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Research ArticleArticle

Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret

Elisabeth Minthorn, Thomas Mencken, Andrew G. King, Art Shu, David Rominger, Richard R. Gontarek, Chao Han, Ramesh Bambal and Charles B. Davis
Drug Metabolism and Disposition September 2008, 36 (9) 1846-1852; DOI: https://doi.org/10.1124/dmd.108.021758

Article Information

vol. 36 no. 9 1846-1852
DOI 
https://doi.org/10.1124/dmd.108.021758
PubMed 
18556439
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 3, 2008
  • Accepted June 10, 2008
  • Published online August 20, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Elisabeth Minthorn,
  2. Thomas Mencken,
  3. Andrew G. King,
  4. Art Shu,
  5. David Rominger,
  6. Richard R. Gontarek,
  7. Chao Han,
  8. Ramesh Bambal and
  9. Charles B. Davis
  1. Drug Metabolism and Pharmacokinetics (E.M., T.M., C.H., R.B., C.B.D.), Oncology Biology (A.G.K.), Medicinal Chemistry (A.S.), and Enzymology and Mechanistic Pharmacology (D.R., R.R.G.), Drug Discovery, GlaxoSmithKline, Collegeville, Pennsylvania
  1. Address correspondence to:
    Elisabeth Minthorn, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA 19426. E-mail: elisabeth.a.minthorn{at}gsk.com
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Research ArticleArticle

Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret

Elisabeth Minthorn, Thomas Mencken, Andrew G. King, Art Shu, David Rominger, Richard R. Gontarek, Chao Han, Ramesh Bambal and Charles B. Davis
Drug Metabolism and Disposition September 1, 2008, 36 (9) 1846-1852; DOI: https://doi.org/10.1124/dmd.108.021758
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