra Galetin
      Drug Metabolism and Disposition July 2008, 36 (7) 1194-1197; DOI: https://doi.org/10.1124/dmd.108.020834
  6. Kim, Young C.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  7. Kitamura, Shigeyuki

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  8. Koudriakova, Tatiana

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  9. Koup, Jeffrey R.

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  10. Kumar, Vikas

    1. You have access
      Differential Genotype Dependent Inhibition of CYP2C9 in Humans
      Vikas Kumar, Richard C. Brundage, William S. Oetting, Ilo E. Leppik and Timothy S. Tracy
      Drug Metabolism and Disposition July 2008, 36 (7) 1242-1248; DOI: https://doi.org/10.1124/dmd.108.020396

L

  1. Lago, Michael

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  2. Lee, Francis Y. F.

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  3. Lee, Frank W.

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole
      Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
    2. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. III. In Vitro-in Vivo Correlation with Fluconazole
      Chuang Lu, Cicely Berg, Shimoga R. Prakash, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1261-1266; DOI: https://doi.org/10.1124/dmd.107.019000
  4. Lee, Inchul

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  5. Lee, Joseph H.

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  6. Lee, Myung G.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  7. Leppik, Ilo E.

    1. You have access
      Differential Genotype Dependent Inhibition of CYP2C9 in Humans
      Vikas Kumar, Richard C. Brundage, William S. Oetting, Ilo E. Leppik and Timothy S. Tracy
      Drug Metabolism and Disposition July 2008, 36 (7) 1242-1248; DOI: https://doi.org/10.1124/dmd.108.020396
  8. Li, Qi

    1. You have access
      Osmotic Regulation of a Novel Flavin-Containing Monooxygenase in Primary Cultured Cells from Rainbow Trout (Oncorhynchus mykiss)
      Gabriela Rodríguez-Fuentes, Rosaura Aparicio-Fabre, Qi Li and Daniel Schlenk
      Drug Metabolism and Disposition July 2008, 36 (7) 1212-1217; DOI: https://doi.org/10.1124/dmd.107.019968
  9. Li, Wenying

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  10. Lien, Gregory J.

    1. You have access
      Use of Online Microdialysis Sampling to Determine the in Vivo Rate of Phenol Glucuronidation in Rainbow Trout
      John W. Nichols, Alex D. Hoffman, Patrick N. Fitzsimmons, Gregory J. Lien and Correne T. Jenson
      Drug Metabolism and Disposition July 2008, 36 (7) 1406-1413; DOI: https://doi.org/10.1124/dmd.107.020123
  11. Lim, Lee-Yong

    1. You have access
      Effects of Spice Constituents on P-Glycoprotein-Mediated Transport and CYP3A4-Mediated Metabolism in Vitro
      Wenxia Zhang and Lee-Yong Lim
      Drug Metabolism and Disposition July 2008, 36 (7) 1283-1290; DOI: https://doi.org/10.1124/dmd.107.019737
  12. Lombardo, Franco

    1. You have access
      Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
      R. Scott Obach, Franco Lombardo and Nigel J. Waters
      Drug Metabolism and Disposition July 2008, 36 (7) 1385-1405; DOI: https://doi.org/10.1124/dmd.108.020479
  13. Lowery, Shane M.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  14. Lu, Chuang

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole
      Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
    2. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. III. In Vitro-in Vivo Correlation with Fluconazole
      Chuang Lu, Cicely Berg, Shimoga R. Prakash, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1261-1266; DOI: https://doi.org/10.1124/dmd.107.019000
  15. Luo, Roger

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267

M

  1. MacLean, Caroline

    1. You have access
      Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats
      Caroline MacLean, Ulla Moenning, Andreas Reichel and Gert Fricker
      Drug Metabolism and Disposition July 2008, 36 (7) 1249-1254; DOI: https://doi.org/10.1124/dmd.108.020859
  2. Makino, Toshiaki

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  3. Manning, James A.

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
    2. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  4. McCann, Betty

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  5. Mcconn, Donavon J.

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198
  6. McLaughlin, Lesley A.

    1. You have access
      Functional Expression and Comparative Characterization of Nine Murine Cytochromes P450 by Fluorescent Inhibition Screening
      Lesley A. McLaughlin, Leslie J. Dickmann, C. Roland Wolf and Colin J. Henderson
      Drug Metabolism and Disposition July 2008, 36 (7) 1322-1331; DOI: https://doi.org/10.1124/dmd.108.021261
  7. Mizukami, Hajime

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  8. Moenning, Ulla

    1. You have access
      Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats
      Caroline MacLean, Ulla Moenning, Andreas Reichel and Gert Fricker
      Drug Metabolism and Disposition July 2008, 36 (7) 1249-1254; DOI: https://doi.org/10.1124/dmd.108.020859
  9. Muir, Keith T.

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198

N

  1. Negishi, Masahiko

    1. You have access
      The Antiapoptotic Factor Growth Arrest and DNA-Damage-Inducible 45 β Regulates the Nuclear Receptor Constitutive Active/Androstane Receptor-Mediated Transcription
      Yukio Yamamoto and Masahiko Negishi
      Drug Metabolism and Disposition July 2008, 36 (7) 1189-1193; DOI: https://doi.org/10.1124/dmd.108.020628
  2. Nichols, John W.

    1. You have access
      Use of Online Microdialysis Sampling to Determine the in Vivo Rate of Phenol Glucuronidation in Rainbow Trout
      John W. Nichols, Alex D. Hoffman, Patrick N. Fitzsimmons, Gregory J. Lien and Correne T. Jenson
      Drug Metabolism and Disposition July 2008, 36 (7) 1406-1413; DOI: https://doi.org/10.1124/dmd.107.020123
  3. Nieman, James A.

    1. You have access
      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  4. Nitta, Kayoko

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075

O

  1. Obach, R. Scott

    1. You have access
      Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
      R. Scott Obach, Franco Lombardo and Nigel J. Waters
      Drug Metabolism and Disposition July 2008, 36 (7) 1385-1405; DOI: https://doi.org/10.1124/dmd.108.020479
  2. Oetting, William S.

    1. You have access
      Differential Genotype Dependent Inhibition of CYP2C9 in Humans
      Vikas Kumar, Richard C. Brundage, William S. Oetting, Ilo E. Leppik and Timothy S. Tracy
      Drug Metabolism and Disposition July 2008, 36 (7) 1242-1248; DOI: https://doi.org/10.1124/dmd.108.020396
  3. Ogan, Marc

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  4. Ohashi, Rikiya

    1. You have access
      Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes
      Hajime Fukuda, Rikiya Ohashi, Minoru Tsuda-Tsukimoto and Ikumi Tamai
      Drug Metabolism and Disposition July 2008, 36 (7) 1275-1282; DOI: https://doi.org/10.1124/dmd.107.019026
  5. Ohta, Shigeru

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  6. Ohtake, Nobuhiro

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089

P

  1. Paine, Stuart W.

    1. You have access
      Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
      Stuart W. Paine, Alison J. Parker, Philip Gardiner, Peter J. H. Webborn and Robert J. Riley
      Drug Metabolism and Disposition July 2008, 36 (7) 1365-1374; DOI: https://doi.org/10.1124/dmd.107.019455
  2. Parker, Alison J.

    1. You have access
      Rate-Limiting Steps in Hepatic Drug Clearance: Comparison of Hepatocellular Uptake and Metabolism with Microsomal Metabolism of Saquinavir, Nelfinavir, and Ritonavir
      Alison J. Parker and J. Brian Houston
      Drug Metabolism and Disposition July 2008, 36 (7) 1375-1384; DOI: https://doi.org/10.1124/dmd.108.020917
    2. You have access
      Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
      Stuart W. Paine, Alison J. Parker, Philip Gardiner, Peter J. H. Webborn and Robert J. Riley
      Drug Metabolism and Disposition July 2008, 36 (7) 1365-1374; DOI: https://doi.org/10.1124/dmd.107.019455
  3. Peng, Ying

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  4. Perkins, Everett J.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  5. Ponsler, G. Douglas

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  6. Prakash, Chandra

    1. You have access
      Disposition of Lasofoxifene, a Next-Generation Selective Estrogen Receptor Modulator, in Healthy Male Subjects
      Chandra Prakash, Kim A. Johnson and Mark J. Gardner
      Drug Metabolism and Disposition July 2008, 36 (7) 1218-1226; DOI: https://doi.org/10.1124/dmd.108.020404
  7. Prakash, Shimoga R.

    1. You have access
      Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. III. In Vitro-in Vivo Correlation with Fluconazole
      Chuang Lu, Cicely Berg, Shimoga R. Prakash, Frank W. Lee and Suresh K. Balani
      Drug Metabolism and Disposition July 2008, 36 (7) 1261-1266; DOI: https://doi.org/10.1124/dmd.107.019000

Q

  1. Qiu, Furong

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  2. Quesada, Arnulfo

    1. You have access
      The Mibefradil Derivative NNC55-0396, a Specific T-Type Calcium Channel Antagonist, Exhibits Less CYP3A4 Inhibition than Mibefradil
      Peter H. Bui, Arnulfo Quesada, Adrian Handforth and Oliver Hankinson
      Drug Metabolism and Disposition July 2008, 36 (7) 1291-1299; DOI: https://doi.org/10.1124/dmd.107.020115

R

  1. Reese, Melinda J.

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198
  2. Reichel, Andreas

    1. You have access
      Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats
      Caroline MacLean, Ulla Moenning, Andreas Reichel and Gert Fricker
      Drug Metabolism and Disposition July 2008, 36 (7) 1249-1254; DOI: https://doi.org/10.1124/dmd.108.020859
  3. Reitberg, Donald P.

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  4. Riley, Robert J.

    1. You have access
      Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
      Stuart W. Paine, Alison J. Parker, Philip Gardiner, Peter J. H. Webborn and Robert J. Riley
      Drug Metabolism and Disposition July 2008, 36 (7) 1365-1374; DOI: https://doi.org/10.1124/dmd.107.019455
  5. Rodríguez-Fuentes, Gabriela

    1. You have access
      Osmotic Regulation of a Novel Flavin-Containing Monooxygenase in Primary Cultured Cells from Rainbow Trout (Oncorhynchus mykiss)
      Gabriela Rodríguez-Fuentes, Rosaura Aparicio-Fabre, Qi Li and Daniel Schlenk
      Drug Metabolism and Disposition July 2008, 36 (7) 1212-1217; DOI: https://doi.org/10.1124/dmd.107.019968
  6. Romero, David

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  7. Ruterbories, Kenneth J.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248

S

  1. Schlenk, Daniel

    1. You have access
      Osmotic Regulation of a Novel Flavin-Containing Monooxygenase in Primary Cultured Cells from Rainbow Trout (Oncorhynchus mykiss)
      Gabriela Rodríguez-Fuentes, Rosaura Aparicio-Fabre, Qi Li and Daniel Schlenk
      Drug Metabolism and Disposition July 2008, 36 (7) 1212-1217; DOI: https://doi.org/10.1124/dmd.107.019968
  2. Shin, Wan G.

    1. You have access
      Pharmacokinetic Parameters of Chlorzoxazone and Its Main Metabolite, 6-Hydroxychlorzoxazone, after Intravenous and Oral Administration of Chlorzoxazone to Liver Cirrhotic Rats with Diabetes Mellitus
      Choong Y. Ahn, Soo K. Bae, Young S. Jung, Inchul Lee, Young C. Kim, Myung G. Lee and Wan G. Shin
      Drug Metabolism and Disposition July 2008, 36 (7) 1233-1241; DOI: https://doi.org/10.1124/dmd.107.017442
  3. Skaptason, Judith

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  4. Smith, Bill J.

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  5. Smith, Evan

    1. You have access
      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  6. St. John-Williams, Lisa

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198
  7. Sugihara, Kazumi

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  8. Sun, Jianguo

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  9. Suzuki, Hiroshi

    1. You have access
      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
      Naoko Yoshida, Tappei Takada, Yoshikazu Yamamura, Isao Adachi, Hiroshi Suzuki and Junichi Kawakami
      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513

T

  1. Takada, Tappei

    1. You have access
      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
      Naoko Yoshida, Tappei Takada, Yoshikazu Yamamura, Isao Adachi, Hiroshi Suzuki and Junichi Kawakami
      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513
  2. Tamai, Ikumi

    1. You have access
      Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes
      Hajime Fukuda, Rikiya Ohashi, Minoru Tsuda-Tsukimoto and Ikumi Tamai
      Drug Metabolism and Disposition July 2008, 36 (7) 1275-1282; DOI: https://doi.org/10.1124/dmd.107.019026
  3. Tanoue, Chiaki

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  4. Tayama, Yoshitaka

    1. You have access
      Aldehyde Oxidase-Catalyzed Metabolism of N1-Methylnicotinamide in Vivo and in Vitro in Chimeric Mice with Humanized Liver
      Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Tae Inoue, Toru Horie and Shigeru Ohta
      Drug Metabolism and Disposition July 2008, 36 (7) 1202-1205; DOI: https://doi.org/10.1124/dmd.107.019075
  5. Tracy, Timothy S.

    1. You have access
      Differential Genotype Dependent Inhibition of CYP2C9 in Humans
      Vikas Kumar, Richard C. Brundage, William S. Oetting, Ilo E. Leppik and Timothy S. Tracy
      Drug Metabolism and Disposition July 2008, 36 (7) 1242-1248; DOI: https://doi.org/10.1124/dmd.108.020396
  6. Tsuchiya, Naoko

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  7. Tsuda-Tsukimoto, Minoru

    1. You have access
      Effect of Plasma Protein Binding on in Vitro-in Vivo Correlation of Biliary Excretion of Drugs Evaluated by Sandwich-Cultured Rat Hepatocytes
      Hajime Fukuda, Rikiya Ohashi, Minoru Tsuda-Tsukimoto and Ikumi Tamai
      Drug Metabolism and Disposition July 2008, 36 (7) 1275-1282; DOI: https://doi.org/10.1124/dmd.107.019026

W

  1. Wang, Guangji

    1. You have access
      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  2. Wang, Lifei

    1. You have access
      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  3. Watanabe, Akito

    1. You have access
      Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury
      Toshiaki Makino, Nobuhiro Ohtake, Akito Watanabe, Naoko Tsuchiya, Sachiko Imamura, Seiichi Iizuka, Makoto Inoue and Hajime Mizukami
      Drug Metabolism and Disposition July 2008, 36 (7) 1438-1443; DOI: https://doi.org/10.1124/dmd.108.021089
  4. Waters, Nigel J.

    1. You have access
      Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
      R. Scott Obach, Franco Lombardo and Nigel J. Waters
      Drug Metabolism and Disposition July 2008, 36 (7) 1385-1405; DOI: https://doi.org/10.1124/dmd.108.020479
  5. Webborn, Peter J. H.

    1. You have access
      Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
      Stuart W. Paine, Alison J. Parker, Philip Gardiner, Peter J. H. Webborn and Robert J. Riley
      Drug Metabolism and Disposition July 2008, 36 (7) 1365-1374; DOI: https://doi.org/10.1124/dmd.107.019455
  6. Williams, Eric T.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  7. Wolf, C. Roland

    1. You have access
      Functional Expression and Comparative Characterization of Nine Murine Cytochromes P450 by Fluorescent Inhibition Screening
      Lesley A. McLaughlin, Leslie J. Dickmann, C. Roland Wolf and Colin J. Henderson
      Drug Metabolism and Disposition July 2008, 36 (7) 1322-1331; DOI: https://doi.org/10.1124/dmd.108.021261
  8. Wrighton, Steven A.

    1. You have access
      The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
      Eric T. Williams, Karen O. Jones, G. Douglas Ponsler, Shane M. Lowery, Everett J. Perkins, Steven A. Wrighton, Kenneth J. Ruterbories, Miho Kazui and Nagy A. Farid
      Drug Metabolism and Disposition July 2008, 36 (7) 1227-1232; DOI: https://doi.org/10.1124/dmd.107.020248
  9. Wu, Chiyuan

    1. You have access
      Metabolism and Disposition of Dasatinib after Oral Administration to Humans
      Lisa J. Christopher, Donghui Cui, Chiyuan Wu, Roger Luo, James A. Manning, Samuel J. Bonacorsi, Michael Lago, Alban Allentoff, Francis Y. F. Lee, Betty McCann, Susan Galbraith, Donald P. Reitberg, Kan He, Anthony Barros, Anne Blackwood-Chirchir, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1357-1364; DOI: https://doi.org/10.1124/dmd.107.018267
  10. Wu, Ellen Y.

    1. You have access
      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121
  11. Wurm, Robert M.

    1. You have access
      An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction
      Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
      Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198

X

  1. Xiang, Cathie D.

    1. You have access
      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121

Y

  1. Yamamoto, Yukio

    1. You have access
      The Antiapoptotic Factor Growth Arrest and DNA-Damage-Inducible 45 β Regulates the Nuclear Receptor Constitutive Active/Androstane Receptor-Mediated Transcription
      Yukio Yamamoto and Masahiko Negishi
      Drug Metabolism and Disposition July 2008, 36 (7) 1189-1193; DOI: https://doi.org/10.1124/dmd.108.020628
  2. Yamamura, Yoshikazu

    1. You have access
      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
      Naoko Yoshida, Tappei Takada, Yoshikazu Yamamura, Isao Adachi, Hiroshi Suzuki and Junichi Kawakami
      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513
  3. Yamazaki, Shinji

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
  4. Ye, Zhi-wei

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      Cellular Accumulation of Cholyl-Glycylamido-Fluorescein in Sandwich-Cultured Rat Hepatocytes: Kinetic Characterization, Transport Mechanisms, and Effect of Human Immunodeficiency Virus Protease Inhibitors
      Zhi-wei Ye, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition July 2008, 36 (7) 1315-1321; DOI: https://doi.org/10.1124/dmd.107.019398
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      Inhibitory Effects of Terpenoids on Multidrug Resistance-Associated Protein 2- and Breast Cancer Resistance Protein-Mediated Transport
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      Drug Metabolism and Disposition July 2008, 36 (7) 1206-1211; DOI: https://doi.org/10.1124/dmd.107.019513

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      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  2. Zhang, Eric Y.

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      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121
  3. Zhang, Haiying

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      Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys
      Lisa J. Christopher, Donghui Cui, Wenying Li, Anthony Barros, Vinod K. Arora, Haiying Zhang, Lifei Wang, Donglu Zhang, James A. Manning, Kan He, Anthony M. Fletcher, Marc Ogan, Michael Lago, Samuel J. Bonacorsi, W. Griffith Humphreys and Ramaswamy A. Iyer
      Drug Metabolism and Disposition July 2008, 36 (7) 1341-1356; DOI: https://doi.org/10.1124/dmd.107.018234
  4. Zhang, Rong

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      Inhibitory Effects of Seven Components of Danshen Extract on Catalytic Activity of Cytochrome P450 Enzyme in Human Liver Microsomes
      Furong Qiu, Rong Zhang, Jianguo Sun, Jiye A, Haiping Hao, Ying Peng, Hua Ai and Guangji Wang
      Drug Metabolism and Disposition July 2008, 36 (7) 1308-1314; DOI: https://doi.org/10.1124/dmd.108.021030
  5. Zhang, Tao

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      Drug Transporter and Cytochrome P450 mRNA Expression in Human Ocular Barriers: Implications for Ocular Drug Disposition
      Tao Zhang, Cathie D. Xiang, David Gale, Samantha Carreiro, Ellen Y. Wu and Eric Y. Zhang
      Drug Metabolism and Disposition July 2008, 36 (7) 1300-1307; DOI: https://doi.org/10.1124/dmd.108.021121
  6. Zhang, Wenxia

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      Effects of Spice Constituents on P-Glycoprotein-Mediated Transport and CYP3A4-Mediated Metabolism in Vitro
      Wenxia Zhang and Lee-Yong Lim
      Drug Metabolism and Disposition July 2008, 36 (7) 1283-1290; DOI: https://doi.org/10.1124/dmd.107.019737
  7. Zhou, Sue

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      Bioactivation of Flutamide Metabolites by Human Liver Microsomes
      Ping Kang, Deepak Dalvie, Evan Smith, Sue Zhou, Alan Deese and James A. Nieman
      Drug Metabolism and Disposition July 2008, 36 (7) 1425-1437; DOI: https://doi.org/10.1124/dmd.108.020370
  8. Zou, Helen Y.

    1. You have access
      Pharmacokinetic-Pharmacodynamic Modeling of Biomarker Response and Tumor Growth Inhibition to an Orally Available cMet Kinase Inhibitor in Human Tumor Xenograft Mouse Models
      Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H. Lee, Helen Y. Zou, James G. Christensen, Jeffrey R. Koup, Bill J. Smith and Tatiana Koudriakova
      Drug Metabolism and Disposition July 2008, 36 (7) 1267-1274; DOI: https://doi.org/10.1124/dmd.107.019711
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Drug Metabolism and Disposition: 36 (7)
Drug Metabolism and Disposition
Vol. 36, Issue 7
1 Jul 2008
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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