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Research ArticleArticle

Effects of Ketoconazole and Quinidine on Pharmacokinetics of Pactimibe and Its Plasma Metabolite, R-125528, in Humans

Masakatsu Kotsuma, Taro Tokui, Stefan Freudenthaler and Kenji Nishimura
Drug Metabolism and Disposition August 2008, 36 (8) 1505-1511; DOI: https://doi.org/10.1124/dmd.108.021394

Article Information

vol. 36 no. 8 1505-1511
DOI 
https://doi.org/10.1124/dmd.108.021394
PubMed 
18448569
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 10, 2008
  • Accepted April 28, 2008
  • Published online July 21, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Masakatsu Kotsuma,
  2. Taro Tokui,
  3. Stefan Freudenthaler and
  4. Kenji Nishimura
  1. Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan (M.K., T.T., K.N.); and Risk Management, Daiichi Sankyo Europe GmbH, Munich, Germany (S.F.)
  1. Address correspondence to:
    Dr. Masakatsu Kotsuma, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan. E-mail: kotsuma.masakatsu.gu{at}daiichisankyo.co.jp
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Research ArticleArticle

Effects of Ketoconazole and Quinidine on Pharmacokinetics of Pactimibe and Its Plasma Metabolite, R-125528, in Humans

Masakatsu Kotsuma, Taro Tokui, Stefan Freudenthaler and Kenji Nishimura
Drug Metabolism and Disposition August 1, 2008, 36 (8) 1505-1511; DOI: https://doi.org/10.1124/dmd.108.021394
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