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Research ArticleArticle

Binding of Pimecrolimus and Tacrolimus to Skin and Plasma Proteins: Implications for Systemic Exposure after Topical Application

H. Markus Weiss, Marcel Fresneau, Thomas Moenius, Anton Stuetz and Andreas Billich
Drug Metabolism and Disposition September 2008, 36 (9) 1812-1818; DOI: https://doi.org/10.1124/dmd.108.021915

Article Information

vol. 36 no. 9 1812-1818
DOI 
https://doi.org/10.1124/dmd.108.021915
PubMed 
18524871
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 17, 2008
  • Accepted June 3, 2008
  • Published online August 20, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. H. Markus Weiss,
  2. Marcel Fresneau,
  3. Thomas Moenius,
  4. Anton Stuetz and
  5. Andreas Billich
  1. Novartis Pharma AG, Basel, Switzerland (H.M.W., M.F., T.M., A.B.); and Novartis Institutes for BioMedical Research, Vienna, Austria (A.S.)
  1. Address correspondence to:
    Dr. H. Markus Weiss, Novartis Pharma AG, DMPK, WSJ-210.4.25, CH-4002, Basel, Switzerland. E-mail: markus.weiss{at}novartis.com
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Research ArticleArticle

Binding of Pimecrolimus and Tacrolimus to Skin and Plasma Proteins: Implications for Systemic Exposure after Topical Application

H. Markus Weiss, Marcel Fresneau, Thomas Moenius, Anton Stuetz and Andreas Billich
Drug Metabolism and Disposition September 1, 2008, 36 (9) 1812-1818; DOI: https://doi.org/10.1124/dmd.108.021915
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