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A Comprehensive in Vitro and in Silico Analysis of Antibiotics That Activate Pregnane X Receptor and Induce CYP3A4 in Liver and Intestine

Kazuto Yasuda, Aarati Ranade, Raman Venkataramanan, Stephen Strom, Jonathan Chupka, Sean Ekins, Erin Schuetz and Kenneth Bachmann
Drug Metabolism and Disposition August 2008, 36 (8) 1689-1697; DOI: https://doi.org/10.1124/dmd.108.020701

 

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Research ArticleArticle

A Comprehensive in Vitro and in Silico Analysis of Antibiotics That Activate Pregnane X Receptor and Induce CYP3A4 in Liver and Intestine

Kazuto Yasuda, Aarati Ranade, Raman Venkataramanan, Stephen Strom, Jonathan Chupka, Sean Ekins, Erin Schuetz and Kenneth Bachmann
Drug Metabolism and Disposition August 1, 2008, 36 (8) 1689-1697; DOI: https://doi.org/10.1124/dmd.108.020701
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