Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret

Elisabeth Minthorn, Thomas Mencken, Andrew G. King, Art Shu, David Rominger, Richard R. Gontarek, Chao Han, Ramesh Bambal and Charles B. Davis
Drug Metabolism and Disposition September 2008, 36 (9) 1846-1852; DOI: https://doi.org/10.1124/dmd.108.021758
Elisabeth Minthorn
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas Mencken
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew G. King
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Art Shu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Rominger
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard R. Gontarek
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chao Han
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ramesh Bambal
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charles B. Davis
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 36 no. 9 1846-1852
DOI 
https://doi.org/10.1124/dmd.108.021758
PubMed 
18556439

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 3, 2008
  • Accepted June 10, 2008
  • Published online August 20, 2008.

Article Versions

  • Earlier version (June 12, 2008 - 10:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Elisabeth Minthorn,
  2. Thomas Mencken,
  3. Andrew G. King,
  4. Art Shu,
  5. David Rominger,
  6. Richard R. Gontarek,
  7. Chao Han,
  8. Ramesh Bambal and
  9. Charles B. Davis
  1. Drug Metabolism and Pharmacokinetics (E.M., T.M., C.H., R.B., C.B.D.), Oncology Biology (A.G.K.), Medicinal Chemistry (A.S.), and Enzymology and Mechanistic Pharmacology (D.R., R.R.G.), Drug Discovery, GlaxoSmithKline, Collegeville, Pennsylvania
  1. Address correspondence to:
    Elisabeth Minthorn, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA 19426. E-mail: elisabeth.a.minthorn{at}gsk.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to May 2023

AbstractFullPdf
Aug 20172145
Sep 20170117
Oct 20170143
Nov 20174196
Dec 20170164
Jan 20182225
Feb 20182215
Mar 20182149
Apr 20183174
May 20185163
Jun 20181122
Jul 20182127
Aug 20181124
Sep 2018032
Oct 2018093
Nov 2018283
Dec 2018913
Jan 2019503
Feb 20191203
Mar 20191204
Apr 201914010
May 20191616
Jun 20192011
Jul 20192324
Aug 20191601
Oct 20192602
Nov 20192412
Dec 20192413
Jan 20202409
Feb 2020801
Mar 20201301
May 2020800
Jun 2020600
Jul 20201112
Aug 2020703
Sep 20201730
Oct 20201563
Nov 2020500
Dec 20201502
Jan 20211053
Feb 20212256
Mar 20212622
Apr 2021910
May 2021720
Jun 20211720
Jul 2021832
Aug 2021922
Sep 2021921
Oct 20211810
Nov 20212013
Dec 20212711
Jan 20221421
Feb 20221321
Mar 2022811
Apr 20221221
May 20221211
Jun 20221200
Jul 20221117
Aug 20221313
Sep 2022911
Oct 20221710
Nov 202214210
Dec 20221413
Jan 20231730
Feb 2023324
Mar 2023920
Apr 20231016
May 20231612

PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 36 (9)
Drug Metabolism and Disposition
Vol. 36, Issue 9
1 Sep 2008
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret

Elisabeth Minthorn, Thomas Mencken, Andrew G. King, Art Shu, David Rominger, Richard R. Gontarek, Chao Han, Ramesh Bambal and Charles B. Davis
Drug Metabolism and Disposition September 1, 2008, 36 (9) 1846-1852; DOI: https://doi.org/10.1124/dmd.108.021758

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Pharmacokinetics and Brain Penetration of Casopitant, a Potent and Selective Neurokinin-1 Receptor Antagonist, in the Ferret

Elisabeth Minthorn, Thomas Mencken, Andrew G. King, Art Shu, David Rominger, Richard R. Gontarek, Chao Han, Ramesh Bambal and Charles B. Davis
Drug Metabolism and Disposition September 1, 2008, 36 (9) 1846-1852; DOI: https://doi.org/10.1124/dmd.108.021758
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Adipocyte PXR does not play an essential role in obesity.
  • CYP3A-mediated oxidation of DABE and BIBR0951
  • Biodistribution of Lipid in Rats
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics