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4-Hydroxy-2,2′,3,4′,5,5′,6-heptachlorobiphenyl-Mediated Decrease in Serum Thyroxine Level in Mice Occurs through Increase in Accumulation of Thyroxine in the Liver

Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
Drug Metabolism and Disposition October 2009, 37 (10) 2095-2102; DOI: https://doi.org/10.1124/dmd.109.028621

Article Information

vol. 37 no. 10 2095-2102
DOI 
https://doi.org/10.1124/dmd.109.028621
PubMed 
19589873
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 27, 2009
  • Accepted July 6, 2009
  • Published online September 18, 2009.

Article Versions

Copyright & Usage 
Copyright © 2009 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yoshihisa Kato,
  2. Koichi Haraguchi,
  3. Makiko Kubota,
  4. Yoshiki Seto,
  5. Shin-ichi Ikushiro,
  6. Toshiyuki Sakaki,
  7. Nobuyuki Koga,
  8. Shizuo Yamada and
  9. Masakuni Degawa
  1. Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki, Kagawa, Japan (Y.K.);
  2. Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan (K.H.);
  3. School of Pharmaceutical Sciences and Global Center of Excellence Program in the 21st Century, University of Shizuoka, Shizuoka, Japan (M.K., Y.S., S.Y., M.D.);
  4. Faculty of Engineering, Toyama Prefectural University, Toyama, Japan (S.I., T.S.); and
  5. Faculty of Nutritional Sciences, Nakamura Gakuen University, Fukuoka, Japan (N.K.)
  1. Address correspondence to:
    Yoshihisa Kato, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1, Shido, Sanuki, Kagawa 769-2193, Japan. E-mail: kato{at}kph.bunri-u.ac.jp
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4-Hydroxy-2,2′,3,4′,5,5′,6-heptachlorobiphenyl-Mediated Decrease in Serum Thyroxine Level in Mice Occurs through Increase in Accumulation of Thyroxine in the Liver

Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada and Masakuni Degawa
Drug Metabolism and Disposition October 1, 2009, 37 (10) 2095-2102; DOI: https://doi.org/10.1124/dmd.109.028621
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