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An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction

Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
Drug Metabolism and Disposition July 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198

Article Information

vol. 36 no. 7 1198-1201
DOI 
https://doi.org/10.1124/dmd.107.020198
PubMed 
18420781
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 9, 2008
  • Accepted April 15, 2008
  • Published online June 19, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Melinda J. Reese,
  2. Robert M. Wurm,
  3. Keith T. Muir,
  4. Grant T. Generaux,
  5. Lisa St. John-Williams and
  6. Donavon J. Mcconn
  1. Departments of Drug Metabolism and Pharmacokinetics (M.J.R., R.M.W., G.T.G., L.S.-W.) and Clinical Pharmacology and Discovery Medicine (K.T.M.), GlaxoSmithKline, Research Triangle Park, North Carolina; and Department of Drug Metabolism and Pharmacokinetics, Theravance, Inc., South San Francisco, California (D.J.M.)
  1. Address correspondence to:
    Melinda J. Reese, Preclinical Drug Metabolism and Pharmacokinetics, GlaxoSmithKline, Inc., Room MAI.A227D, Research Triangle Park, NC 27709. E-mail: mindy.j.reese{at}gsk.com
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OtherShort Communication

An in Vitro Mechanistic Study to Elucidate the Desipramine/Bupropion Clinical Drug-Drug Interaction

Melinda J. Reese, Robert M. Wurm, Keith T. Muir, Grant T. Generaux, Lisa St. John-Williams and Donavon J. Mcconn
Drug Metabolism and Disposition July 1, 2008, 36 (7) 1198-1201; DOI: https://doi.org/10.1124/dmd.107.020198
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