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Research ArticleArticle

Deletion of the NADPH-Cytochrome P450 Reductase Gene in Cardiomyocytes Does Not Protect Mice against Doxorubicin-Mediated Acute Cardiac Toxicity

Cheng Fang, Jun Gu, Fang Xie, Melissa Behr, Weizhu Yang, E. Dale Abel and Xinxin Ding
Drug Metabolism and Disposition August 2008, 36 (8) 1722-1728; DOI: https://doi.org/10.1124/dmd.108.021881

Article Information

vol. 36 no. 8 1722-1728
DOI 
https://doi.org/10.1124/dmd.108.021881
PubMed 
18463197
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 15, 2008
  • Accepted May 5, 2008
  • Published online July 21, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Cheng Fang,
  2. Jun Gu,
  3. Fang Xie,
  4. Melissa Behr,
  5. Weizhu Yang,
  6. E. Dale Abel and
  7. Xinxin Ding
  1. Wadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, Albany, New York (C.F., J.G., F.X., M.B., W.Y., X.D.); and Division of Endocrinology, Metabolism, and Diabetes and Program in Human Molecular Biology and Genetics, University of Utah School of Medicine, Salt Lake City, Utah (E.D.A.)
  1. Address correspondence to:
    Xinxin Ding, Wadsworth Center, New York State Department of Health, Empire State Plaza, Box 509, Albany, NY 12201-0509. E-mail: xding{at}wadsworth.org
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Research ArticleArticle

Deletion of the NADPH-Cytochrome P450 Reductase Gene in Cardiomyocytes Does Not Protect Mice against Doxorubicin-Mediated Acute Cardiac Toxicity

Cheng Fang, Jun Gu, Fang Xie, Melissa Behr, Weizhu Yang, E. Dale Abel and Xinxin Ding
Drug Metabolism and Disposition August 1, 2008, 36 (8) 1722-1728; DOI: https://doi.org/10.1124/dmd.108.021881
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