Advertisement
Research ArticleArticle

A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro

Odette A. Fahmi, Tristan S. Maurer, Mary Kish, Edwin Cardenas, Sherri Boldt and David Nettleton
Drug Metabolism and Disposition August 2008, 36 (8) 1698-1708; DOI: https://doi.org/10.1124/dmd.107.018663

Article Information

vol. 36 no. 8 1698-1708
DOI 
https://doi.org/10.1124/dmd.107.018663
PubMed 
18490437
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 30, 2007
  • Accepted May 16, 2008
  • Published online July 21, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Odette A. Fahmi,
  2. Tristan S. Maurer,
  3. Mary Kish,
  4. Edwin Cardenas,
  5. Sherri Boldt and
  6. David Nettleton
  1. Department of Pharmacokinetics, Dynamics, and Metabolism, Pfizer Global Research & Development, Groton, Connecticut (O.A.F., T.S.M., M.K., S.B.); Novartis Institutes for BioMedical Research, Cambridge, Massachusetts (D.N.); and University of Connecticut, Storrs, Connecticut (E.C.)
  1. Address correspondence to:
    Dr. Odette Fahmi, Department of Pharmacokinetics, Dynamics, and Metabolism, Mail Stop MS-8118W-128, Pfizer Global Research & Development, Eastern Point Rd., Groton, CT 06340. E-mail: odette.a.fahmi{at}pfizer.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to January 2023

AbstractFullPdf
Aug 201715232
Sep 201704129
Oct 201724817
Nov 201725939
Dec 201703031
Jan 201823125
Feb 201804038
Mar 201836641
Apr 201813036
May 201803124
Jun 201814428
Jul 201803324
Aug 201804746
Sep 201802841
Oct 201804328
Nov 201806530
Dec 2018402625
Jan 2019461613
Feb 2019521013
Mar 2019331015
Apr 2019322323
May 2019302820
Jun 201931918
Jul 2019312210
Aug 201935910
Oct 201932912
Nov 20192441
Dec 2019272315
Jan 2020441710
Feb 202016119
Mar 2020682215
May 202025178
Jun 202044108
Jul 202026106
Aug 202034116
Sep 202045129
Oct 202030228
Nov 202025811
Dec 2020301511
Jan 2021334714
Feb 2021366014
Mar 202180159
Apr 202161118
May 2021902514
Jun 2021753616
Jul 202132117
Aug 202138416
Sep 2021493410
Oct 202141105
Nov 2021421716
Dec 202138138
Jan 2022541611
Feb 20224068
Mar 2022792423
Apr 2022411819
May 2022651714
Jun 20226098
Jul 2022341823
Aug 2022573012
Sep 2022753914
Oct 2022505919
Nov 20225677
Dec 20223179
Jan 202368217

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro

Odette A. Fahmi, Tristan S. Maurer, Mary Kish, Edwin Cardenas, Sherri Boldt and David Nettleton
Drug Metabolism and Disposition August 1, 2008, 36 (8) 1698-1708; DOI: https://doi.org/10.1124/dmd.107.018663
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo

Jump to section

Advertisement