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Research ArticleArticle

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

Nirmala Raghavan, Charles E. Frost, Zhigang Yu, Kan He, Haiying Zhang, W. Griffith Humphreys, Donald Pinto, Shiangyuan Chen, Samuel Bonacorsi, Pancras C. Wong and Donglu Zhang
Drug Metabolism and Disposition January 2009, 37 (1) 74-81; DOI: https://doi.org/10.1124/dmd.108.023143
Nirmala Raghavan
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Charles E. Frost
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Zhigang Yu
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Kan He
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Haiying Zhang
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W. Griffith Humphreys
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Donald Pinto
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Shiangyuan Chen
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Samuel Bonacorsi
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Pancras C. Wong
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Donglu Zhang
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Article Information

vol. 37 no. 1 74-81
DOI 
https://doi.org/10.1124/dmd.108.023143
PubMed 
18832478

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 26, 2008
  • Accepted October 1, 2008
  • Published online December 23, 2008.

Article Versions

  • Earlier version (October 2, 2008 - 08:37).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nirmala Raghavan,
  2. Charles E. Frost,
  3. Zhigang Yu,
  4. Kan He,
  5. Haiying Zhang,
  6. W. Griffith Humphreys,
  7. Donald Pinto,
  8. Shiangyuan Chen,
  9. Samuel Bonacorsi,
  10. Pancras C. Wong and
  11. Donglu Zhang
  1. Pharmaceutical Candidate Optimization (N.R., K.H., H.Z., W.G.H., D.Z.), Discovery Medicine and Clinical Pharmacology (C.E.F., Z.Y.), Discovery Chemistry and Biology (D.P., S.C., S.B., P.C.W.), Bristol-Myers Squibb Research and Development, Princeton, New Jersey
  1. Address correspondence to:
    Dr. Donglu Zhang, PO Box 4000, Pharmaceutical Candidate Optimization, Bristol-Myers Squibb Research and Development, Princeton, NJ 08543-4000. E-mail: donglu.zhang{at}bms.com
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Drug Metabolism and Disposition: 37 (1)
Drug Metabolism and Disposition
Vol. 37, Issue 1
1 Jan 2009
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Research ArticleArticle

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

Nirmala Raghavan, Charles E. Frost, Zhigang Yu, Kan He, Haiying Zhang, W. Griffith Humphreys, Donald Pinto, Shiangyuan Chen, Samuel Bonacorsi, Pancras C. Wong and Donglu Zhang
Drug Metabolism and Disposition January 1, 2009, 37 (1) 74-81; DOI: https://doi.org/10.1124/dmd.108.023143

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Research ArticleArticle

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

Nirmala Raghavan, Charles E. Frost, Zhigang Yu, Kan He, Haiying Zhang, W. Griffith Humphreys, Donald Pinto, Shiangyuan Chen, Samuel Bonacorsi, Pancras C. Wong and Donglu Zhang
Drug Metabolism and Disposition January 1, 2009, 37 (1) 74-81; DOI: https://doi.org/10.1124/dmd.108.023143
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