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Research ArticleArticle

Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole

Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
Drug Metabolism and Disposition July 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796

Article Information

vol. 36 no. 7 1255-1260
DOI 
https://doi.org/10.1124/dmd.107.018796
PubMed 
18381489
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 7, 2007
  • Accepted March 31, 2008
  • Published online June 19, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Chuang Lu,
  2. Panos Hatsis,
  3. Cicely Berg,
  4. Frank W. Lee and
  5. Suresh K. Balani
  1. Drug Metabolism and Pharmacokinetics, Drug Safety and Disposition, Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts
  1. Address correspondence to:
    Dr. Chuang Lu, Millennium Pharmaceuticals, Inc., 40 Landsdowne St., Cambridge, MA 02139. E-mail: chuang.lu{at}mpi.com
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Research ArticleArticle

Prediction of Pharmacokinetic Drug-Drug Interactions Using Human Hepatocyte Suspension in Plasma and Cytochrome P450 Phenotypic Data. II. In Vitro-in Vivo Correlation with Ketoconazole

Chuang Lu, Panos Hatsis, Cicely Berg, Frank W. Lee and Suresh K. Balani
Drug Metabolism and Disposition July 1, 2008, 36 (7) 1255-1260; DOI: https://doi.org/10.1124/dmd.107.018796
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