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Research ArticleArticle

Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes

Lu Gan, Lisa L. von Moltke, Lauren A. Trepanier, Jerold S. Harmatz, David J. Greenblatt and Michael H. Court
Drug Metabolism and Disposition January 2009, 37 (1) 90-96; DOI: https://doi.org/10.1124/dmd.108.023424

Article Information

vol. 37 no. 1 90-96
DOI 
https://doi.org/10.1124/dmd.108.023424
PubMed 
18838505
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 17, 2008
  • Accepted October 2, 2008
  • Published online December 23, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lu Gan,
  2. Lisa L. von Moltke,
  3. Lauren A. Trepanier,
  4. Jerold S. Harmatz,
  5. David J. Greenblatt and
  6. Michael H. Court
  1. Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts (L.G., L.L.v.M., J.S.H., D.J.G., M.H.C.); and Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin (L.A.T.)
  1. Address correspondence to:
    Michael H. Court, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111. E-mail: michael.court{at}tufts.edu
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Research ArticleArticle

Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes

Lu Gan, Lisa L. von Moltke, Lauren A. Trepanier, Jerold S. Harmatz, David J. Greenblatt and Michael H. Court
Drug Metabolism and Disposition January 1, 2009, 37 (1) 90-96; DOI: https://doi.org/10.1124/dmd.108.023424
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